NZ245757A - Biphenyl-substituted quinoline derivatives and pharmaceutical compositions thereof - Google Patents

Biphenyl-substituted quinoline derivatives and pharmaceutical compositions thereof

Info

Publication number
NZ245757A
NZ245757A NZ245757A NZ24575793A NZ245757A NZ 245757 A NZ245757 A NZ 245757A NZ 245757 A NZ245757 A NZ 245757A NZ 24575793 A NZ24575793 A NZ 24575793A NZ 245757 A NZ245757 A NZ 245757A
Authority
NZ
New Zealand
Prior art keywords
compound
biphenyl
oxy
tetrazol
pharmaceutically acceptable
Prior art date
Application number
NZ245757A
Other languages
English (en)
Inventor
Denis Evan Ryono
John Lloyd
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of NZ245757A publication Critical patent/NZ245757A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ245757A 1992-02-14 1993-01-26 Biphenyl-substituted quinoline derivatives and pharmaceutical compositions thereof NZ245757A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83778292A 1992-02-14 1992-02-14

Publications (1)

Publication Number Publication Date
NZ245757A true NZ245757A (en) 1995-09-26

Family

ID=25275409

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ245757A NZ245757A (en) 1992-02-14 1993-01-26 Biphenyl-substituted quinoline derivatives and pharmaceutical compositions thereof

Country Status (16)

Country Link
EP (1) EP0556060A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH05286939A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR930017891A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1044243C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU656454B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2089185A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI930621A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU217627B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL104623A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9300742A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO930520L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ245757A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL172241B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2122540C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW297025B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA93531B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5767129A (en) * 1995-08-24 1998-06-16 Warner-Lambert Company Substituted quinolines and isoquinolines as calcium channel blockers, their preparation and the use thereof
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
EP1411929B1 (en) 2001-01-26 2011-05-11 Chugai Seiyaku Kabushiki Kaisha Malonyl-coa decarboxylase inhibitors useful as metabolic modulators
DE60219595T2 (de) 2001-01-26 2008-01-10 Chugai Seiyaku K.K. Verfahren zur behandlung von erkrankungen mit malonyl coa-decarboxylase-inhibitoren
WO2002064136A2 (en) 2001-01-26 2002-08-22 Chugai Seiyaku Kabushiki Kaisha Malonyl-coa decarboxylase inhibitors useful as metabolic modulators
PT1370260E (pt) 2001-02-20 2011-02-01 Chugai Pharmaceutical Co Ltd Azóis como inibidores da malonil-coa-descarboxilase úteis como moduladores metabólicos
US7709510B2 (en) 2001-02-20 2010-05-04 Chugai Seiyaku Kabushiki Kaisha Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
RU2201753C1 (ru) * 2002-03-12 2003-04-10 Нестерук Владимир Викторович Фармацевтическая композиция, обладающая диуретическим, дегидратирующим и гипотензивным действием
PE20040950A1 (es) * 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
US7786145B2 (en) 2003-08-01 2010-08-31 Chugai Seiyaku Kabushiki Kaisha Cyanoguanidine-based azole compounds useful as malonyl-CoA decarboxylase inhibitors
WO2005011670A1 (en) 2003-08-01 2005-02-10 Chugai Seiyaku Kabushiki Kaisha Heterocyclic compounds useful as malonyl-coa decarboxylase inhibitors
JP4648317B2 (ja) 2003-08-01 2011-03-09 中外製薬株式会社 マロニル−CoAデカルボキシラーゼ阻害剤として有用なピペリジン化合物
ATE375810T1 (de) 2003-08-01 2007-11-15 Chugai Pharmaceutical Co Ltd Cyanoamid-verbindungen als nützliche malonyl-coa decarboxylase-hemmer
TWI374883B (en) * 2004-08-16 2012-10-21 Theravance Inc Crystalline form of a biphenyl compound
NZ566537A (en) 2005-09-30 2010-10-29 Pulmagen Therapeutics Asthma L Quinolines and their therapeutic use
GB0519969D0 (en) * 2005-09-30 2005-11-09 Argenta Discovery Ltd Quinoline compounds
PL2139881T3 (pl) * 2007-04-04 2012-04-30 Pulmagen Therapeutics Asthma Ltd Chinoliny i ich zastosowanie terapeutyczne

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
IE903911A1 (en) * 1989-11-20 1991-05-22 Ici Plc Diazine derivatives
US5049565A (en) * 1990-12-07 1991-09-17 Merck & Co., Inc. Microbial transformation process for preparing anti-hypertensive products
GB9102727D0 (en) * 1991-02-08 1991-03-27 Ici Plc Pharmaceutical agent
US5157040A (en) * 1991-04-05 1992-10-20 Merck & Co., Inc. Substituted quinolines as angiotensin ii antagonists

Also Published As

Publication number Publication date
CN1075720A (zh) 1993-09-01
EP0556060A1 (en) 1993-08-18
PL172241B1 (pl) 1997-08-29
CA2089185A1 (en) 1993-08-15
NO930520D0 (no) 1993-02-12
AU656454B2 (en) 1995-02-02
HUT69694A (en) 1995-09-28
ZA93531B (en) 1993-08-26
AU3299193A (en) 1993-08-19
IL104623A0 (en) 1993-06-10
CN1044243C (zh) 1999-07-21
RU2122540C1 (ru) 1998-11-27
FI930621A7 (fi) 1993-08-15
JPH05286939A (ja) 1993-11-02
NO930520L (no) 1993-08-16
FI930621A0 (fi) 1993-02-12
KR930017891A (ko) 1993-09-20
HU9300386D0 (en) 1993-04-28
HU217627B (hu) 2000-03-28
PL297713A1 (en) 1993-08-23
IL104623A (en) 1996-12-05
TW297025B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1997-02-01
MX9300742A (es) 1993-09-01

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