NO20060898L - Polypeptider til indusering av en beskyttende immunrespons mot Staphylococcus aurcus - Google Patents
Polypeptider til indusering av en beskyttende immunrespons mot Staphylococcus aurcusInfo
- Publication number
- NO20060898L NO20060898L NO20060898A NO20060898A NO20060898L NO 20060898 L NO20060898 L NO 20060898L NO 20060898 A NO20060898 A NO 20060898A NO 20060898 A NO20060898 A NO 20060898A NO 20060898 L NO20060898 L NO 20060898L
- Authority
- NO
- Norway
- Prior art keywords
- polypeptides
- immune response
- protective immune
- induce
- seq
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Foreliggende oppfinnelse frembringer polypeptider som omfatter en aminosyresekvens som er strukturelt beslektet med Sekv. Id. nr.1, anvendelse av slike polypeptider og uttrykkingssystemer for fremstiling av slike polypeptider. Sekv. Id. nr.1 er et trunkert derivat av et fullengde -S. aureus- polypeptid. Fullengde polypeptidet blir her referert til som fullengde -"ORF0657n". Polypeptider som inneholder aminosyresekvensen ifølge Sekv. Id. nr.1 ble funnet å frembringe en beskyttende immunrespons mot S. aureus.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48984003P | 2003-07-24 | 2003-07-24 | |
US52011503P | 2003-11-14 | 2003-11-14 | |
PCT/US2004/023523 WO2005009379A2 (en) | 2003-07-24 | 2004-07-22 | Polypeptides for inducing a protective immune response against staphylococcus aureus |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20060898L true NO20060898L (no) | 2006-04-24 |
Family
ID=34107815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20060898A NO20060898L (no) | 2003-07-24 | 2006-02-23 | Polypeptider til indusering av en beskyttende immunrespons mot Staphylococcus aurcus |
Country Status (23)
Country | Link |
---|---|
US (2) | US20060177462A1 (no) |
EP (1) | EP1651166B8 (no) |
JP (1) | JP2007502101A (no) |
KR (1) | KR20060065643A (no) |
AT (1) | ATE457737T1 (no) |
AU (1) | AU2004258979B2 (no) |
BR (1) | BRPI0412799A (no) |
CA (1) | CA2532370A1 (no) |
CY (1) | CY1110028T1 (no) |
DE (1) | DE602004025579D1 (no) |
DK (1) | DK1651166T3 (no) |
ES (1) | ES2342778T3 (no) |
HR (1) | HRP20100240T1 (no) |
IL (1) | IL173253A0 (no) |
IS (1) | IS8213A (no) |
MX (1) | MXPA06000854A (no) |
NO (1) | NO20060898L (no) |
NZ (2) | NZ544542A (no) |
PL (1) | PL1651166T3 (no) |
PT (1) | PT1651166E (no) |
RU (1) | RU2337108C2 (no) |
SI (1) | SI1651166T1 (no) |
WO (1) | WO2005009379A2 (no) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT410798B (de) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
EP1725575B1 (en) * | 2004-02-18 | 2012-11-28 | Merck Sharp & Dohme Corp. | Polypeptides for inducing a protective immune response against staphylococcus aureus |
KR20070085457A (ko) * | 2004-10-25 | 2007-08-27 | 더 유니버시티 오브 웨스턴 온타리오 | 스태필로코쿠스 아우레우스의 철에 의해 조절되는 표면결정인자 IsdA, IsdB, 및 IsdC 기재 백신,조성물 및 방법 |
GB0526038D0 (en) * | 2005-12-21 | 2006-02-01 | Glaxosmithkline Biolog Sa | Immunogenic composition |
AU2007210170A1 (en) * | 2006-01-27 | 2007-08-09 | Merck Sharp & Dohme Corp. | Antigen-binding proteins targeting S. aureus ORF0657n |
CA2675992A1 (en) | 2007-01-24 | 2008-11-20 | Merck & Co., Inc. | Polypeptides for inducing a protective immune response against staphylococcus epidermidis |
EP1987836B1 (en) * | 2007-05-04 | 2011-12-21 | Martin Krönke | Protective staphylococcus aureus vaccine based on cell wall-associated proteins |
CN101679516B (zh) * | 2007-05-31 | 2013-11-13 | 默沙东公司 | 靶向金黄色葡萄球菌ORF0657n的抗原结合蛋白 |
EP2185195A2 (en) | 2007-08-16 | 2010-05-19 | Tripep Ab | Immunogen platform |
US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
WO2009029831A1 (en) | 2007-08-31 | 2009-03-05 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
WO2010014304A1 (en) | 2008-07-29 | 2010-02-04 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
JP2012509665A (ja) | 2008-11-26 | 2012-04-26 | メルク・シャープ・エンド・ドーム・コーポレイション | スタフィロコッカス・アウレウス(staphylococcusaureus)に対する防御免疫応答を誘導するポリペプチド |
KR101773368B1 (ko) | 2009-04-03 | 2017-08-31 | 유니버시티 오브 시카고 | 단백질 A(SpA) 변이체와 관련된 조성물 및 방법 |
SG175092A1 (en) | 2009-04-14 | 2011-11-28 | Novartis Ag | Compositions for immunising against staphylococcus aerus |
GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
JP2013506651A (ja) | 2009-09-30 | 2013-02-28 | ノバルティス アーゲー | Staphylococcus.aureus5型および8型莢膜多糖の結合体 |
PT2493498T (pt) | 2009-10-30 | 2017-05-24 | Glaxosmithkline Biologicals Sa | Purificação de sacáridos capsulares de staphylococcus aureus tipo 5 e tipo 8 |
GB0919690D0 (en) | 2009-11-10 | 2009-12-23 | Guy S And St Thomas S Nhs Foun | compositions for immunising against staphylococcus aureus |
EP2544709A4 (en) * | 2010-03-12 | 2014-01-08 | Univ Pennsylvania | METHODS FOR PREVENTING AND TREATING COLONIZATION, STAPHYLOCOCCUS AUREUS-INDUCED INFECTION AND DISEASE |
CN103037885B (zh) | 2010-07-02 | 2015-08-26 | 芝加哥大学 | 与蛋白A(SpA)变体相关的组合物和方法 |
EP2593133A4 (en) | 2010-07-13 | 2014-11-26 | Merck Sharp & Dohme | STAPHYLOCOCCUS AUREUS SURFACE PROTEIN SA1789 AND PROTECTIVE VACCINE BASED ON IT |
WO2012065034A1 (en) | 2010-11-12 | 2012-05-18 | Merck Sharp & Dohme Corp. | Enolase peptide conjugate vaccines against staphylococcus aureus |
US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
IN2014CN02152A (no) | 2011-09-01 | 2015-09-04 | Novartis Ag | |
WO2013066731A2 (en) | 2011-10-31 | 2013-05-10 | Merck Sharp & Dohme Corp. | Protective vaccine based on staphylococcus aureus sa2451 protein |
WO2014001325A1 (en) | 2012-06-27 | 2014-01-03 | F. Hoffmann-La Roche Ag | Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof |
RU2639287C2 (ru) | 2012-06-27 | 2017-12-20 | Ф. Хоффманн-Ля Рош Аг | Способ отбора и получения высокоселективных и мультиспецифичных нацеливающих групп с заданными свойствами, включающих по меньшей мере две различные связывающие группировки, и их применения |
US9376487B2 (en) | 2012-07-10 | 2016-06-28 | Merck Sharp & Dohme Corp. | Protective vaccine based on Staphylococcus aureus SA2493 protein |
US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
GB0014907D0 (en) * | 2000-06-20 | 2000-08-09 | Univ Sheffield | Antigenic polypeptides |
AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
EP2320233A1 (en) * | 2001-06-15 | 2011-05-11 | Inhibitex, Inc. | Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus |
ES2322338T3 (es) * | 2001-11-12 | 2009-06-19 | Novo Nordisk A/S | Purificacion de peptidos por medio de cromatografia de afinidad con iones metalicos. |
US20080050361A1 (en) * | 2004-10-25 | 2008-02-28 | Heinrichs David E | Staphylococcus aureas specific anti-infectives |
CA2637598A1 (en) * | 2006-01-18 | 2007-02-14 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
-
2004
- 2004-07-22 CA CA002532370A patent/CA2532370A1/en not_active Abandoned
- 2004-07-22 NZ NZ544542A patent/NZ544542A/en not_active IP Right Cessation
- 2004-07-22 WO PCT/US2004/023523 patent/WO2005009379A2/en active Application Filing
- 2004-07-22 BR BRPI0412799-4A patent/BRPI0412799A/pt not_active Application Discontinuation
- 2004-07-22 JP JP2006521226A patent/JP2007502101A/ja active Pending
- 2004-07-22 US US10/564,458 patent/US20060177462A1/en not_active Abandoned
- 2004-07-22 DK DK04778847.6T patent/DK1651166T3/da active
- 2004-07-22 KR KR1020067001610A patent/KR20060065643A/ko not_active Application Discontinuation
- 2004-07-22 AU AU2004258979A patent/AU2004258979B2/en not_active Ceased
- 2004-07-22 RU RU2006105498/13A patent/RU2337108C2/ru not_active IP Right Cessation
- 2004-07-22 MX MXPA06000854A patent/MXPA06000854A/es active IP Right Grant
- 2004-07-22 DE DE602004025579T patent/DE602004025579D1/de not_active Expired - Lifetime
- 2004-07-22 NZ NZ570750A patent/NZ570750A/en not_active IP Right Cessation
- 2004-07-22 EP EP04778847A patent/EP1651166B8/en not_active Expired - Lifetime
- 2004-07-22 AT AT04778847T patent/ATE457737T1/de active
- 2004-07-22 ES ES04778847T patent/ES2342778T3/es not_active Expired - Lifetime
- 2004-07-22 PL PL04778847T patent/PL1651166T3/pl unknown
- 2004-07-22 PT PT04778847T patent/PT1651166E/pt unknown
- 2004-07-22 SI SI200431389T patent/SI1651166T1/sl unknown
-
2005
- 2005-12-30 IS IS8213A patent/IS8213A/is unknown
-
2006
- 2006-01-19 IL IL173253A patent/IL173253A0/en unknown
- 2006-02-23 NO NO20060898A patent/NO20060898L/no not_active Application Discontinuation
-
2010
- 2010-04-26 HR HR20100240T patent/HRP20100240T1/hr unknown
- 2010-04-30 US US12/771,345 patent/US20100247561A1/en not_active Abandoned
- 2010-05-14 CY CY20101100419T patent/CY1110028T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP2007502101A (ja) | 2007-02-08 |
CY1110028T1 (el) | 2015-01-14 |
IS8213A (is) | 2005-12-30 |
IL173253A0 (en) | 2006-06-11 |
PL1651166T3 (pl) | 2010-08-31 |
AU2004258979B2 (en) | 2007-12-06 |
NZ570750A (en) | 2009-12-24 |
RU2337108C2 (ru) | 2008-10-27 |
MXPA06000854A (es) | 2006-03-30 |
CA2532370A1 (en) | 2005-02-03 |
WO2005009379A3 (en) | 2006-11-30 |
RU2006105498A (ru) | 2006-09-10 |
EP1651166B1 (en) | 2010-02-17 |
KR20060065643A (ko) | 2006-06-14 |
DE602004025579D1 (de) | 2010-04-01 |
HRP20100240T1 (hr) | 2010-09-30 |
ATE457737T1 (de) | 2010-03-15 |
NZ544542A (en) | 2009-01-31 |
EP1651166A2 (en) | 2006-05-03 |
EP1651166A4 (en) | 2008-03-05 |
EP1651166B8 (en) | 2010-05-19 |
AU2004258979A1 (en) | 2005-02-03 |
US20060177462A1 (en) | 2006-08-10 |
US20100247561A1 (en) | 2010-09-30 |
WO2005009379A2 (en) | 2005-02-03 |
PT1651166E (pt) | 2010-04-23 |
SI1651166T1 (sl) | 2010-06-30 |
ES2342778T3 (es) | 2010-07-14 |
BRPI0412799A (pt) | 2006-09-26 |
DK1651166T3 (da) | 2010-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20060898L (no) | Polypeptider til indusering av en beskyttende immunrespons mot Staphylococcus aurcus | |
WO2005079315A3 (en) | Polypeptides for inducing a protective immune response against staphylococcus aureus | |
WO2006033918A3 (en) | Polypeptides for inducing a protective immune response against staphylococcus aureus | |
WO2005115113A3 (en) | Polypeptides for inducing a protective immune response against staphylococcus aureus | |
WO2007001361A3 (en) | Polypeptides for inducing a protective immune response against staphylococcus aureus | |
WO2005086663A3 (en) | Polypeptides for inducing a protective immune response against staphlococcus aureus | |
WO2006078680A3 (en) | Polypeptides for inducing a protective immune response against staphylococcus aureus | |
IN2014CN02050A (no) | ||
BRPI0517493A (pt) | polinucleotìdeo isolado, promotor vetor de expressão, célula hospedeira e uso de um polinucleotìdeo | |
HUP0000302A2 (hu) | OB fúziós protein készítmények és módszerek | |
NO20063026L (no) | Antistoffer | |
DE60235761D1 (de) | Isoform des vegfs | |
ATE419359T1 (de) | Cdc27-homologe aus arabidopsis thaliana | |
ATE405654T1 (de) | Polypeptid mit verbesserter cytosin-deaminase- aktivität | |
ATE360701T1 (de) | Putrescin-n-methyltransferasepromotor | |
DK1344827T3 (da) | Frostbeskyttende proteiner fra basidiomycetes | |
UA102522C2 (ru) | Стойкое к грибкам трансгенное растение solanaceae | |
ATE196926T1 (de) | Gen grb3-3, variante und ihre verwendungen | |
ATE481420T1 (de) | Il-21-derivate | |
DE50213015D1 (de) | Lipase-varianten | |
WO2008140632A3 (en) | Polypeptides for inducing a protective immune response against staphylococcus epidermidis | |
HUP9700762A2 (hu) | Vaskötő fehérjét túltermelő stresszrezisztens transzgenikus növények | |
PH12013502021A1 (en) | Platelet aggregation inhibitor composition | |
WO2008115415A8 (en) | Polypeptides for inducing a protective immune response against staphylococcus epidermidis | |
WO2006121664A3 (en) | Polypeptides for inducing a protective immune response against staphylococcus aureus |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |