NZ724103A - Treatment of h. pylori infections using mtan inhibitors - Google Patents

Treatment of h. pylori infections using mtan inhibitors

Info

Publication number
NZ724103A
NZ724103A NZ724103A NZ72410315A NZ724103A NZ 724103 A NZ724103 A NZ 724103A NZ 724103 A NZ724103 A NZ 724103A NZ 72410315 A NZ72410315 A NZ 72410315A NZ 724103 A NZ724103 A NZ 724103A
Authority
NZ
New Zealand
Prior art keywords
treatment
pylori infections
inhibitors
mtan
mtan inhibitors
Prior art date
Application number
NZ724103A
Other languages
English (en)
Inventor
Keith Clinch
Vern Schramm
Shivali Gulab
Original Assignee
Albert Einstein College Medicine Inc
Victoria Link Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albert Einstein College Medicine Inc, Victoria Link Ltd filed Critical Albert Einstein College Medicine Inc
Publication of NZ724103A publication Critical patent/NZ724103A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ724103A 2014-02-12 2015-02-06 Treatment of h. pylori infections using mtan inhibitors NZ724103A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461938755P 2014-02-12 2014-02-12
PCT/US2015/014778 WO2015123101A1 (en) 2014-02-12 2015-02-06 Treatment of h. pylori infections using mtan inhibitors

Publications (1)

Publication Number Publication Date
NZ724103A true NZ724103A (en) 2020-07-31

Family

ID=53800544

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ724103A NZ724103A (en) 2014-02-12 2015-02-06 Treatment of h. pylori infections using mtan inhibitors

Country Status (12)

Country Link
US (2) US10118928B2 (enExample)
EP (1) EP3104707B1 (enExample)
JP (1) JP6512613B2 (enExample)
AU (1) AU2015217416B2 (enExample)
BR (1) BR112016019469B1 (enExample)
CA (1) CA2974916C (enExample)
HK (1) HK1232071A1 (enExample)
IL (1) IL247218B (enExample)
NZ (1) NZ724103A (enExample)
RU (1) RU2663803C2 (enExample)
SG (2) SG10201806381VA (enExample)
WO (1) WO2015123101A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6063571B2 (ja) 2012-08-07 2017-01-18 アルバート アインシュタイン カレッジ オブ メディシン,インコーポレイティド ヘリコバクター・ピロリ感染の治療
CN108794628A (zh) * 2018-05-28 2018-11-13 广东工业大学 一种抗幽门螺杆菌的卵黄抗体制备方法及应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985848A (en) 1997-10-14 1999-11-16 Albert Einstein College Of Medicine Of Yeshiva University Inhibitors of nucleoside metabolism
US7098334B2 (en) 2002-03-25 2006-08-29 Industrial Research Limited 4-amino-5H-pyrrolo[3,2-d]pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases
AU2003245442B2 (en) * 2002-06-13 2009-02-05 Vertex Pharmaceuticals Incorporated 2-ureido-6-heteroaryl-3h-benzoimidazole-4-carboxylic acid derivatives and related compounds as gyrase and/or topoisomerase IV inhibitors for the treatment of bacterial infections
US7553839B2 (en) 2002-08-21 2009-06-30 Industrial Research Limited 5h-pyrrolo[3,2-D] pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases
NZ533360A (en) 2004-06-04 2007-02-23 Ind Res Ltd Improved method for preparing 3-hydroxy-4-hydroxymethyl-pyrrolidine compounds
WO2007016291A2 (en) 2005-07-27 2007-02-08 Albert Einstein College Of Medicine Of Yeshiva University Transition state structure of 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidases
ES2362805T3 (es) 2006-09-07 2011-07-13 Industrial Research Limited Inhibidores aminoacíclicos de nucleósido fosforilasas e hidrolasas.
US8383636B2 (en) * 2006-09-07 2013-02-26 Industrial Research Limited Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase
DK2114925T3 (da) 2006-12-22 2012-05-29 Ind Res Ltd Azetidin-analoger af nucleosidase- og phosphorylase-inhibitorer
WO2008115531A1 (en) * 2007-03-21 2008-09-25 Novacea, Inc. Prevention and treatment of infectious conditions with active vitamin d compounds or mimics thereof
WO2010033236A2 (en) * 2008-09-22 2010-03-25 Albert Einstein College Of Medicine Of Yeshiva University Methods and compositions for treating bacterial infections by inhibiting quorum sensing
JP5861243B2 (ja) 2009-07-17 2016-02-16 アルバート アインシュタイン カレッジ オブ メディシン オブ イエシバ ユニバーシティ 5’−メチルチオアデノシンホスホリラーゼ及びヌクレオシダーゼの3−ヒドロキシピロリジン阻害剤
US9290501B2 (en) * 2010-11-29 2016-03-22 Albert Einstein College Of Medicine, Inc. Methods, assays and compounds for treating bacterial infections by inhibiting methylthioinosine phosphorylase
JP6063571B2 (ja) 2012-08-07 2017-01-18 アルバート アインシュタイン カレッジ オブ メディシン,インコーポレイティド ヘリコバクター・ピロリ感染の治療
US9522159B2 (en) 2012-09-11 2016-12-20 Albert Einstein College Of Medicine, Inc. Treatment and prevention of P. aeruginosa infections using coformycin analogs
WO2014073989A1 (en) 2012-11-12 2014-05-15 Callaghan Innovation Research Limited Salt and polymorphic forms of (3r,4s)-l-((4-amino-5h-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-4(methylthiomethyl)pyrodin-3-ol(mtdia)

Also Published As

Publication number Publication date
CA2974916A1 (en) 2015-08-20
AU2015217416B2 (en) 2018-10-04
WO2015123101A1 (en) 2015-08-20
RU2016136533A3 (enExample) 2018-06-06
JP2017506238A (ja) 2017-03-02
RU2663803C2 (ru) 2018-08-09
US10118928B2 (en) 2018-11-06
IL247218A0 (en) 2016-09-29
BR112016019469A2 (pt) 2018-07-24
SG10201806381VA (en) 2018-08-30
CA2974916C (en) 2022-05-31
US20190016730A1 (en) 2019-01-17
EP3104707A1 (en) 2016-12-21
AU2015217416A1 (en) 2016-09-29
US20170166571A1 (en) 2017-06-15
SG11201606595RA (en) 2016-09-29
EP3104707B1 (en) 2020-07-15
US10294233B2 (en) 2019-05-21
HK1232071A1 (zh) 2018-01-05
IL247218B (en) 2020-06-30
EP3104707A4 (en) 2017-12-13
BR112016019469B1 (pt) 2022-12-06
JP6512613B2 (ja) 2019-05-15
RU2016136533A (ru) 2018-03-13

Similar Documents

Publication Publication Date Title
IL264049A (en) Compounds, preparations and methods for treating the disease
IL264156A (en) Compounds, preparations and methods for treating the disease
ZA201700737B (en) Cyclohexyl-ethyl substituted diaza- and triaza-tricyclic compounds as indole-amine-2,3-dioxygenase (ido) antagonists for the treatment of cancer
IL254719A0 (en) Indoleamine 3,2-dioxygenase inhibitors for cancer treatment
ZA201704732B (en) Cyclic dinucleotides useful for the treatment of inter alia cancer
MX2020005213A (es) Inhibidores de proteina cinasa 2 activada por proteina cinasa activada por mitogeno (mk2) y sus usos.
ZA201606610B (en) Jak1 inhibitors for the treatment of myelodysplastic syndromes
AU2015299431B2 (en) Pyrrolidinone derivatives as metAP-2 inhibitors
LT3200815T (lt) Būdai ir kompozicijos, skirti vėžio gydymui
PL3634444T3 (pl) Kompozycje do zastosowania w leczeniu Helicobacter pylori
SG11201607791PA (en) Holding circuit, driving method of the holding circuit, and semiconductor device including the holding circuit
EA201790687A1 (ru) Хинолинкарбоксамиды для применения в лечении множественной миеломы
IL247218A0 (en) Treatment of infections caused by h. pylori using mtan inhibitors
SI3204486T1 (sl) Kompaktni reaktor za encimsko obdelavo
PL2926867T3 (pl) Kompozycje peelingujące zawierające kwas trichlorooctowy (TCA) i fenol do zmniejszania piekącego bólu wywołanego przez TCA
ZA201901948B (en) Heteroaryltrifluoroborate compounds for the treatment of mycobacterial infections
IL267059A (en) A preparation for the treatment of osteoarthritis
IL255167A0 (en) Compounds for the treatment of cancer
IL252237A0 (en) Compounds for the treatment of cancer
IN2014CH00872A (enExample)
PL409282A1 (pl) Związki hamujące oddziaływanie między białkami DnaA i HobA Helicobacter pylori oraz ich zastosowanie do leczenia lub zapobiegania zakażeniom H. pylori
UA103911U (ru) Средство с вазодилатирующей активностью
PT3204486T (pt) Reator compacto para tratamento enzimático
HK1226329A1 (en) Apilimod compositions and methods for using same

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 FEB 2022 BY COMPUTER PACKAGES INC

Effective date: 20210119

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 FEB 2023 BY COMPUTER PACKAGES INC

Effective date: 20220117

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 FEB 2024 BY COMPUTER PACKAGES INC

Effective date: 20230117

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 FEB 2025 BY COMPUTER PACKAGES INC

Effective date: 20240117

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 FEB 2026 BY COMPUTER PACKAGES INC

Effective date: 20250117