ATE324588T1 - Verkapselung von fluoreszierenden partikeln - Google Patents

Verkapselung von fluoreszierenden partikeln

Info

Publication number
ATE324588T1
ATE324588T1 AT00955620T AT00955620T ATE324588T1 AT E324588 T1 ATE324588 T1 AT E324588T1 AT 00955620 T AT00955620 T AT 00955620T AT 00955620 T AT00955620 T AT 00955620T AT E324588 T1 ATE324588 T1 AT E324588T1
Authority
AT
Austria
Prior art keywords
fluorescent
methods
compositions
encapsulation
fluorescent particles
Prior art date
Application number
AT00955620T
Other languages
English (en)
Inventor
Don J Chandler
Original Assignee
Luminex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luminex Corp filed Critical Luminex Corp
Application granted granted Critical
Publication of ATE324588T1 publication Critical patent/ATE324588T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/046—Making microcapsules or microballoons by physical processes, e.g. drying, spraying combined with gelification or coagulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • B01J13/18—In situ polymerisation with all reactants being present in the same phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/149—Particles, e.g. beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1012—Calibrating particle analysers; References therefor
    • G01N2015/1014—Constitution of reference particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/24—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar beta-D-Glucans, i.e. having beta 1,n (n=3,4,6) linkages between saccharide units, e.g. xanthan
    • G01N2400/26—Cellulose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/24—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar beta-D-Glucans, i.e. having beta 1,n (n=3,4,6) linkages between saccharide units, e.g. xanthan
    • G01N2400/28—Chitin, chitosan
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Nanotechnology (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Luminescent Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT00955620T 1999-08-17 2000-08-17 Verkapselung von fluoreszierenden partikeln ATE324588T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14922799P 1999-08-17 1999-08-17

Publications (1)

Publication Number Publication Date
ATE324588T1 true ATE324588T1 (de) 2006-05-15

Family

ID=22529319

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00955620T ATE324588T1 (de) 1999-08-17 2000-08-17 Verkapselung von fluoreszierenden partikeln

Country Status (6)

Country Link
US (2) US6528165B2 (de)
EP (1) EP1208382B1 (de)
AT (1) ATE324588T1 (de)
AU (1) AU6779200A (de)
DE (1) DE60027576T2 (de)
WO (1) WO2001013119A1 (de)

Families Citing this family (144)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4357112B2 (ja) * 1997-10-14 2009-11-04 ルミネックス コーポレイション 精密蛍光染色された粒子及びその製造及び使用方法
US6734420B2 (en) 2000-04-06 2004-05-11 Quantum Dot Corporation Differentiable spectral bar code methods and systems
US6939721B2 (en) * 2000-12-18 2005-09-06 Agilent Technologies, Inc. Fluorescence immunoassays using organo-metallic complexes for energy transfer
US20050164261A1 (en) * 2001-10-09 2005-07-28 Chandler Don J. Multiplexed analysis of clinical specimens apparatus and methods
US8148171B2 (en) 2001-10-09 2012-04-03 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
AU2002362013B2 (en) 2001-11-21 2008-04-24 Applied Biosystems, Llc. Digital assay
FR2832632B1 (fr) * 2001-11-26 2004-04-23 Mane Fils V Capsule a solubilisation et liberation du contenu rapides
US6974592B2 (en) * 2002-04-11 2005-12-13 Ocean Nutrition Canada Limited Encapsulated agglomeration of microcapsules and method for the preparation thereof
JP4833553B2 (ja) * 2002-11-04 2011-12-07 オーシャン・ニュートリション・カナダ・リミテッド 複数の殻を有するマイクロカプセル及びそれらの調製方法
ITMI20030339A1 (it) * 2003-02-26 2004-08-27 Pranha 50 Ltda Metodo, apparato e dispositivi per il risanamento di condotte mediante introduzione di tubi in materiale plastico.
US7260485B2 (en) * 2003-07-18 2007-08-21 Luminex Corporation Method and systems for distinguishing between materials having similar spectra
WO2005008219A2 (en) 2003-07-18 2005-01-27 Bio-Rad Laboratories, Inc. System and method for multi-analyte detection
US8012768B2 (en) * 2003-07-18 2011-09-06 Bio-Rad Laboratories, Inc. System and method for multi-analyte detection
US7692773B2 (en) * 2003-08-05 2010-04-06 Luminex Corporation Light emitting diode based measurement systems
US7069191B1 (en) 2003-08-06 2006-06-27 Luminex Corporation Methods for reducing the susceptibility of a peak search to signal noise
KR101149880B1 (ko) * 2003-08-13 2012-05-24 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의 제어 방법
US7531700B2 (en) * 2003-09-24 2009-05-12 E.I. Du Pont De Nemours And Company Fluorinated arylethers and methods for use thereof
WO2005071412A2 (en) 2004-01-09 2005-08-04 Applera Corporation Phosphor particle coded beads
CN1910440A (zh) * 2004-01-14 2007-02-07 卢米尼克斯股份有限公司 用于动态范围扩展的方法和系统
JP2007518106A (ja) * 2004-01-14 2007-07-05 ルミネックス・コーポレーション 測定システムの1つ以上のパラメータを変更するための方法
US7229778B2 (en) * 2004-02-26 2007-06-12 The Procter & Gamble Company Methods for determining the relative benefits and/or evaluating quantitative changes of products on epithelial tissue
CN101056991A (zh) * 2004-04-20 2007-10-17 基因耐克生物医学制品有限公司 检测ncRNA的方法
US7465543B1 (en) 2004-05-21 2008-12-16 The United States Of America, As Represented By The Secretary Of Agriculture Multiplex DNA identification of clinical yeasts using flow cytometry
US7635563B2 (en) * 2004-06-30 2009-12-22 Massachusetts Institute Of Technology High throughput methods relating to microRNA expression analysis
US7229690B2 (en) * 2004-07-26 2007-06-12 Massachusetts Institute Of Technology Microspheres including nanoparticles
CN103951595B (zh) 2004-10-12 2015-10-14 卢米尼克斯股份有限公司 形成染色的微球体和染色的微球体群的方法
EP1828748A1 (de) * 2004-12-17 2007-09-05 Luminex Corporation Systeme, beleuchtungsuntersysteme und verfahren zur erhöhung der durch ein fluorophor emittierten fluoreszenz
US8034450B2 (en) * 2005-01-21 2011-10-11 Ocean Nutrition Canada Limited Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
US6969530B1 (en) 2005-01-21 2005-11-29 Ocean Nutrition Canada Ltd. Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
US20080206316A1 (en) * 2005-01-27 2008-08-28 Colin Barrow Chromium-Fatty Acid Compounds and Methods of Making and Using Thereof
EP1846355B1 (de) * 2005-01-27 2009-12-16 Ocean Nutrition Canada Limited Fettsäure-benzenediol-derivate sowie herstellungs- und verwendungsverfahren dafür
ATE514939T1 (de) * 2005-02-09 2011-07-15 S3I Llc Verfahren und system für die erkennung, klassifizierung und identifizierung von partikeln
WO2006115870A2 (en) * 2005-04-20 2006-11-02 Becton Dickinson And Company Multiplex microparticle system
US9968120B2 (en) * 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
ES2547643T3 (es) 2005-07-12 2015-10-07 Sysmex Corporation Material de referencia para un analizador de partículas
CA2984772C (en) 2005-09-21 2018-04-03 Luminex Corporation Methods and systems for image data processing
US20070141727A1 (en) * 2005-12-15 2007-06-21 Kimberly-Clark Worldwide, Inc. Luminescent metallic cluster particles and uses thereof
US8309025B1 (en) 2006-01-26 2012-11-13 Luminex Corporation Methods and systems for determining composition and completion of an experiment
CA2571904A1 (en) * 2006-02-15 2007-08-15 Fio Corporation System and method of detecting pathogens
WO2007103859A2 (en) * 2006-03-03 2007-09-13 Luminex Corporation Methods, products, and kits for identifying an analyte in a sample
US8124943B1 (en) 2006-04-06 2012-02-28 Lugade Ananda G Methods and systems for altering fluorescent intensities of a plurality of particles
CA2643662A1 (en) * 2006-04-07 2007-10-25 Ocean Nutrition Canada Ltd. Emulsions and microcapsules with substances having low interfacial tension, methods of making and using thereof
WO2007121436A2 (en) * 2006-04-17 2007-10-25 Luminex Corporation Methods, particles, and kits for determining activity of a kinase
US9810707B2 (en) * 2006-05-17 2017-11-07 Luminex Corporation Chip-based flow cytometer type systems for analyzing fluorescently tagged particles
US8296088B2 (en) 2006-06-02 2012-10-23 Luminex Corporation Systems and methods for performing measurements of one or more materials
WO2007143615A2 (en) 2006-06-02 2007-12-13 Luminex Corporation Systems and methods for performing measurements of one or more analytes comprising using magnetic particles and applying a magnetic field
CA2654031C (en) * 2006-06-05 2016-05-24 Ocean Nutrition Canada Limited Microcapsules with improved shells
US20090239767A1 (en) * 2006-09-19 2009-09-24 Konica Minolta Medical & Graphic, Inc. Biomolecule detection reagent and method for detecting biomolecule using reagent
US8062609B2 (en) * 2006-11-10 2011-11-22 Luminex Corporation Flow cytometer and fluidic line assembly with multiple injection needles
CN102851369B (zh) 2006-12-13 2015-01-21 卢米耐克斯公司 用于实时pcr多重分析的系统和方法
US7833960B2 (en) * 2006-12-15 2010-11-16 International Flavors & Fragrances Inc. Encapsulated active material containing nanoscaled material
CA2580589C (en) * 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
WO2008085997A2 (en) 2007-01-10 2008-07-17 Ocean Nutrition Canada, Ltd. Vegetarian microcapsules
US8114515B2 (en) * 2007-02-05 2012-02-14 Sabic Innovative Plastics Ip B.V. Crosslinked polyester compositions, method of manufacture, and uses thereof
DE102007010860B4 (de) * 2007-03-01 2014-05-15 PolyAn Gesellschaft zur Herstellung von Polymeren für spezielle Anwendungen und Analytik mbH Verfahren zur Identifikation eines Partikels mit zwei oder mehr monodispers eingebetteten Fluorophoren
US8360321B2 (en) 2007-04-02 2013-01-29 Fio Corporation System and method of deconvolving multiplexed fluorescence spectral signals generated by quantum dot optical coding technology
US20100040884A1 (en) * 2008-06-04 2010-02-18 Appleton Papers Inc. Benefit agent containing delivery particles
JP2010530912A (ja) 2007-06-22 2010-09-16 フィオ コーポレイション 量子ドットをドープしたポリマーマイクロビーズの製造システム及び方法
WO2009006739A1 (en) * 2007-07-09 2009-01-15 Fio Corporation Systems and methods for enhancing fluorescent detection of target molecules in a test sample
WO2009012585A1 (en) * 2007-07-23 2009-01-29 Fio Corporation A method and system for collating, storing, analyzing and enabling access to collected and analyzed data associated with biological and environmental test subjects
US8171777B2 (en) * 2007-09-17 2012-05-08 Adam Richard Schilffarth Systems, storage mediums, and methods for identifying particles in flow
CN101861203B (zh) * 2007-10-12 2014-01-22 Fio公司 用于形成浓缩体积的微珠的流动聚焦方法和系统以及形成的微珠
US20090170214A1 (en) * 2007-12-27 2009-07-02 Luminex Corporation Luminescent Reporter Modality for Analyzing an Assay
US20090169866A1 (en) 2007-12-31 2009-07-02 Agnes Ostafin Nanocomposite materials with dynamically adjusting refractive index and methods of making the same
JP2011509405A (ja) * 2008-01-07 2011-03-24 ルミネックス コーポレーション 生物学的標的の免疫磁気捕捉および撮像の方法
WO2009091643A1 (en) 2008-01-07 2009-07-23 Luminex Corporation Isolation and enumeration of cells from a complex sample matrix
US20100279272A1 (en) * 2008-02-13 2010-11-04 Michael Craig Burrell Multiplexed analysis methods using sers-active nanoparticles
WO2009145813A1 (en) * 2008-03-04 2009-12-03 Qd Vision, Inc. Particles including nanoparticles, uses thereof, and methods
US9792809B2 (en) 2008-06-25 2017-10-17 Fio Corporation Bio-threat alert system
BRPI0917839A2 (pt) 2008-08-29 2015-11-24 Fio Corp dispositivo de teste de diagnóstico portátil de uso único, e um sistema associado e método para teste de amostras de teste ambientais e biológicas
CN102265155B (zh) 2008-11-10 2014-08-13 卢米耐克斯公司 用于制备和使用多重检测中的大孔珠粒的方法和体系
GB0821122D0 (en) * 2008-11-19 2008-12-24 Nanoco Technologies Ltd Semiconductor nanoparticle - based light emitting devices and associated materials and methods
KR101462657B1 (ko) * 2008-12-19 2014-11-17 삼성전자 주식회사 반도체 나노 결정 복합체
CN104374932A (zh) 2009-01-13 2015-02-25 Fio公司 与电子设备和快速诊断测试中的测试盒结合使用的手持诊断测试设备
US20100264371A1 (en) * 2009-03-19 2010-10-21 Nick Robert J Composition including quantum dots, uses of the foregoing, and methods
WO2011031876A1 (en) 2009-09-09 2011-03-17 Qd Vision, Inc. Formulations including nanoparticles
KR101865888B1 (ko) 2009-09-09 2018-06-08 삼성전자주식회사 나노입자들을 포함하는 입자, 그의 용도, 및 방법
GB0916699D0 (en) * 2009-09-23 2009-11-04 Nanoco Technologies Ltd Semiconductor nanoparticle-based materials
GB0916700D0 (en) * 2009-09-23 2009-11-04 Nanoco Technologies Ltd Semiconductor nanoparticle-based materials
ES2520190T3 (es) * 2009-10-01 2014-11-11 Sicpa Holding Sa Composiciones en partículas que tienen múltiples respuestas a radiación de excitación
GB2475226A (en) 2009-11-03 2011-05-18 Genetic Analysis As Universal Prokaryote 16S ribosome PCR primer pair
US8377334B2 (en) * 2009-12-23 2013-02-19 General Electric Company Coated phosphors, methods of making them, and articles comprising the same
GB201002627D0 (en) 2010-02-16 2010-03-31 Loxbridge Res Llp Aptamer based analyte detection method
DK2539450T3 (da) 2010-02-25 2016-05-30 Advanced Liquid Logic Inc Fremgangsmåde til fremstilling af nukleinsyrebiblioteker
CN105694863A (zh) 2010-04-09 2016-06-22 日立化成株式会社 球状荧光体、波长转换型太阳能电池密封材料、太阳能电池模块、和它们的制造方法
US8767069B2 (en) 2010-06-30 2014-07-01 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device using light distribution
US8274656B2 (en) 2010-06-30 2012-09-25 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device
WO2012068055A2 (en) 2010-11-17 2012-05-24 Advanced Liquid Logic, Inc. Capacitance detection in a droplet actuator
GB201021397D0 (en) 2010-12-16 2011-01-26 Genetic Analysis As Diagnosis of Crohn's disease
GB201021399D0 (en) 2010-12-16 2011-01-26 Genetic Analysis As Oligonucleotide probe set and methods of microbiota profiling
GB201102693D0 (en) 2011-02-16 2011-03-30 Genetic Analysis As Method for identifying neonates at risk for necrotizing enterocolitis
EP2705374A4 (de) 2011-05-02 2014-11-12 Advanced Liquid Logic Inc Molekulare diagnoseplattform
US9188615B2 (en) 2011-05-09 2015-11-17 Advanced Liquid Logic, Inc. Microfluidic feedback using impedance detection
CA2833907A1 (en) 2011-05-10 2012-11-15 Advanced Liquid Logic, Inc. Enzyme concentration and assays
CN108192952A (zh) 2011-09-29 2018-06-22 露美内克丝公司 水解探针
CA2852915C (en) 2011-10-18 2018-05-15 Luminex Corporation Methods and systems for image data processing
JP6215223B2 (ja) 2011-12-09 2017-10-18 アンスティテュ・パストゥール マルチプレックス免疫スクリーニングアッセイ
US20150177115A1 (en) 2012-04-06 2015-06-25 Slingshot Biosciences Hydrogel particles with tunable optical properties
WO2013188857A2 (en) 2012-06-15 2013-12-19 Luminex Corporation Apparatus, system, and method for image normalization using a gaussian residual of fit selection criteria
WO2014005299A1 (en) * 2012-07-04 2014-01-09 Empire Technology Development Llc Quantum dot-protein complexes, films, and methods of use
WO2014031902A2 (en) 2012-08-23 2014-02-27 The Regents Of The University Of California Spectrally encoded microbeads and methods and devices for making and using same
US20140243231A1 (en) 2013-02-28 2014-08-28 The Terasaki Family Foundation Methods and compositions for the efficient reuse of multiply dyed particles
US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
EP3608022A1 (de) 2013-03-15 2020-02-12 The Trustees of Princeton University Verfahren und vorrichtungen für reinigung mit hohem durchsatz
US12590955B2 (en) 2013-03-15 2026-03-31 Zeon Corporation Methods and systems for processing particles
EP2971287B1 (de) 2013-03-15 2019-08-14 GPB Scientific, LLC Mikrofluidische on-chip-verarbeitung von partikeln
US20140378327A1 (en) 2013-06-19 2014-12-25 Luminex Corporation Real-time multiplexed hydrolysis probe assay using spectrally identifiable microspheres
EP3715470B1 (de) 2013-08-09 2023-10-11 Luminex Corporation Sonden für verbesserte schmelzunterscheidung und multiplexierung in nukleinsäuretests
EP3033599A4 (de) 2013-08-13 2017-03-22 Advanced Liquid Logic, Inc. Verfahren zur verbesserung der genauigkeit und präzision der tröpfchendosierung unter verwendung eines behälters auf einem aktuator als flüssigkeitseingabe
JP2016539343A (ja) 2013-08-30 2016-12-15 イルミナ インコーポレイテッド 親水性または斑状親水性表面上の液滴の操作
DE102013016121A1 (de) 2013-09-27 2015-04-02 Giesecke & Devrient Gmbh Wertdokument und Verfahren zur Überprüfung des Vorliegens desselben
DE102013016134A1 (de) 2013-09-27 2015-04-02 Giesecke & Devrient Gmbh Wertdokument und Verfahren zur Überprüfung des Vorliegens desselben
DE102014016858A1 (de) 2014-02-19 2015-08-20 Giesecke & Devrient Gmbh Sicherheitsmerkmal und Verwendung desselben, Wertdokument und Verfahren zur Prüfung der Echtheit desselben
CA3060708A1 (en) 2014-04-29 2015-11-05 Illumina, Inc Multiplexed single cell gene expression analysis using template switch and tagmentation
EP4613872A3 (de) 2014-08-11 2025-11-12 Luminex Corporation Sonden zur verbesserten schmelzunterscheidung und multiplexierung in nukleinsäuretests
JP6692834B2 (ja) 2015-02-09 2020-05-13 スリングショット バイオサイエンシーズ, インコーポレイテッド 調整可能な光学特性を有するヒドロゲル粒子およびその使用の方法
US10576471B2 (en) 2015-03-20 2020-03-03 Illumina, Inc. Fluidics cartridge for use in the vertical or substantially vertical position
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
CA2996529A1 (en) 2015-08-24 2017-03-02 Gpb Scientific, Llc Methods and devices for multi-step cell purification and concentration
AU2016316773B2 (en) 2015-08-28 2020-01-30 Illumina, Inc. Nucleic acid sequence analysis from single cells
DE102015014537A1 (de) 2015-11-11 2017-05-11 Giesecke & Devrient Gmbh Sicherheitspigment basierend auf Kern-Hülle-Teilchen und Herstellungsverfahren
DE102015014539A1 (de) 2015-11-11 2017-05-11 Giesecke & Devrient Gmbh Sicherheitspigment basierend auf Kern-Hülle-Teilchen und Herstellungsverfahren
DE102015014526A1 (de) 2015-11-11 2017-05-11 Giesecke & Devrient Gmbh Sicherheitspigment, lumineszierendes Polymerharz und Verfahren zum Herstellen desselben
US20170137133A1 (en) * 2015-11-12 2017-05-18 Goodrich Corporation System, method, and apparatus for dye in search, rescue, and recovery
WO2017176896A1 (en) 2016-04-07 2017-10-12 Illumina, Inc. Methods and systems for construction of normalized nucleic acid libraries
US10941057B2 (en) * 2017-04-28 2021-03-09 U.S. Environmental Protection Agency Highly tunable fluorescent core-shell particles for environmental release simulation and tracking applications
IL276343B2 (en) 2018-01-29 2024-10-01 St Jude Childrens Res Hospital Inc Method for nucleic acid amplification
KR101906445B1 (ko) 2018-06-29 2018-10-10 (주)이노큐디 양자점 필름의 제조방법, 이로써 제조된 양자점 필름, 및 이를 포함하는 파장변환 시트 및 디스플레이
CN108969494A (zh) * 2018-09-25 2018-12-11 珠海赛隆药业股份有限公司 一种帕瑞昔布钠长效制剂及其制备方法
BR112021023598A2 (pt) * 2019-05-24 2022-02-08 Coloursmith Labs Inc Partículas compostas compreendendo um corante hidrofóbico e um copolímero em bloco anfifílico e uso das mesmas em aplicações ópticas
CA3149610A1 (en) 2019-07-31 2021-02-04 BioSkryb Genomics, Inc. Single cell analysis
TW202141019A (zh) 2020-01-24 2021-11-01 美商史林夏特生化公司 類細胞校正粒子之組合物與方法
EP4127220B1 (de) 2020-03-30 2024-06-05 Illumina, Inc. Verfahren und zusammensetzungen zur herstellung von nukleinsäurebibliotheken
CN115485556B (zh) 2020-05-04 2026-02-03 弹弓生物科学公司 用于多路复用测定的被动光学条形码化的组合物和方法
CN112414989B (zh) * 2020-12-16 2022-01-07 江南大学 一种以盐酸四环素-铕作为荧光探针检测三聚氰胺的方法
KR102550507B1 (ko) 2021-10-19 2023-07-04 (주)이노큐디 양자점 복합체를 포함하는 양자점 필름, 및 디스플레이용 파장변환 시트
EP4423250A1 (de) 2021-10-29 2024-09-04 Slingshot Biosciences, Inc. Hydrogelpartikel als feeder-zellen und als synthetische antigenpräsentierende zellen
CN114479497A (zh) * 2022-02-24 2022-05-13 戴燕萍 一种环保高透明沥青及其制备方法
CN114685907B (zh) * 2022-04-02 2023-09-22 常州大学 一种可调节双疏性荧光聚苯乙烯微球填料的制备方法以及应用
WO2023215886A1 (en) 2022-05-05 2023-11-09 Slingshot Biosciences, Inc. Engineered particles as red blood cell mimics and compositions containing same for hematology
WO2023235885A1 (en) 2022-06-02 2023-12-07 Slingshot Biosciences, Inc. Apoptotic cell mimic
CN120712108A (zh) 2022-10-26 2025-09-26 弹弓生物科学公司 具有可调整光学性质的大小可调整合成颗粒和用于使用其进行免疫细胞激活的方法
US20240189217A1 (en) * 2022-12-08 2024-06-13 Zachary Shulman Sunscreen composition including a fluorescent agent excitable by an ultraviolet lam
CN121986254A (zh) 2023-08-29 2026-05-05 弹弓生物科学公司 Cd34干细胞模拟物

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3404093A (en) * 1965-03-29 1968-10-01 Magnaflux Corp Fluorescent composition for magnetic particle inspection
US3485758A (en) * 1967-06-27 1969-12-23 Magnaflux Corp Method of making fluorescent magnetic particles
JPS5065678A (de) * 1973-10-23 1975-06-03
DE2436658C2 (de) 1974-07-30 1976-10-14 Siemens Ag Fluessigkristall-anzeigeschirm
US4337999A (en) 1977-08-29 1982-07-06 Sharp Corporation Fluorescent liquid crystal display compositions and devices
US4164559A (en) 1977-09-21 1979-08-14 Cornell Research Foundation, Inc. Collagen drug delivery device
AU526871B2 (en) 1977-12-09 1983-02-03 Howard Machinery Limited Transfer of fragile object between conveyors
SE428332B (sv) 1979-03-08 1983-06-20 Wallac Oy Forfarande for fluorescensspektroskopisk bestemning av biologiskt aktivt emne, sasom hapten, antikropp eller antigen
US4391909A (en) 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4236071A (en) 1979-05-21 1980-11-25 Exxon Research & Engineering Co. Detection of uranium by light induced luminescence
US4298002A (en) 1979-09-10 1981-11-03 National Patent Development Corporation Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation
US4341997A (en) 1979-11-14 1982-07-27 Magnaflux Corporation Magnetic particle inspection process useable with simultaneous illumination by ultra-violet and white light
JPS56135886A (en) 1980-03-26 1981-10-23 Sharp Kk Reflecting type fluorescent liquid crystal indicator
US4336459A (en) 1980-06-11 1982-06-22 Union Carbide Corporation Method and apparatus for detecting fluorescence under ambient light conditions
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4454106A (en) 1982-06-07 1984-06-12 Gansow Otto A Use of metal chelate conjugated monoclonal antibodies
US5052784A (en) 1986-06-23 1991-10-01 Manchester R&D Partnership Fluorescent colored encapsulated liquid crystal apparatus using enhanced scattering
CA1196862A (en) 1983-06-01 1985-11-19 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4806355A (en) 1983-06-06 1989-02-21 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4689293A (en) 1983-06-06 1987-08-25 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4803168A (en) 1983-09-01 1989-02-07 Damon Biotech, Inc. Microencapsulation with polymers
FR2566440B1 (fr) 1984-06-22 1988-07-22 Jalon Michel Fibres de securite et autres matieres rendues luminescentes par un procede de teinture, leurs procedes de realisation et leurs applications
US4677045A (en) 1984-07-27 1987-06-30 International Business Machines Corporation Squarylium charge generating dye and electrophotographic photoconductor
US4534317A (en) 1984-08-30 1985-08-13 Cape Cod Research Procedures for monitoring fish food consumption
US4668049A (en) 1984-12-18 1987-05-26 Itt Corporation Illumination for a scattering type liquid crystal display
US4724094A (en) 1985-02-07 1988-02-09 Magnaflux Corporation Fluorescent magnetic composition and method of making and using same
US5182111A (en) 1987-11-17 1993-01-26 Boston University Research Foundation In vivo delivery of active factors by co-cultured cell implants
US5017501A (en) 1987-11-25 1991-05-21 Abbott Laboratories Preparation of uniformly sized liposomes encapsulating an aqueous liquid
GB2213303B (en) 1987-12-02 1992-01-08 Gen Electric Co Plc Liquid crystal displays
US5237498A (en) 1988-07-08 1993-08-17 Hitachi, Ltd. System and method for computing profits for individual entities of an entity group via use of means to retrieve and process data for specific entities
GB9003593D0 (en) * 1990-02-16 1990-04-11 Pa Consulting Services Improvements in or relating to fluorescence assays
US5326692B1 (en) * 1992-05-13 1996-04-30 Molecular Probes Inc Fluorescent microparticles with controllable enhanced stokes shift
JP3235144B2 (ja) 1991-08-02 2001-12-04 ソニー株式会社 量子箱列の作製方法
US5879920A (en) 1991-10-07 1999-03-09 Genencor International, Inc. Coated enzyme-containing granule
US5354873A (en) 1991-11-20 1994-10-11 Polaroid Corporation Squarylium dyes, and processes and intermediates for the preparation thereof
GB9323498D0 (en) 1993-11-15 1994-01-05 Isis Innovation Making particles of uniform size
US5565554A (en) 1994-07-29 1996-10-15 The Regents Of The University Of California Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores
US5525516B1 (en) 1994-09-30 1999-11-09 Eastman Chem Co Method for tagging petroleum products
US5482890A (en) 1994-10-14 1996-01-09 National Science Council Method of fabricating quantum dot structures
SK115397A3 (en) 1995-03-04 1998-02-04 Akzo Nobel Nv Composition containing fine solid particles, method of producing said composition and its use
US5888885A (en) 1997-05-14 1999-03-30 Lucent Technologies Inc. Method for fabricating three-dimensional quantum dot arrays and resulting products
JP4357112B2 (ja) * 1997-10-14 2009-11-04 ルミネックス コーポレイション 精密蛍光染色された粒子及びその製造及び使用方法
WO1999037814A1 (en) * 1998-01-22 1999-07-29 Luminex Corporation Microparticles with multiple fluorescent signals

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US20020096795A1 (en) 2002-07-25
AU6779200A (en) 2001-03-13
US6528165B2 (en) 2003-03-04
US20030132538A1 (en) 2003-07-17
DE60027576D1 (de) 2006-06-01
WO2001013119A1 (en) 2001-02-22
DE60027576T2 (de) 2007-05-03
US6905766B2 (en) 2005-06-14

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