MX2013006669A - Conjunto de sondas de oligonucleotido y metodos para perfilado de microbiotica. - Google Patents
Conjunto de sondas de oligonucleotido y metodos para perfilado de microbiotica.Info
- Publication number
- MX2013006669A MX2013006669A MX2013006669A MX2013006669A MX2013006669A MX 2013006669 A MX2013006669 A MX 2013006669A MX 2013006669 A MX2013006669 A MX 2013006669A MX 2013006669 A MX2013006669 A MX 2013006669A MX 2013006669 A MX2013006669 A MX 2013006669A
- Authority
- MX
- Mexico
- Prior art keywords
- seq
- nucleotide sequence
- oligonucleotide
- hybridising
- under conditions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Abstract
La invención proporciona un conjunto de sondas de oligonucleótido, el conjunto que comprende: (a) un oligonucleótido que comprende una secuencia de nucleótidos seleccionada de SEC ID NO 1, SEC ID NO 27 o una secuencia capaz de hibridar a cualquier secuencia bajo condiciones de alta severidad; (b) un oligonucleótido que comprende una secuencia de nucleótidos seleccionada de SEC ID NO 2, SEC ID NO 28 o una secuencia capaz de hibridar a cualquier secuencia bajo condiciones de alta severidad; (c) un oligonucleótido que comprende una secuencia de nucleótidos seleccionada de la SEC ID NO 3, SEC ID NO 29 o una secuencia capaz de hibridar a cualquier secuencia bajo condiciones de alta severidad; (d) un oligonucleótido que comprende una secuencia de nucleótidos seleccionada de SEC ID NO 4, SEC ID NO 30 o una secuencia capaz de hibridar a cualquier secuencia bajo condiciones de alta severidad; y (e) uno o más oligonucleótidos que comprenden un secuencia de nucleótidos seleccionada de aquellas citadas en la tabla 1 o una secuencia capaz de hibridar a cualquier secuencia de nucleótidos citada en la tabla 1 bajo condiciones de alta severidad; y opcionalmente (f) uno o más oligonucleótidos que comprenden una secuencia de nucleótidos seleccionada de aquellas citadas en la tabla 2 y tabla 3 o una secuencia capaz de hibridar a cualquier secuencia de nucleótidos citada en la tabla 2 y tabla 3 bajo condiciones de alta severidad. También se proporcionan métodos para perfilar la microbiota del tracto GI de un sujeto y métodos para diagnosticar o monitorear una enfermedad o condición en un sujeto o para predecir valorar el riesgo de que un sujeto desarrolle una enfermedad o condición en la cual se usa el conjunto de sondas de oligonucleótido de la invención. También se proporcionan kits que comprenden el conjunto de sondas de oligonucleótido de la invención.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1021399.9A GB201021399D0 (en) | 2010-12-16 | 2010-12-16 | Oligonucleotide probe set and methods of microbiota profiling |
| PCT/GB2011/052509 WO2012080754A2 (en) | 2010-12-16 | 2011-12-16 | Oligonucleotide probe set and methods of microbiota profiling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013006669A true MX2013006669A (es) | 2013-11-04 |
| MX343863B MX343863B (es) | 2016-11-25 |
Family
ID=43567352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013006669A MX343863B (es) | 2010-12-16 | 2011-12-16 | Conjunto de sondas de oligonucleotido y metodos para perfilado de microbiotica. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9243297B2 (es) |
| EP (1) | EP2652145B1 (es) |
| AU (1) | AU2011342983B2 (es) |
| BR (1) | BR112013015082A2 (es) |
| CA (1) | CA2821884C (es) |
| DK (1) | DK2652145T3 (es) |
| ES (1) | ES2573133T3 (es) |
| GB (1) | GB201021399D0 (es) |
| MX (1) | MX343863B (es) |
| NZ (1) | NZ612010A (es) |
| PL (1) | PL2652145T3 (es) |
| RU (1) | RU2605913C2 (es) |
| WO (1) | WO2012080754A2 (es) |
| ZA (1) | ZA201304546B (es) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| GB201021399D0 (en) | 2010-12-16 | 2011-01-26 | Genetic Analysis As | Oligonucleotide probe set and methods of microbiota profiling |
| US20150211053A1 (en) * | 2012-08-01 | 2015-07-30 | Bgi-Shenzhen | Biomarkers for diabetes and usages thereof |
| US11003041B2 (en) * | 2014-06-30 | 2021-05-11 | View, Inc. | Power management for electrochromic window networks |
| WO2016014822A1 (en) * | 2014-07-25 | 2016-01-28 | Ge Healthcare Uk Limited | Screening and monitoring the progression of type 2 diabetes by the molecular identification of gut flora using fta as a faecal collection device |
| GB201505364D0 (en) * | 2015-03-27 | 2015-05-13 | Genetic Analysis As | Method for determining gastrointestinal tract dysbiosis |
| CN105199948A (zh) * | 2015-09-29 | 2015-12-30 | 窦晓鸣 | 大肠杆菌的快速检验试剂盒及检测方法 |
| RU2601132C1 (ru) * | 2015-11-27 | 2016-10-27 | федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (государственный университет)" (МФТИ) | Набор синтетических олигонуклеотидов для диагностики болезни крона и неспецифического язвенного колита путем выявления маркерных участков бактериальной днк методом полимеразной цепной реакции |
| US11707493B2 (en) | 2016-05-23 | 2023-07-25 | California Institute Of Technology | Regulate gut microbiota to treat neurodegenerative disorders |
| RU2630669C1 (ru) * | 2016-07-21 | 2017-09-11 | Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" (ФБУН ГНЦ ВБ "Вектор") | Способ определения метилирования сайтов PuCGPy регуляторных областей генов-онкомаркеров колоректального рака методом GLAD-ПЦР-анализа и набор олигонуклеотидных праймеров и флуоресцентно-меченых зондов для осуществления указанного способа |
| GB201617519D0 (en) * | 2016-10-14 | 2016-11-30 | Genetic Analysis As | A companion diagnostic method for use in the treatment of irritable bowel syndrome with dietary interventions or faecal microbiota transplant |
| EA032051B1 (ru) * | 2017-03-22 | 2019-03-29 | Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" | Способ идентификации в микробиомах и отдельных бактериальных геномах композиции бактериальных генов, участвующих в синтезе и метаболизме различных нейроактивных соединений |
| EP3607096A1 (en) * | 2017-04-03 | 2020-02-12 | Bio-Me AS | Microorganism detection methods |
| CA3097521C (en) | 2017-05-15 | 2023-10-17 | Axial Biotherapeutics, Inc. | Inhibitors of microbially induced amyloid |
| CN110914458A (zh) * | 2017-05-17 | 2020-03-24 | 麦克罗比奥私人有限公司 | 生物标志物及其用途 |
| CN110892081A (zh) | 2017-07-17 | 2020-03-17 | 智能Dna股份有限公司 | 诊断菌群失调的方法 |
| WO2019027929A1 (en) * | 2017-08-01 | 2019-02-07 | Axial Biotherapeutics, Inc. | METHODS AND APPARATUS FOR DETERMINING THE RISK OF AUTISM SPECTRUM DISORDER |
| GB201712459D0 (en) | 2017-08-02 | 2017-09-13 | Norges Miljø-Og Biovitenskapelige Univ | Treatment or prevention of gastrointestinal dysbiosis |
| RU2702229C1 (ru) * | 2018-08-09 | 2019-10-07 | федеральное государственное бюджетное образовательное учреждение высшего образования "Башкирский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ лечения атопического дерматита у детей пробиотическими препаратами с учетом результатов микробиологического исследования кала |
| GB201817889D0 (en) | 2018-11-01 | 2018-12-19 | Bio Me As | Microorganism detection methods |
| TR201818373A2 (tr) * | 2018-12-03 | 2020-06-22 | T C Erciyes Ueniversitesi | Bağirsak mi̇krobi̇yomundan alzhei̇mer hastaliğinin teşhi̇si̇ i̇çi̇n mi̇ni̇mal bi̇yobeli̇rteçler ve i̇lgi̇li̇ yeni̇ nesi̇l di̇zi̇leme ki̇ti̇ |
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| GB201021399D0 (en) | 2010-12-16 | 2011-01-26 | Genetic Analysis As | Oligonucleotide probe set and methods of microbiota profiling |
-
2010
- 2010-12-16 GB GBGB1021399.9A patent/GB201021399D0/en not_active Ceased
-
2011
- 2011-12-16 BR BR112013015082A patent/BR112013015082A2/pt not_active Application Discontinuation
- 2011-12-16 WO PCT/GB2011/052509 patent/WO2012080754A2/en active Application Filing
- 2011-12-16 NZ NZ612010A patent/NZ612010A/en active IP Right Revival
- 2011-12-16 PL PL11804757.0T patent/PL2652145T3/pl unknown
- 2011-12-16 CA CA2821884A patent/CA2821884C/en active Active
- 2011-12-16 MX MX2013006669A patent/MX343863B/es active IP Right Grant
- 2011-12-16 DK DK11804757.0T patent/DK2652145T3/en active
- 2011-12-16 AU AU2011342983A patent/AU2011342983B2/en active Active
- 2011-12-16 RU RU2013132761/10A patent/RU2605913C2/ru active
- 2011-12-16 EP EP11804757.0A patent/EP2652145B1/en active Active
- 2011-12-16 ES ES11804757.0T patent/ES2573133T3/es active Active
-
2013
- 2013-06-17 US US13/919,056 patent/US9243297B2/en active Active
- 2013-06-20 ZA ZA2013/04546A patent/ZA201304546B/en unknown
-
2015
- 2015-11-18 US US14/944,289 patent/US9909191B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012080754A2 (en) | 2012-06-21 |
| CA2821884A1 (en) | 2012-06-21 |
| AU2011342983B2 (en) | 2017-03-30 |
| EP2652145B1 (en) | 2016-03-09 |
| DK2652145T3 (en) | 2016-06-13 |
| RU2013132761A (ru) | 2015-01-27 |
| ES2573133T3 (es) | 2016-06-06 |
| RU2605913C2 (ru) | 2016-12-27 |
| WO2012080754A3 (en) | 2013-06-20 |
| BR112013015082A2 (pt) | 2019-09-17 |
| US20160068891A1 (en) | 2016-03-10 |
| ZA201304546B (en) | 2014-03-26 |
| AU2011342983A1 (en) | 2013-07-04 |
| GB201021399D0 (en) | 2011-01-26 |
| US9909191B2 (en) | 2018-03-06 |
| US20130303397A1 (en) | 2013-11-14 |
| PL2652145T3 (pl) | 2016-09-30 |
| CA2821884C (en) | 2022-07-05 |
| EP2652145A2 (en) | 2013-10-23 |
| NZ612010A (en) | 2015-05-29 |
| US9243297B2 (en) | 2016-01-26 |
| MX343863B (es) | 2016-11-25 |
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