NZ754797A - Tianeptine oxalate salts and polymorphs - Google Patents
Tianeptine oxalate salts and polymorphsInfo
- Publication number
- NZ754797A NZ754797A NZ754797A NZ75479717A NZ754797A NZ 754797 A NZ754797 A NZ 754797A NZ 754797 A NZ754797 A NZ 754797A NZ 75479717 A NZ75479717 A NZ 75479717A NZ 754797 A NZ754797 A NZ 754797A
- Authority
- NZ
- New Zealand
- Prior art keywords
- tianeptine
- oxalate
- hemi
- mono
- disorder
- Prior art date
Links
- 229960005138 tianeptine Drugs 0.000 title claims abstract description 176
- -1 Tianeptine oxalate salts Chemical class 0.000 title claims description 8
- JICJBGPOMZQUBB-UHFFFAOYSA-N 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid Chemical compound O=S1(=O)N(C)C2=CC=CC=C2C(NCCCCCCC(O)=O)C2=CC=C(Cl)C=C21 JICJBGPOMZQUBB-UHFFFAOYSA-N 0.000 claims abstract description 171
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Classifications
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- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662439533P | 2016-12-28 | 2016-12-28 | |
| PCT/IB2017/001709 WO2018122606A1 (en) | 2016-12-28 | 2017-12-28 | Tianeptine oxalate salts and polymorphs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ754797A true NZ754797A (en) | 2022-05-27 |
Family
ID=61283255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ754797A NZ754797A (en) | 2016-12-28 | 2017-12-28 | Tianeptine oxalate salts and polymorphs |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10449203B2 (https=) |
| EP (1) | EP3562812A1 (https=) |
| JP (2) | JP2020503330A (https=) |
| CN (1) | CN110418785A (https=) |
| AU (1) | AU2017385958B2 (https=) |
| BR (1) | BR112019013244A2 (https=) |
| CA (1) | CA3048324A1 (https=) |
| IL (1) | IL267708A (https=) |
| MX (1) | MX2019007891A (https=) |
| MY (1) | MY199385A (https=) |
| NZ (1) | NZ754797A (https=) |
| WO (1) | WO2018122606A1 (https=) |
| ZA (1) | ZA201904185B (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10449203B2 (en) * | 2016-12-28 | 2019-10-22 | Tonix Pharma Holdings Limited | Tianeptine oxalate salts and polymorphs |
| US20240165126A1 (en) | 2021-03-15 | 2024-05-23 | Tonix Pharmaceuticals Holding Corp. | Tianeptine oxalate and naloxone combination for the treatment of major depressive disorder |
| EP4337638A1 (en) * | 2021-05-11 | 2024-03-20 | Astex Pharmaceuticals, Inc. | Solid forms of salts of 4-[5-[(3s)-3-aminopyrrolidine-1-carbonyl]-2-[2-fluoro-4-(2-hydroxy-2-ethylpropyl)phenyl]phenyl]-2-fluoro-benzonitrile |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US3758528A (en) * | 1970-03-13 | 1973-09-11 | Science Union & Cie | Tricyclic compounds |
| FR2635461B1 (fr) * | 1988-08-18 | 1992-01-17 | Adir | Utilisation de derives tricycliques pour l'obtention de medicaments destines au traitement du stress |
| US5405842A (en) | 1994-01-28 | 1995-04-11 | Silverman; Bernard A. | Treatment of steroid dependent asthmatics |
| FR2791891A1 (fr) | 1999-04-07 | 2000-10-13 | Adir | Utilisation de la tianeptine pour l'obtention de medicaments destines au traitement des pathologies de la neurodegenerescence |
| TW200517114A (en) | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| US9314469B2 (en) | 2008-05-05 | 2016-04-19 | Tonix Pharma Holdings Limited | Method for treating neurocognitive dysfunction |
| US8198268B2 (en) * | 2008-10-31 | 2012-06-12 | Janssen Biotech, Inc. | Tianeptine sulfate salt forms and methods of making and using the same |
| US10449203B2 (en) * | 2016-12-28 | 2019-10-22 | Tonix Pharma Holdings Limited | Tianeptine oxalate salts and polymorphs |
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2017
- 2017-12-28 US US15/856,818 patent/US10449203B2/en active Active
- 2017-12-28 EP EP17844642.3A patent/EP3562812A1/en not_active Withdrawn
- 2017-12-28 CA CA3048324A patent/CA3048324A1/en active Pending
- 2017-12-28 NZ NZ754797A patent/NZ754797A/en not_active IP Right Cessation
- 2017-12-28 AU AU2017385958A patent/AU2017385958B2/en not_active Ceased
- 2017-12-28 BR BR112019013244A patent/BR112019013244A2/pt not_active IP Right Cessation
- 2017-12-28 WO PCT/IB2017/001709 patent/WO2018122606A1/en not_active Ceased
- 2017-12-28 MY MYPI2019003711A patent/MY199385A/en unknown
- 2017-12-28 CN CN201780085697.9A patent/CN110418785A/zh active Pending
- 2017-12-28 MX MX2019007891A patent/MX2019007891A/es unknown
- 2017-12-28 JP JP2019535330A patent/JP2020503330A/ja active Pending
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2019
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- 2019-10-09 US US16/597,065 patent/US10946027B2/en active Active
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2022
- 2022-11-10 JP JP2022180549A patent/JP2023001340A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US10449203B2 (en) | 2019-10-22 |
| CN110418785A (zh) | 2019-11-05 |
| CA3048324A1 (en) | 2018-07-05 |
| MY199385A (en) | 2023-10-25 |
| ZA201904185B (en) | 2021-10-27 |
| WO2018122606A1 (en) | 2018-07-05 |
| BR112019013244A2 (pt) | 2019-12-24 |
| AU2017385958B2 (en) | 2021-12-02 |
| JP2020503330A (ja) | 2020-01-30 |
| JP2023001340A (ja) | 2023-01-04 |
| US20200276208A1 (en) | 2020-09-03 |
| MX2019007891A (es) | 2019-12-16 |
| US10946027B2 (en) | 2021-03-16 |
| IL267708A (en) | 2019-08-29 |
| AU2017385958A1 (en) | 2019-07-11 |
| EP3562812A1 (en) | 2019-11-06 |
| US20180338984A1 (en) | 2018-11-29 |
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