NZ536277A - Powder formulations containing tiotropium suitable for inhalation - Google Patents
Powder formulations containing tiotropium suitable for inhalationInfo
- Publication number
- NZ536277A NZ536277A NZ536277A NZ53627703A NZ536277A NZ 536277 A NZ536277 A NZ 536277A NZ 536277 A NZ536277 A NZ 536277A NZ 53627703 A NZ53627703 A NZ 53627703A NZ 536277 A NZ536277 A NZ 536277A
- Authority
- NZ
- New Zealand
- Prior art keywords
- inhalation
- physiologically acceptable
- acceptable excipient
- formulations containing
- powder formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02007634 | 2002-04-04 | ||
| PCT/EP2003/003253 WO2003084509A1 (en) | 2002-04-04 | 2003-03-28 | Powder formulations suitable for inhalation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ536277A true NZ536277A (en) | 2006-03-31 |
Family
ID=28685839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ536277A NZ536277A (en) | 2002-04-04 | 2003-03-28 | Powder formulations containing tiotropium suitable for inhalation |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6881422B2 (https=) |
| EP (1) | EP1494648B1 (https=) |
| JP (1) | JP2005526103A (https=) |
| KR (1) | KR101007151B1 (https=) |
| CN (1) | CN100360116C (https=) |
| AT (1) | ATE339951T1 (https=) |
| AU (1) | AU2003221531B2 (https=) |
| BR (1) | BR0308984A (https=) |
| CA (1) | CA2479919C (https=) |
| DE (1) | DE60308497T2 (https=) |
| DK (1) | DK1494648T3 (https=) |
| ES (1) | ES2272968T3 (https=) |
| IL (2) | IL163736A0 (https=) |
| MX (1) | MXPA04009583A (https=) |
| NZ (1) | NZ536277A (https=) |
| PL (1) | PL207752B1 (https=) |
| RU (1) | RU2004132222A (https=) |
| WO (1) | WO2003084509A1 (https=) |
| ZA (1) | ZA200406911B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE275391T1 (de) | 2000-10-12 | 2004-09-15 | Boehringer Ingelheim Pharma | Neue tiotropium-haltige inhalationspulver |
| US20030070679A1 (en) * | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
| US7244415B2 (en) * | 2002-03-28 | 2007-07-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | HFA suspension formulations of an anhydrate |
| DE10255387A1 (de) * | 2002-11-28 | 2004-06-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Tiotropium-haltige Pulverformulierung für die Inhalation |
| US7763280B2 (en) | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
| MXPA06004697A (es) | 2003-11-03 | 2006-07-05 | Boehringer Ingelheim Int | Procedimiento para la preparacion de sales de tiotropio, sles de tiotropio, asi como formulaciones medicamentosas que las contienen. |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2540633A1 (de) * | 1975-09-12 | 1977-04-28 | Boehringer Sohn Ingelheim | Neue quartaere n-beta-substituierte benzilsaeure-n-alkyl-nortropinester und verfahren zu deren herstellung |
| DE3211185A1 (de) * | 1982-03-26 | 1983-09-29 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue quartaere 6,11-dihydro-dibenzo-(b,e)-thiepin-11-n-alkyl- norscopinether und verfahren zu deren herstellung |
| DE3215493A1 (de) * | 1982-04-26 | 1983-11-03 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue zwischenprodukte, verfahren zu ihrer herstellung und ihre verwendung |
| US5610163A (en) * | 1989-09-16 | 1997-03-11 | Boehringer Ingelheim Gmbh | Esters of thienyl carboxylic acids and amino alcohols and their quaternization products |
| DE4108393A1 (de) * | 1991-03-15 | 1992-09-17 | Boehringer Ingelheim Kg | Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln |
| US5770738A (en) * | 1992-03-05 | 1998-06-23 | Boehringer Ingelheim Kg | Esters of bi- and tricyclic amino alcohols, their preparation and their use in pharmaceutical compositions |
| DE19515625C2 (de) * | 1995-04-28 | 1998-02-19 | Boehringer Ingelheim Kg | Verfahren zur Herstellung von enantiomerenreinen Tropasäureestern |
| FI105074B (fi) * | 1997-12-31 | 2000-06-15 | Leiras Oy | Farmaseuttisen formulaation valmistusmenetelmä |
| AU756852B2 (en) * | 1998-11-13 | 2003-01-23 | Jagotec Ag | Dry powder for inhalation |
| DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
| ATE275391T1 (de) * | 2000-10-12 | 2004-09-15 | Boehringer Ingelheim Pharma | Neue tiotropium-haltige inhalationspulver |
| UA75375C2 (en) * | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
| DE10064816A1 (de) * | 2000-12-22 | 2002-06-27 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung eines Anticholinergikums |
| US6506900B1 (en) * | 2001-01-31 | 2003-01-14 | Boehringer Ingelheim Pharma Ag | Process for preparing a scopine ester intermediate |
| US20030070679A1 (en) * | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
| US6482429B1 (en) * | 2001-06-20 | 2002-11-19 | Boehringer Ingelheim Pharmaceuticals, Inc. | Stable powder inhalation dosage formulation |
| DE10141377A1 (de) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Aufstreuverfahren zur Herstellung von Pulverformulierungen |
| DE10141376A1 (de) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Inhalationspulvern |
-
2003
- 2003-03-28 CN CNB038076438A patent/CN100360116C/zh not_active Expired - Fee Related
- 2003-03-28 IL IL16373603A patent/IL163736A0/xx unknown
- 2003-03-28 AU AU2003221531A patent/AU2003221531B2/en not_active Ceased
- 2003-03-28 DK DK03717247T patent/DK1494648T3/da active
- 2003-03-28 RU RU2004132222/15A patent/RU2004132222A/ru unknown
- 2003-03-28 DE DE60308497T patent/DE60308497T2/de not_active Expired - Lifetime
- 2003-03-28 KR KR1020047015822A patent/KR101007151B1/ko not_active Expired - Fee Related
- 2003-03-28 CA CA2479919A patent/CA2479919C/en not_active Expired - Fee Related
- 2003-03-28 NZ NZ536277A patent/NZ536277A/xx not_active IP Right Cessation
- 2003-03-28 ES ES03717247T patent/ES2272968T3/es not_active Expired - Lifetime
- 2003-03-28 EP EP03717247A patent/EP1494648B1/en not_active Expired - Lifetime
- 2003-03-28 PL PL371267A patent/PL207752B1/pl unknown
- 2003-03-28 AT AT03717247T patent/ATE339951T1/de active
- 2003-03-28 MX MXPA04009583A patent/MXPA04009583A/es active IP Right Grant
- 2003-03-28 BR BR0308984-3A patent/BR0308984A/pt not_active Application Discontinuation
- 2003-03-28 WO PCT/EP2003/003253 patent/WO2003084509A1/en not_active Ceased
- 2003-03-28 JP JP2003581749A patent/JP2005526103A/ja active Pending
- 2003-04-03 US US10/406,723 patent/US6881422B2/en not_active Expired - Lifetime
-
2004
- 2004-07-27 US US10/899,782 patent/US20050009857A1/en not_active Abandoned
- 2004-08-25 IL IL163736A patent/IL163736A/en not_active IP Right Cessation
- 2004-08-31 ZA ZA200406911A patent/ZA200406911B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL163736A0 (en) | 2005-12-18 |
| ES2272968T3 (es) | 2007-05-01 |
| BR0308984A (pt) | 2005-02-09 |
| EP1494648B1 (en) | 2006-09-20 |
| ATE339951T1 (de) | 2006-10-15 |
| HK1078795A1 (zh) | 2006-03-24 |
| US6881422B2 (en) | 2005-04-19 |
| IL163736A (en) | 2010-12-30 |
| DK1494648T3 (da) | 2006-12-27 |
| KR101007151B1 (ko) | 2011-01-13 |
| CA2479919A1 (en) | 2003-10-16 |
| AU2003221531B2 (en) | 2008-10-23 |
| CN1646099A (zh) | 2005-07-27 |
| RU2004132222A (ru) | 2005-10-10 |
| PL207752B1 (pl) | 2011-01-31 |
| CN100360116C (zh) | 2008-01-09 |
| MXPA04009583A (es) | 2005-01-11 |
| KR20040098049A (ko) | 2004-11-18 |
| PL371267A1 (en) | 2005-06-13 |
| AU2003221531A1 (en) | 2003-10-20 |
| US20050009857A1 (en) | 2005-01-13 |
| CA2479919C (en) | 2011-05-17 |
| JP2005526103A (ja) | 2005-09-02 |
| DE60308497D1 (de) | 2006-11-02 |
| EP1494648A1 (en) | 2005-01-12 |
| WO2003084509A1 (en) | 2003-10-16 |
| US20040029907A1 (en) | 2004-02-12 |
| DE60308497T2 (de) | 2007-02-22 |
| ZA200406911B (en) | 2006-07-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 28 MAR 2016 BY DENNEMEYER SA Effective date: 20130208 |
|
| LAPS | Patent lapsed |