OA06699A - Les éthers pharmaceutiques, leur préparation, leur utilisation et les produits intermédiaires pour ces éthers et leur préparation. - Google Patents

Les éthers pharmaceutiques, leur préparation, leur utilisation et les produits intermédiaires pour ces éthers et leur préparation.

Info

Publication number
OA06699A
OA06699A OA57193A OA57193A OA06699A OA 06699 A OA06699 A OA 06699A OA 57193 A OA57193 A OA 57193A OA 57193 A OA57193 A OA 57193A OA 06699 A OA06699 A OA 06699A
Authority
OA
OAPI
Prior art keywords
preparation
ethers
pharmaceutical
intermediates therefor
intermediates
Prior art date
Application number
OA57193A
Other languages
English (en)
French (fr)
Inventor
Kneen Geoffrey
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of OA06699A publication Critical patent/OA06699A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/30—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing —CHO groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/74—Unsaturated compounds containing —CHO groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
OA57193A 1979-06-29 1980-08-09 Les éthers pharmaceutiques, leur préparation, leur utilisation et les produits intermédiaires pour ces éthers et leur préparation. OA06699A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7922781 1979-06-29

Publications (1)

Publication Number Publication Date
OA06699A true OA06699A (fr) 1982-05-31

Family

ID=10506199

Family Applications (1)

Application Number Title Priority Date Filing Date
OA57193A OA06699A (fr) 1979-06-29 1980-08-09 Les éthers pharmaceutiques, leur préparation, leur utilisation et les produits intermédiaires pour ces éthers et leur préparation.

Country Status (18)

Country Link
US (1) US4410537A (en:Method)
EP (1) EP0022229B1 (en:Method)
JP (1) JPS5649335A (en:Method)
KR (2) KR850000073B1 (en:Method)
AU (1) AU545274B2 (en:Method)
DE (1) DE3061269D1 (en:Method)
DK (1) DK159770C (en:Method)
FI (1) FI71929C (en:Method)
GB (1) GB2053218B (en:Method)
GR (1) GR68748B (en:Method)
HU (1) HU190774B (en:Method)
IL (1) IL60422A (en:Method)
IT (1) IT1133025B (en:Method)
MW (1) MW2380A1 (en:Method)
OA (1) OA06699A (en:Method)
ZA (1) ZA803880B (en:Method)
ZM (1) ZM5780A1 (en:Method)
ZW (1) ZW14480A1 (en:Method)

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ZA818741B (en) * 1980-12-18 1983-07-27 Wellcome Found Pharmaceutical compounds,preparation,use and intermediates therefor and their preparation
GB8606913D0 (en) * 1986-03-20 1986-04-23 Hider R C Treatment of sickle cell disease
US6083522A (en) 1997-01-09 2000-07-04 Neucoll, Inc. Devices for tissue repair and methods for preparation and use thereof
US7279597B1 (en) 1999-11-05 2007-10-09 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
US7129274B1 (en) 1999-11-05 2006-10-31 Emisphere Technologies Inc. Phenoxy carboxylic acid compounds and compositions for delivering active agents
RU2300516C2 (ru) * 1999-11-05 2007-06-10 Эмисфере Текнолоджиз, Инк. Соединения феноксикарбоновой кислоты и композиции для доставки активных веществ
JP2004501057A (ja) * 1999-11-05 2004-01-15 エミスフェアー・テクノロジーズ・インク フェニルアミンカルボン酸化合物及び活性剤を送達するための組成物
US6649172B2 (en) 2000-03-17 2003-11-18 Corixa Corporation Amphipathic aldehydes and their uses as adjuvants and immunoeffectors
US8246969B2 (en) 2001-11-16 2012-08-21 Skinmedica, Inc. Compositions containing aromatic aldehydes and their use in treatments
KR101916489B1 (ko) 2011-01-07 2018-11-07 알러간, 인코포레이티드 멜라닌 변형 조성물들 및 이의 사용 방법들
PE20221914A1 (es) 2011-12-28 2022-12-23 Global Blood Therapeutics Inc Compuestos de benzaldehido sustituidos y metodos para su uso en incrementar la oxigenacion del tejido
ES2790358T3 (es) * 2011-12-28 2020-10-27 Global Blood Therapeutics Inc Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular
PE20161035A1 (es) * 2013-03-15 2016-11-13 Global Blood Therapeutics Inc Compuestos y usos de estos para la modulacion de la hemoglobina
BR112015021986A2 (pt) 2013-03-15 2017-07-18 Global Blood Therapeutics Inc compostos e seus usos para a modulação de hemoglobina
WO2014145040A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
AP2015008722A0 (en) 2013-03-15 2015-09-30 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
WO2015027067A2 (en) * 2013-08-23 2015-02-26 Virginia Commonwealth University Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease
EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
CN114181194A (zh) 2014-02-07 2022-03-15 全球血液疗法股份有限公司 一种化合物的结晶多晶型物
SG11201707127VA (en) 2015-03-06 2017-09-28 Beyondspring Pharmaceuticals Inc Method of treating cancer associated with a ras mutation
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
PT3383392T (pt) 2015-12-04 2025-09-01 Global Blood Therapeutics Inc Regimes de administração do 2-hidroxi-6-((2-(1-isopropil- 1h-pirazol-5-il)piridin-3-il)metoxi)benzaldeído
MY192703A (en) * 2016-02-08 2022-09-02 Beyondspring Pharmaceuticals Inc Compositions containing tucaresol or its analogs
AR108435A1 (es) 2016-05-12 2018-08-22 Global Blood Therapeutics Inc Proceso para sintetizar 2-hidroxi-6-((2-(1-isopropil-1h-pirazol-5-il)-piridin-3-il)metoxi)benzaldehído
BR112018074990A2 (pt) 2016-06-06 2019-03-12 Beyondspring Pharmaceuticals, Inc. composição, usos e método para reduzir neutropenia
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
CN110431135A (zh) 2017-01-06 2019-11-08 大连万春布林医药有限公司 微管蛋白结合化合物及其治疗用途
MX2019009020A (es) 2017-02-01 2019-11-12 Beyondspring Pharmaceuticals Inc Metodo para reducir la neutropenia.
US11401241B2 (en) * 2018-03-22 2022-08-02 Virginia Commonwealth University Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease
WO2020072377A1 (en) 2018-10-01 2020-04-09 Global Blood Therapeutics, Inc. Modulators of hemoglobin for the treatment of sickle cell disease
MA54231B1 (fr) 2018-11-19 2021-12-31 Global Blood Therapeutics Inc Composés de 2-formyl-3-hydroxyphényloxyméthyle capables de moduler l'hémoglobine
US12479816B2 (en) 2019-02-08 2025-11-25 University of Pittsburgh—of the Commonwealth System of Higher Education 20-HETE formation inhibitors
WO2022216908A1 (en) 2021-04-09 2022-10-13 Beyondspring Pharmaceuticals, Inc. Therapeutic compositions and methods for treating tumors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL236575A (en:Method) * 1958-04-30
CH543472A (fr) * 1969-01-31 1973-10-31 Orchimed Sa Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
CH550776A (de) 1971-03-05 1974-06-28 Ciba Geigy Ag Herstellung neuer bis-stilbenverbindungen.
DE2209128C3 (de) 1971-03-05 1981-10-22 CIBA-GEIGY AG, 4002 Basel Bis-Stilbenverbindungen, Verfahren zu deren Herstellung und deren Verwendung als optische Aufheller
GB1511645A (en) * 1974-05-31 1978-05-24 Univ Ife Sickle cell anaemia treatment
US4137309A (en) * 1976-10-14 1979-01-30 The Procter & Gamble Company Therapeutic treatment

Also Published As

Publication number Publication date
IT8049108A0 (it) 1980-06-27
EP0022229B1 (en) 1982-12-08
GB2053218B (en) 1984-01-25
KR840004668A (ko) 1984-10-22
HU190774B (en) 1986-11-28
DK159770C (da) 1991-04-22
IT1133025B (it) 1986-07-09
GR68748B (en:Method) 1982-02-16
GB2053218A (en) 1981-02-04
KR850000072B1 (ko) 1985-02-18
JPS5649335A (en) 1981-05-02
MW2380A1 (en) 1982-03-10
ZW14480A1 (en) 1982-03-17
FI71929B (fi) 1986-11-28
US4410537A (en) 1983-10-18
FI71929C (fi) 1987-03-09
DK279780A (da) 1980-12-30
FI802052A7 (fi) 1980-12-30
IL60422A0 (en) 1980-09-16
ZA803880B (en) 1982-02-24
EP0022229A1 (en) 1981-01-14
JPH0154339B2 (en:Method) 1989-11-17
KR830002693A (ko) 1983-05-30
AU545274B2 (en) 1985-07-11
AU5969780A (en) 1981-01-08
DK159770B (da) 1990-12-03
IL60422A (en) 1984-06-29
ZM5780A1 (en) 1983-11-21
DE3061269D1 (en) 1983-01-13
KR850000073B1 (ko) 1985-02-18

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