NZ599291A - Antimicrobial compounds and methods of making and using the same - Google Patents

Antimicrobial compounds and methods of making and using the same

Info

Publication number
NZ599291A
NZ599291A NZ599291A NZ59929110A NZ599291A NZ 599291 A NZ599291 A NZ 599291A NZ 599291 A NZ599291 A NZ 599291A NZ 59929110 A NZ59929110 A NZ 59929110A NZ 599291 A NZ599291 A NZ 599291A
Authority
NZ
New Zealand
Prior art keywords
making
methods
antimicrobial compounds
same
compounds
Prior art date
Application number
NZ599291A
Other languages
English (en)
Inventor
Erin M Duffy
Ashoke Bhattacharjee
Hardwin O’Dowd
Marco Devivo
Zoltan F Kanyo
Jacek G Martinow
Ik-Hyeon Paik
Matthew H Scheideman
Sandra Sinishtaj
Brian T Wimberly
Yusheng Wu
Original Assignee
Melinta Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melinta Therapeutics Inc filed Critical Melinta Therapeutics Inc
Publication of NZ599291A publication Critical patent/NZ599291A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Materials For Medical Uses (AREA)
NZ599291A 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same NZ599291A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25247809P 2009-10-16 2009-10-16
US31428710P 2010-03-16 2010-03-16
US35820110P 2010-06-24 2010-06-24
PCT/US2010/052922 WO2011047319A2 (en) 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same

Publications (1)

Publication Number Publication Date
NZ599291A true NZ599291A (en) 2014-06-27

Family

ID=44343888

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ599291A NZ599291A (en) 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same

Country Status (15)

Country Link
US (2) US9193731B2 (https=)
EP (2) EP3406613A1 (https=)
JP (1) JP6267863B2 (https=)
KR (2) KR101972992B1 (https=)
CN (1) CN102712647B (https=)
AU (3) AU2010306646B2 (https=)
CA (1) CA2777734A1 (https=)
DK (1) DK2488525T3 (https=)
EA (1) EA201270566A1 (https=)
ES (1) ES2675798T3 (https=)
IL (2) IL219133A (https=)
MX (2) MX349718B (https=)
NZ (1) NZ599291A (https=)
PH (1) PH12016502092A1 (https=)
WO (1) WO2011047319A2 (https=)

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EP3038623A4 (en) 2013-09-09 2017-04-19 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
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CA2979342A1 (en) * 2015-03-11 2016-09-15 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
WO2017070089A1 (en) 2015-10-19 2017-04-27 Incyte Corporation Heterocyclic compounds as immunomodulators
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MA44075A (fr) 2015-12-17 2021-05-19 Incyte Corp Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1
AU2016379372A1 (en) 2015-12-22 2018-08-02 Incyte Corporation Heterocyclic compounds as immunomodulators
WO2017193016A1 (en) 2016-05-06 2017-11-09 Melinta Therapeutics, Inc. Antimicrobials and methods of making and using same
MX2018013545A (es) 2016-05-06 2019-08-14 Melinta Therapeutics Inc Antimicrobianos y metodos de preparacion y uso de los mismos.
US10934295B2 (en) * 2016-05-06 2021-03-02 BioVersys AG Antimicrobials and methods of making and using same
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JP7101678B2 (ja) 2016-12-22 2022-07-15 インサイト・コーポレイション 免疫調節剤としての複素環式化合物
US20180179202A1 (en) 2016-12-22 2018-06-28 Incyte Corporation Heterocyclic compounds as immunomodulators
AU2018288665A1 (en) 2017-06-19 2019-12-19 Ashoke Bhattacharjee Antimicrobials and methods of making and using same
US20210403473A1 (en) * 2018-02-21 2021-12-30 BioVersys AG Antimicrobial compounds and methods of making and using the same
SMT202500157T1 (it) 2018-03-30 2025-05-12 Incyte Corp Composti eterociclici come immunomodulatori
HUE061503T2 (hu) 2018-05-11 2023-07-28 Incyte Corp Tetrahidro-imidazo[4,5-C]piridin-származékok mint PD-L1 immunmodulátorok
US12152031B2 (en) 2018-06-06 2024-11-26 BioVersys AG Biodefense agents
WO2019234509A2 (en) 2018-06-06 2019-12-12 BioVersys AG Aminomethylamidine and methylamidine antimicrobial compounds
MA52873A (fr) * 2018-06-15 2021-04-21 Galapagos Nv Nouveaux composés et compositions pharmaceutiques associées pour le traitement de maladies
US20240239800A1 (en) * 2018-12-07 2024-07-18 BioVersys AG Pyrrolo[2,3-d]pyrimidin-2-one antimicrobial compounds
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Also Published As

Publication number Publication date
ES2675798T3 (es) 2018-07-12
US20120220566A1 (en) 2012-08-30
MX2012004340A (es) 2012-11-23
IL219133A0 (en) 2012-06-28
AU2016266048B2 (en) 2018-07-19
JP2013508297A (ja) 2013-03-07
WO2011047319A8 (en) 2011-10-27
JP6267863B2 (ja) 2018-01-24
PH12016502092A1 (en) 2017-08-30
CA2777734A1 (en) 2011-04-21
IL255097A0 (en) 2017-12-31
IL219133A (en) 2017-10-31
CN102712647A (zh) 2012-10-03
US20160031893A1 (en) 2016-02-04
KR101972992B1 (ko) 2019-04-29
WO2011047319A3 (en) 2011-08-18
KR20170132900A (ko) 2017-12-04
DK2488525T3 (en) 2018-08-06
WO2011047319A2 (en) 2011-04-21
AU2018204628A1 (en) 2018-07-12
AU2010306646B2 (en) 2016-09-01
EP3406613A1 (en) 2018-11-28
AU2010306646A1 (en) 2012-05-03
AU2016266048A1 (en) 2016-12-22
KR20190044136A (ko) 2019-04-29
US9193731B2 (en) 2015-11-24
EP2488525B1 (en) 2018-04-25
EP2488525A2 (en) 2012-08-22
EA201270566A1 (ru) 2012-11-30
EP2488525A4 (en) 2013-07-03
CN102712647B (zh) 2018-04-24
MX349718B (es) 2017-08-10

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