LT3200815T - Būdai ir kompozicijos, skirti vėžio gydymui - Google Patents
Būdai ir kompozicijos, skirti vėžio gydymuiInfo
- Publication number
- LT3200815T LT3200815T LTEP15847792.7T LT15847792T LT3200815T LT 3200815 T LT3200815 T LT 3200815T LT 15847792 T LT15847792 T LT 15847792T LT 3200815 T LT3200815 T LT 3200815T
- Authority
- LT
- Lithuania
- Prior art keywords
- compositions
- methods
- treating cancer
- cancer
- treating
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464402—Receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70517—CD8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/7056—Lectin superfamily, e.g. CD23, CD72
- C07K14/70564—Selectins, e.g. CD62
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/59—Reproductive system, e.g. uterus, ovaries, cervix or testes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462059068P | 2014-10-02 | 2014-10-02 | |
US201562202824P | 2015-08-08 | 2015-08-08 | |
PCT/US2015/053128 WO2016054153A1 (en) | 2014-10-02 | 2015-09-30 | Methods and compositions for treating cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
LT3200815T true LT3200815T (lt) | 2021-07-26 |
Family
ID=55631412
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP15847792.7T LT3200815T (lt) | 2014-10-02 | 2015-09-30 | Būdai ir kompozicijos, skirti vėžio gydymui |
Country Status (14)
Country | Link |
---|---|
US (3) | US10259855B2 (lt) |
EP (1) | EP3200815B1 (lt) |
CN (2) | CN106999552B (lt) |
CA (1) | CA2989807C (lt) |
DK (1) | DK3200815T3 (lt) |
ES (1) | ES2870607T3 (lt) |
HR (1) | HRP20210705T1 (lt) |
HU (1) | HUE054673T2 (lt) |
LT (1) | LT3200815T (lt) |
PL (1) | PL3200815T3 (lt) |
PT (1) | PT3200815T (lt) |
RS (1) | RS61929B1 (lt) |
SI (1) | SI3200815T1 (lt) |
WO (1) | WO2016054153A1 (lt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10538568B2 (en) * | 2014-11-04 | 2020-01-21 | The Trustees Of The University Of Pennsylvania | Methods and compositions of a follicle stimulating hormone receptor immunoreceptor |
CN108883181A (zh) * | 2016-04-05 | 2018-11-23 | 葛兰素史密斯克莱知识产权发展有限公司 | 在免疫疗法中抑制TGFβ |
JP7226803B2 (ja) * | 2016-10-11 | 2023-02-21 | オンコグリーン セラピューティクス エッセア | 腫瘍の診断及び治療におけるfshホルモン受容体のリガンド |
IT201600101870A1 (it) * | 2016-10-11 | 2018-04-11 | Abresearch Srl | Ligandi del recettore dell’ormone FSH nella diagnosi e nella terapia del neuroblastoma |
IT201600101852A1 (it) * | 2016-10-11 | 2018-04-11 | Abresearch Srl | Ligandi del recettore dell’ormone FSH nella diagnosi e nella terapia dei tumori |
WO2019070740A2 (en) * | 2017-10-02 | 2019-04-11 | Fred Hutchinson Cancer Research Center | LUTENING HORMONE RECEPTOR BINDING AGENTS AND LUTINISING HORMONE AGONISTS FOR IDENTIFICATION, MULTIPLICATION, REMOVAL AND MODIFICATION OF PRIMITIVE STEM CELL POPULATIONS |
WO2019136288A1 (en) * | 2018-01-05 | 2019-07-11 | Maxcyte, Inc. | Chronic car treatment for cancer |
AU2019375036A1 (en) * | 2018-11-05 | 2021-06-03 | Centre Hospitalier Universitaire Vaudois | Humanized and variant TGF-beta1 specific antibodies and methods and uses thereof |
US20220031747A1 (en) * | 2019-01-07 | 2022-02-03 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Foxp1-ablated chimeric cells |
US20220098324A1 (en) * | 2019-01-30 | 2022-03-31 | The Wistar Institute Of Anatomy And Biology | Dna-encoded bispecific t-cell engagers targeting cancer antigens and methods of use in cancer theraputics |
WO2021168421A1 (en) * | 2020-02-20 | 2021-08-26 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Method of enhancing immunotherapy using er stress pathway inhibitors |
US20240101626A1 (en) * | 2021-02-12 | 2024-03-28 | Kar Muthumani | Consensus prostate antigens, nucleic acid molecules encoding the same, and vaccines and uses comprising the same |
CN115975056B (zh) * | 2023-02-07 | 2023-12-01 | 徐州医科大学 | 利用天然蛋白tsh作为抗原结合位点构建靶向tshr的car-t细胞 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5702702A (en) | 1992-03-30 | 1997-12-30 | The Wistar Institute Of Anatomy And Biology | Modified cytotoxic tall cell line and compositions and methods for manufacture and use thereof as therapeutic reagents for cancer |
HU230364B1 (hu) | 2001-11-21 | 2016-03-29 | The Trustees Of The University Of Pennsylvania | Simian adenovírus nukleinsav és aminosav-szekvencia, azt tartalmazó vektorok, és eljárások annak alkalmazására |
US20060247420A1 (en) | 2002-09-04 | 2006-11-02 | George Coukos | Immune cell recptor ligand and immune cell receptor |
EP2000160A3 (en) | 2002-10-30 | 2009-03-11 | Gambro Lundia AB | Method and apparatuses for determining the efficiency of dialysis |
ES2871907T3 (es) | 2004-01-23 | 2021-11-02 | Msd Italia Srl | Portadores de vacuna de adenovirus de chimpancé |
US8076471B2 (en) | 2005-02-03 | 2011-12-13 | Benitec, Inc. | RNAi expression constructs |
GB0725201D0 (en) * | 2007-12-24 | 2008-01-30 | Asterion Ltd | Peptide fusion proteins |
DK2252627T3 (en) | 2008-01-24 | 2017-08-14 | Esperance Pharmaceuticals | MERGER CONSTRUCTION WITH LYTIC DOMAIN AND METHOD FOR PRODUCING AND USING SAME. |
EP2090322A1 (en) | 2008-02-18 | 2009-08-19 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of fsh receptor ligands for diagnosis and therapy of cancer |
BRPI0918122A8 (pt) * | 2008-12-19 | 2017-01-24 | Macrogenics Inc | molécula de diabody, diabody, e mólecula dart |
SG10201510092QA (en) | 2010-12-09 | 2016-01-28 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
US9708384B2 (en) | 2011-09-22 | 2017-07-18 | The Trustees Of The University Of Pennsylvania | Universal immune receptor expressed by T cells for the targeting of diverse and multiple antigens |
US9226936B2 (en) * | 2011-10-28 | 2016-01-05 | The Wistar of Anatomy and Biology | Methods and compositions for enhancing the therapeutic effect of anti-tumor T cells |
EP2920212A4 (en) * | 2012-11-15 | 2016-07-27 | Esperance Pharmaceuticals Inc | FUSION CONSTRUCTS FROM FOLLICULAR STIMULATING HORMONE (FSH) AND A LYTIC DOMAIN AND METHOD FOR THE PRODUCTION AND USE THEREOF |
CN103509121B (zh) * | 2012-11-22 | 2015-01-28 | 苏州康宁杰瑞生物科技有限公司 | 一种fsh融合蛋白及其制备方法和用途 |
US10538568B2 (en) | 2014-11-04 | 2020-01-21 | The Trustees Of The University Of Pennsylvania | Methods and compositions of a follicle stimulating hormone receptor immunoreceptor |
-
2015
- 2015-09-30 WO PCT/US2015/053128 patent/WO2016054153A1/en active Application Filing
- 2015-09-30 CN CN201580065382.9A patent/CN106999552B/zh active Active
- 2015-09-30 PT PT158477927T patent/PT3200815T/pt unknown
- 2015-09-30 LT LTEP15847792.7T patent/LT3200815T/lt unknown
- 2015-09-30 US US15/515,442 patent/US10259855B2/en active Active
- 2015-09-30 HU HUE15847792A patent/HUE054673T2/hu unknown
- 2015-09-30 ES ES15847792T patent/ES2870607T3/es active Active
- 2015-09-30 DK DK15847792.7T patent/DK3200815T3/da active
- 2015-09-30 PL PL15847792T patent/PL3200815T3/pl unknown
- 2015-09-30 RS RS20210553A patent/RS61929B1/sr unknown
- 2015-09-30 CN CN202111464043.1A patent/CN114150018A/zh active Pending
- 2015-09-30 CA CA2989807A patent/CA2989807C/en active Active
- 2015-09-30 SI SI201531592T patent/SI3200815T1/sl unknown
- 2015-09-30 EP EP15847792.7A patent/EP3200815B1/en active Active
-
2019
- 2019-02-21 US US16/281,472 patent/US11248033B2/en active Active
-
2021
- 2021-05-06 HR HRP20210705TT patent/HRP20210705T1/hr unknown
- 2021-12-27 US US17/562,643 patent/US20220185861A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN106999552A (zh) | 2017-08-01 |
PL3200815T3 (pl) | 2021-10-18 |
PT3200815T (pt) | 2021-05-07 |
US11248033B2 (en) | 2022-02-15 |
US20220185861A1 (en) | 2022-06-16 |
SI3200815T1 (sl) | 2021-11-30 |
ES2870607T3 (es) | 2021-10-27 |
CN114150018A (zh) | 2022-03-08 |
CA2989807C (en) | 2023-07-04 |
CA2989807A1 (en) | 2016-04-07 |
WO2016054153A1 (en) | 2016-04-07 |
HRP20210705T1 (hr) | 2021-07-23 |
RS61929B1 (sr) | 2021-06-30 |
DK3200815T3 (da) | 2021-05-10 |
US20170226176A1 (en) | 2017-08-10 |
EP3200815A4 (en) | 2018-04-25 |
EP3200815B1 (en) | 2021-03-03 |
EP3200815A1 (en) | 2017-08-09 |
US20190248862A1 (en) | 2019-08-15 |
CN106999552B (zh) | 2021-12-28 |
HUE054673T2 (hu) | 2021-09-28 |
US10259855B2 (en) | 2019-04-16 |
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