IL247218B - Treatment of infections caused by h. pylori using mtan inhibitors - Google Patents
Treatment of infections caused by h. pylori using mtan inhibitorsInfo
- Publication number
- IL247218B IL247218B IL247218A IL24721816A IL247218B IL 247218 B IL247218 B IL 247218B IL 247218 A IL247218 A IL 247218A IL 24721816 A IL24721816 A IL 24721816A IL 247218 B IL247218 B IL 247218B
- Authority
- IL
- Israel
- Prior art keywords
- treatment
- pylori infections
- mtan inhibitors
- mtan
- inhibitors
- Prior art date
Links
- 208000015181 infectious disease Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461938755P | 2014-02-12 | 2014-02-12 | |
| PCT/US2015/014778 WO2015123101A1 (en) | 2014-02-12 | 2015-02-06 | Treatment of h. pylori infections using mtan inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL247218A0 IL247218A0 (en) | 2016-09-29 |
| IL247218B true IL247218B (en) | 2020-06-30 |
Family
ID=53800544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL247218A IL247218B (en) | 2014-02-12 | 2016-08-10 | Treatment of infections caused by h. pylori using mtan inhibitors |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10118928B2 (enExample) |
| EP (1) | EP3104707B1 (enExample) |
| JP (1) | JP6512613B2 (enExample) |
| AU (1) | AU2015217416B2 (enExample) |
| BR (1) | BR112016019469B1 (enExample) |
| CA (1) | CA2974916C (enExample) |
| HK (1) | HK1232071A1 (enExample) |
| IL (1) | IL247218B (enExample) |
| NZ (1) | NZ724103A (enExample) |
| RU (1) | RU2663803C2 (enExample) |
| SG (2) | SG10201806381VA (enExample) |
| WO (1) | WO2015123101A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6063571B2 (ja) | 2012-08-07 | 2017-01-18 | アルバート アインシュタイン カレッジ オブ メディシン，インコーポレイティド | ヘリコバクター・ピロリ感染の治療 |
| CN108794628A (zh) * | 2018-05-28 | 2018-11-13 | 广东工业大学 | 一种抗幽门螺杆菌的卵黄抗体制备方法及应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985848A (en) | 1997-10-14 | 1999-11-16 | Albert Einstein College Of Medicine Of Yeshiva University | Inhibitors of nucleoside metabolism |
| US7098334B2 (en) | 2002-03-25 | 2006-08-29 | Industrial Research Limited | 4-amino-5H-pyrrolo[3,2-d]pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases |
| AU2003245442B2 (en) * | 2002-06-13 | 2009-02-05 | Vertex Pharmaceuticals Incorporated | 2-ureido-6-heteroaryl-3h-benzoimidazole-4-carboxylic acid derivatives and related compounds as gyrase and/or topoisomerase IV inhibitors for the treatment of bacterial infections |
| US7553839B2 (en) | 2002-08-21 | 2009-06-30 | Industrial Research Limited | 5h-pyrrolo[3,2-D] pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases |
| NZ533360A (en) | 2004-06-04 | 2007-02-23 | Ind Res Ltd | Improved method for preparing 3-hydroxy-4-hydroxymethyl-pyrrolidine compounds |
| WO2007016291A2 (en) | 2005-07-27 | 2007-02-08 | Albert Einstein College Of Medicine Of Yeshiva University | Transition state structure of 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidases |
| ES2362805T3 (es) | 2006-09-07 | 2011-07-13 | Industrial Research Limited | Inhibidores aminoacíclicos de nucleósido fosforilasas e hidrolasas. |
| US8383636B2 (en) * | 2006-09-07 | 2013-02-26 | Industrial Research Limited | Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase |
| DK2114925T3 (da) | 2006-12-22 | 2012-05-29 | Ind Res Ltd | Azetidin-analoger af nucleosidase- og phosphorylase-inhibitorer |
| WO2008115531A1 (en) * | 2007-03-21 | 2008-09-25 | Novacea, Inc. | Prevention and treatment of infectious conditions with active vitamin d compounds or mimics thereof |
| WO2010033236A2 (en) * | 2008-09-22 | 2010-03-25 | Albert Einstein College Of Medicine Of Yeshiva University | Methods and compositions for treating bacterial infections by inhibiting quorum sensing |
| JP5861243B2 (ja) | 2009-07-17 | 2016-02-16 | アルバート アインシュタイン カレッジ オブ メディシン オブ イエシバ ユニバーシティ | ５’−メチルチオアデノシンホスホリラーゼ及びヌクレオシダーゼの３−ヒドロキシピロリジン阻害剤 |
| US9290501B2 (en) * | 2010-11-29 | 2016-03-22 | Albert Einstein College Of Medicine, Inc. | Methods, assays and compounds for treating bacterial infections by inhibiting methylthioinosine phosphorylase |
| JP6063571B2 (ja) | 2012-08-07 | 2017-01-18 | アルバート アインシュタイン カレッジ オブ メディシン，インコーポレイティド | ヘリコバクター・ピロリ感染の治療 |
| US9522159B2 (en) | 2012-09-11 | 2016-12-20 | Albert Einstein College Of Medicine, Inc. | Treatment and prevention of P. aeruginosa infections using coformycin analogs |
| WO2014073989A1 (en) | 2012-11-12 | 2014-05-15 | Callaghan Innovation Research Limited | Salt and polymorphic forms of (3r,4s)-l-((4-amino-5h-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-4(methylthiomethyl)pyrodin-3-ol(mtdia) |
-
2015
- 2015-02-06 EP EP15748925.3A patent/EP3104707B1/en active Active
- 2015-02-06 WO PCT/US2015/014778 patent/WO2015123101A1/en not_active Ceased
- 2015-02-06 RU RU2016136533A patent/RU2663803C2/ru active
- 2015-02-06 BR BR112016019469-1A patent/BR112016019469B1/pt active IP Right Grant
- 2015-02-06 SG SG10201806381VA patent/SG10201806381VA/en unknown
- 2015-02-06 JP JP2016552328A patent/JP6512613B2/ja active Active
- 2015-02-06 US US15/118,113 patent/US10118928B2/en active Active
- 2015-02-06 AU AU2015217416A patent/AU2015217416B2/en active Active
- 2015-02-06 NZ NZ724103A patent/NZ724103A/en unknown
- 2015-02-06 SG SG11201606595RA patent/SG11201606595RA/en unknown
- 2015-02-06 CA CA2974916A patent/CA2974916C/en active Active
- 2015-02-06 HK HK17105755.5A patent/HK1232071A1/zh unknown
-
2016
- 2016-08-10 IL IL247218A patent/IL247218B/en active IP Right Grant
-
2018
- 2018-09-20 US US16/136,314 patent/US10294233B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2974916A1 (en) | 2015-08-20 |
| AU2015217416B2 (en) | 2018-10-04 |
| WO2015123101A1 (en) | 2015-08-20 |
| RU2016136533A3 (enExample) | 2018-06-06 |
| JP2017506238A (ja) | 2017-03-02 |
| RU2663803C2 (ru) | 2018-08-09 |
| US10118928B2 (en) | 2018-11-06 |
| IL247218A0 (en) | 2016-09-29 |
| NZ724103A (en) | 2020-07-31 |
| BR112016019469A2 (pt) | 2018-07-24 |
| SG10201806381VA (en) | 2018-08-30 |
| CA2974916C (en) | 2022-05-31 |
| US20190016730A1 (en) | 2019-01-17 |
| EP3104707A1 (en) | 2016-12-21 |
| AU2015217416A1 (en) | 2016-09-29 |
| US20170166571A1 (en) | 2017-06-15 |
| SG11201606595RA (en) | 2016-09-29 |
| EP3104707B1 (en) | 2020-07-15 |
| US10294233B2 (en) | 2019-05-21 |
| HK1232071A1 (zh) | 2018-01-05 |
| EP3104707A4 (en) | 2017-12-13 |
| BR112016019469B1 (pt) | 2022-12-06 |
| JP6512613B2 (ja) | 2019-05-15 |
| RU2016136533A (ru) | 2018-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |