NZ505724A - Dihydroxyhexanoic acid derivatives and their pharmaceutical use - Google Patents

Dihydroxyhexanoic acid derivatives and their pharmaceutical use

Info

Publication number
NZ505724A
NZ505724A NZ505724A NZ50572499A NZ505724A NZ 505724 A NZ505724 A NZ 505724A NZ 505724 A NZ505724 A NZ 505724A NZ 50572499 A NZ50572499 A NZ 50572499A NZ 505724 A NZ505724 A NZ 505724A
Authority
NZ
New Zealand
Prior art keywords
acid derivatives
inflammation
dihydroxyhexanoic acid
pharmaceutical use
dihydroxyhexanoic
Prior art date
Application number
NZ505724A
Other languages
English (en)
Inventor
John Charles Kath
Matthew Frank Brown
Christopher Stanley Poss
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Priority to NZ523610A priority Critical patent/NZ523610A/en
Publication of NZ505724A publication Critical patent/NZ505724A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
NZ505724A 1998-02-05 1999-01-18 Dihydroxyhexanoic acid derivatives and their pharmaceutical use NZ505724A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ523610A NZ523610A (en) 1998-02-05 1999-01-18 A method of treating inflammatory conditions in a non-human mammal comprising administration of dihydroxyhexanoic acid derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7380198P 1998-02-05 1998-02-05
PCT/IB1999/000067 WO1999040061A2 (en) 1998-02-05 1999-01-18 Novel dihydroxyhexanoic acid derivatives

Publications (1)

Publication Number Publication Date
NZ505724A true NZ505724A (en) 2003-02-28

Family

ID=22115885

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ505724A NZ505724A (en) 1998-02-05 1999-01-18 Dihydroxyhexanoic acid derivatives and their pharmaceutical use

Country Status (36)

Country Link
EP (1) EP1051405B1 (cg-RX-API-DMAC7.html)
JP (1) JP3693916B2 (cg-RX-API-DMAC7.html)
KR (1) KR100385529B1 (cg-RX-API-DMAC7.html)
CN (1) CN1177834C (cg-RX-API-DMAC7.html)
AP (1) AP992A (cg-RX-API-DMAC7.html)
AR (1) AR016175A1 (cg-RX-API-DMAC7.html)
AT (1) ATE337307T1 (cg-RX-API-DMAC7.html)
AU (1) AU752407B2 (cg-RX-API-DMAC7.html)
BG (1) BG104726A (cg-RX-API-DMAC7.html)
BR (1) BR9907655A (cg-RX-API-DMAC7.html)
CA (1) CA2320388C (cg-RX-API-DMAC7.html)
DE (1) DE69932920T2 (cg-RX-API-DMAC7.html)
DZ (1) DZ2717A1 (cg-RX-API-DMAC7.html)
EA (1) EA003137B1 (cg-RX-API-DMAC7.html)
ES (1) ES2268847T3 (cg-RX-API-DMAC7.html)
GT (1) GT199900011A (cg-RX-API-DMAC7.html)
HR (1) HRP20000529B1 (cg-RX-API-DMAC7.html)
HU (1) HUP0100832A3 (cg-RX-API-DMAC7.html)
IL (1) IL137330A0 (cg-RX-API-DMAC7.html)
IS (1) IS5562A (cg-RX-API-DMAC7.html)
MA (1) MA26603A1 (cg-RX-API-DMAC7.html)
MY (1) MY133125A (cg-RX-API-DMAC7.html)
NO (1) NO20003965D0 (cg-RX-API-DMAC7.html)
NZ (1) NZ505724A (cg-RX-API-DMAC7.html)
OA (1) OA11448A (cg-RX-API-DMAC7.html)
PA (1) PA8467301A1 (cg-RX-API-DMAC7.html)
PE (1) PE20000243A1 (cg-RX-API-DMAC7.html)
PL (1) PL342817A1 (cg-RX-API-DMAC7.html)
SK (1) SK11262000A3 (cg-RX-API-DMAC7.html)
TN (1) TNSN99013A1 (cg-RX-API-DMAC7.html)
TR (1) TR200002248T2 (cg-RX-API-DMAC7.html)
TW (1) TW470744B (cg-RX-API-DMAC7.html)
UA (1) UA57824C2 (cg-RX-API-DMAC7.html)
WO (1) WO1999040061A2 (cg-RX-API-DMAC7.html)
YU (1) YU47100A (cg-RX-API-DMAC7.html)
ZA (1) ZA99873B (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1152752A1 (en) * 1999-01-29 2001-11-14 Millennium Pharmaceuticals, Inc. Methods for preventing graft rejection and ischemia-reperfusion injury
ATE397590T1 (de) * 1999-08-20 2008-06-15 Dow Agrosciences Llc Fungizide heterocyclische aromatische amide und deren zusammensetzungen, verfahren zu deren anwendung und herstellung
EP1498417A1 (en) * 2000-02-04 2005-01-19 Pfizer Products Inc. Heterocyclic amide derivatives
OA12174A (en) 2000-02-04 2006-05-09 Pfizer Prod Inc Heterocyclic amide derivatives.
US6740636B2 (en) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
US6746856B2 (en) 2000-08-09 2004-06-08 Pfizer Inc. Microbial conversion of bicyclic heteroaromatic compounds
MXPA03011784A (es) * 2001-06-22 2004-04-02 Pfizer Prod Inc Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros.
EP1269994A3 (en) * 2001-06-22 2003-02-12 Pfizer Products Inc. Pharmaceutical compositions comprising drug and concentration-enhancing polymers
CA2448825C (en) 2001-06-22 2009-08-11 Pfizer Products Inc. Pharmaceutical compositions of adsorbates of amorphous drug
DE10152351B4 (de) * 2001-10-18 2005-09-22 Schering Ag Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat
CA2474838C (en) 2002-02-01 2009-01-06 Pfizer Products Inc. Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
MXPA04011231A (es) * 2002-05-14 2005-01-25 Pfizer Prod Inc Metodos para fabricar derivados de dihidro-furan-2-ona.
BR0309930A (pt) 2002-05-14 2005-02-09 Pfizer Prod Inc Derivados do ácido dihidroxihexanóico, seus intermediários e métodos de produção
EP1539715A1 (en) * 2002-08-12 2005-06-15 Pfizer Products Inc. Crystal forms of quinoxaline-2-carboxylic acid 4-carbamoyl- 1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyl-octyl -amide
DE60329188D1 (de) 2002-08-12 2009-10-22 Bend Res Inc Arzneizubereitungen bestehend aus arzneimitteln in halb-geordneter form und polymeren
US20040087571A1 (en) * 2002-10-30 2004-05-06 Pfizer Inc Methods of using CCR1 antagonists as immunomodulatory agents
US20040097554A1 (en) * 2002-10-30 2004-05-20 Pfizer Inc Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents
WO2005011635A2 (en) 2003-08-04 2005-02-10 Pfizer Products Inc. Pharmaceutical compositions of adsorbates of amorphous drugs and lipophilic microphase-forming materials

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923864A (en) * 1987-12-15 1990-05-08 Pfizer Inc. Certain heterocyclic-hexanamides useful for treating hypertension
ES2180600T3 (es) * 1994-10-19 2003-02-16 Novartis Ag Eteres de isosteros substrato de aspartato proteasa antivirales.
DE19708106A1 (de) * 1997-02-28 1998-09-03 Bosch Gmbh Robert Einrichtung und Verfahren zur Information über Verkehrsstörungen

Also Published As

Publication number Publication date
CA2320388A1 (en) 1999-08-12
NO20003965L (cg-RX-API-DMAC7.html) 2000-10-03
KR100385529B1 (ko) 2003-05-27
GT199900011A (es) 2000-07-20
HUP0100832A3 (en) 2002-03-28
ZA99873B (en) 2000-08-04
DE69932920T2 (de) 2007-02-08
PL342817A1 (en) 2001-07-02
ATE337307T1 (de) 2006-09-15
DE69932920D1 (de) 2006-10-05
AU1778999A (en) 1999-08-23
HK1034969A1 (en) 2001-11-09
IS5562A (is) 2000-07-14
NO20003965D0 (no) 2000-08-04
MY133125A (en) 2007-10-31
DZ2717A1 (fr) 2003-09-01
HUP0100832A2 (hu) 2002-02-28
TW470744B (en) 2002-01-01
JP3693916B2 (ja) 2005-09-14
TR200002248T2 (tr) 2000-12-21
AP992A (en) 2001-08-06
AR016175A1 (es) 2001-06-20
AU752407B2 (en) 2002-09-19
OA11448A (en) 2003-11-18
CN1290255A (zh) 2001-04-04
ES2268847T3 (es) 2007-03-16
HRP20000529B1 (en) 2004-12-31
BG104726A (en) 2001-04-30
EA200000741A1 (ru) 2001-02-26
SK11262000A3 (sk) 2001-01-18
EA003137B1 (ru) 2003-02-27
CN1177834C (zh) 2004-12-01
JP2002502839A (ja) 2002-01-29
WO1999040061A3 (en) 1999-10-21
AP9901457A0 (en) 1999-03-31
KR20010040684A (ko) 2001-05-15
MA26603A1 (fr) 2004-12-20
WO1999040061A2 (en) 1999-08-12
PE20000243A1 (es) 2000-04-07
PA8467301A1 (es) 2000-05-24
IL137330A0 (en) 2001-07-24
HRP20000529A2 (en) 2001-08-31
EP1051405B1 (en) 2006-08-23
YU47100A (sh) 2002-11-15
CA2320388C (en) 2005-05-03
EP1051405A2 (en) 2000-11-15
BR9907655A (pt) 2000-10-24
UA57824C2 (uk) 2003-07-15
TNSN99013A1 (fr) 2005-11-10

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