NZ333737A - Parenteral formulations of taxane analogs comprising dimethylacetamide, polyethylene glycol and an aqueous lipid emulsion - Google Patents
Parenteral formulations of taxane analogs comprising dimethylacetamide, polyethylene glycol and an aqueous lipid emulsionInfo
- Publication number
- NZ333737A NZ333737A NZ333737A NZ33373797A NZ333737A NZ 333737 A NZ333737 A NZ 333737A NZ 333737 A NZ333737 A NZ 333737A NZ 33373797 A NZ33373797 A NZ 33373797A NZ 333737 A NZ333737 A NZ 333737A
- Authority
- NZ
- New Zealand
- Prior art keywords
- paclitaxel
- pharmaceutical composition
- dma
- peg
- pachtaxel
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/672,594 US5877205A (en) | 1996-06-28 | 1996-06-28 | Parenteral paclitaxel in a stable non-toxic formulation |
| PCT/US1997/011503 WO1998000128A1 (en) | 1996-06-28 | 1997-06-26 | Parenteral paclitaxel in a stable non-toxic formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ333737A true NZ333737A (en) | 2000-02-28 |
Family
ID=24699210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ333737A NZ333737A (en) | 1996-06-28 | 1997-06-26 | Parenteral formulations of taxane analogs comprising dimethylacetamide, polyethylene glycol and an aqueous lipid emulsion |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5877205A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0920311A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2000515132A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1165300C (cg-RX-API-DMAC7.html) |
| AU (1) | AU722617B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2259297C (cg-RX-API-DMAC7.html) |
| NO (1) | NO986165L (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ333737A (cg-RX-API-DMAC7.html) |
| WO (1) | WO1998000128A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| US6964946B1 (en) * | 1995-10-26 | 2005-11-15 | Baker Norton Pharmaceuticals, Inc. | Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same |
| US20030157187A1 (en) * | 1996-12-02 | 2003-08-21 | Angiotech Pharmaceuticals, Inc. | Compositions and methods for treating or preventing inflammatory diseases |
| US6727280B2 (en) * | 1997-01-07 | 2004-04-27 | Sonus Pharmaceuticals, Inc. | Method for treating colorectal carcinoma using a taxane/tocopherol formulation |
| US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| US20030087954A1 (en) * | 1997-01-07 | 2003-05-08 | Sonus Pharmaceuticals, Inc. | Method of treating bladder carcinoma using a Taxane/Tocopherol formulation |
| US20030105156A1 (en) * | 1997-01-07 | 2003-06-05 | Nagesh Palepu | Method for administration of a taxane/tocopherol formulation to enhance taxane therapeutic utility |
| US6045815A (en) * | 1997-08-15 | 2000-04-04 | Board Of Regents, The University Of Texas System | Parenteral pimaricin as treatment of systemic infections |
| US6844004B2 (en) | 1997-08-15 | 2005-01-18 | Board Of Regents, The University Of Texas System | Topical formulations of natamycin/pimaricin |
| PL201329B1 (pl) * | 1998-02-05 | 2009-03-31 | Novartis Ag | Preparat farmaceutyczny w postaci koncentratu infuzyjnego |
| IL131217A0 (en) * | 1998-03-10 | 2001-01-28 | Napro Biotherapeutics Inc | Novel methods and compositions for delivery of taxanes |
| KR19990075621A (ko) * | 1998-03-23 | 1999-10-15 | 임성주 | 경사 평판형 배양조 |
| KR100446959B1 (ko) * | 1998-04-02 | 2004-11-03 | 김종국 | 파클리탁셀주사제조성물 |
| US7030155B2 (en) * | 1998-06-05 | 2006-04-18 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| US6017948A (en) * | 1998-10-30 | 2000-01-25 | Supergen, Inc. | Water-miscible pharmaceutical compositions |
| WO2000037050A1 (en) * | 1998-12-22 | 2000-06-29 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Water-insoluble drug delivery system |
| US6040330A (en) * | 1999-01-08 | 2000-03-21 | Bionumerik Pharmaceuticals, Inc. | Pharmaceutical formulations of taxanes |
| US6121257A (en) * | 1999-03-31 | 2000-09-19 | Abbott Laboratories | Sulfamate containing macrocyclic immunomodulators |
| HK1049787B (en) | 1999-10-01 | 2014-07-25 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| SE9903831D0 (sv) | 1999-10-22 | 1999-10-22 | Astra Ab | Formulation of substituted benzimidazoles |
| US20040009229A1 (en) * | 2000-01-05 | 2004-01-15 | Unger Evan Charles | Stabilized nanoparticle formulations of camptotheca derivatives |
| PL350075A1 (en) * | 2000-02-02 | 2002-11-04 | Univ Florida State Res Found | Taxane formulations having improved solubility |
| AU2001258872C1 (en) | 2000-05-12 | 2005-05-26 | Samyang Biopharmaceuticals Corporation | Method for the preparation of polymeric micelle via phase separation of block copolymer |
| US7217770B2 (en) * | 2000-05-17 | 2007-05-15 | Samyang Corporation | Stable polymeric micelle-type drug composition and method for the preparation thereof |
| WO2002009695A1 (en) * | 2000-08-02 | 2002-02-07 | Atossa Healthcare, Inc. | Bimodal emulsions of taxanes and butyrate polyalcohol esters |
| US6919370B2 (en) * | 2000-11-28 | 2005-07-19 | Transform Pharmaceuticals, Inc. | Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof |
| JP2005504070A (ja) * | 2001-09-13 | 2005-02-10 | コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー | 化学塞栓用油性パクリタキセル組成物及び処方物並びにその製造方法 |
| WO2003045357A1 (en) * | 2001-11-27 | 2003-06-05 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
| BR0214277A (pt) * | 2001-11-30 | 2004-09-21 | Bristol Myers Squibb Co | Solvatos de paclitaxel |
| WO2003057128A2 (en) * | 2001-12-11 | 2003-07-17 | Dor Biopharma, Inc. | Lipid particles and suspensions and uses thereof |
| US20040213837A1 (en) * | 2002-08-05 | 2004-10-28 | Sankaram Mantripragada | Oil-core compositions for the sustained release of hydrophobic drugs |
| US20050129719A1 (en) * | 2003-12-15 | 2005-06-16 | Yu-Fang Hu | Concentrated emulsion formulation for silatecan |
| US20050220835A1 (en) * | 2004-03-30 | 2005-10-06 | Jayaraman Ramesh B | Agent eluting bioimplantable devices and polymer systems for their preparation |
| AU2005285953B2 (en) * | 2004-09-22 | 2011-01-20 | Nippon Kayaku Kabushiki Kaisha | Novel block copolymer, micelle preparation, and anticancer agent containing the same as active ingredient |
| CA2615939A1 (en) * | 2005-08-02 | 2007-02-08 | Miv Therapeutics Inc. | Microdevices comprising nanocapsules for controlled delivery of drugs and method of manufacturing same |
| US8323669B2 (en) * | 2006-03-28 | 2012-12-04 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of taxane |
| CN101448875A (zh) | 2006-05-18 | 2009-06-03 | 日本化药株式会社 | 鬼臼毒素类的高分子量结合体 |
| ES2584840T3 (es) * | 2006-10-03 | 2016-09-29 | Nippon Kayaku Kabushiki Kaisha | Compuesto de un derivado de resorcinol con un polímero |
| WO2008056596A1 (fr) | 2006-11-06 | 2008-05-15 | Nippon Kayaku Kabushiki Kaisha | Dérivé polymère d'un antagoniste métabolique d'acide nucléique |
| WO2008056654A1 (fr) | 2006-11-08 | 2008-05-15 | Nippon Kayaku Kabushiki Kaisha | Dérivé polymère d'un antagoniste métabolique d'acide nucléique |
| WO2009041570A1 (ja) | 2007-09-28 | 2009-04-02 | Nippon Kayaku Kabushiki Kaisha | ステロイド類の高分子結合体 |
| AR063111A1 (es) | 2007-10-03 | 2008-12-30 | Eriochem Sa | Una formulacion farmaceutica de taxano |
| KR101589582B1 (ko) * | 2008-03-18 | 2016-01-28 | 니폰 가야꾸 가부시끼가이샤 | 생리활성물질의 고분자량 결합체 |
| WO2009136572A1 (ja) | 2008-05-08 | 2009-11-12 | 日本化薬株式会社 | 葉酸若しくは葉酸誘導体の高分子結合体 |
| US8808749B2 (en) | 2009-05-15 | 2014-08-19 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of bioactive substance having hydroxy group |
| CN102038636B (zh) * | 2009-10-23 | 2014-08-13 | 天士力控股集团有限公司 | 一种含有螯合剂的紫杉烷类药物溶液及其制备方法 |
| CN102038634B (zh) * | 2009-10-23 | 2014-12-10 | 天士力控股集团有限公司 | 一种含有助溶剂的紫杉烷类药物溶液及其制备方法 |
| CN102038635A (zh) * | 2009-10-23 | 2011-05-04 | 天津天士力集团有限公司 | 一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法 |
| TWI438009B (zh) * | 2010-02-19 | 2014-05-21 | Teikoku Pharma Usa Inc | 紫杉烷前－乳劑調配物及其製造與使用之方法 |
| AU2011248449B2 (en) | 2010-05-03 | 2016-09-15 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| TWI472340B (zh) * | 2010-11-10 | 2015-02-11 | Tasly Holding Group Co Ltd | Taxanes containing solution and a preparation method of the co-solvent |
| CN103221054A (zh) | 2010-11-17 | 2013-07-24 | 日本化药株式会社 | 新的胞苷类代谢拮抗剂的高分子衍生物 |
| JP5711378B2 (ja) * | 2011-09-11 | 2015-04-30 | 日本化薬株式会社 | ブロック共重合体の製造方法 |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| CN109464382B (zh) * | 2019-01-08 | 2020-10-09 | 四川大学 | 一种可注射的高载药量的紫杉醇凝胶及其制备方法和应用 |
| JP2024537910A (ja) * | 2021-10-21 | 2024-10-16 | カシーヴ バイオサイエンシズ，リミテッド・ライアビリティ・カンパニー | 安定した希釈準備済みカルフィルゾミブ組成物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2698543B1 (fr) * | 1992-12-02 | 1994-12-30 | Rhone Poulenc Rorer Sa | Nouvelles compositions à base de taxoides. |
| US5430057A (en) * | 1993-09-30 | 1995-07-04 | Board Of Regents, The University Of Texas System | Parenteral busulfan for treatment of malignant disease |
| US5597829A (en) * | 1994-05-09 | 1997-01-28 | Bionumerik Pharmaceuticals, Inc. | Lactone stable formulation of camptothecin and methods for uses thereof |
| TW372967B (en) * | 1994-12-27 | 1999-11-01 | Kanebo Ltd | 1,4 benzoxazine derivative, pharmaceutical composition containing the same and use thereof |
-
1996
- 1996-06-28 US US08/672,594 patent/US5877205A/en not_active Expired - Fee Related
-
1997
- 1997-06-26 WO PCT/US1997/011503 patent/WO1998000128A1/en not_active Ceased
- 1997-06-26 CN CNB971969345A patent/CN1165300C/zh not_active Expired - Fee Related
- 1997-06-26 NZ NZ333737A patent/NZ333737A/en unknown
- 1997-06-26 CA CA002259297A patent/CA2259297C/en not_active Expired - Fee Related
- 1997-06-26 JP JP10504432A patent/JP2000515132A/ja not_active Ceased
- 1997-06-26 EP EP97933246A patent/EP0920311A4/en not_active Withdrawn
- 1997-06-26 AU AU36478/97A patent/AU722617B2/en not_active Ceased
-
1998
- 1998-12-28 NO NO986165A patent/NO986165L/no unknown
-
1999
- 1999-03-01 US US09/259,533 patent/US6107333A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU722617B2 (en) | 2000-08-10 |
| JP2000515132A (ja) | 2000-11-14 |
| NO986165D0 (no) | 1998-12-28 |
| EP0920311A4 (en) | 2001-10-04 |
| NO986165L (no) | 1999-02-25 |
| CA2259297C (en) | 2003-12-16 |
| CA2259297A1 (en) | 1998-01-08 |
| US6107333A (en) | 2000-08-22 |
| EP0920311A1 (en) | 1999-06-09 |
| AU3647897A (en) | 1998-01-21 |
| WO1998000128A1 (en) | 1998-01-08 |
| CN1228022A (zh) | 1999-09-08 |
| US5877205A (en) | 1999-03-02 |
| CN1165300C (zh) | 2004-09-08 |
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Legal Events
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| RENW | Renewal (renewal fees accepted) | ||
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Free format text: THE OWNER HAS BEEN CORRECTED TO 857962, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, 201 WEST 7TH STREET, AUSTIN, TEXAS 78701, US Effective date: 20140808 |