OA10059A - Compositions and methods for treating infections caused by organisms sensitive to beta-lactam antibiotics - Google Patents

Compositions and methods for treating infections caused by organisms sensitive to beta-lactam antibiotics Download PDF

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Publication number
OA10059A
OA10059A OA59988A OA59988A OA10059A OA 10059 A OA10059 A OA 10059A OA 59988 A OA59988 A OA 59988A OA 59988 A OA59988 A OA 59988A OA 10059 A OA10059 A OA 10059A
Authority
OA
OAPI
Prior art keywords
lys
leu
ala
tyr
gly
Prior art date
Application number
OA59988A
Other languages
English (en)
Inventor
Richard P Darveau
James J Blake
L Cosand Wesley
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to PT96859A priority Critical patent/PT96859A/pt
Priority to NZ237202A priority patent/NZ237202A/en
Priority to CN91102223A priority patent/CN1054900A/zh
Priority to IL9734491A priority patent/IL97344A/en
Priority to PCT/US1991/001224 priority patent/WO1991012815A1/en
Priority to EP19910905923 priority patent/EP0516747A4/en
Priority to AU74856/91A priority patent/AU650262B2/en
Priority to IE063091A priority patent/IE910630A1/en
Priority to ZA911347A priority patent/ZA911347B/xx
Priority to CA002076529A priority patent/CA2076529A1/en
Priority to HU922720A priority patent/HUT63567A/hu
Priority to CS91477A priority patent/CZ47791A3/cs
Priority to JP91506018A priority patent/JPH05506645A/ja
Priority to PL91289414A priority patent/PL166731B1/pl
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Priority to OA59988A priority patent/OA10059A/en
Priority to FI923747A priority patent/FI923747A/fi
Priority to NO92923298A priority patent/NO923298L/no
Priority to US08/233,203 priority patent/US5409898A/en
Publication of OA10059A publication Critical patent/OA10059A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
OA59988A 1990-02-23 1991-04-12 Compositions and methods for treating infections caused by organisms sensitive to beta-lactam antibiotics OA10059A (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
PT96859A PT96859A (pt) 1990-02-23 1991-02-22 Processo para a preparacao de composicoes farmaceuticas e metodos para o tratamento de infeccoes provocadas por organismos sensiveis aos antibioticos beta-lactamicos
NZ237202A NZ237202A (en) 1990-02-23 1991-02-22 Composition containing beta-lactam antibiotic and cationic oligopeptide
CN91102223A CN1054900A (zh) 1990-02-23 1991-02-23 由对β-内酰胺抗生素敏感的微生物引起的感染的治疗方法及其组合物
IL9734491A IL97344A (en) 1990-02-23 1991-02-24 Synergistic preparations containing B-lactam antibiotics and cationic oligopeptides for the treatment of inflammation
CS91477A CZ47791A3 (en) 1990-02-23 1991-02-25 Preparations and methods of treating infections caused by organisms responsive to beta-lactam antibiotics
AU74856/91A AU650262B2 (en) 1990-02-23 1991-02-25 Compositions and methods for treating infections caused by organisms sensitive to beta -lactam antibiotics
IE063091A IE910630A1 (en) 1990-02-23 1991-02-25 COMPOSITIONS AND METHODS FOR TREATING INFECTIONS CAUSED BY¹ORGANISMS SENSITIVE TO ß-LACTAM ANTIBIOTICS
ZA911347A ZA911347B (en) 1990-02-23 1991-02-25 Compositions and methods for treating infections caused by organisms sensitive to"-lactam antibiotics
CA002076529A CA2076529A1 (en) 1990-02-23 1991-02-25 Compositions and methods for treating infections caused by organisms sensitive to beta-lactam antibiotics
PCT/US1991/001224 WO1991012815A1 (en) 1990-02-23 1991-02-25 COMPOSITIONS AND METHODS FOR TREATING INFECTIONS CAUSED BY ORGANISMS SENSITIVE TO β-LACTAM ANTIBIOTICS
EP19910905923 EP0516747A4 (en) 1990-02-23 1991-02-25 Compositions and methods for treating infections caused by organisms sensitive to -g(b)-lactam antibiotics
JP91506018A JPH05506645A (ja) 1990-02-23 1991-02-25 β―ラクタム抗生物質に感受性の生物により引き起こされる感染を治療するための組成物および方法
HU922720A HUT63567A (en) 1990-02-23 1991-02-25 Process for producing composition suitable for treating infections caused by organisms sensitive to beta-lactam antibiotics
PL91289414A PL166731B1 (pl) 1991-02-19 1991-03-14 Sposób wytwarzania środka do leczenia infekcji wywołanych przez organizmy wrażliwe na antybiotykiβ-laktamowe
OA59988A OA10059A (en) 1990-02-23 1991-04-12 Compositions and methods for treating infections caused by organisms sensitive to beta-lactam antibiotics
FI923747A FI923747A (fi) 1990-02-23 1992-08-20 Kompositioner och foerfaranden foer behandling av infektioner foerorsakade av organismer sensitiva foer b-laktamantibiotika
NO92923298A NO923298L (no) 1990-02-23 1992-08-21 Blandinger og fremgangsmaater for behandling av infeksjoner foraarsaket av organismer som er foelsomme for beta-laktam-antibiotika
US08/233,203 US5409898A (en) 1990-02-23 1994-04-26 Compositions and methods for treating infections caused by organisms sensitive to β-lactam antibiotics

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48402090A 1990-02-23 1990-02-23
US65532191A 1991-02-19 1991-02-19
OA59988A OA10059A (en) 1990-02-23 1991-04-12 Compositions and methods for treating infections caused by organisms sensitive to beta-lactam antibiotics

Publications (1)

Publication Number Publication Date
OA10059A true OA10059A (en) 1996-10-14

Family

ID=33314051

Family Applications (1)

Application Number Title Priority Date Filing Date
OA59988A OA10059A (en) 1990-02-23 1991-04-12 Compositions and methods for treating infections caused by organisms sensitive to beta-lactam antibiotics

Country Status (14)

Country Link
US (1) US5409898A (fi)
EP (1) EP0516747A4 (fi)
JP (1) JPH05506645A (fi)
CN (1) CN1054900A (fi)
AU (1) AU650262B2 (fi)
CA (1) CA2076529A1 (fi)
CZ (1) CZ47791A3 (fi)
FI (1) FI923747A (fi)
HU (1) HUT63567A (fi)
IE (1) IE910630A1 (fi)
IL (1) IL97344A (fi)
NZ (1) NZ237202A (fi)
OA (1) OA10059A (fi)
WO (1) WO1991012815A1 (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613734B2 (en) * 1988-01-06 2003-09-02 The Scripps Research Institute Peptides-containing liposomal surfactants
US5885965A (en) * 1991-11-01 1999-03-23 Periodontix, Inc. Anti-fungal D-amino acid histatin-based peptides
US5646119A (en) * 1991-11-01 1997-07-08 Periodontix, Inc. D-amino acid histatin-based peptides as anti-fungal and anti-bacterial agents
US6458349B1 (en) 1995-06-02 2002-10-01 Human Genome Sciences, Inc. Chemokine β-4 polypeptides
US6391589B1 (en) 1994-08-23 2002-05-21 Human Genome Sciences, Inc. Human chemokine beta-10 mutant polypeptides
US6174995B1 (en) 1994-08-23 2001-01-16 Haodong Li Human chemokines, CKβ4 and CKβ10/MCP-4
WO1996035804A1 (en) * 1995-05-08 1996-11-14 Merck & Co., Inc. A novel biochemical interaction in bacteria
US5747453A (en) * 1995-06-06 1998-05-05 Alza Corporation Method for increasing the electrotransport flux of polypeptides
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
US6503881B2 (en) * 1996-08-21 2003-01-07 Micrologix Biotech Inc. Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
US6180604B1 (en) 1996-08-21 2001-01-30 Micrologix Biotech Inc. Compositions and methods for treating infections using analogues of indolicidin
NL1008139C2 (nl) * 1998-01-27 1999-07-28 Stichting Tech Wetenschapp Antimicrobiële peptiden.
US7820619B1 (en) 1998-02-18 2010-10-26 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Antimicrobial peptides and derived metapeptides
WO1999042119A1 (en) 1998-02-18 1999-08-26 Harbor-Ucla Research And Education Institute Antimicrobial peptides and derived metapeptides
US6191168B1 (en) 1998-06-02 2001-02-20 Edward Rubenstein Methods for the use of nonprotein amino acids as therapeutic agents
US6835536B2 (en) 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
CA2457885A1 (en) 2001-08-24 2003-03-06 Micrologix Biotech Inc. Antimicrobial and anti-inflammatory peptides
AR039475A1 (es) 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR039774A1 (es) 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
AU2003225237A1 (en) 2002-05-01 2003-11-17 Human Genome Sciences, Inc. Antibodies that specifically bind to chemokine beta-4
KR20080032637A (ko) * 2005-07-27 2008-04-15 와이어쓰 이환식 6-알킬리덴-페넴 β-락타마제 저해제 및 β-락탐항생제 조합: 광범위 항생제
EP2536408A1 (en) * 2010-02-16 2012-12-26 Wockhardt Research Centre Efflux pump inhibitors
PE20140633A1 (es) 2010-11-19 2014-05-30 Eisai Randd Man Co Ltd Anticuerpos neutralizadores anti-ccl20
CN107320727A (zh) * 2016-04-29 2017-11-07 四川大学 抗菌肽与抗生素组合抗菌药物及其使用方法
US20230414719A1 (en) * 2020-11-09 2023-12-28 Arizona Board Of Regents On Behalf Of Arizona State University Methods of using platelet factor 4 as an antimicrobial agent

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE436645C (sv) * 1976-04-29 1996-07-22 Bonnierfoeretagen Ab Antigeniskt aktiv polypeptid, som kan användas vid cancerdiagnosticering och vid framställning av antikroppar
US4543252A (en) * 1982-01-21 1985-09-24 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4659692A (en) * 1982-11-19 1987-04-21 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4810777A (en) * 1987-03-04 1989-03-07 The United States Of America As Represented By The Department Of Health And Human Services Antimicrobial compounds
US5254535A (en) * 1989-04-17 1993-10-19 The Children's Hospital Of Pennsylvania Composition and treatment with biologically active peptides and antibiotic
US5045531A (en) * 1989-12-18 1991-09-03 Magainin Sciences Inc. Wound treatment employing biologically active ion channel forming peptides and proteins

Also Published As

Publication number Publication date
HU9202720D0 (en) 1992-12-28
EP0516747A4 (en) 1993-03-24
IE910630A1 (en) 1991-08-28
FI923747A0 (fi) 1992-08-20
NZ237202A (en) 1994-01-26
HUT63567A (en) 1993-09-28
IL97344A0 (en) 1992-05-25
EP0516747A1 (en) 1992-12-09
CN1054900A (zh) 1991-10-02
AU7485691A (en) 1991-09-18
JPH05506645A (ja) 1993-09-30
CA2076529A1 (en) 1991-08-24
FI923747A (fi) 1992-08-20
US5409898A (en) 1995-04-25
IL97344A (en) 1995-12-31
WO1991012815A1 (en) 1991-09-05
CZ47791A3 (en) 1993-04-14
AU650262B2 (en) 1994-06-16

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