NZ700340A - Lentiviral vector particles having improved transduction efficiency for cells expressing dc- sign - Google Patents
Lentiviral vector particles having improved transduction efficiency for cells expressing dc- signInfo
- Publication number
- NZ700340A NZ700340A NZ700340A NZ70034013A NZ700340A NZ 700340 A NZ700340 A NZ 700340A NZ 700340 A NZ700340 A NZ 700340A NZ 70034013 A NZ70034013 A NZ 70034013A NZ 700340 A NZ700340 A NZ 700340A
- Authority
- NZ
- New Zealand
- Prior art keywords
- lentiviral vector
- cells expressing
- sign
- vector particles
- transduction efficiency
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 3
- 108010037897 DC-specific ICAM-3 grabbing nonintegrin Proteins 0.000 title abstract 2
- 230000026683 transduction Effects 0.000 title 1
- 238000010361 transduction Methods 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 3
- 239000002157 polynucleotide Substances 0.000 abstract 3
- 210000004443 dendritic cell Anatomy 0.000 abstract 2
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- YINZYTTZHLPWBO-UHFFFAOYSA-N Kifunensine Natural products COC1C(O)C(O)C(O)C2NC(=O)C(=O)N12 YINZYTTZHLPWBO-UHFFFAOYSA-N 0.000 abstract 1
- 101710149136 Protein Vpr Proteins 0.000 abstract 1
- 102000047164 SAM Domain and HD Domain-Containing Protein 1 Human genes 0.000 abstract 1
- 108700019718 SAM Domain and HD Domain-Containing Protein 1 Proteins 0.000 abstract 1
- 101150114242 SAMHD1 gene Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- OIURYJWYVIAOCW-VFUOTHLCSA-N kifunensine Chemical compound OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2NC(=O)C(=O)N12 OIURYJWYVIAOCW-VFUOTHLCSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
Classifications
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Applications Claiming Priority (5)
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| US13/436,472 US8323662B1 (en) | 2012-03-30 | 2012-03-30 | Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein |
| US201261666103P | 2012-06-29 | 2012-06-29 | |
| US201261732756P | 2012-12-03 | 2012-12-03 | |
| US201361789575P | 2013-03-15 | 2013-03-15 | |
| PCT/US2013/034640 WO2013149167A1 (en) | 2012-03-30 | 2013-03-29 | Lentiviral vector particles having improved transduction efficiency for cells expressing dc- sign |
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| EP3480316A1 (en) | 2019-05-08 |
| EP2831095B1 (en) | 2018-11-28 |
| EA201491813A1 (ru) | 2015-08-31 |
| CN104583231B (zh) | 2021-02-26 |
| EP2831095A1 (en) | 2015-02-04 |
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