NZ247922A - Formamidinoalkane bisphosphonate derivatives and pharmaceutical compositions - Google Patents
Formamidinoalkane bisphosphonate derivatives and pharmaceutical compositionsInfo
- Publication number
- NZ247922A NZ247922A NZ247922A NZ24792293A NZ247922A NZ 247922 A NZ247922 A NZ 247922A NZ 247922 A NZ247922 A NZ 247922A NZ 24792293 A NZ24792293 A NZ 24792293A NZ 247922 A NZ247922 A NZ 247922A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compound
- formula
- pharmaceutically acceptable
- lower alkyl
- hydrogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH198492 | 1992-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ247922A true NZ247922A (en) | 1995-07-26 |
Family
ID=4223192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ247922A NZ247922A (en) | 1992-06-22 | 1993-06-18 | Formamidinoalkane bisphosphonate derivatives and pharmaceutical compositions |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5413994A (en:Method) |
| EP (1) | EP0576396A1 (en:Method) |
| JP (1) | JPH0656857A (en:Method) |
| KR (1) | KR940005279A (en:Method) |
| AU (1) | AU665090B2 (en:Method) |
| CA (1) | CA2098780A1 (en:Method) |
| FI (1) | FI932837L (en:Method) |
| HU (1) | HU214628B (en:Method) |
| IL (1) | IL106080A (en:Method) |
| MX (1) | MX9303722A (en:Method) |
| NO (1) | NO932283L (en:Method) |
| NZ (1) | NZ247922A (en:Method) |
| PH (1) | PH30103A (en:Method) |
| TW (1) | TW258729B (en:Method) |
| ZA (1) | ZA934424B (en:Method) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01109057A (ja) * | 1987-10-23 | 1989-04-26 | Fanuc Ltd | デジタイジング方法 |
| DE4223940A1 (de) * | 1992-07-21 | 1994-01-27 | Boehringer Mannheim Gmbh | Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| WO1999049870A1 (en) * | 1998-03-27 | 1999-10-07 | Oregon Health Sciences University | Vitamin d and its analogs in the treatment of tumors and other hyperproliferative disorders |
| JP2004508373A (ja) * | 2000-09-07 | 2004-03-18 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | 環式および非環式アミジンおよびプロゲステロン受容体結合剤として使用するためのそれらを含有する医薬組成物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2500209B2 (de) * | 1975-01-03 | 1977-03-03 | Benckiser-Knapsack Gmbh, 6802 Ladenburg | Verfahren und mittel zur verhuetung von harzausscheidungen bei der papierherstellung |
| DE2408523C3 (de) * | 1974-02-22 | 1978-05-18 | Benckiser-Knapsack Gmbh, 6802 Ladenburg | Verfahren zur Verhütung von Harzausscheidungen bei der Papierherstellung |
| DE2530139C3 (de) * | 1975-04-30 | 1979-06-21 | Joh. A. Benckiser Gmbh, 6700 Ludwigshafen | N-Acyl-1 -aminoalkan-1,1 -diphosphonsäuren, deren Herstellung und Verwendung |
| US4094782A (en) * | 1975-04-30 | 1978-06-13 | Joh. A. Benckiser | N-acyl-1-amino alkane-1,1-diphosphonic acid compounds and compositions for and method of using same |
| GB8521380D0 (en) * | 1985-08-28 | 1985-10-02 | Amersham Int Plc | Bone-seeking complexes of technetium-99m |
| DE3822650A1 (de) * | 1988-07-05 | 1990-02-01 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| DE3930130A1 (de) * | 1989-09-09 | 1991-03-21 | Boehringer Mannheim Gmbh | Neue amidingruppen-haltige diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| TW207543B (en:Method) * | 1991-08-27 | 1993-06-11 | Ciba Geigy Ag | |
| GB2267494B (en) * | 1992-06-02 | 1995-09-20 | Ciba Geigy Ag | Trisamidodithionodiphosphates |
| DE4223940A1 (de) * | 1992-07-21 | 1994-01-27 | Boehringer Mannheim Gmbh | Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
-
1993
- 1993-05-22 TW TW082104051A patent/TW258729B/zh active
- 1993-06-09 US US08/074,234 patent/US5413994A/en not_active Expired - Fee Related
- 1993-06-14 EP EP93810423A patent/EP0576396A1/de not_active Withdrawn
- 1993-06-18 NZ NZ247922A patent/NZ247922A/en unknown
- 1993-06-18 FI FI932837A patent/FI932837L/fi not_active Application Discontinuation
- 1993-06-18 CA CA002098780A patent/CA2098780A1/en not_active Abandoned
- 1993-06-21 MX MX9303722A patent/MX9303722A/es unknown
- 1993-06-21 ZA ZA934424A patent/ZA934424B/xx unknown
- 1993-06-21 NO NO932283A patent/NO932283L/no unknown
- 1993-06-21 JP JP5149052A patent/JPH0656857A/ja active Pending
- 1993-06-21 PH PH46387A patent/PH30103A/en unknown
- 1993-06-21 HU HU9301830A patent/HU214628B/hu not_active IP Right Cessation
- 1993-06-21 IL IL106080A patent/IL106080A/xx not_active IP Right Cessation
- 1993-06-21 KR KR1019930011295A patent/KR940005279A/ko not_active Withdrawn
- 1993-06-22 AU AU41430/93A patent/AU665090B2/en not_active Ceased
-
1995
- 1995-02-07 US US08/384,882 patent/US5457094A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5457094A (en) | 1995-10-10 |
| FI932837A7 (fi) | 1993-12-23 |
| IL106080A0 (en) | 1993-10-20 |
| FI932837A0 (fi) | 1993-06-18 |
| PH30103A (en) | 1996-12-27 |
| AU4143093A (en) | 1993-12-23 |
| FI932837L (fi) | 1993-12-23 |
| JPH0656857A (ja) | 1994-03-01 |
| NO932283L (no) | 1993-12-23 |
| US5413994A (en) | 1995-05-09 |
| HU214628B (hu) | 1998-04-28 |
| TW258729B (en:Method) | 1995-10-01 |
| NO932283D0 (no) | 1993-06-21 |
| CA2098780A1 (en) | 1993-12-23 |
| AU665090B2 (en) | 1995-12-14 |
| MX9303722A (es) | 1994-01-31 |
| HUT64356A (en) | 1993-12-28 |
| ZA934424B (en) | 1994-01-17 |
| KR940005279A (ko) | 1994-03-21 |
| HU9301830D0 (en) | 1993-09-28 |
| EP0576396A1 (de) | 1993-12-29 |
| IL106080A (en) | 1997-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5393748A (en) | Methylenebisphosphonic acid derivatives | |
| US5438048A (en) | Methylenebisphosphonic acid derivatives | |
| EP0570380B1 (en) | Novel methylenebisphosphonic acid derivatives | |
| EP0524023A1 (en) | Trifluoromethylbenzylphosphonates useful in treating osteoporosis | |
| AU657018B2 (en) | Guanidinoalkyl-1, 1-bisphosphonic acid derivatives, process for their preparation and their use | |
| US5162310A (en) | Phenylaliphatylaminoalkanediphosphonic acids | |
| AU6510890A (en) | Gem-diphosphonic acids, a process for the preparation thereof and pharmaceutical compositions containing them | |
| US5457094A (en) | Heterocyclic amidines useful for treating diseases associated with calcium metabolism | |
| EP0531253B1 (en) | N-substituted aminomethanediphosphonic acids | |
| US5134134A (en) | Unsaturated aminodicarboxylic acid derivatives | |
| IE903452A1 (en) | Phosphonic acid, a method for its manufacture, and its use as an active ingredient in medicines | |
| AU652384B2 (en) | Novel benzoheterocyclylalkylaminoalkanediphosphonic acids |