IL87902A0 - Soluble human cd4 fragments and applications thereof - Google Patents

Soluble human cd4 fragments and applications thereof

Info

Publication number
IL87902A0
IL87902A0 IL87902A IL8790288A IL87902A0 IL 87902 A0 IL87902 A0 IL 87902A0 IL 87902 A IL87902 A IL 87902A IL 8790288 A IL8790288 A IL 8790288A IL 87902 A0 IL87902 A0 IL 87902A0
Authority
IL
Israel
Prior art keywords
fragments
applications
soluble human
soluble
human
Prior art date
Application number
IL87902A
Other languages
English (en)
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/217,475 external-priority patent/US5109123A/en
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of IL87902A0 publication Critical patent/IL87902A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL87902A 1987-10-08 1988-10-04 Soluble human cd4 fragments and applications thereof IL87902A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10618587A 1987-10-08 1987-10-08
US14431388A 1988-01-14 1988-01-14
US20658588A 1988-06-14 1988-06-14
US07/217,475 US5109123A (en) 1988-06-14 1988-07-11 Alteration of ability of soluble CD4 fragments to bind HIV

Publications (1)

Publication Number Publication Date
IL87902A0 true IL87902A0 (en) 1989-03-31

Family

ID=27493499

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87902A IL87902A0 (en) 1987-10-08 1988-10-04 Soluble human cd4 fragments and applications thereof

Country Status (9)

Country Link
EP (1) EP0400010A1 (xx)
JP (1) JPH03504234A (xx)
AU (1) AU2614888A (xx)
DK (1) DK87490A (xx)
ES (1) ES2012129A6 (xx)
GR (1) GR1000850B (xx)
IL (1) IL87902A0 (xx)
NZ (1) NZ226475A (xx)
WO (1) WO1989003222A1 (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637677A (en) 1987-07-16 1997-06-10 The Trustees Of The University Of Pennsylvania Biologically active compounds and methods of constructing and using the same
ZA887365B (en) * 1987-10-02 1990-05-30 Genentech Inc Adheson variants
US5206353A (en) * 1988-07-23 1993-04-27 The United States Of America As Represented By The Department Of Health And Human Services CD-4/cytotoxic gene fusions
AU623924B2 (en) * 1988-07-22 1992-05-28 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Cytotoxic agent against specific virus infection
EP0408372A1 (en) * 1989-07-13 1991-01-16 Smithkline Beecham Corporation Anti-viral therapy
JPH05500611A (ja) * 1989-08-23 1993-02-12 ザ・ジェネラル・ホスピタル・コーポレーション 非ヒト霊長類ｃｄ４ポリペプチド、グリコシル化可能なヒトｃｄ４分子、その断片、その融合タンパク質、その遺伝子配列および使用
US5614612A (en) * 1990-03-09 1997-03-25 Haigwood; Nancy L. Purified gp120 compositions retaining natural conformation
JPH0725794B2 (ja) * 1990-03-23 1995-03-22 呉羽化学工業株式会社 新規なペプチド
ATE229974T1 (de) * 1990-09-14 2003-01-15 Univ Pennsylvania Design von bioaktiven peptiden auf der basis von immunglobulin strukturen
WO1992013559A1 (en) * 1991-02-08 1992-08-20 Progenics Pharmaceuticals, Inc. CD4-GAMMA1 AND CD4-IgG1 CHIMERAS
JP3670276B2 (ja) 1991-02-08 2005-07-13 プロゲニクス・ファーマスーティカルズ、インコーポレイテッド ＣＤ４― ガンマ・２キメラ及びＣＤ４ ― ＩｇＧ２・キメラ
US7070991B2 (en) 1991-02-08 2006-07-04 Progenics Pharmaceuticals, Inc. Cells expressing a CD4-IgG2 chimeric heterotetramer
US5234905A (en) * 1991-02-22 1993-08-10 University Of Colorado Foundation, Inc. Soluble CD4 molecules modified to prolong circulating half-life
EP0510483A1 (en) * 1991-04-22 1992-10-28 Boehringer Ingelheim Pharmaceuticals Inc. Method for the detection of viruses
EP1141313A2 (en) 1998-12-31 2001-10-10 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
AU2596600A (en) 1998-12-31 2000-07-31 Chiron Corporation Modified hiv env polypeptides
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
CA2358385C (en) 1998-12-31 2013-08-06 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
EP1411770A4 (en) 2001-07-05 2006-05-10 Chiron Corp POLYNUCLEOTIDES CODING FOR ANTIGENIC C-TYPE HIV POLYPEPTIDES, POLYPEPTIDES AND THEIR USE
WO2003020876A2 (en) 2001-08-31 2003-03-13 Chiron Corporation Polynucleotides encoding antigenic hiv type b polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
CN105209057B (zh) 2013-03-15 2020-03-27 美国卫生和人力服务部 稳定的人单cd4结构域和融合蛋白
WO2017055522A1 (en) 2015-09-29 2017-04-06 Academisch Medisch Centrum Stabilized env proteins of hiv

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3751751T2 (de) * 1986-08-21 1996-10-17 Univ Columbia Für das t-zell oberflächenprotein t4 kodierende dna und verwendung von t4-fragmenten bei der behandlung von aids
PT88641B (pt) * 1987-10-02 1993-04-30 Genentech Inc Metodo para a preparacao de uma variante de adesao

Also Published As

Publication number Publication date
DK87490D0 (da) 1990-04-06
JPH03504234A (ja) 1991-09-19
NZ226475A (en) 1991-03-26
WO1989003222A1 (en) 1989-04-20
DK87490A (da) 1990-06-08
AU2614888A (en) 1989-05-02
EP0400010A1 (en) 1990-12-05
ES2012129A6 (es) 1990-03-01
GR1000850B (el) 1993-02-17

Similar Documents

Publication Publication Date Title
IL87902A0 (en) Soluble human cd4 fragments and applications thereof
US5031245B1 (en) Gloves their manufacture and use
IL89885A0 (en) Fibrin-collagen tissue equivalents and their production
AR243910A1 (es) Particulas polimericas con nucleo y cubierta y el procedimiento para prepararlas.
EP0269393A3 (en) Absorbent products and their manufacture
EP0268498A3 (en) Absorbent products and their manufacture
NZ224046A (en) Hiv antigenic peptide fragments and their use
IL88814A0 (en) Soluble polyimidesiloxanes,their preparation and use
IL95824A0 (en) Peptides associated with cd4 binding region of gp120 and their use
AU2146388A (en) Orthotic pads and methods
NZ220020A (en) 1-hydroxy-2-pyridones and pharmaceutical composition
JPS6454032A (en) Polydisilacyclobutasilazane and its preparation and use
GB2186291B (en) Alloy and product made therefrom
AU8316587A (en) Pharmaceutical compositions and their use
NZ226450A (en) Crystalline-1-carbacephalosporin and pharmaceutical compositions
AU7580187A (en) Androstane-type and cortical aminoesters
EP0435199A3 (en) Acrylic gel material and acrylic gel preparation
ZA882353B (en) Human tumour-associated antigen
EP0255801A3 (en) Anilinotriazines and their use
GB2197197B (en) Soluble and/or splitable tablets
ZW988A1 (en) Improved polymeric film-enveloped explosive catridges and their manufacture and use
NZ227594A (en) Human interleukin-1alpha and preparations thereof
PH24632A (en) Tin diiododeuteroporphyrin and therapeutic use thereof
IL92281A0 (en) Polyimidesiloxanes,their preparation and use
IL87779A0 (en) 4-azasaccharines,4-aza-dihydro-and-tetrahydro-saccharines and their preparation