NZ226475A - Soluble hcd4 (t4) t-lymphocyte surface glycoprotein that binds hiv gp120 envelope protein - Google Patents

Soluble hcd4 (t4) t-lymphocyte surface glycoprotein that binds hiv gp120 envelope protein

Info

Publication number
NZ226475A
NZ226475A NZ226475A NZ22647588A NZ226475A NZ 226475 A NZ226475 A NZ 226475A NZ 226475 A NZ226475 A NZ 226475A NZ 22647588 A NZ22647588 A NZ 22647588A NZ 226475 A NZ226475 A NZ 226475A
Authority
NZ
New Zealand
Prior art keywords
human
protein
fragment
hiv
amino acid
Prior art date
Application number
NZ226475A
Other languages
English (en)
Inventor
Rebecca Hussey
Ellis Reinherz
Linda K Clayton
Joseph Sodroski
Neil Richardson
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/217,475 external-priority patent/US5109123A/en
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of NZ226475A publication Critical patent/NZ226475A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ226475A 1987-10-08 1988-10-06 Soluble hcd4 (t4) t-lymphocyte surface glycoprotein that binds hiv gp120 envelope protein NZ226475A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10618587A 1987-10-08 1987-10-08
US14431388A 1988-01-14 1988-01-14
US20658588A 1988-06-14 1988-06-14
US07/217,475 US5109123A (en) 1988-06-14 1988-07-11 Alteration of ability of soluble CD4 fragments to bind HIV

Publications (1)

Publication Number Publication Date
NZ226475A true NZ226475A (en) 1991-03-26

Family

ID=27493499

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ226475A NZ226475A (en) 1987-10-08 1988-10-06 Soluble hcd4 (t4) t-lymphocyte surface glycoprotein that binds hiv gp120 envelope protein

Country Status (9)

Country Link
EP (1) EP0400010A1 (fr)
JP (1) JPH03504234A (fr)
AU (1) AU2614888A (fr)
DK (1) DK87490A (fr)
ES (1) ES2012129A6 (fr)
GR (1) GR1000850B (fr)
IL (1) IL87902A0 (fr)
NZ (1) NZ226475A (fr)
WO (1) WO1989003222A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637677A (en) 1987-07-16 1997-06-10 The Trustees Of The University Of Pennsylvania Biologically active compounds and methods of constructing and using the same
ZA887365B (en) * 1987-10-02 1990-05-30 Genentech Inc Adheson variants
AU623924B2 (en) * 1988-07-22 1992-05-28 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Cytotoxic agent against specific virus infection
US5206353A (en) * 1988-07-23 1993-04-27 The United States Of America As Represented By The Department Of Health And Human Services CD-4/cytotoxic gene fusions
EP0408372A1 (fr) * 1989-07-13 1991-01-16 Smithkline Beecham Corporation Thérapie antivirale
KR927003613A (ko) * 1989-08-23 1992-12-18 더 제너랄 호스피탈 코오퍼레이숀 비-인체 영장동물의 cd4폴리텝타이드, 글리코실화할 수 있는 인체 cd4분자, 그것의 단편, 그것의 융합 단백질, 유전자 서열 및 그것의 용도
US5614612A (en) * 1990-03-09 1997-03-25 Haigwood; Nancy L. Purified gp120 compositions retaining natural conformation
JPH0725794B2 (ja) * 1990-03-23 1995-03-22 呉羽化学工業株式会社 新規なペプチド
WO1992004914A1 (fr) * 1990-09-14 1992-04-02 The Trustees Of The University Of Pennsylvania Production de peptides bioactifs sur la base de la structure des immunoglobulines
EP1340769B1 (fr) 1991-02-08 2005-02-09 Progenics Pharmaceuticals, Inc. Chimères de CD4-gamma2 et de CD4-IgG2
AU1438592A (en) * 1991-02-08 1992-09-07 Progenics Pharmaceuticals, Inc. Cd4-gamma1 and cd4-igg1 chimeras
US7070991B2 (en) 1991-02-08 2006-07-04 Progenics Pharmaceuticals, Inc. Cells expressing a CD4-IgG2 chimeric heterotetramer
US5234905A (en) * 1991-02-22 1993-08-10 University Of Colorado Foundation, Inc. Soluble CD4 molecules modified to prolong circulating half-life
EP0510483A1 (fr) * 1991-04-22 1992-10-28 Boehringer Ingelheim Pharmaceuticals Inc. Procédé pour la détection des virus
AU2221600A (en) 1998-12-31 2000-07-31 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
DK1141315T3 (da) 1998-12-31 2008-05-19 Novartis Vaccines & Diagnostic Modificerede HIV Env-polypeptider
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
AU2487300A (en) 1998-12-31 2000-07-31 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
WO2003004620A2 (fr) 2001-07-05 2003-01-16 Chiron, Corporation Polynucleotides codant des polypeptides de type c du vih antigeniques, polypeptides et leurs utilisations
EP1427806A4 (fr) 2001-08-31 2006-04-26 Chiron Corp Polynucleotides codant des polypeptides de type b du vih antigeniques, polypeptides et leurs utilisations
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
WO2014150748A2 (fr) 2013-03-15 2014-09-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Domaines cd4 humains uniques stabilisés et protéines de fusion
WO2017055522A1 (fr) 2015-09-29 2017-04-06 Academisch Medisch Centrum Protéines env stabilisées du vih

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU616639B2 (en) * 1986-08-21 1991-11-07 Trustees Of Columbia University In The City Of New York, The Dna encoding the t cell surface protein t4 and use of fragments of t4 in the treatment of aids
NZ226414A (en) * 1987-10-02 1992-07-28 Genentech Inc Cd4 peptide adhesion variants and their preparation and use

Also Published As

Publication number Publication date
EP0400010A1 (fr) 1990-12-05
ES2012129A6 (es) 1990-03-01
IL87902A0 (en) 1989-03-31
JPH03504234A (ja) 1991-09-19
AU2614888A (en) 1989-05-02
DK87490A (da) 1990-06-08
WO1989003222A1 (fr) 1989-04-20
GR1000850B (el) 1993-02-17
DK87490D0 (da) 1990-04-06

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