NO932283L - Farmasoeytiske preparater inneholden-de amidinforbindelser og nye ami-diner - Google Patents

Farmasoeytiske preparater inneholden-de amidinforbindelser og nye ami-diner

Info

Publication number
NO932283L
NO932283L NO932283A NO932283A NO932283L NO 932283 L NO932283 L NO 932283L NO 932283 A NO932283 A NO 932283A NO 932283 A NO932283 A NO 932283A NO 932283 L NO932283 L NO 932283L
Authority
NO
Norway
Prior art keywords
compounds
pharmaceutical preparations
formula
lower alkyl
preparations containing
Prior art date
Application number
NO932283A
Other languages
English (en)
Other versions
NO932283D0 (no
Inventor
Knut A Jaeggi
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO932283D0 publication Critical patent/NO932283D0/no
Publication of NO932283L publication Critical patent/NO932283L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Det blir beskrevet forbindelser med formel I, hvor R, R1 og R2 uavhengig av hverandre står for hydrogen eller lavalkyl; eller R og R^ sammen står for en bivalent rest -( CH2)m-X-(CH2 }n , a) hvor m og n uavhengig av hverandre er l til 6, b) hvor summen av m og n er 2 til 7 og c) hvor X står for en gruppe -CH2-, -CH-CH-, -N(R3)- eller S(0)p-, hvor R3 står for hydrogen, lavalkyl, fenyl-lavalkyl eller lavalkanoyl og p står for O til 2; og q står for O til 6; eller et farmasøytisk anvendbart salt av dette, og minst ett farmasøytisk anvendbart bæremateriale, foruten nye for- bindelser med formel I, fremgangsmåter for fremstilling av disse, og anvendelsen av forbindelsene med formel I, for terapeutisk behandling av det human eller animalske legeme eller for fremstilling av farmasøytiske preparater. Forbindelsene har verdifulle farmasøytiske egenskaper og er spesielt virksomme som regulatorer av kalsium- stoffskiftet. De blir fremstilt på en kjent måte.
NO932283A 1992-06-22 1993-06-21 Farmasoeytiske preparater inneholden-de amidinforbindelser og nye ami-diner NO932283L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH198492 1992-06-22

Publications (2)

Publication Number Publication Date
NO932283D0 NO932283D0 (no) 1993-06-21
NO932283L true NO932283L (no) 1993-12-23

Family

ID=4223192

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932283A NO932283L (no) 1992-06-22 1993-06-21 Farmasoeytiske preparater inneholden-de amidinforbindelser og nye ami-diner

Country Status (15)

Country Link
US (2) US5413994A (no)
EP (1) EP0576396A1 (no)
JP (1) JPH0656857A (no)
KR (1) KR940005279A (no)
AU (1) AU665090B2 (no)
CA (1) CA2098780A1 (no)
FI (1) FI932837A (no)
HU (1) HU214628B (no)
IL (1) IL106080A (no)
MX (1) MX9303722A (no)
NO (1) NO932283L (no)
NZ (1) NZ247922A (no)
PH (1) PH30103A (no)
TW (1) TW258729B (no)
ZA (1) ZA934424B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01109057A (ja) * 1987-10-23 1989-04-26 Fanuc Ltd デジタイジング方法
DE4223940A1 (de) * 1992-07-21 1994-01-27 Boehringer Mannheim Gmbh Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
CA2326117A1 (en) * 1998-03-27 1999-10-07 Oregon Health Sciences University Vitamin d and its analogs in the treatment of tumors and other hyperproliferative disorders
AU8852901A (en) * 2000-09-07 2002-03-22 Bayer Corporation Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binding agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2500209B2 (de) * 1975-01-03 1977-03-03 Benckiser-Knapsack Gmbh, 6802 Ladenburg Verfahren und mittel zur verhuetung von harzausscheidungen bei der papierherstellung
DE2408523C3 (de) * 1974-02-22 1978-05-18 Benckiser-Knapsack Gmbh, 6802 Ladenburg Verfahren zur Verhütung von Harzausscheidungen bei der Papierherstellung
DE2530139C3 (de) * 1975-04-30 1979-06-21 Joh. A. Benckiser Gmbh, 6700 Ludwigshafen N-Acyl-1 -aminoalkan-1,1 -diphosphonsäuren, deren Herstellung und Verwendung
US4094782A (en) * 1975-04-30 1978-06-13 Joh. A. Benckiser N-acyl-1-amino alkane-1,1-diphosphonic acid compounds and compositions for and method of using same
GB8521380D0 (en) * 1985-08-28 1985-10-02 Amersham Int Plc Bone-seeking complexes of technetium-99m
DE3822650A1 (de) * 1988-07-05 1990-02-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE3930130A1 (de) * 1989-09-09 1991-03-21 Boehringer Mannheim Gmbh Neue amidingruppen-haltige diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
ATE147396T1 (de) * 1991-08-27 1997-01-15 Ciba Geigy Ag N-substituierte aminomethandiphosphonsäuren
GB2267494B (en) * 1992-06-02 1995-09-20 Ciba Geigy Ag Trisamidodithionodiphosphates
DE4223940A1 (de) * 1992-07-21 1994-01-27 Boehringer Mannheim Gmbh Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
NO932283D0 (no) 1993-06-21
CA2098780A1 (en) 1993-12-23
AU665090B2 (en) 1995-12-14
IL106080A (en) 1997-06-10
TW258729B (no) 1995-10-01
EP0576396A1 (de) 1993-12-29
MX9303722A (es) 1994-01-31
NZ247922A (en) 1995-07-26
HU214628B (hu) 1998-04-28
IL106080A0 (en) 1993-10-20
FI932837A0 (fi) 1993-06-18
ZA934424B (en) 1994-01-17
US5457094A (en) 1995-10-10
HUT64356A (en) 1993-12-28
KR940005279A (ko) 1994-03-21
HU9301830D0 (en) 1993-09-28
FI932837A (fi) 1993-12-23
PH30103A (en) 1996-12-27
US5413994A (en) 1995-05-09
AU4143093A (en) 1993-12-23
JPH0656857A (ja) 1994-03-01

Similar Documents

Publication Publication Date Title
IL93360A (en) Bactericidal/permeability increasing protein or biologically active analogs thereof and pharmaceutical compositions containing them
MX9203543A (es) Medicamento.
ES2055911T3 (es) Compuesto farmaceutico adelgazante.
NZ314207A (en) 1-(2-Oxoacetyl)-piperidine-2-carboxylic acid derivatives as multi drug resistant cancer cell sensitizers
DK0430045T3 (da) Ascorbinsyretocopherylphosphatdiestere til hæmning af Maillards reaktion
DK570689D0 (da) Praeparater og forbindelser
AU2868689A (en) Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia
MD1560G2 (ro) Compuşi ciclici, compoziţii farmaceutice pe baza lor şi metode de tratament al infecţiilor sau bolilor provocate de retrovirusuri
ATE130312T1 (de) Polypeptid mit sich wiederholenden zelladhäsiven hauptsequenzen.
NO932283L (no) Farmasoeytiske preparater inneholden-de amidinforbindelser og nye ami-diner
FR2597097B1 (fr) Derives de benzothiazepine-1, 5, leur preparation et leur application en therapeutique
DK248886D0 (da) Spiro-imidazolidin-forbindelser og farmaceutiske praeparater indeholdende disse
ZA908696B (en) Hetero cyclic pharmaceutical compounds preparation and use
MY110092A (en) Butyric acid derivatives
CA2038025A1 (en) Optically active alkylenedioxybenzene derivatives and their use in therapy
HUT49283A (en) Process for production of medical compositions applicable for treatment of peptical ulcer
DE3162053D1 (en) N-acyl peptide compounds, processes for the preparation thereof and pharmaceutical compositions containing them
DK0505400T3 (da) N-substituerede naphthalimider, deres fremstilling og anvendelse
HUP9802941A2 (hu) Görcsoldó hatású 4-es helyzetben diszubsztituált aminocsoportot tartalmazó 1-ar(alk)il-imidazolin-2-onok, eljárás ezek előállítására, ezeket tartalmazó gyógyászati készítmények és alkalmazásuk
RU94042230A (ru) Производные 1,3,4-оксадиазол-2-(3н)-она, их приготовление и применение в терапии
ES2170183T3 (es) Benzoilguanidinas sustituidas con 4-fluoroalquilo, procedimiento para su preparacion, su utilizacion como medicamento, asi como medicamento que las contiene.
NO933558L (no) Benzimidazoler, legemidler inneholdende disse forbindelser, og fremgangsmåte for deres fremstilling
GB8501535D0 (en) Chemical compounds
DK0571511T3 (da) Nye urea- og thioureaforbindelser, deres fremstilling og terapeutiske anvendelse
FR2413383A1 (fr) Derives de type 5,6-dihydro-prostacycline, leurs procedes de preparation et leurs applications therapeutiques