NZ570750A - Polypeptides for inducing a protective immune response against staphylococcus aureus - Google Patents
Polypeptides for inducing a protective immune response against staphylococcus aureusInfo
- Publication number
- NZ570750A NZ570750A NZ570750A NZ57075004A NZ570750A NZ 570750 A NZ570750 A NZ 570750A NZ 570750 A NZ570750 A NZ 570750A NZ 57075004 A NZ57075004 A NZ 57075004A NZ 570750 A NZ570750 A NZ 570750A
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- NZ
- New Zealand
- Prior art keywords
- seq
- polypeptide
- amino acid
- sequence
- yeast
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48984003P | 2003-07-24 | 2003-07-24 | |
| US52011503P | 2003-11-14 | 2003-11-14 | |
| NZ544542A NZ544542A (en) | 2003-07-24 | 2004-07-22 | Polypeptides for inducing a protective immune response against staphylococcus aureus |
| PCT/US2004/023523 WO2005009379A2 (en) | 2003-07-24 | 2004-07-22 | Polypeptides for inducing a protective immune response against staphylococcus aureus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ570750A true NZ570750A (en) | 2009-12-24 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ570750A NZ570750A (en) | 2003-07-24 | 2004-07-22 | Polypeptides for inducing a protective immune response against staphylococcus aureus |
| NZ544542A NZ544542A (en) | 2003-07-24 | 2004-07-22 | Polypeptides for inducing a protective immune response against staphylococcus aureus |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ544542A NZ544542A (en) | 2003-07-24 | 2004-07-22 | Polypeptides for inducing a protective immune response against staphylococcus aureus |
Country Status (23)
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT410798B (de) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| EP1725575B1 (en) * | 2004-02-18 | 2012-11-28 | Merck Sharp & Dohme Corp. | Polypeptides for inducing a protective immune response against staphylococcus aureus |
| WO2006059247A2 (en) * | 2004-10-25 | 2006-06-08 | The University Of Western Ontario | VACCINES, COMPOSITIONS AND METHODS BASED ON STAPHYLOCOCCUS AUREUS IRON-REGULATED SURFACE DETERMINANTS IsdA, IsdB, and IsdC |
| GB0526038D0 (en) * | 2005-12-21 | 2006-02-01 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| JP2009524428A (ja) * | 2006-01-27 | 2009-07-02 | メルク エンド カムパニー インコーポレーテッド | スタヒロコッカス・アウレウスｏｒｆ０６５７ｎを標的とする抗原結合タンパク質 |
| AU2008251982A1 (en) | 2007-01-24 | 2008-11-20 | Merck Sharp & Dohme Corp. | Polypeptides for inducing a protective immune response against Staphylococcus epidermidis |
| ATE537839T1 (de) * | 2007-05-04 | 2012-01-15 | Martin Kroenke | Impfstoff zum schutz gegen staphylococcus aureus auf der basis zellwandassoziierter proteine |
| MX2009012891A (es) * | 2007-05-31 | 2009-12-10 | Merck & Co Inc | Proteinas de union a antigeno dirigidas a staphylococcus aureus orf0657n. |
| WO2009022236A2 (en) | 2007-08-16 | 2009-02-19 | Tripep Ab | Immunogen platform |
| US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
| AU2008292897B2 (en) | 2007-08-31 | 2015-01-22 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
| WO2010014304A1 (en) | 2008-07-29 | 2010-02-04 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
| AU2009319947A1 (en) | 2008-11-26 | 2010-06-03 | Merck Sharp & Dohme Corp. | Polypeptides for inducing a protective immune response against Staphylococcus aureus |
| SI3281947T1 (sl) | 2009-04-03 | 2020-07-31 | The University Of Chicago | Sestave in metode v zvezi z variantami proteina A (SPA) |
| DK2510947T3 (en) | 2009-04-14 | 2016-03-21 | Glaxosmithkline Biolog Sa | Compositions for Immunization against Staphylococcus aureus. |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| MX373250B (es) | 2009-09-30 | 2020-05-04 | Glaxosmithkline Biologicals S A Star | Conjugación de polisacáridos capsulares de tipo 5 y de tipo 8 de staphylococcus aureus. |
| EP3199177A1 (en) | 2009-10-30 | 2017-08-02 | GlaxoSmithKline Biologicals S.A. | Purification of staphylococcus aureus type 5 and type 8 capsular saccharides |
| GB0919690D0 (en) | 2009-11-10 | 2009-12-23 | Guy S And St Thomas S Nhs Foun | compositions for immunising against staphylococcus aureus |
| EP2544709A4 (en) * | 2010-03-12 | 2014-01-08 | Univ Pennsylvania | METHOD FOR PREVENTING AND TREATING THE COLONIZATION OF STAPHYLOCOCCUS AUREUS AND THEIR INFECTIOUS DISEASES AND DISEASES |
| CA2803298C (en) | 2010-07-02 | 2020-07-14 | The University Of Chicago | Compositions and methods related to protein a (spa) variants |
| US8747858B2 (en) | 2010-07-13 | 2014-06-10 | Merck Sharp & Dohme Corp. | Staphylococcus aureus surface protein SA1789 and protective vaccine based thereon |
| WO2012065034A1 (en) | 2010-11-12 | 2012-05-18 | Merck Sharp & Dohme Corp. | Enolase peptide conjugate vaccines against staphylococcus aureus |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| US20140363461A1 (en) | 2011-09-01 | 2014-12-11 | Fabio Bagnoli | Adjuvanted formulations of staphylococcus aureus antigens |
| EP2773370A4 (en) | 2011-10-31 | 2016-09-28 | Merck Sharp & Dohme | PROTECTIVE VACCINE BASED ON THE STAPHYLOCOCCUS AUREUS PROTEIN SA2451 |
| CA2871880A1 (en) * | 2012-06-27 | 2014-01-03 | F. Hoffmann-La Roche Ag | Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof |
| RU2015100656A (ru) | 2012-06-27 | 2016-08-20 | Ф. Хоффманн-Ля Рош Аг | Способ получения конъюгатов fc-фрагмента антитела, включающих по меньшей мере одну связывающую группировку, которая специфически связывается с мишенью, и их применения |
| EP2872173A4 (en) | 2012-07-10 | 2016-03-23 | Merck Sharp & Dohme | PROTECTIVE VACCINE BASED ON THE STAPHYLOCOCCUS AUREUS PROTEIN SA2493 |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| CA2373221A1 (en) * | 1999-05-03 | 2000-11-30 | Yashwant M. Deo | Human antibodies to staphylococcus aureus |
| GB0014907D0 (en) * | 2000-06-20 | 2000-08-09 | Univ Sheffield | Antigenic polypeptides |
| AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| EP2339344A1 (en) * | 2001-06-15 | 2011-06-29 | Inhibitex, Inc. | Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus |
| ES2322338T3 (es) * | 2001-11-12 | 2009-06-19 | Novo Nordisk A/S | Purificacion de peptidos por medio de cromatografia de afinidad con iones metalicos. |
| ATE419005T1 (de) * | 2001-12-11 | 2009-01-15 | Merck & Co Inc | Staphylococcus aureus exopolysaccharid und verfahren |
| US20080050361A1 (en) * | 2004-10-25 | 2008-02-28 | Heinrichs David E | Staphylococcus aureas specific anti-infectives |
| EP2368570A3 (en) * | 2006-01-18 | 2012-05-02 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
-
2004
- 2004-07-22 EP EP04778847A patent/EP1651166B8/en not_active Expired - Lifetime
- 2004-07-22 US US10/564,458 patent/US20060177462A1/en not_active Abandoned
- 2004-07-22 DK DK04778847.6T patent/DK1651166T3/da active
- 2004-07-22 KR KR1020067001610A patent/KR20060065643A/ko not_active Ceased
- 2004-07-22 HR HR20100240T patent/HRP20100240T1/hr unknown
- 2004-07-22 JP JP2006521226A patent/JP2007502101A/ja active Pending
- 2004-07-22 RU RU2006105498/13A patent/RU2337108C2/ru not_active IP Right Cessation
- 2004-07-22 PL PL04778847T patent/PL1651166T3/pl unknown
- 2004-07-22 BR BRPI0412799-4A patent/BRPI0412799A/pt not_active Application Discontinuation
- 2004-07-22 NZ NZ570750A patent/NZ570750A/en not_active IP Right Cessation
- 2004-07-22 CA CA002532370A patent/CA2532370A1/en not_active Abandoned
- 2004-07-22 MX MXPA06000854A patent/MXPA06000854A/es active IP Right Grant
- 2004-07-22 SI SI200431389T patent/SI1651166T1/sl unknown
- 2004-07-22 NZ NZ544542A patent/NZ544542A/en not_active IP Right Cessation
- 2004-07-22 PT PT04778847T patent/PT1651166E/pt unknown
- 2004-07-22 AU AU2004258979A patent/AU2004258979B2/en not_active Ceased
- 2004-07-22 WO PCT/US2004/023523 patent/WO2005009379A2/en not_active Ceased
- 2004-07-22 ES ES04778847T patent/ES2342778T3/es not_active Expired - Lifetime
- 2004-07-22 DE DE602004025579T patent/DE602004025579D1/de not_active Expired - Lifetime
- 2004-07-22 AT AT04778847T patent/ATE457737T1/de active
-
2005
- 2005-12-30 IS IS8213A patent/IS8213A/is unknown
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2006
- 2006-01-19 IL IL173253A patent/IL173253A0/en unknown
- 2006-02-23 NO NO20060898A patent/NO20060898L/no not_active Application Discontinuation
-
2010
- 2010-04-30 US US12/771,345 patent/US20100247561A1/en not_active Abandoned
- 2010-05-14 CY CY20101100419T patent/CY1110028T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IS8213A (is) | 2005-12-30 |
| WO2005009379A3 (en) | 2006-11-30 |
| JP2007502101A (ja) | 2007-02-08 |
| CA2532370A1 (en) | 2005-02-03 |
| ATE457737T1 (de) | 2010-03-15 |
| SI1651166T1 (sl) | 2010-06-30 |
| AU2004258979B2 (en) | 2007-12-06 |
| IL173253A0 (en) | 2006-06-11 |
| BRPI0412799A (pt) | 2006-09-26 |
| US20060177462A1 (en) | 2006-08-10 |
| ES2342778T3 (es) | 2010-07-14 |
| NO20060898L (no) | 2006-04-24 |
| EP1651166A2 (en) | 2006-05-03 |
| DK1651166T3 (da) | 2010-05-31 |
| PL1651166T3 (pl) | 2010-08-31 |
| RU2337108C2 (ru) | 2008-10-27 |
| HRP20100240T1 (hr) | 2010-09-30 |
| EP1651166A4 (en) | 2008-03-05 |
| US20100247561A1 (en) | 2010-09-30 |
| NZ544542A (en) | 2009-01-31 |
| DE602004025579D1 (de) | 2010-04-01 |
| WO2005009379A2 (en) | 2005-02-03 |
| EP1651166B1 (en) | 2010-02-17 |
| MXPA06000854A (es) | 2006-03-30 |
| KR20060065643A (ko) | 2006-06-14 |
| PT1651166E (pt) | 2010-04-23 |
| CY1110028T1 (el) | 2015-01-14 |
| RU2006105498A (ru) | 2006-09-10 |
| AU2004258979A1 (en) | 2005-02-03 |
| EP1651166B8 (en) | 2010-05-19 |
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| LAPS | Patent lapsed |