NZ596614A - Diagnosis and treatment of alzheimer's disease - Google Patents
Diagnosis and treatment of alzheimer's diseaseInfo
- Publication number
- NZ596614A NZ596614A NZ59661410A NZ59661410A NZ596614A NZ 596614 A NZ596614 A NZ 596614A NZ 59661410 A NZ59661410 A NZ 59661410A NZ 59661410 A NZ59661410 A NZ 59661410A NZ 596614 A NZ596614 A NZ 596614A
- Authority
- NZ
- New Zealand
- Prior art keywords
- alzheimer
- disease
- diagnosis
- treatment
- snps
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0911539A GB0911539D0 (en) | 2009-07-03 | 2009-07-03 | Diagnosis of alzheimer's disease |
| GB0913357A GB0913357D0 (en) | 2009-07-31 | 2009-07-31 | Diagnosis of alzheimer's disease |
| GB0917326A GB0917326D0 (en) | 2009-10-03 | 2009-10-03 | Diagnosis of alzheimer's disease |
| PCT/GB2010/001208 WO2011001135A2 (en) | 2009-07-03 | 2010-06-22 | Diagnosis and treatment of alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ596614A true NZ596614A (en) | 2012-11-30 |
Family
ID=43014386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ59661410A NZ596614A (en) | 2009-07-03 | 2010-06-22 | Diagnosis and treatment of alzheimer's disease |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20120122703A1 (https=) |
| EP (2) | EP2891723B1 (https=) |
| JP (2) | JP5917395B2 (https=) |
| CN (2) | CN102471800A (https=) |
| AU (1) | AU2010267835C1 (https=) |
| CA (1) | CA2766876C (https=) |
| NZ (1) | NZ596614A (https=) |
| WO (1) | WO2011001135A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2766876C (en) * | 2009-07-03 | 2020-01-28 | University College Cardiff Consultants Limited | Variants of clu/apoj, picalm, abca7, cr1 and bin1 gene loci and the ms4a gene cluster for the diagnosis of alzheimer's disease |
| WO2011024035A1 (en) * | 2009-08-27 | 2011-03-03 | Institut Pasteur De Lille | Method for determining the risk of occurrence of alzheimer's disease |
| GB201212334D0 (en) * | 2012-07-11 | 2012-08-22 | Warwick The | Therapeutic targets for alzheimers disease |
| CN104102839B (zh) * | 2013-11-16 | 2017-10-27 | 西安电子科技大学 | 一种基于多尺度网格曲面形状特征的阿尔茨海默病脑皮层自动分类方法 |
| CN105969885A (zh) * | 2016-06-24 | 2016-09-28 | 江苏雄鸣医药科技有限公司 | 一种阿尔兹海默症的基因诊断试剂盒 |
| CN106978475A (zh) * | 2016-08-17 | 2017-07-25 | 上海易瑞生物科技有限公司 | 一种阿尔茨海默氏病易感基因检测分型试剂盒及其应用 |
| CN106290823A (zh) * | 2016-10-18 | 2017-01-04 | 上海凯璟生物科技有限公司 | 一种阿尔兹海默综合症标志物abca7检测试剂盒和制备方法 |
| US11725232B2 (en) * | 2016-10-31 | 2023-08-15 | The Hong Kong University Of Science And Technology | Compositions, methods and kits for detection of genetic variants for alzheimer's disease |
| US20210293794A1 (en) * | 2017-02-24 | 2021-09-23 | University Of Hawii Cancer Center | Metabolic biomarkers for the identification and characterization of alzheimers disease |
| KR101933847B1 (ko) | 2017-05-15 | 2018-12-28 | 조선대학교산학협력단 | 알츠하이머병 위험도와 관련된 apoe 프로모터 단일염기변이 및 이것의 용도 |
| WO2018212371A1 (ko) * | 2017-05-17 | 2018-11-22 | 조선대학교산학협력단 | 알츠하이머병 위험도와 관련된 apoe 프로모터 단일염기변이 및 이것의 용도 |
| JP7399465B2 (ja) * | 2017-05-15 | 2023-12-18 | インフォメディテック・カンパニー，リミテッド | アルツハイマー病の危険性と関連するａｐｏｅプロモーターの一塩基多型およびその使用 |
| WO2019178167A1 (en) * | 2018-03-13 | 2019-09-19 | I2Dx, Inc. | Electronic delivery of information in personalized medicine |
| EP3794345B1 (en) * | 2018-05-18 | 2025-02-26 | Anavex Life Sciences Corp. | Optimized sigma-1 agonist method of responder selection and treatment |
| CN110607364B (zh) * | 2019-11-01 | 2023-04-28 | 北京中医药大学 | 通过检测snp位点确定等位基因的基因型的方法 |
| KR102561438B1 (ko) * | 2020-11-04 | 2023-07-28 | 사회복지법인 삼성생명공익재단 | 뇌 아밀로이드 베타 축적 가능성을 예측하는 방법 |
| JP7731540B2 (ja) * | 2021-03-26 | 2025-09-01 | 国立研究開発法人農業・食品産業技術総合研究機構 | アミロイドβ蓄積リスクの有無の指標とする方法、一塩基多型（ＳＮＰ）の存在又は非存在を検出する方法、組成物、及びキット |
| US20240203524A1 (en) * | 2021-04-13 | 2024-06-20 | Kyoto University | Information processing method, information processing device, and storage medium |
| CL2021001380A1 (es) | 2021-05-26 | 2022-01-14 | Corporacion Centro Int De Biomedicina Icc | Generación de un nuevo anticuerpo monoclonal sitio específico para la proteína tau y su uso como herramienta en biomarcadores específicos para la detección temprana de enfermedades neurodegenerativas y patologías involucradas con la proteína tau como alzheimer y otras demencias. |
| KR102775636B1 (ko) * | 2022-03-15 | 2025-03-05 | 사회복지법인 삼성생명공익재단 | 유럽 인구 데이터 기반 알츠하이머병 치매의 발병 위험군 또는 조기 증상 발현 위험군, 기억상실형 경도인지장애의 발병 위험군 및/또는 아밀로이드β 침착에 대한 PET 양성 위험군을 예측하기 위한 정보를 제공하는 방법 |
| CN114736963B (zh) * | 2022-05-25 | 2023-03-24 | 首都医科大学宣武医院 | 一种用于预测阿尔茨海默病发病风险的物质的组合、试剂盒及应用 |
| US12518859B2 (en) * | 2023-07-26 | 2026-01-06 | Helix, Inc. | Systems and methods for providing test results of gene sequencing data on a recurring basis |
| KR102940935B1 (ko) * | 2024-02-15 | 2026-03-17 | 이화여자대학교 산학협력단 | 고인지예비능 생체표지자로서의 snp 및 이의 이용 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2765591B1 (fr) * | 1997-07-01 | 2002-08-09 | Pasteur Institut | Procede de diagnostic de la maladie d'alzheimer |
| WO2006138716A2 (en) * | 2005-06-17 | 2006-12-28 | Brt Laboratories, Inc. | Thermodynamically defined gene specific primers |
| JP2007166962A (ja) * | 2005-12-21 | 2007-07-05 | Japan Health Science Foundation | アルツハイマー病の予測または診断の方法 |
| EP2082343A2 (en) * | 2006-11-02 | 2009-07-29 | Genizon Biosciences Inc. | Genemap of the human genes associated with asthma disease |
| SG177960A1 (en) * | 2007-04-17 | 2012-02-28 | Santen Pharmaceutical Co Ltd | Method for determination of onset risk of glaucoma |
| CA2766876C (en) * | 2009-07-03 | 2020-01-28 | University College Cardiff Consultants Limited | Variants of clu/apoj, picalm, abca7, cr1 and bin1 gene loci and the ms4a gene cluster for the diagnosis of alzheimer's disease |
-
2010
- 2010-06-22 CA CA2766876A patent/CA2766876C/en active Active
- 2010-06-22 CN CN2010800292599A patent/CN102471800A/zh active Pending
- 2010-06-22 JP JP2012516841A patent/JP5917395B2/ja active Active
- 2010-06-22 US US13/376,485 patent/US20120122703A1/en not_active Abandoned
- 2010-06-22 AU AU2010267835A patent/AU2010267835C1/en not_active Ceased
- 2010-06-22 EP EP15152097.0A patent/EP2891723B1/en not_active Not-in-force
- 2010-06-22 WO PCT/GB2010/001208 patent/WO2011001135A2/en not_active Ceased
- 2010-06-22 EP EP10747062.7A patent/EP2449134B1/en not_active Not-in-force
- 2010-06-22 NZ NZ59661410A patent/NZ596614A/xx unknown
- 2010-06-22 CN CN2013102808899A patent/CN103409511A/zh active Pending
-
2013
- 2013-05-03 US US13/886,473 patent/US20130288906A1/en not_active Abandoned
- 2013-08-07 JP JP2013164509A patent/JP5917460B2/ja active Active
-
2014
- 2014-04-14 US US14/252,153 patent/US20150119264A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2891723A1 (en) | 2015-07-08 |
| US20130288906A1 (en) | 2013-10-31 |
| JP2014012007A (ja) | 2014-01-23 |
| HK1169455A1 (en) | 2013-01-25 |
| EP2891723B1 (en) | 2017-10-04 |
| JP2012531195A (ja) | 2012-12-10 |
| AU2010267835B2 (en) | 2014-11-06 |
| JP5917395B2 (ja) | 2016-05-11 |
| US20120122703A1 (en) | 2012-05-17 |
| CA2766876A1 (en) | 2011-01-06 |
| EP2449134B1 (en) | 2016-07-27 |
| US20150119264A1 (en) | 2015-04-30 |
| CN103409511A (zh) | 2013-11-27 |
| EP2449134A2 (en) | 2012-05-09 |
| WO2011001135A3 (en) | 2011-06-30 |
| JP5917460B2 (ja) | 2016-05-18 |
| CA2766876C (en) | 2020-01-28 |
| WO2011001135A9 (en) | 2011-02-24 |
| CN102471800A (zh) | 2012-05-23 |
| WO2011001135A2 (en) | 2011-01-06 |
| AU2010267835C1 (en) | 2015-02-26 |
| AU2010267835A1 (en) | 2011-12-15 |
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Legal Events
| Date | Code | Title | Description |
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| S38C | Proceedings under section 38 (amendment of specification with leave of commissioner): specification amended | ||
| S38C | Proceedings under section 38 (amendment of specification with leave of commissioner): specification amended | ||
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