ATE324588T1 - Verkapselung von fluoreszierenden partikeln - Google Patents

Verkapselung von fluoreszierenden partikeln

Info

Publication number
ATE324588T1
ATE324588T1 AT00955620T AT00955620T ATE324588T1 AT E324588 T1 ATE324588 T1 AT E324588T1 AT 00955620 T AT00955620 T AT 00955620T AT 00955620 T AT00955620 T AT 00955620T AT E324588 T1 ATE324588 T1 AT E324588T1
Authority
AT
Austria
Prior art keywords
fluorescent
methods
compositions
encapsulation
fluorescent particles
Prior art date
Application number
AT00955620T
Other languages
English (en)
Inventor
Don J Chandler
Original Assignee
Luminex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luminex Corp filed Critical Luminex Corp
Application granted granted Critical
Publication of ATE324588T1 publication Critical patent/ATE324588T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/046—Making microcapsules or microballoons by physical processes, e.g. drying, spraying combined with gelification or coagulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • B01J13/18—In situ polymerisation with all reactants being present in the same phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/149—Particles, e.g. beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1012—Calibrating particle analysers; References therefor
    • G01N2015/1014—Constitution of reference particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/24—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar beta-D-Glucans, i.e. having beta 1,n (n=3,4,6) linkages between saccharide units, e.g. xanthan
    • G01N2400/26—Cellulose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/24—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar beta-D-Glucans, i.e. having beta 1,n (n=3,4,6) linkages between saccharide units, e.g. xanthan
    • G01N2400/28—Chitin, chitosan
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Nanotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT00955620T 1999-08-17 2000-08-17 Verkapselung von fluoreszierenden partikeln ATE324588T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14922799P 1999-08-17 1999-08-17

Publications (1)

Publication Number Publication Date
ATE324588T1 true ATE324588T1 (de) 2006-05-15

Family

ID=22529319

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00955620T ATE324588T1 (de) 1999-08-17 2000-08-17 Verkapselung von fluoreszierenden partikeln

Country Status (6)

Country Link
US (2) US6528165B2 (de)
EP (1) EP1208382B1 (de)
AT (1) ATE324588T1 (de)
AU (1) AU6779200A (de)
DE (1) DE60027576T2 (de)
WO (1) WO2001013119A1 (de)

Families Citing this family (144)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999019515A1 (en) * 1997-10-14 1999-04-22 Luminex Corporation Precision fluorescently dyed particles and methods of making and using same
US6759235B2 (en) 2000-04-06 2004-07-06 Quantum Dot Corporation Two-dimensional spectral imaging system
US6939721B2 (en) * 2000-12-18 2005-09-06 Agilent Technologies, Inc. Fluorescence immunoassays using organo-metallic complexes for energy transfer
US20050164261A1 (en) * 2001-10-09 2005-07-28 Chandler Don J. Multiplexed analysis of clinical specimens apparatus and methods
US8148171B2 (en) 2001-10-09 2012-04-03 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
AU2002362013B2 (en) 2001-11-21 2008-04-24 Applied Biosystems, Llc. Digital assay
FR2832632B1 (fr) * 2001-11-26 2004-04-23 Mane Fils V Capsule a solubilisation et liberation du contenu rapides
US6974592B2 (en) * 2002-04-11 2005-12-13 Ocean Nutrition Canada Limited Encapsulated agglomeration of microcapsules and method for the preparation thereof
JP4833553B2 (ja) * 2002-11-04 2011-12-07 オーシャン・ニュートリション・カナダ・リミテッド 複数の殻を有するマイクロカプセル及びそれらの調製方法
ITMI20030339A1 (it) * 2003-02-26 2004-08-27 Pranha 50 Ltda Metodo, apparato e dispositivi per il risanamento di condotte mediante introduzione di tubi in materiale plastico.
US7260485B2 (en) * 2003-07-18 2007-08-21 Luminex Corporation Method and systems for distinguishing between materials having similar spectra
WO2005008219A2 (en) * 2003-07-18 2005-01-27 Bio-Rad Laboratories, Inc. System and method for multi-analyte detection
US8012768B2 (en) * 2003-07-18 2011-09-06 Bio-Rad Laboratories, Inc. System and method for multi-analyte detection
US7692773B2 (en) * 2003-08-05 2010-04-06 Luminex Corporation Light emitting diode based measurement systems
US7069191B1 (en) 2003-08-06 2006-06-27 Luminex Corporation Methods for reducing the susceptibility of a peak search to signal noise
KR101166180B1 (ko) * 2003-08-13 2012-07-18 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의 제어 방법
US7531700B2 (en) * 2003-09-24 2009-05-12 E.I. Du Pont De Nemours And Company Fluorinated arylethers and methods for use thereof
US7323696B2 (en) 2004-01-09 2008-01-29 Applera Corporation Phosphor particle coded beads
JP2007518106A (ja) * 2004-01-14 2007-07-05 ルミネックス・コーポレーション 測定システムの１つ以上のパラメータを変更するための方法
CA2553025A1 (en) * 2004-01-14 2005-07-28 Luminex Corporation Methods and systems for dynamic range expansion
US7229778B2 (en) * 2004-02-26 2007-06-12 The Procter & Gamble Company Methods for determining the relative benefits and/or evaluating quantitative changes of products on epithelial tissue
CN101056991A (zh) * 2004-04-20 2007-10-17 基因耐克生物医学制品有限公司 检测ncRNA的方法
US7465543B1 (en) 2004-05-21 2008-12-16 The United States Of America, As Represented By The Secretary Of Agriculture Multiplex DNA identification of clinical yeasts using flow cytometry
US7635563B2 (en) * 2004-06-30 2009-12-22 Massachusetts Institute Of Technology High throughput methods relating to microRNA expression analysis
US7229690B2 (en) * 2004-07-26 2007-06-12 Massachusetts Institute Of Technology Microspheres including nanoparticles
WO2006044413A2 (en) 2004-10-12 2006-04-27 Luminex Corporation Methods for forming dyed microspheres and populations of dyed microspheres
EP1828748A1 (de) * 2004-12-17 2007-09-05 Luminex Corporation Systeme, beleuchtungsuntersysteme und verfahren zur erhöhung der durch ein fluorophor emittierten fluoreszenz
US8034450B2 (en) * 2005-01-21 2011-10-11 Ocean Nutrition Canada Limited Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
US6969530B1 (en) 2005-01-21 2005-11-29 Ocean Nutrition Canada Ltd. Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
WO2006117675A1 (en) * 2005-01-27 2006-11-09 Ocean Nutrition Canada Ltd. Fatty acid-benzenediol derivatives and methods of making and using thereof
US20080206316A1 (en) * 2005-01-27 2008-08-28 Colin Barrow Chromium-Fatty Acid Compounds and Methods of Making and Using Thereof
ATE514939T1 (de) * 2005-02-09 2011-07-15 S3I Llc Verfahren und system für die erkennung, klassifizierung und identifizierung von partikeln
US7507588B2 (en) * 2005-04-20 2009-03-24 Becton, Dickinson And Company Multiplex microparticle system
US9968120B2 (en) * 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
ES2547643T3 (es) * 2005-07-12 2015-10-07 Sysmex Corporation Material de referencia para un analizador de partículas
CN102622746B (zh) 2005-09-21 2016-05-25 卢米尼克斯股份有限公司 图像数据处理的方法和系统
US20070141727A1 (en) * 2005-12-15 2007-06-21 Kimberly-Clark Worldwide, Inc. Luminescent metallic cluster particles and uses thereof
US8309025B1 (en) 2006-01-26 2012-11-13 Luminex Corporation Methods and systems for determining composition and completion of an experiment
CA2571904A1 (en) * 2006-02-15 2007-08-15 Fio Corporation System and method of detecting pathogens
US20070207513A1 (en) * 2006-03-03 2007-09-06 Luminex Corporation Methods, Products, and Kits for Identifying an Analyte in a Sample
US8124943B1 (en) 2006-04-06 2012-02-28 Lugade Ananda G Methods and systems for altering fluorescent intensities of a plurality of particles
EP2007224A2 (de) * 2006-04-07 2008-12-31 Ocean Nutrition Canada Limited Emulsionen und mikrokapseln mit stoffen mit geringer grenzflächenspannung, herstellungsverfahren und verwendung
WO2007121436A2 (en) * 2006-04-17 2007-10-25 Luminex Corporation Methods, particles, and kits for determining activity of a kinase
EP2021766A2 (de) * 2006-05-17 2009-02-11 Luminex Corporation Chip-basiertes flusszytometer-system zur analyse fluoreszierend markierter partikel
US8296088B2 (en) 2006-06-02 2012-10-23 Luminex Corporation Systems and methods for performing measurements of one or more materials
CN101479603B (zh) 2006-06-02 2012-11-21 卢米尼克斯股份有限公司 包括使用磁粒子和应用磁场的用于执行一种或多种分析物的测量系统和方法
EP2040682B1 (de) * 2006-06-05 2017-07-26 DSM Nutritional Products AG Mikrokapseln mit verbesserten ummantelungen
WO2008035569A1 (en) * 2006-09-19 2008-03-27 Konica Minolta Medical & Graphic, Inc. Biomolecule detection reagent and biomolecule detection method using the reagent
US8062609B2 (en) 2006-11-10 2011-11-22 Luminex Corporation Flow cytometer and fluidic line assembly with multiple injection needles
EP2857526B1 (de) 2006-12-13 2016-08-17 Luminex Corporation Systeme und Verfahren zur Multiplexanalyse von PCR in Echtzeit
US7833960B2 (en) * 2006-12-15 2010-11-16 International Flavors & Fragrances Inc. Encapsulated active material containing nanoscaled material
CA2580589C (en) * 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
ES2604081T3 (es) 2007-01-10 2017-03-02 Dsm Nutritional Products Ag Microcápsulas que incluyen proteína de guisante
US8114515B2 (en) * 2007-02-05 2012-02-14 Sabic Innovative Plastics Ip B.V. Crosslinked polyester compositions, method of manufacture, and uses thereof
DE102007010860B4 (de) * 2007-03-01 2014-05-15 PolyAn Gesellschaft zur Herstellung von Polymeren für spezielle Anwendungen und Analytik mbH Verfahren zur Identifikation eines Partikels mit zwei oder mehr monodispers eingebetteten Fluorophoren
CA2682826C (en) 2007-04-02 2013-08-13 Fio Corporation System and method of deconvolving multiplexed fluorescence spectral signals generated by quantum dot optical coding technology
US20100040884A1 (en) * 2008-06-04 2010-02-18 Appleton Papers Inc. Benefit agent containing delivery particles
CA2692259C (en) 2007-06-22 2012-07-31 Fio Corporation Systems and methods for manufacturing quantum dot-doped polymer microbeads
EP2174115B1 (de) * 2007-07-09 2013-08-28 Fio Corporation Systeme und verfahren zur verbesserung des fluoreszenznachweises von zielmolekülen in einer testprobe
BRPI0814205A2 (pt) * 2007-07-23 2015-01-27 Fio Corp Método e sistema de coleta, armazenamento, análise e permissão de acesso a dados coletados e analisados associados a indivíduos de testes biológicos e ambientais
JP2010539516A (ja) * 2007-09-17 2010-12-16 ルミネックス コーポレーション フロー内の粒子を識別するためのシステム、記憶媒体、及び方法
US8551763B2 (en) * 2007-10-12 2013-10-08 Fio Corporation Flow focusing method and system for forming concentrated volumes of microbeads, and microbeads formed further thereto
US20090170214A1 (en) * 2007-12-27 2009-07-02 Luminex Corporation Luminescent Reporter Modality for Analyzing an Assay
US20090169866A1 (en) 2007-12-31 2009-07-02 Agnes Ostafin Nanocomposite materials with dynamically adjusting refractive index and methods of making the same
WO2009091643A1 (en) 2008-01-07 2009-07-23 Luminex Corporation Isolation and enumeration of cells from a complex sample matrix
US8318445B2 (en) * 2008-01-07 2012-11-27 Luminex Corporation Immunomagnetic capture and imaging of biological targets
US20100279272A1 (en) * 2008-02-13 2010-11-04 Michael Craig Burrell Multiplexed analysis methods using sers-active nanoparticles
WO2009145813A1 (en) * 2008-03-04 2009-12-03 Qd Vision, Inc. Particles including nanoparticles, uses thereof, and methods
WO2009155704A1 (en) 2008-06-25 2009-12-30 Fio Corporation Bio-threat alert system
EP2329278A4 (de) 2008-08-29 2014-05-14 Fio Corp Tragbare diagnostische testvorrichtung zur einmaligen verwendung sowie zugehöriges system und verfahren zum testen biologischer und ökologischer proben
EP2350651B1 (de) 2008-11-10 2015-01-14 Luminex Corporation Verfahren zur herstellung makroporöser kügelchen
GB0821122D0 (en) * 2008-11-19 2008-12-24 Nanoco Technologies Ltd Semiconductor nanoparticle - based light emitting devices and associated materials and methods
KR101462657B1 (ko) * 2008-12-19 2014-11-17 삼성전자 주식회사 반도체 나노 결정 복합체
CN102348986B (zh) 2009-01-13 2015-05-06 Fio公司 与电子设备和快速诊断测试中的测试盒结合使用的手持诊断测试设备和方法
US20100264371A1 (en) * 2009-03-19 2010-10-21 Nick Robert J Composition including quantum dots, uses of the foregoing, and methods
WO2011031876A1 (en) 2009-09-09 2011-03-17 Qd Vision, Inc. Formulations including nanoparticles
CN102482457B (zh) 2009-09-09 2015-04-15 Qd视光有限公司 包含纳米颗粒的颗粒、其应用和方法
GB0916699D0 (en) * 2009-09-23 2009-11-04 Nanoco Technologies Ltd Semiconductor nanoparticle-based materials
GB0916700D0 (en) * 2009-09-23 2009-11-04 Nanoco Technologies Ltd Semiconductor nanoparticle-based materials
WO2011041657A1 (en) * 2009-10-01 2011-04-07 Cabot Corporation Particulate compositions having plural responses to excitation radiation
GB2475226A (en) 2009-11-03 2011-05-18 Genetic Analysis As Universal Prokaryote 16S ribosome PCR primer pair
US8377334B2 (en) * 2009-12-23 2013-02-19 General Electric Company Coated phosphors, methods of making them, and articles comprising the same
GB201002627D0 (en) 2010-02-16 2010-03-31 Loxbridge Res Llp Aptamer based analyte detection method
PL2539450T3 (pl) 2010-02-25 2016-08-31 Advanced Liquid Logic Inc Sposób wytwarzania bibliotek kwasu nukleinowego
KR101511829B1 (ko) 2010-04-09 2015-04-13 히타치가세이가부시끼가이샤 구상 형광체, 파장 변환형 태양 전지 밀봉재, 태양 전지 모듈 및 이들의 제조 방법
US8274656B2 (en) 2010-06-30 2012-09-25 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device
US8767069B2 (en) 2010-06-30 2014-07-01 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device using light distribution
WO2012068055A2 (en) 2010-11-17 2012-05-24 Advanced Liquid Logic, Inc. Capacitance detection in a droplet actuator
GB201021399D0 (en) 2010-12-16 2011-01-26 Genetic Analysis As Oligonucleotide probe set and methods of microbiota profiling
GB201021397D0 (en) 2010-12-16 2011-01-26 Genetic Analysis As Diagnosis of Crohn's disease
GB201102693D0 (en) 2011-02-16 2011-03-30 Genetic Analysis As Method for identifying neonates at risk for necrotizing enterocolitis
CN103562729A (zh) 2011-05-02 2014-02-05 先进流体逻辑公司 分子诊断平台
WO2012154745A2 (en) 2011-05-09 2012-11-15 Advanced Liquid Logic, Inc. Microfluidic feedback using impedance detection
US9140635B2 (en) 2011-05-10 2015-09-22 Advanced Liquid Logic, Inc. Assay for measuring enzymatic modification of a substrate by a glycoprotein having enzymatic activity
CN104039978A (zh) 2011-09-29 2014-09-10 露美内克丝公司 水解探针
KR101979287B1 (ko) 2011-10-18 2019-08-28 루미넥스 코포레이션 이미지 데이터를 처리하기 위한 방법 및 시스템
MX349562B (es) 2011-12-09 2017-08-02 Pasteur Institut Ensayo de inmuno deteccion multiplex.
US20150177115A1 (en) 2012-04-06 2015-06-25 Slingshot Biosciences Hydrogel particles with tunable optical properties
JP6105061B2 (ja) 2012-06-15 2017-03-29 ルミネックス コーポレーション ガウシアンフィット残差選択基準を用いて画像を正規化するための装置、システム及び方法
WO2014005299A1 (en) * 2012-07-04 2014-01-09 Empire Technology Development Llc Quantum dot-protein complexes, films, and methods of use
WO2014031902A2 (en) 2012-08-23 2014-02-27 The Regents Of The University Of California Spectrally encoded microbeads and methods and devices for making and using same
US20140243231A1 (en) 2013-02-28 2014-08-28 The Terasaki Family Foundation Methods and compositions for the efficient reuse of multiply dyed particles
US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
US12590955B2 (en) 2013-03-15 2026-03-31 Zeon Corporation Methods and systems for processing particles
EP3608022A1 (de) 2013-03-15 2020-02-12 The Trustees of Princeton University Verfahren und vorrichtungen für reinigung mit hohem durchsatz
EP3569313A1 (de) 2013-03-15 2019-11-20 GPB Scientific, LLC Mikrofluidische on-chip-verarbeitung von partikeln
US20140378327A1 (en) 2013-06-19 2014-12-25 Luminex Corporation Real-time multiplexed hydrolysis probe assay using spectrally identifiable microspheres
EP4697022A2 (de) 2013-08-09 2026-02-18 Luminex Corporation Sonden zur verbesserten schmelzunterscheidung und multiplexierung in nukleinsäuretests
WO2015023747A1 (en) 2013-08-13 2015-02-19 Advanced Liquid Logic, Inc. Methods of improving accuracy and precision of droplet metering using an on-actuator reservoir as the fluid input
KR20160081896A (ko) 2013-08-30 2016-07-08 일루미나, 인코포레이티드 친수성 또는 다양한-친수성 표면 상에서의 액적의 조작
DE102013016121A1 (de) 2013-09-27 2015-04-02 Giesecke & Devrient Gmbh Wertdokument und Verfahren zur Überprüfung des Vorliegens desselben
DE102013016134A1 (de) 2013-09-27 2015-04-02 Giesecke & Devrient Gmbh Wertdokument und Verfahren zur Überprüfung des Vorliegens desselben
DE102014016858A1 (de) 2014-02-19 2015-08-20 Giesecke & Devrient Gmbh Sicherheitsmerkmal und Verwendung desselben, Wertdokument und Verfahren zur Prüfung der Echtheit desselben
SG11201609053YA (en) 2014-04-29 2016-11-29 Illumina Inc Multiplexed single cell gene expression analysis using template switch and tagmentation
EP4613872A3 (de) 2014-08-11 2025-11-12 Luminex Corporation Sonden zur verbesserten schmelzunterscheidung und multiplexierung in nukleinsäuretests
EP3256850B1 (de) 2015-02-09 2025-07-09 Slingshot Biosciences, Inc. Hydrogelpartikel mit abstimmbaren optischen eigenschaften und verfahren zur verwendung davon
WO2016154038A1 (en) 2015-03-20 2016-09-29 Illumina, Inc. Fluidics cartridge for use in the vertical or substantially vertical position
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
HK1250543A1 (zh) 2015-08-24 2018-12-21 日本瑞翁株式会社 用於多步骤细胞纯化和浓缩的方法和装置
EP4368715A3 (de) 2015-08-28 2024-07-24 Illumina, Inc. Nukleinsäuresequenzanalyse aus einzelzellen
DE102015014539A1 (de) 2015-11-11 2017-05-11 Giesecke & Devrient Gmbh Sicherheitspigment basierend auf Kern-Hülle-Teilchen und Herstellungsverfahren
DE102015014526A1 (de) 2015-11-11 2017-05-11 Giesecke & Devrient Gmbh Sicherheitspigment, lumineszierendes Polymerharz und Verfahren zum Herstellen desselben
DE102015014537A1 (de) 2015-11-11 2017-05-11 Giesecke & Devrient Gmbh Sicherheitspigment basierend auf Kern-Hülle-Teilchen und Herstellungsverfahren
US20170137133A1 (en) * 2015-11-12 2017-05-18 Goodrich Corporation System, method, and apparatus for dye in search, rescue, and recovery
AU2017246899B2 (en) 2016-04-07 2020-04-09 Illumina, Inc. Methods and systems for construction of normalized nucleic acid libraries
US10941057B2 (en) * 2017-04-28 2021-03-09 U.S. Environmental Protection Agency Highly tunable fluorescent core-shell particles for environmental release simulation and tracking applications
EA202091673A1 (ru) 2018-01-29 2021-02-03 Ст. Джуд Чилдрен'С Рисерч Хоспитал, Инк. Способ амплификации нуклеиновых кислот
KR101906445B1 (ko) 2018-06-29 2018-10-10 (주)이노큐디 양자점 필름의 제조방법, 이로써 제조된 양자점 필름, 및 이를 포함하는 파장변환 시트 및 디스플레이
CN108969494A (zh) * 2018-09-25 2018-12-11 珠海赛隆药业股份有限公司 一种帕瑞昔布钠长效制剂及其制备方法
EP3976715A4 (de) * 2019-05-24 2023-10-04 Coloursmith Labs Inc. Zusammengesetzte teilchen, die einen hydrophoben farbstoff und ein amphiphiles blockcopolymer enthalten, und ihre verwendung in optischen anwendungen
CA3149610A1 (en) 2019-07-31 2021-02-04 BioSkryb Genomics, Inc. Single cell analysis
JP7759328B2 (ja) 2020-01-24 2025-10-23 スリングショット バイオサイエンシーズ， インコーポレイテッド 細胞様較正粒子のための組成物および方法
BR112022019541A2 (pt) 2020-03-30 2022-11-16 Illumina Inc Métodos e composições para preparação de bibliotecas de ácido nucleico
CA3177834A1 (en) 2020-05-04 2021-11-11 Jeffrey Kim Compositions and methods for passive optical barcoding for multiplexed assays
CN112414989B (zh) * 2020-12-16 2022-01-07 江南大学 一种以盐酸四环素-铕作为荧光探针检测三聚氰胺的方法
KR102550507B1 (ko) 2021-10-19 2023-07-04 (주)이노큐디 양자점 복합체를 포함하는 양자점 필름, 및 디스플레이용 파장변환 시트
JP2024539956A (ja) 2021-10-29 2024-10-31 スリングショット バイオサイエンシーズ， インコーポレイテッド フィーダー細胞としておよび合成抗原提示細胞としてのヒドロゲル粒子
CN114479497A (zh) * 2022-02-24 2022-05-13 戴燕萍 一种环保高透明沥青及其制备方法
CN114685907B (zh) * 2022-04-02 2023-09-22 常州大学 一种可调节双疏性荧光聚苯乙烯微球填料的制备方法以及应用
CN119907921A (zh) 2022-05-05 2025-04-29 弹弓生物科学公司 用于血液学的作为红细胞模拟物的工程化颗粒和含有工程化颗粒的组合物
AU2023280490A1 (en) 2022-06-02 2024-12-05 Slingshot Biosciences, Inc. Apoptotic cell mimic
EP4608872A2 (de) 2022-10-26 2025-09-03 Slingshot Biosciences, Inc. Grössenabstimmbare synthetische partikel mit abstimmbaren optischen eigenschaften und verfahren zur verwendung davon zur immunzellenaktivierung
US20240189217A1 (en) * 2022-12-08 2024-06-13 Zachary Shulman Sunscreen composition including a fluorescent agent excitable by an ultraviolet lam
WO2025049609A1 (en) 2023-08-29 2025-03-06 Slingshot Biosciences, Inc. Cd34 stem cell mimics

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3404093A (en) * 1965-03-29 1968-10-01 Magnaflux Corp Fluorescent composition for magnetic particle inspection
US3485758A (en) * 1967-06-27 1969-12-23 Magnaflux Corp Method of making fluorescent magnetic particles
JPS5065678A (de) * 1973-10-23 1975-06-03
DE2436658C2 (de) 1974-07-30 1976-10-14 Siemens Ag Fluessigkristall-anzeigeschirm
US4337999A (en) 1977-08-29 1982-07-06 Sharp Corporation Fluorescent liquid crystal display compositions and devices
US4164559A (en) 1977-09-21 1979-08-14 Cornell Research Foundation, Inc. Collagen drug delivery device
AU526871B2 (en) 1977-12-09 1983-02-03 Howard Machinery Limited Transfer of fragile object between conveyors
SE428332B (sv) 1979-03-08 1983-06-20 Wallac Oy Forfarande for fluorescensspektroskopisk bestemning av biologiskt aktivt emne, sasom hapten, antikropp eller antigen
US4391909A (en) 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4236071A (en) 1979-05-21 1980-11-25 Exxon Research & Engineering Co. Detection of uranium by light induced luminescence
US4298002A (en) 1979-09-10 1981-11-03 National Patent Development Corporation Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation
US4341997A (en) 1979-11-14 1982-07-27 Magnaflux Corporation Magnetic particle inspection process useable with simultaneous illumination by ultra-violet and white light
JPS56135886A (en) 1980-03-26 1981-10-23 Sharp Kk Reflecting type fluorescent liquid crystal indicator
US4336459A (en) 1980-06-11 1982-06-22 Union Carbide Corporation Method and apparatus for detecting fluorescence under ambient light conditions
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4454106A (en) 1982-06-07 1984-06-12 Gansow Otto A Use of metal chelate conjugated monoclonal antibodies
US5052784A (en) 1986-06-23 1991-10-01 Manchester R&D Partnership Fluorescent colored encapsulated liquid crystal apparatus using enhanced scattering
CA1196862A (en) 1983-06-01 1985-11-19 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4689293A (en) 1983-06-06 1987-08-25 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4806355A (en) 1983-06-06 1989-02-21 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4803168A (en) 1983-09-01 1989-02-07 Damon Biotech, Inc. Microencapsulation with polymers
FR2566440B1 (fr) 1984-06-22 1988-07-22 Jalon Michel Fibres de securite et autres matieres rendues luminescentes par un procede de teinture, leurs procedes de realisation et leurs applications
US4677045A (en) 1984-07-27 1987-06-30 International Business Machines Corporation Squarylium charge generating dye and electrophotographic photoconductor
US4534317A (en) 1984-08-30 1985-08-13 Cape Cod Research Procedures for monitoring fish food consumption
US4668049A (en) 1984-12-18 1987-05-26 Itt Corporation Illumination for a scattering type liquid crystal display
US4724094A (en) 1985-02-07 1988-02-09 Magnaflux Corporation Fluorescent magnetic composition and method of making and using same
US5182111A (en) 1987-11-17 1993-01-26 Boston University Research Foundation In vivo delivery of active factors by co-cultured cell implants
US5017501A (en) 1987-11-25 1991-05-21 Abbott Laboratories Preparation of uniformly sized liposomes encapsulating an aqueous liquid
GB2213303B (en) 1987-12-02 1992-01-08 Gen Electric Co Plc Liquid crystal displays
US5237498A (en) 1988-07-08 1993-08-17 Hitachi, Ltd. System and method for computing profits for individual entities of an entity group via use of means to retrieve and process data for specific entities
GB9003593D0 (en) * 1990-02-16 1990-04-11 Pa Consulting Services Improvements in or relating to fluorescence assays
US5326692B1 (en) * 1992-05-13 1996-04-30 Molecular Probes Inc Fluorescent microparticles with controllable enhanced stokes shift
JP3235144B2 (ja) 1991-08-02 2001-12-04 ソニー株式会社 量子箱列の作製方法
US5879920A (en) 1991-10-07 1999-03-09 Genencor International, Inc. Coated enzyme-containing granule
US5354873A (en) 1991-11-20 1994-10-11 Polaroid Corporation Squarylium dyes, and processes and intermediates for the preparation thereof
GB9323498D0 (en) 1993-11-15 1994-01-05 Isis Innovation Making particles of uniform size
US5565554A (en) 1994-07-29 1996-10-15 The Regents Of The University Of California Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores
US5525516B1 (en) 1994-09-30 1999-11-09 Eastman Chem Co Method for tagging petroleum products
US5482890A (en) 1994-10-14 1996-01-09 National Science Council Method of fabricating quantum dot structures
US5895795A (en) 1995-03-04 1999-04-20 Akzo Nobel Nv Composition containing fine solid particles
US5888885A (en) 1997-05-14 1999-03-30 Lucent Technologies Inc. Method for fabricating three-dimensional quantum dot arrays and resulting products
WO1999019515A1 (en) * 1997-10-14 1999-04-22 Luminex Corporation Precision fluorescently dyed particles and methods of making and using same
ATE239801T1 (de) * 1998-01-22 2003-05-15 Luminex Corp Mikropartikel mit multiplen fluoreszenz-signalen

Also Published As

Publication number Publication date
AU6779200A (en) 2001-03-13
EP1208382B1 (de) 2006-04-26
WO2001013119A1 (en) 2001-02-22
US6905766B2 (en) 2005-06-14
US20020096795A1 (en) 2002-07-25
DE60027576T2 (de) 2007-05-03
US20030132538A1 (en) 2003-07-17
EP1208382A1 (de) 2002-05-29
DE60027576D1 (de) 2006-06-01
US6528165B2 (en) 2003-03-04

Similar Documents

Publication Publication Date Title
DE60027576D1 (de) Verkapselung von fluoreszierenden partikeln
TR200400189T2 (tr) Esitalopram içeren kristal yapılı bileşim.
WO2003058199A3 (en) Arrays of microparticles and methods of preparation thereof
AU2002255511A1 (en) Charge tags and separation of nucleic acid molecules
ATE384119T1 (de) Isoprenoidproduktion
BRPI0621071B1 (pt) material fotocrômico, composto químico, método para fazer um material fotocrômico e artigo fotocrômico
ATE377958T1 (de) Grosse glasartige perlen
ATE446678T1 (de) Zusammensetzungen von zu schnellem wachstum fähigen, restriktierten zellen, die proliferation unterdrückende materialien produzieren und ihre verwendung
AU6267000A (en) Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics
ATE418070T1 (de) Dekodierung von matrixsensoren mit mikrokugeln
WO2003083481A3 (de) Lumineszierende, sphärische, nicht autofluoreszierende silicagel-partikel mit veränderbaren emissionsintensitäten und -frequenzen
DE60315808D1 (de) Sphärische pulverkomponenten und diese enthaltende feste kosmetische zusammensetzung
DE60239486D1 (de) Dichtagglomerierte nichtoxidische teilchen und herstellungsverfahren dafür
AU2003248655A1 (en) Reactor systems having a light-interacting component
BR0007275A (pt) Naftopiranos e fenantropiranos anelados em c5-c6com um grupo bicìclico e composições e matrizes
PA8577701A1 (es) Polipeptido t20 pegilado
ATE458816T1 (de) Fluoreszierendes protein aus aequorea coerulescens und ihre verwendungen
DE50105761D1 (de) Stabilisierter roter Phosphor und ein Verfahren zu seiner Herstellung
TR200201459T2 (tr) Okzkarbazepin içeren süspansiyon
TR199902796T2 (xx) Toz deterjan bile�imleri.
WO2000070353A3 (en) High throughput assay systems and methods
ATE267781T1 (de) Tonzusammensetzung
DE69918561D1 (de) Modifizierte gruppen enthaltendes organosiloxan in pestizidzusammensetzungen
PL363944A1 (en) Silicon organic compound containing alkynol groups, material being subject to crosslinking and the form obtained through material crosslinking
MY123549A (en) Powder coating compositions

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties