NZ263006A - Chromatographic methods for purifying interleukin-10 - Google Patents

Chromatographic methods for purifying interleukin-10

Info

Publication number
NZ263006A
NZ263006A NZ263006A NZ26300694A NZ263006A NZ 263006 A NZ263006 A NZ 263006A NZ 263006 A NZ263006 A NZ 263006A NZ 26300694 A NZ26300694 A NZ 26300694A NZ 263006 A NZ263006 A NZ 263006A
Authority
NZ
New Zealand
Prior art keywords
protein
dimers
acetylated
contained
chromatography
Prior art date
Application number
NZ263006A
Other languages
English (en)
Inventor
Gary Vellekamp
Susan Cannon-Carlson
John Tang
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NZ263006A publication Critical patent/NZ263006A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5428IL-10
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ263006A 1993-03-05 1994-03-03 Chromatographic methods for purifying interleukin-10 NZ263006A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/026,942 US5328989A (en) 1993-03-05 1993-03-05 Purification of human interleukin-10 from a cell culture medium

Publications (1)

Publication Number Publication Date
NZ263006A true NZ263006A (en) 1997-07-27

Family

ID=21834690

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ263006A NZ263006A (en) 1993-03-05 1994-03-03 Chromatographic methods for purifying interleukin-10

Country Status (12)

Country Link
US (2) US5328989A (ja)
EP (1) EP0688335A1 (ja)
JP (1) JP2802168B2 (ja)
KR (1) KR0178304B1 (ja)
CN (1) CN1119018A (ja)
AU (1) AU683458B2 (ja)
CA (1) CA2157358C (ja)
FI (1) FI954047A (ja)
HU (1) HU218263B (ja)
IL (1) IL108837A (ja)
NZ (1) NZ263006A (ja)
WO (1) WO1994020525A1 (ja)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6106823A (en) * 1991-01-16 2000-08-22 Schering Corporation Treatment of neoplastic disease with interleukin-10
US5328989A (en) * 1993-03-05 1994-07-12 Schering-Plough Purification of human interleukin-10 from a cell culture medium
CA2144576A1 (en) * 1994-03-17 1995-09-18 Donald W. Nicholson A single step purification of recombinant human interleukin-5
US6022536A (en) * 1995-08-09 2000-02-08 Schering Corporation Combined use of interleukin 10 and cyclosporin for immunosuppression therapy
US7361331B2 (en) * 1996-10-18 2008-04-22 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Plant bioreactors
AU732306B2 (en) * 1997-10-14 2001-04-12 Chugai Seiyaku Kabushiki Kaisha Potentiator for antibody against lymphoid tumor
JP2003535565A (ja) * 1998-12-31 2003-12-02 アーチ ディベロプメント コーポレイション 新生物疾患の治療に有用な組換え単純ヘルペスウイルス
CA2379823A1 (en) * 1999-07-16 2001-01-25 Human Genome Sciences, Inc. Real-time, in situ biomanufacturing process monitoring and control in response to ir spectroscopy
CA2380111A1 (en) * 1999-08-03 2001-02-08 Smith & Nephew, Inc. Controlled release implantable devices
TWI248365B (en) * 1999-08-23 2006-02-01 Chugai Pharmaceutical Co Ltd HM1.24 antigen expression potentiators
US7931897B2 (en) * 2001-02-07 2011-04-26 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for hematopoietic tumors
US20050152902A1 (en) * 2001-06-05 2005-07-14 Advanced Biotherapy, Inc. Treatment of diabetic retinopathy
DK2261230T3 (en) * 2002-09-11 2017-06-12 Chugai Pharmaceutical Co Ltd Method of Protein Purification.
US20050276807A1 (en) * 2004-06-15 2005-12-15 Advanced Biotherapy, Inc. Treatment of acne
WO2013058762A1 (en) * 2011-10-21 2013-04-25 Tanvex Biologics Corp. Separation of acetylated proteins from unacetylated proteins
US20140228539A1 (en) * 2011-10-21 2014-08-14 Tanvex Biologics Corp. Separation of acetylated proteins from unacetylated proteins
CN103360461B (zh) * 2012-03-31 2016-12-14 中国科学技术大学 一种人il-12亲和纯化层析柱、其制备方法及利用其纯化重组人il-12的方法
US9943568B2 (en) 2013-04-18 2018-04-17 Armo Biosciences, Inc. Methods of using pegylated interleukin-10 for treating cancer
EP3010527B1 (en) 2013-06-17 2018-08-08 Armo Biosciences, Inc. Method for assessing protein identity and stability
EP3038642A4 (en) 2013-08-30 2017-01-18 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
WO2015070060A1 (en) 2013-11-11 2015-05-14 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US10293043B2 (en) 2014-06-02 2019-05-21 Armo Biosciences, Inc. Methods of lowering serum cholesterol
MX2017004838A (es) 2014-10-14 2017-10-16 Armo Biosciences Inc Composiciones de interleucina-15 y usos de estas.
US10143726B2 (en) 2014-10-22 2018-12-04 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
WO2016126615A1 (en) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
KR20180020141A (ko) 2015-05-28 2018-02-27 아르모 바이오사이언시스 인코포레이티드 암 치료에 사용되는 peg화된 인터류킨-10
WO2017035232A1 (en) 2015-08-25 2017-03-02 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
CN106222222B (zh) * 2016-08-08 2019-10-29 湖北医药学院 一种重组人白血病抑制因子的制备方法
CN114599665A (zh) 2019-08-16 2022-06-07 应用分子转运公司 组合物、制剂及白细胞介素产生和纯化
CN112501126B (zh) * 2020-12-03 2023-04-07 康立泰生物医药(青岛)有限公司 一种cho-dhfr+细胞株及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3110611A1 (de) * 1981-03-18 1982-10-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen "mitogene der leukozyten und des entzuendungsgewebes:natuerliche leukopoetine zur selektiven anregung der teilung und differenzierung von leukozyten"
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
US4751078A (en) * 1985-07-03 1988-06-14 Nagabhushan Tattanahalli L Process for the purification of gamma interferon
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
US5227302A (en) * 1988-12-20 1993-07-13 Ludwig Institute For Cancer Research DNA encoding platelet derived endothelial cell growth factor (PD-ECGF)
US5055555A (en) * 1989-01-05 1991-10-08 Helmut Sassenfeld Purification of G-CSF
IL94878A (en) * 1989-06-28 2003-01-12 Schering Corp Cytokine synthesis inhibitory factor, antagonists thereof and methods of using same
US5231012A (en) * 1989-06-28 1993-07-27 Schering Corporation Nucleic acids encoding cytokine synthesis inhibitory factor (interleukin-10)
US5368854A (en) * 1992-08-20 1994-11-29 Schering Corporation Use of IL-10 to treat inflammatory bowel disease
US5328989A (en) * 1993-03-05 1994-07-12 Schering-Plough Purification of human interleukin-10 from a cell culture medium

Also Published As

Publication number Publication date
FI954047A0 (fi) 1995-08-29
EP0688335A1 (en) 1995-12-27
IL108837A0 (en) 1994-06-24
AU6351594A (en) 1994-09-26
KR960701084A (ko) 1996-02-24
CA2157358A1 (en) 1994-09-15
CN1119018A (zh) 1996-03-20
JP2802168B2 (ja) 1998-09-24
CA2157358C (en) 2000-05-16
HU9502586D0 (en) 1995-10-30
HUT73102A (en) 1996-06-28
AU683458B2 (en) 1997-11-13
IL108837A (en) 2001-01-11
US5710251A (en) 1998-01-20
WO1994020525A1 (en) 1994-09-15
JPH08503227A (ja) 1996-04-09
US5328989A (en) 1994-07-12
KR0178304B1 (ko) 1999-04-01
FI954047A (fi) 1995-08-29
HU218263B (hu) 2000-06-28

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