NZ595982A - Method and apparatus for isolating a target bioentity from a biological sample - Google Patents

Method and apparatus for isolating a target bioentity from a biological sample

Info

Publication number
NZ595982A
NZ595982A NZ595982A NZ59598210A NZ595982A NZ 595982 A NZ595982 A NZ 595982A NZ 595982 A NZ595982 A NZ 595982A NZ 59598210 A NZ59598210 A NZ 59598210A NZ 595982 A NZ595982 A NZ 595982A
Authority
NZ
New Zealand
Prior art keywords
flow path
fluid flow
biological sample
magnetic field
module
Prior art date
Application number
NZ595982A
Other languages
English (en)
Inventor
Howard Milne Chandler
Michael Bruce Chandler
Original Assignee
Clinical Genomics Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clinical Genomics Pty Ltd filed Critical Clinical Genomics Pty Ltd
Publication of NZ595982A publication Critical patent/NZ595982A/xx

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/28Magnetic plugs and dipsticks
    • B03C1/288Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/18Magnetic separation whereby the particles are suspended in a liquid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NZ595982A 2009-04-22 2010-04-22 Method and apparatus for isolating a target bioentity from a biological sample NZ595982A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17153209P 2009-04-22 2009-04-22
US18266109P 2009-05-29 2009-05-29
US28528609P 2009-12-10 2009-12-10
PCT/AU2010/000459 WO2010121315A1 (en) 2009-04-22 2010-04-22 Method and apparatus for isolating a target bioentity from a biological sample

Publications (1)

Publication Number Publication Date
NZ595982A true NZ595982A (en) 2013-10-25

Family

ID=43010599

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ595982A NZ595982A (en) 2009-04-22 2010-04-22 Method and apparatus for isolating a target bioentity from a biological sample

Country Status (9)

Country Link
US (1) US20120115167A1 (enExample)
EP (1) EP2421654A1 (enExample)
JP (1) JP2012524885A (enExample)
CN (1) CN102458665A (enExample)
AU (1) AU2010239154A1 (enExample)
IL (1) IL215807A0 (enExample)
NZ (1) NZ595982A (enExample)
RU (1) RU2011147219A (enExample)
WO (1) WO2010121315A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103261439B (zh) 2010-11-09 2015-04-15 阿塞迪生物技术有限公司 母体血液中的胎儿细胞的富集和识别及这类用途的配体
WO2012113028A1 (en) * 2011-02-23 2012-08-30 Clinical Genomics Pty. Ltd. Isolation of a target bioentity from a biological sample
US20140295420A1 (en) * 2011-06-15 2014-10-02 Koninklijke Philips N.V. Processing of biological sample components
WO2013003898A1 (en) * 2011-07-07 2013-01-10 Clinical Genomics Pty. Ltd Method for detection of cancer in a patient
DE102011088741B4 (de) 2011-12-15 2013-07-25 Institut für Bioprozess- und Analysenmesstechnik e.V. Verfahren und Anordnung zum Markieren und Separieren von Zellen aus einer Zellsuspension
US9637775B2 (en) 2012-02-13 2017-05-02 Neumodx Molecular, Inc. System and method for processing biological samples
US11931740B2 (en) 2012-02-13 2024-03-19 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US9604213B2 (en) 2012-02-13 2017-03-28 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
CN104254595A (zh) 2012-02-13 2014-12-31 纽莫德克斯莫勒库拉尔公司 用于处理和检测核酸的微流体盒
US20140024136A1 (en) * 2012-07-19 2014-01-23 Derek L. Chappell Magnetic particle separator
CN102911864B (zh) * 2012-10-15 2014-08-06 宁波美晶医疗技术有限公司 一种血液中稀有细胞的分离仪
US20140120544A1 (en) 2012-10-25 2014-05-01 Neumodx Molecular, Inc. Method and materials for isolation of nucleic acid materials
CN103131634B (zh) * 2013-02-25 2014-09-03 宁波美晶医疗技术有限公司 一种基于微磁场的免疫肿瘤细胞筛选系统
CN103131693B (zh) * 2013-02-25 2014-12-24 宁波美晶医疗技术有限公司 一种血液中稀有细胞的分离方法
US10202577B2 (en) 2013-10-18 2019-02-12 The General Hospital Corporation Microfluidic sorting using high gradient magnetic fields
CN103940997B (zh) * 2014-03-21 2017-01-04 上海柏慧康生物科技有限公司 一种乳腺癌循环肿瘤细胞检测系统及试剂盒
WO2016084102A1 (en) * 2014-11-28 2016-06-02 Indian Institute Of Technology Delhi Magnetic capturing of rare cells
EP3061529A1 (en) * 2015-02-24 2016-08-31 AdnaGen GmbH Apparatus and method for the analysis, isolation and/or enrichment of target structures in a fluid sample
EP3998335A3 (en) 2015-05-08 2022-07-27 Biomagnetic Solutions LLC Apparatus and method for immunomagnetic cell separation
EP4252898A3 (en) * 2015-09-18 2023-11-29 Redbud Labs, Inc. Flow cells utilizing surface-attached structures, and related systems and methods
JP2018534588A (ja) * 2015-09-22 2018-11-22 パーデュー・リサーチ・ファウンデーションPurdue Research Foundation 稀少細胞の遠心分離なしの単離および検出
CA3086405A1 (en) 2018-01-05 2019-07-11 Path Ex, Inc. Device for the capture and removal of disease material from fluids
JP7396777B2 (ja) * 2018-09-28 2023-12-12 オクタン バイオテック インコーポレーテッド 磁気分離
WO2020086761A1 (en) * 2018-10-24 2020-04-30 Path Ex, Inc. Method for the capture and isolation of disease material from flowing matter
AU2020289708C1 (en) 2019-06-07 2024-12-12 Arcedi Biotech Aps Isolation of fetal cells using FACS
CA3152196A1 (en) * 2019-08-30 2021-03-04 Flodesign Sonics, Inc. Acoustic affinity cell selection for multiple target receptors
CN113125707A (zh) * 2020-01-10 2021-07-16 陈琪 一种分离磁微粒的方法、装置及设备
AU2023375445A1 (en) * 2022-11-08 2025-05-15 Zhong Li Methods for detecting target compounds and uses thereof

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575805A (en) * 1976-03-12 1980-10-01 Technicon Instr Automatic diagnostic apparatus
FI903345A7 (fi) * 1988-01-04 1990-07-03 Du Pont Monivaiheinen affiniteettimenetelmä spesifisten solujen eristämiseksi soluseoksesta
US5795470A (en) * 1991-03-25 1998-08-18 Immunivest Corporation Magnetic separation apparatus
WO1996026011A1 (en) * 1995-02-21 1996-08-29 Siddiqi Iqbal W Apparatus and method for mixing and separation employing magnetic particles
US5705059A (en) * 1995-02-27 1998-01-06 Miltenyi; Stefan Magnetic separation apparatus
FR2748569B1 (fr) * 1996-05-07 1998-08-07 Biocom Sa Procede et installation de separation de particules magnetiques dans un fluide pour l'analyse biologique, et application dudit procede
US20030095897A1 (en) * 2001-08-31 2003-05-22 Grate Jay W. Flow-controlled magnetic particle manipulation
CN1230531C (zh) * 2002-12-09 2005-12-07 清华大学 从样品中分离细胞粒子的方法
US7553625B2 (en) * 2003-12-22 2009-06-30 John Wayne Cancer Institute Method and apparatus for in vivo collection of circulating biological components
JP2006010529A (ja) * 2004-06-25 2006-01-12 Canon Inc 磁性粒子分離装置および分離方法
JP2006051850A (ja) * 2004-08-10 2006-02-23 Matsushita Electric Ind Co Ltd 運転支援装置及び運転支援方法
US20090305236A1 (en) * 2005-05-11 2009-12-10 Genetic Technologies Limited Methods of enriching fetal cells
JP2007010500A (ja) * 2005-06-30 2007-01-18 Canon Inc サンプル検出装置とそれを含む検体分析装置
WO2007092713A2 (en) * 2006-02-02 2007-08-16 Trustees Of The University Of Pennsylvania Microfluidic system and method for analysis of gene expression in cell-containing samples and detection of disease
JP2009530606A (ja) * 2006-03-13 2009-08-27 ギロス パテント アーべー 増強型磁気粒子ステアリング
CN100546724C (zh) * 2006-06-30 2009-10-07 上海师范大学 磁性分离柱及其在生物样品分离中的应用
CN101842161A (zh) * 2007-08-23 2010-09-22 辛温尼奥生物系统公司 用于目标物质的俘获磁性拣选系统
WO2009117611A2 (en) * 2008-03-19 2009-09-24 Cynvenio Biosystems, Llc Trapping magnetic cell sorting system
US20110137018A1 (en) * 2008-04-16 2011-06-09 Cynvenio Biosystems, Inc. Magnetic separation system with pre and post processing modules
US8377669B2 (en) * 2009-11-17 2013-02-19 Abbott Point Of Care Inc. Reducing leukocyte interference in non-competitive immunoassays

Also Published As

Publication number Publication date
RU2011147219A (ru) 2013-05-27
AU2010239154A1 (en) 2011-11-10
WO2010121315A1 (en) 2010-10-28
JP2012524885A (ja) 2012-10-18
IL215807A0 (en) 2012-01-31
CN102458665A (zh) 2012-05-16
EP2421654A1 (en) 2012-02-29
US20120115167A1 (en) 2012-05-10

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Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 22 APR 2017 BY DAVIES COLLISON CAVE

Effective date: 20140129

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