OA05506A - Nouvelles imidazo [1,2-a] pyridines substitués et leur procédé de préparation. - Google Patents

Nouvelles imidazo [1,2-a] pyridines substitués et leur procédé de préparation.

Info

Publication number
OA05506A
OA05506A OA56008A OA56008A OA05506A OA 05506 A OA05506 A OA 05506A OA 56008 A OA56008 A OA 56008A OA 56008 A OA56008 A OA 56008A OA 05506 A OA05506 A OA 05506A
Authority
OA
OAPI
Prior art keywords
pyridines
preparation process
new substituted
substituted imidazo
imidazo
Prior art date
Application number
OA56008A
Other languages
English (en)
French (fr)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of OA05506A publication Critical patent/OA05506A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86Hydrazides; Thio or imino analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
OA56008A 1975-12-09 1976-12-09 Nouvelles imidazo [1,2-a] pyridines substitués et leur procédé de préparation. OA05506A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63903475A 1975-12-09 1975-12-09

Publications (1)

Publication Number Publication Date
OA05506A true OA05506A (fr) 1981-04-30

Family

ID=24562456

Family Applications (1)

Application Number Title Priority Date Filing Date
OA56008A OA05506A (fr) 1975-12-09 1976-12-09 Nouvelles imidazo [1,2-a] pyridines substitués et leur procédé de préparation.

Country Status (25)

Country Link
US (1) US4096264A (US08197722-20120612-C00093.png)
JP (1) JPS5273896A (US08197722-20120612-C00093.png)
AR (1) AR222960A1 (US08197722-20120612-C00093.png)
AT (1) AT361475B (US08197722-20120612-C00093.png)
AU (1) AU505045B2 (US08197722-20120612-C00093.png)
BE (1) BE849123A (US08197722-20120612-C00093.png)
CA (1) CA1084930A (US08197722-20120612-C00093.png)
CH (1) CH626362A5 (US08197722-20120612-C00093.png)
DE (1) DE2655681A1 (US08197722-20120612-C00093.png)
DK (1) DK529276A (US08197722-20120612-C00093.png)
ES (1) ES453947A1 (US08197722-20120612-C00093.png)
FI (1) FI763343A (US08197722-20120612-C00093.png)
FR (1) FR2334357A1 (US08197722-20120612-C00093.png)
GB (1) GB1524589A (US08197722-20120612-C00093.png)
GR (1) GR62009B (US08197722-20120612-C00093.png)
IL (1) IL51024A (US08197722-20120612-C00093.png)
NL (1) NL7613160A (US08197722-20120612-C00093.png)
NO (1) NO764025L (US08197722-20120612-C00093.png)
NZ (1) NZ182756A (US08197722-20120612-C00093.png)
OA (1) OA05506A (US08197722-20120612-C00093.png)
PH (1) PH12259A (US08197722-20120612-C00093.png)
PL (1) PL103751B1 (US08197722-20120612-C00093.png)
PT (1) PT65915B (US08197722-20120612-C00093.png)
SE (1) SE430504B (US08197722-20120612-C00093.png)
ZA (1) ZA767331B (US08197722-20120612-C00093.png)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
US4154835A (en) * 1977-10-12 1979-05-15 Merck & Co., Inc. Anthelmintic imidazo [1,2-a] pyridines
US4250174A (en) * 1979-05-02 1981-02-10 Merck & Co., Inc. 3-Substituted imidazo [1,2-A] pyridines
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
US4507481A (en) * 1983-07-29 1985-03-26 Pennwalt Corporation Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines
IT1173196B (it) * 1984-02-02 1987-06-18 Bellon Roger Schoum Rbs Pharma Composti imidazopiridinici farmacologicamente attivi
US5214138A (en) * 1989-12-20 1993-05-25 Case Western Reserve University Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same
US5244908A (en) * 1990-07-30 1993-09-14 Takeda Chemical Industries, Ltd. Imidazopyridine derivatives and their pharmaceutical use
WO1999059587A1 (en) * 1998-05-20 1999-11-25 Eli Lilly And Company Anti-viral compounds
US6358971B1 (en) 1998-05-20 2002-03-19 Eli Lilly And Company Anti-viral compounds
DE10117184A1 (de) * 2001-04-05 2002-10-17 Gruenenthal Gmbh Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen
JP2007529496A (ja) * 2004-03-19 2007-10-25 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 抗菌剤としてのイミダゾピリジン及びイミダゾピリミジン誘導体
DE602005020313D1 (de) * 2004-08-12 2010-05-12 Amgen Inc Bisaryl-sulfonamide
US8304557B2 (en) * 2007-06-05 2012-11-06 Takeda Pharmaceutical Company Limited Fused heterocycle derivatives and use thereof
US8431608B2 (en) 2007-08-17 2013-04-30 Icagen Inc. Heterocycles as potassium channel modulators
US8058274B2 (en) * 2007-08-17 2011-11-15 Icagen, Inc. Heterocycles as potassium channel modulators
JP5270553B2 (ja) * 2007-08-23 2013-08-21 武田薬品工業株式会社 複素環化合物およびその用途
WO2009028629A1 (ja) * 2007-08-29 2009-03-05 Takeda Pharmaceutical Company Limited 複素環化合物およびその用途
EP2444403A1 (en) 2008-04-18 2012-04-25 Shionogi Co., Ltd. Heterocyclic compound having inhibitory activity on PI3K
US8445509B2 (en) * 2008-05-08 2013-05-21 Takeda Pharmaceutical Company Limited Fused heterocyclic derivatives and use thereof
EP2399921B1 (en) * 2008-12-01 2015-08-12 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
JO3101B1 (ar) 2008-12-02 2017-09-20 Takeda Pharmaceuticals Co مشتقات بنزوثيازول كعوامل مضادة للسرطان
US9567318B2 (en) 2009-08-17 2017-02-14 Memorial Sloan-Kettering Cancer Center Substituted pyrimidine compounds and uses thereof
KR102461419B1 (ko) 2014-05-13 2022-11-02 메모리얼 슬로안 케터링 캔서 센터 Hsp70 조정물질 및 이의 제조 및 이용 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3701780A (en) * 1970-09-18 1972-10-31 Merck & Co Inc Imidazo(1,2-a)pyridines
JPS5124517B1 (US08197722-20120612-C00093.png) * 1971-03-15 1976-07-24

Also Published As

Publication number Publication date
CA1084930A (en) 1980-09-02
US4096264A (en) 1978-06-20
DE2655681A1 (de) 1977-06-16
FR2334357B1 (US08197722-20120612-C00093.png) 1982-10-15
PL103751B1 (pl) 1979-07-31
JPS6126545B2 (US08197722-20120612-C00093.png) 1986-06-20
NZ182756A (en) 1979-11-01
BE849123A (fr) 1977-06-07
DK529276A (da) 1977-06-10
PT65915A (en) 1977-01-01
GB1524589A (en) 1978-09-13
PT65915B (en) 1978-11-07
ES453947A1 (es) 1978-03-01
GR62009B (en) 1979-02-15
NO764025L (US08197722-20120612-C00093.png) 1977-06-10
PH12259A (en) 1978-12-12
FR2334357A1 (fr) 1977-07-08
FI763343A (US08197722-20120612-C00093.png) 1977-06-10
AU505045B2 (en) 1979-11-08
IL51024A0 (en) 1977-01-31
JPS5273896A (en) 1977-06-21
CH626362A5 (US08197722-20120612-C00093.png) 1981-11-13
ATA901876A (de) 1980-08-15
AR222960A1 (es) 1981-07-15
AT361475B (de) 1981-03-10
SE7613128L (sv) 1977-06-10
NL7613160A (nl) 1977-06-13
ZA767331B (en) 1978-07-26
IL51024A (en) 1981-12-31
SE430504B (sv) 1983-11-21
AU2010276A (en) 1978-06-08

Similar Documents

Publication Publication Date Title
OA05506A (fr) Nouvelles imidazo [1,2-a] pyridines substitués et leur procédé de préparation.
BE847011A (fr) Pyrido (2,1-b) quinazolin-ones et leur procede de preparation
FR2315930A1 (fr) Derives de 1,4-dihydropyridine et leur procede de preparation
IL57541A0 (en) 7-oxo- -4-thia-2,6-diazabicyclo(3,2,0)heptene derivatives,process for their preparation and pharmaceutical compositons comprising the same
FR2319342A1 (fr) Nouvelles cyclobut-1-ene-3,4-diones substituees, leur procede de preparation et leur application
OA05403A (fr) Nouveaux dérivés de la thiazolo [3,4-b] isoquinoléine et leur procédé de préparation.
BE838079A (fr) Derives de tetrahydroisoquinoleine et leur procede de preparation
FR2301521A1 (fr) Nouvelles n-acyl-n-norsalutaridines et leur procede de preparation
FR2316239A1 (fr) Procede de preparation de 2,4-dioxo-1,2,3,4-tetrahydro-s-triazino-(1,2-a)-benzimidazoles
FR2321886A1 (fr) 3-phenylspiro-(isobenzofuranne-1,4'-piperidine)-sulfenamides, leur procede de preparation et leurs applications
FR2324301A1 (fr) Nouvelles pyrazolo(3,4-b)pyridyl-5 cetones et procede de leur preparation
BE863759A (fr) Nouvelles imidazo (1,5-b) pyridazines et procede pour leur preparation
BE843576A (fr) Derives de 1,4-dihydropyridine et leur procede de preparation
BE842687A (fr) Nouvelles thienyl-prostaglandines, leur procede de preparation et leur application
BE832791A (fr) Derives de pyrido(3,2-e)-as-triazine et procede pour leur preparation.
BE826926A (fr) Pyrrolo (3,4-b) pyridines et leur preparation
OA05349A (fr) Nouvelles énamines et leur procédé de préparation.
FR2309230A1 (fr) Derives de triazolocycloalkylthiadiazine et leur procede de preparation
FR2311537A1 (fr) Derives de 3-nitropyrazole et leur procede de preparation
BE849623A (fr) Pyrrolidones, leur procede de preparation et leur application
BE844158A (fr) Derives de 1,3-dihydro-3-phenyl-1'-(2-propynyl)spiro (isobenzofuranes),leur procede de preparation et leur application
FR2296424A1 (fr) Nouvelles triazolo(4,3-d)benzodiazepine-1,4 ones-6 et procedes de leur preparation
FR2303805A1 (fr) Benzimidazo(1,2-a)quinoleines et leur preparation
BE848366A (fr) Nocardicines e et f, et leur procede de preparation,
FR2297626A1 (fr) Hexahydro-1h-indeno (1,2-b) pyridines, leur procede de preparation et leurs applications