NZ612063A - Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration - Google Patents

Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration

Info

Publication number
NZ612063A
NZ612063A NZ612063A NZ61206310A NZ612063A NZ 612063 A NZ612063 A NZ 612063A NZ 612063 A NZ612063 A NZ 612063A NZ 61206310 A NZ61206310 A NZ 61206310A NZ 612063 A NZ612063 A NZ 612063A
Authority
NZ
New Zealand
Prior art keywords
vasoconstrictor
tetracaine
medicament
intranasal administration
nasal
Prior art date
Application number
NZ612063A
Other languages
English (en)
Inventor
Mark David Kollar
Original Assignee
St Renatus Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Renatus Llc filed Critical St Renatus Llc
Publication of NZ612063A publication Critical patent/NZ612063A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M19/00—Local anaesthesia; Hypothermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ612063A 2009-04-03 2010-04-02 Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration NZ612063A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16668009P 2009-04-03 2009-04-03
NZ595376A NZ595376A (en) 2009-04-03 2010-04-02 Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration

Publications (1)

Publication Number Publication Date
NZ612063A true NZ612063A (en) 2015-02-27

Family

ID=42164462

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ612063A NZ612063A (en) 2009-04-03 2010-04-02 Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration
NZ595376A NZ595376A (en) 2009-04-03 2010-04-02 Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ595376A NZ595376A (en) 2009-04-03 2010-04-02 Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration

Country Status (18)

Country Link
US (7) US8580282B2 (https=)
EP (1) EP2413899B1 (https=)
JP (3) JP5788864B2 (https=)
KR (2) KR20170026639A (https=)
CN (2) CN102421416B (https=)
AU (2) AU2010232995C1 (https=)
BR (1) BRPI1010303A2 (https=)
CA (1) CA2757032C (https=)
DK (1) DK2413899T3 (https=)
EA (1) EA024184B1 (https=)
ES (1) ES2861064T3 (https=)
IL (1) IL215489A0 (https=)
MX (1) MX2011010445A (https=)
NZ (2) NZ612063A (https=)
PL (1) PL2413899T3 (https=)
PT (1) PT2413899T (https=)
WO (1) WO2010114622A1 (https=)
ZA (2) ZA201107011B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170026639A (ko) 2009-04-03 2017-03-08 세인트 레나투스, 엘엘씨 비강 투여를 위한 테트라카인 및 혈관수축제를 포함하는 치과용 마취제
EP2903604A1 (en) * 2012-09-28 2015-08-12 St. Renatus, LLC Pharmaceutical composition comprising benzyl alcohol for the treatment of migraines
US20180193462A1 (en) * 2014-01-01 2018-07-12 Real Time Imaging Technologies, Llc Improved local anesthetic solution for dental and/or contrast media use
AU2015277272A1 (en) * 2014-06-16 2017-01-12 Loewi LLC Methods of anesthetizing nerve tissue in the trigeminal nerve pathway and medical uses thereof
CN107249568A (zh) * 2014-12-23 2017-10-13 圣雷纳图斯有限责任公司 基于丁卡因的麻醉药
EP3244800A1 (en) 2015-01-12 2017-11-22 Real Time Imaging Technologies, LLC Low-dose x-ray imaging system
US10039830B2 (en) * 2016-03-04 2018-08-07 Cetylite Industries, Inc. Topical anesthetic composition
US20170360718A1 (en) * 2016-06-01 2017-12-21 St. Renatus, Llc Intranasal dental anesthetic
EP3897603A4 (en) 2018-12-19 2022-09-14 Grace Therapeutics Inc. THERAPEUTIC COMPOSITION OF INTRANASAL LIDOCAINE
CN111494310A (zh) * 2020-04-29 2020-08-07 周晓玲 一种局部麻醉药物的制备及使用方法
WO2024151854A1 (en) * 2023-01-13 2024-07-18 Smilanich Michael D Composition for local anesthesia and uses thereof
GB2628149A (en) * 2023-03-16 2024-09-18 Lee Nathaniel Wurie Nasal spray for performing sphenopalatine ganglion block

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3832460A (en) * 1971-03-19 1974-08-27 C Kosti Anesthetic-vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue
US5209724A (en) 1988-04-11 1993-05-11 Dhaliwal Avtar S Composite anesthetic article and method of use
AU4673993A (en) 1992-07-28 1994-02-14 Procter & Gamble Company, The Pharmaceutical composition for topical use containing a crosslinked cationic polymer and an alkoxylated ether
WO1995013810A1 (en) 1993-11-19 1995-05-26 Schering-Plough Healthcare Products Incorporated Nasal spray compositions containing oxymetazoline
US5585398A (en) * 1994-07-15 1996-12-17 Ernst; Amy A. Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use
US6075059A (en) 1999-02-24 2000-06-13 The Ohio State University Compositions for dental anesthesia
US20040131665A1 (en) * 1999-10-22 2004-07-08 Wepfer Scott T. Topical anesthetic formulation
US6413499B1 (en) * 2000-01-06 2002-07-02 Bryan M. Clay Methods and kits for maxillary dental anesthesia by means of a nasal deliverable anesthetic
US20040045546A1 (en) 2002-09-05 2004-03-11 Peirce Management, Llc Pharmaceutical delivery system for oral inhalation through nebulization consisting of inert substrate impregnated with substance (S) to be solubilized or suspended prior to use
JP4591746B2 (ja) 2002-12-03 2010-12-01 大正製薬株式会社 難溶性抗ウイルス成分含有水溶性外用剤組成物
ES2223277B1 (es) * 2003-06-19 2006-03-01 Fernando Bouffard Fita Composicion anestesica para administracion topica.
EA009669B1 (ru) 2004-01-01 2008-02-28 Панацея Биотек Лтд. Фармацевтические композиции, содержащие экстракт euphorbia prostrata
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
US20070154402A1 (en) 2005-10-24 2007-07-05 Collegium Pharmaceutical, Inc. Topical Pharmaceutical Foam Composition
US9252862B2 (en) 2008-09-17 2016-02-02 Qualcomm Incorporated MIMO preamble for initial access with an unknown number of transmit antennas
KR20170026639A (ko) * 2009-04-03 2017-03-08 세인트 레나투스, 엘엘씨 비강 투여를 위한 테트라카인 및 혈관수축제를 포함하는 치과용 마취제

Also Published As

Publication number Publication date
CN103932973A (zh) 2014-07-23
CA2757032A1 (en) 2010-10-07
US8580282B2 (en) 2013-11-12
CN102421416B (zh) 2014-05-28
US9308191B2 (en) 2016-04-12
CA2757032C (en) 2022-06-07
JP5788864B2 (ja) 2015-10-07
EA024184B1 (ru) 2016-08-31
JP2012522783A (ja) 2012-09-27
EP2413899B1 (en) 2021-01-27
US20170326112A1 (en) 2017-11-16
JP2017031226A (ja) 2017-02-09
US10456377B2 (en) 2019-10-29
US10420750B2 (en) 2019-09-24
CN103932973B (zh) 2017-08-11
AU2010232995A1 (en) 2011-10-20
KR20120042729A (ko) 2012-05-03
NZ595376A (en) 2013-09-27
KR20170026639A (ko) 2017-03-08
ZA201309321B (en) 2016-07-27
CN102421416A (zh) 2012-04-18
ES2861064T3 (es) 2021-10-05
AU2015242984B2 (en) 2017-09-14
US20120039960A1 (en) 2012-02-16
JP2015034167A (ja) 2015-02-19
IL215489A0 (en) 2011-12-29
US9855247B2 (en) 2018-01-02
PL2413899T3 (pl) 2021-09-20
AU2015242984A1 (en) 2015-11-05
US20170326111A1 (en) 2017-11-16
EA201171215A1 (ru) 2012-07-30
PT2413899T (pt) 2021-03-30
US20170319547A1 (en) 2017-11-09
US20160184269A1 (en) 2016-06-30
WO2010114622A1 (en) 2010-10-07
US20200268715A1 (en) 2020-08-27
US20140234421A1 (en) 2014-08-21
DK2413899T3 (da) 2021-04-19
KR101747979B1 (ko) 2017-06-15
ZA201107011B (en) 2014-03-26
BRPI1010303A2 (pt) 2016-03-15
AU2010232995C1 (en) 2016-01-28
EP2413899A1 (en) 2012-02-08
AU2010232995B2 (en) 2015-07-16
MX2011010445A (es) 2012-01-19

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