NZ529544A - Encapsulation of nanosuspensions in liposomes and microspheres - Google Patents
Encapsulation of nanosuspensions in liposomes and microspheresInfo
- Publication number
- NZ529544A NZ529544A NZ529544A NZ52954402A NZ529544A NZ 529544 A NZ529544 A NZ 529544A NZ 529544 A NZ529544 A NZ 529544A NZ 52954402 A NZ52954402 A NZ 52954402A NZ 529544 A NZ529544 A NZ 529544A
- Authority
- NZ
- New Zealand
- Prior art keywords
- delivery system
- nanosuspension
- hydrophobic agent
- mvl
- liposome
- Prior art date
Links
- 239000006070 nanosuspension Substances 0.000 title claims abstract description 124
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- 229960000762 perphenazine Drugs 0.000 claims description 65
- 238000000034 method Methods 0.000 claims description 61
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Classifications
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- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
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- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
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- Dispersion Chemistry (AREA)
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- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29523301P | 2001-05-31 | 2001-05-31 | |
| PCT/US2002/017346 WO2002096368A2 (en) | 2001-05-31 | 2002-05-31 | Encapsulation of nanosuspensions in liposomes and microspheres |
Publications (1)
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| NZ529544A true NZ529544A (en) | 2006-11-30 |
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|---|---|---|---|
| NZ529544A NZ529544A (en) | 2001-05-31 | 2002-05-31 | Encapsulation of nanosuspensions in liposomes and microspheres |
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| Country | Link |
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| US (1) | US20030096000A1 (enExample) |
| EP (1) | EP1395243A2 (enExample) |
| JP (2) | JP2004532252A (enExample) |
| AU (2) | AU2002322024B2 (enExample) |
| CA (1) | CA2447990C (enExample) |
| IL (1) | IL158819A0 (enExample) |
| NZ (1) | NZ529544A (enExample) |
| WO (1) | WO2002096368A2 (enExample) |
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| US20050129753A1 (en) * | 2003-11-14 | 2005-06-16 | Gabizon Alberto A. | Method for drug loading in liposomes |
| US20060002994A1 (en) * | 2004-03-23 | 2006-01-05 | Thomas James L | Responsive liposomes for ultrasonic drug delivery |
| US20070059746A1 (en) * | 2005-09-14 | 2007-03-15 | Japan Science And Technology Agency | Substance carrier using hollow nanoparticle of hepatitis B virus protein and liposome, and method of introducing substance into cell |
| WO2009091531A2 (en) * | 2008-01-16 | 2009-07-23 | The General Hospital Corporation | Uniform-sized, multi-drug carrying and photosensitive liposomes for advance drug delivery |
| US20100260830A1 (en) * | 2009-04-08 | 2010-10-14 | Brian A Salvatore | Liposomal Formulations of Tocopheryl Amides |
| JP6043278B2 (ja) | 2010-04-09 | 2016-12-14 | パシラ ファーマシューティカルズ インコーポレーテッド | 多小胞リポソームを作製するための方法、大直径合成膜小胞を調製するための方法、および蒸発装置 |
| WO2012109387A1 (en) | 2011-02-08 | 2012-08-16 | Halozyme, Inc. | Composition and lipid formulation of a hyaluronan-degrading enzyme and the use thereof for treatment of benign prostatic hyperplasia |
| FR2987268B1 (fr) | 2012-02-28 | 2014-07-11 | Ammtek | Formulations liquides de sulfamides hypoglycemiants |
| RU2664700C2 (ru) | 2012-05-10 | 2018-08-21 | Пейнреформ Лтд. | Депо-составы местного анестетика и способы их получения |
| CA2926797A1 (en) * | 2013-10-14 | 2015-04-23 | Nanosphere Health Sciences, Llc | Nanoparticle compositions and methods as carriers of nutraceutical factors across cell membranes and biological barriers |
| DK3186281T3 (da) | 2014-08-28 | 2019-06-11 | Halozyme Inc | Kombinationsterapi med et hyaluronan-nedbrydende enzym og en immun-checkpoint-inhibitor |
| CA2970917C (en) | 2014-12-15 | 2019-09-17 | Nanosphere Health Sciences, Llc | Methods of treating inflammatory disorders and global inflammation with compositions comprising phospholipid nanoparticle encapsulations of nsaids |
| CA2979184C (en) | 2015-03-10 | 2020-09-08 | Nanosphere Health Sciences, Llc | Lipid nanoparticle compositions and methods as carriers of cannabinoids in standardized precision-metered dosage forms |
| US11344497B1 (en) | 2017-12-08 | 2022-05-31 | Quicksilver Scientific, Inc. | Mitochondrial performance enhancement nanoemulsion |
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-
2002
- 2002-05-31 IL IL15881902A patent/IL158819A0/xx unknown
- 2002-05-31 NZ NZ529544A patent/NZ529544A/en unknown
- 2002-05-31 WO PCT/US2002/017346 patent/WO2002096368A2/en not_active Ceased
- 2002-05-31 CA CA2447990A patent/CA2447990C/en not_active Expired - Fee Related
- 2002-05-31 US US10/161,969 patent/US20030096000A1/en not_active Abandoned
- 2002-05-31 JP JP2002592881A patent/JP2004532252A/ja not_active Withdrawn
- 2002-05-31 AU AU2002322024A patent/AU2002322024B2/en not_active Ceased
- 2002-05-31 EP EP02756110A patent/EP1395243A2/en not_active Withdrawn
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- 2008-08-08 AU AU2008203783A patent/AU2008203783A1/en not_active Abandoned
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2009
- 2009-08-07 JP JP2009185294A patent/JP2009256383A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20030096000A1 (en) | 2003-05-22 |
| AU2002322024B2 (en) | 2008-05-08 |
| JP2009256383A (ja) | 2009-11-05 |
| EP1395243A2 (en) | 2004-03-10 |
| CA2447990A1 (en) | 2002-12-05 |
| WO2002096368A2 (en) | 2002-12-05 |
| IL158819A0 (en) | 2004-05-12 |
| WO2002096368A3 (en) | 2003-07-10 |
| CA2447990C (en) | 2012-01-31 |
| JP2004532252A (ja) | 2004-10-21 |
| AU2008203783A1 (en) | 2008-08-28 |
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