NZ525380A - Non-fucosylated forms of Cripto and their use as tumor blocking agents - Google Patents
Non-fucosylated forms of Cripto and their use as tumor blocking agentsInfo
- Publication number
- NZ525380A NZ525380A NZ525380A NZ52538001A NZ525380A NZ 525380 A NZ525380 A NZ 525380A NZ 525380 A NZ525380 A NZ 525380A NZ 52538001 A NZ52538001 A NZ 52538001A NZ 525380 A NZ525380 A NZ 525380A
- Authority
- NZ
- New Zealand
- Prior art keywords
- seq
- cripto
- polypeptide
- amino acid
- cancer
- Prior art date
Links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23314800P | 2000-09-18 | 2000-09-18 | |
| PCT/US2001/029066 WO2002022808A2 (en) | 2000-09-18 | 2001-09-18 | Cripto mutant and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ525380A true NZ525380A (en) | 2008-06-30 |
Family
ID=22876077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ525380A NZ525380A (en) | 2000-09-18 | 2001-09-18 | Non-fucosylated forms of Cripto and their use as tumor blocking agents |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7604931B2 (https=) |
| EP (1) | EP1320604A2 (https=) |
| JP (1) | JP2004524810A (https=) |
| AU (2) | AU9272401A (https=) |
| CA (1) | CA2422814A1 (https=) |
| NZ (1) | NZ525380A (https=) |
| WO (1) | WO2002022808A2 (https=) |
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| US20090123470A1 (en) * | 2001-03-26 | 2009-05-14 | The Macfarlane Burnet Istitute For Medical Research And Public Health Ltd. | Antibodies Against Cancer |
| AUPR395801A0 (en) * | 2001-03-26 | 2001-04-26 | Austin Research Institute, The | Antibodies against cancer |
| US7582299B2 (en) | 2001-04-26 | 2009-09-01 | Biogen Idec Ma Inc. | Cripto-specific antibodies |
| PT1390389E (pt) * | 2001-04-26 | 2009-04-03 | Biogen Idec Inc | Anticorpos que bloqueiam o cripto e as utilizações dos mesmos |
| CA2539116C (en) | 2003-09-15 | 2014-11-18 | Research Development Foundation | Cripto antagonism of activin and tgf-b signaling |
| US20070122813A1 (en) * | 2003-10-03 | 2007-05-31 | David Salomon | Use of cripto-1 as a biomarker for neurodegenerative disease and method of inhibiting progression thereof |
| US7498298B2 (en) | 2003-11-06 | 2009-03-03 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
| KR20120064120A (ko) | 2004-06-01 | 2012-06-18 | 제넨테크, 인크. | 항체 약물 접합체 및 방법 |
| US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
| KR101270829B1 (ko) | 2004-09-23 | 2013-06-07 | 제넨테크, 인크. | 시스테인 유전자조작 항체 및 접합체 |
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| CN105246894A (zh) | 2012-12-21 | 2016-01-13 | 斯皮罗根有限公司 | 用于治疗增殖性和自身免疫疾病的非对称吡咯并苯并二氮杂卓二聚物 |
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| BR112016013258A2 (pt) | 2013-12-16 | 2018-01-16 | Genentech Inc | composto conjugado anticorpo-droga, composição farmacêutica, método para tratar câncer e kit |
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| JP7708662B2 (ja) | 2018-10-24 | 2025-07-15 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | コンジュゲート化された化学的分解誘導物質および使用方法 |
| EP3894427A1 (en) | 2018-12-10 | 2021-10-20 | Genentech, Inc. | Photocrosslinking peptides for site specific conjugation to fc-containing proteins |
| GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
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| CN117980327A (zh) | 2021-11-03 | 2024-05-03 | 杭州多禧生物科技有限公司 | 抗体的特异性偶联 |
| IT202200007580A1 (it) * | 2022-04-15 | 2023-10-15 | Consiglio Nazionale Ricerche | Vescicole lipidiche per l’uso nel trattamento terapeutico di tumori aggressivi |
| EP4637833A2 (en) | 2022-12-23 | 2025-10-29 | Genentech, Inc. | Cereblon degrader conjugates, and uses thereof |
| EP4698230A2 (en) | 2023-04-17 | 2026-02-25 | Peak Bio, Inc. | Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates |
| WO2026006689A2 (en) | 2024-06-28 | 2026-01-02 | Firefly Bio, Inc. | Bcl-xl degrader antibody conjugates and uses thereof |
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Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5256643A (en) * | 1990-05-29 | 1993-10-26 | The Government Of The United States | Human cripto protein |
| US5264557A (en) * | 1991-08-23 | 1993-11-23 | The United States Of America As Represented By The Department Of Health And Human Services | Polypeptide of a human cripto-related gene, CR-3 |
| KR19980703534A (ko) * | 1995-06-05 | 1998-11-05 | 벤슨로버트에이치 | 사람 크립틴 성장 인자 |
| DE69737457T2 (de) * | 1997-01-31 | 2007-11-29 | Genentech, Inc., South San Francisco | O-fukosyltransferase |
| JP2002505338A (ja) * | 1998-03-05 | 2002-02-19 | カイロン コーポレイション | 生物学的に活性な分子の血清半減期を増加するための方法 |
| IL125608A0 (en) * | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
-
2001
- 2001-09-18 CA CA002422814A patent/CA2422814A1/en not_active Abandoned
- 2001-09-18 JP JP2002527250A patent/JP2004524810A/ja active Pending
- 2001-09-18 WO PCT/US2001/029066 patent/WO2002022808A2/en not_active Ceased
- 2001-09-18 AU AU9272401A patent/AU9272401A/xx active Pending
- 2001-09-18 AU AU2001292724A patent/AU2001292724B2/en not_active Ceased
- 2001-09-18 EP EP01973111A patent/EP1320604A2/en not_active Withdrawn
- 2001-09-18 NZ NZ525380A patent/NZ525380A/en unknown
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2003
- 2003-03-17 US US10/390,566 patent/US7604931B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004524810A (ja) | 2004-08-19 |
| US20030232755A1 (en) | 2003-12-18 |
| EP1320604A2 (en) | 2003-06-25 |
| AU9272401A (en) | 2002-03-26 |
| AU2001292724B2 (en) | 2005-05-26 |
| WO2002022808A3 (en) | 2003-01-16 |
| CA2422814A1 (en) | 2002-03-21 |
| WO2002022808A2 (en) | 2002-03-21 |
| US7604931B2 (en) | 2009-10-20 |
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