NZ517017A - Targeting multimeric imaging agents through multiocus binding and improving the efficacy of in vivo contrast agents - Google Patents

Targeting multimeric imaging agents through multiocus binding and improving the efficacy of in vivo contrast agents

Info

Publication number
NZ517017A
NZ517017A NZ517017A NZ51701700A NZ517017A NZ 517017 A NZ517017 A NZ 517017A NZ 517017 A NZ517017 A NZ 517017A NZ 51701700 A NZ51701700 A NZ 51701700A NZ 517017 A NZ517017 A NZ 517017A
Authority
NZ
New Zealand
Prior art keywords
iem
tbm
iii
target
contrast agent
Prior art date
Application number
NZ517017A
Other languages
English (en)
Inventor
Randall B Lauffer
Thomas J Mcmurry
Stephane Dumas
Andrew Kolodziej
John Amedio
Peter Caravan
Zhaoda Zhang
Shrikumar Nair
Original Assignee
Epix Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epix Medical Inc filed Critical Epix Medical Inc
Publication of NZ517017A publication Critical patent/NZ517017A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052Small organic molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/12Macromolecular compounds
    • A61K49/124Macromolecular compounds dendrimers, dendrons, hyperbranched compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/12Macromolecular compounds
    • A61K49/126Linear polymers, e.g. dextran, inulin, PEG
    • A61K49/128Linear polymers, e.g. dextran, inulin, PEG comprising multiple complex or complex-forming groups, being either part of the linear polymeric backbone or being pending groups covalently linked to the linear polymeric backbone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/14Peptides, e.g. proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
NZ517017A 1999-07-29 2000-07-28 Targeting multimeric imaging agents through multiocus binding and improving the efficacy of in vivo contrast agents NZ517017A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14641499P 1999-07-29 1999-07-29
US16365099P 1999-11-04 1999-11-04
PCT/US2000/020536 WO2001008712A2 (en) 1999-07-29 2000-07-28 Targeting multimeric imaging agents through multilocus binding

Publications (1)

Publication Number Publication Date
NZ517017A true NZ517017A (en) 2004-05-28

Family

ID=26843871

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ517017A NZ517017A (en) 1999-07-29 2000-07-28 Targeting multimeric imaging agents through multiocus binding and improving the efficacy of in vivo contrast agents

Country Status (20)

Country Link
US (2) US6652835B1 (enExample)
EP (1) EP1210124A2 (enExample)
JP (2) JP2003505519A (enExample)
KR (1) KR20020057946A (enExample)
CN (2) CN1382062A (enExample)
AU (1) AU6386000A (enExample)
BR (1) BR0013171A (enExample)
CA (1) CA2384565A1 (enExample)
CZ (1) CZ2002343A3 (enExample)
EA (1) EA200200220A1 (enExample)
HK (1) HK1048952A1 (enExample)
HU (1) HUP0202635A3 (enExample)
IL (1) IL147854A0 (enExample)
IS (1) IS6241A (enExample)
MX (1) MXPA02001017A (enExample)
NO (1) NO20020474L (enExample)
NZ (1) NZ517017A (enExample)
PL (1) PL353336A1 (enExample)
WO (1) WO2001008712A2 (enExample)
YU (1) YU6502A (enExample)

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Also Published As

Publication number Publication date
KR20020057946A (ko) 2002-07-12
HK1048952A1 (zh) 2003-04-25
NO20020474L (no) 2002-03-27
WO2001008712A2 (en) 2001-02-08
US6652835B1 (en) 2003-11-25
CN1626246A (zh) 2005-06-15
NO20020474D0 (no) 2002-01-29
HUP0202635A2 (hu) 2002-11-28
CA2384565A1 (en) 2001-02-08
AU6386000A (en) 2001-02-19
HUP0202635A3 (en) 2006-03-28
BR0013171A (pt) 2002-05-28
IL147854A0 (en) 2002-08-14
PL353336A1 (en) 2003-11-17
EP1210124A2 (en) 2002-06-05
YU6502A (sh) 2005-06-10
IS6241A (is) 2002-01-18
JP2003505519A (ja) 2003-02-12
EA200200220A1 (ru) 2002-08-29
CZ2002343A3 (cs) 2002-08-14
CN1382062A (zh) 2002-11-27
WO2001008712A3 (en) 2002-03-14
MXPA02001017A (es) 2002-08-12
JP2003201258A (ja) 2003-07-18
US20040005274A1 (en) 2004-01-08

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