NZ247922A - Formamidinoalkane bisphosphonate derivatives and pharmaceutical compositions - Google Patents
Formamidinoalkane bisphosphonate derivatives and pharmaceutical compositionsInfo
- Publication number
- NZ247922A NZ247922A NZ247922A NZ24792293A NZ247922A NZ 247922 A NZ247922 A NZ 247922A NZ 247922 A NZ247922 A NZ 247922A NZ 24792293 A NZ24792293 A NZ 24792293A NZ 247922 A NZ247922 A NZ 247922A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compound
- formula
- pharmaceutically acceptable
- lower alkyl
- hydrogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH198492 | 1992-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ247922A true NZ247922A (en) | 1995-07-26 |
Family
ID=4223192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ247922A NZ247922A (en) | 1992-06-22 | 1993-06-18 | Formamidinoalkane bisphosphonate derivatives and pharmaceutical compositions |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5413994A (en:Method) |
| EP (1) | EP0576396A1 (en:Method) |
| JP (1) | JPH0656857A (en:Method) |
| KR (1) | KR940005279A (en:Method) |
| AU (1) | AU665090B2 (en:Method) |
| CA (1) | CA2098780A1 (en:Method) |
| FI (1) | FI932837A7 (en:Method) |
| HU (1) | HU214628B (en:Method) |
| IL (1) | IL106080A (en:Method) |
| MX (1) | MX9303722A (en:Method) |
| NO (1) | NO932283L (en:Method) |
| NZ (1) | NZ247922A (en:Method) |
| PH (1) | PH30103A (en:Method) |
| TW (1) | TW258729B (en:Method) |
| ZA (1) | ZA934424B (en:Method) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01109057A (ja) * | 1987-10-23 | 1989-04-26 | Fanuc Ltd | デジタイジング方法 |
| DE4223940A1 (de) * | 1992-07-21 | 1994-01-27 | Boehringer Mannheim Gmbh | Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| ES2368824T3 (es) * | 1998-03-27 | 2011-11-22 | Oregon Health & Science University | Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos. |
| IL149357A0 (en) * | 2000-09-07 | 2002-11-10 | Bayer Ag | Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binding agents |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2408523C3 (de) * | 1974-02-22 | 1978-05-18 | Benckiser-Knapsack Gmbh, 6802 Ladenburg | Verfahren zur Verhütung von Harzausscheidungen bei der Papierherstellung |
| DE2500209B2 (de) * | 1975-01-03 | 1977-03-03 | Benckiser-Knapsack Gmbh, 6802 Ladenburg | Verfahren und mittel zur verhuetung von harzausscheidungen bei der papierherstellung |
| DE2530139C3 (de) * | 1975-04-30 | 1979-06-21 | Joh. A. Benckiser Gmbh, 6700 Ludwigshafen | N-Acyl-1 -aminoalkan-1,1 -diphosphonsäuren, deren Herstellung und Verwendung |
| US4094782A (en) * | 1975-04-30 | 1978-06-13 | Joh. A. Benckiser | N-acyl-1-amino alkane-1,1-diphosphonic acid compounds and compositions for and method of using same |
| GB8521380D0 (en) * | 1985-08-28 | 1985-10-02 | Amersham Int Plc | Bone-seeking complexes of technetium-99m |
| DE3822650A1 (de) * | 1988-07-05 | 1990-02-01 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| DE3930130A1 (de) * | 1989-09-09 | 1991-03-21 | Boehringer Mannheim Gmbh | Neue amidingruppen-haltige diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| DK0531253T3 (da) * | 1991-08-27 | 1997-01-27 | Ciba Geigy Ag | N-substituerede aminomethandiphosphonsyrer |
| GB2267494B (en) * | 1992-06-02 | 1995-09-20 | Ciba Geigy Ag | Trisamidodithionodiphosphates |
| DE4223940A1 (de) * | 1992-07-21 | 1994-01-27 | Boehringer Mannheim Gmbh | Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
-
1993
- 1993-05-22 TW TW082104051A patent/TW258729B/zh active
- 1993-06-09 US US08/074,234 patent/US5413994A/en not_active Expired - Fee Related
- 1993-06-14 EP EP93810423A patent/EP0576396A1/de not_active Withdrawn
- 1993-06-18 NZ NZ247922A patent/NZ247922A/en unknown
- 1993-06-18 FI FI932837A patent/FI932837A7/fi not_active Application Discontinuation
- 1993-06-18 CA CA002098780A patent/CA2098780A1/en not_active Abandoned
- 1993-06-21 ZA ZA934424A patent/ZA934424B/xx unknown
- 1993-06-21 KR KR1019930011295A patent/KR940005279A/ko not_active Withdrawn
- 1993-06-21 HU HU9301830A patent/HU214628B/hu not_active IP Right Cessation
- 1993-06-21 JP JP5149052A patent/JPH0656857A/ja active Pending
- 1993-06-21 MX MX9303722A patent/MX9303722A/es unknown
- 1993-06-21 NO NO932283A patent/NO932283L/no unknown
- 1993-06-21 PH PH46387A patent/PH30103A/en unknown
- 1993-06-21 IL IL106080A patent/IL106080A/xx not_active IP Right Cessation
- 1993-06-22 AU AU41430/93A patent/AU665090B2/en not_active Ceased
-
1995
- 1995-02-07 US US08/384,882 patent/US5457094A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU665090B2 (en) | 1995-12-14 |
| KR940005279A (ko) | 1994-03-21 |
| FI932837L (fi) | 1993-12-23 |
| ZA934424B (en) | 1994-01-17 |
| US5457094A (en) | 1995-10-10 |
| JPH0656857A (ja) | 1994-03-01 |
| NO932283D0 (no) | 1993-06-21 |
| CA2098780A1 (en) | 1993-12-23 |
| HU214628B (hu) | 1998-04-28 |
| IL106080A (en) | 1997-06-10 |
| HUT64356A (en) | 1993-12-28 |
| AU4143093A (en) | 1993-12-23 |
| NO932283L (no) | 1993-12-23 |
| MX9303722A (es) | 1994-01-31 |
| PH30103A (en) | 1996-12-27 |
| US5413994A (en) | 1995-05-09 |
| IL106080A0 (en) | 1993-10-20 |
| FI932837A0 (fi) | 1993-06-18 |
| EP0576396A1 (de) | 1993-12-29 |
| TW258729B (en:Method) | 1995-10-01 |
| HU9301830D0 (en) | 1993-09-28 |
| FI932837A7 (fi) | 1993-12-23 |
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