NZ205320A - Benzodioxepine spiro derivatives and pharmaceutical compositions - Google Patents
Benzodioxepine spiro derivatives and pharmaceutical compositionsInfo
- Publication number
- NZ205320A NZ205320A NZ205320A NZ20532083A NZ205320A NZ 205320 A NZ205320 A NZ 205320A NZ 205320 A NZ205320 A NZ 205320A NZ 20532083 A NZ20532083 A NZ 20532083A NZ 205320 A NZ205320 A NZ 205320A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compound
- group
- formula
- piperidine
- straight chain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/410,155 US4405631A (en) | 1982-08-20 | 1982-08-20 | Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'pyrrolidine] compounds and their use as antihypertensive agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ205320A true NZ205320A (en) | 1987-05-29 |
Family
ID=23623465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ205320A NZ205320A (en) | 1982-08-20 | 1983-08-18 | Benzodioxepine spiro derivatives and pharmaceutical compositions |
Country Status (20)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4521537A (en) * | 1982-08-20 | 1985-06-04 | Hoechst-Roussel Pharmaceuticals Incorporated | Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine] compounds and their use as antihypertensive agents |
| US4472580A (en) * | 1982-08-20 | 1984-09-18 | Hoechst-Roussel Pharmaceuticals Incorporated | Spiro (2H-1,4-benzodioxepin-3 (5H)4-piperidine and -3-pyrrolidine) compounds and their use as anti-hypertensive agents |
| US4751223A (en) * | 1986-10-14 | 1988-06-14 | Hoechst-Roussel Pharmaceuticals, Inc. | Antiinflammatory and analgesic aminoalkyl tetracyclic benzodiazepines |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1312894A (fr) * | 1962-01-29 | 1962-12-21 | Geigy Ag J R | Nouveaux composés hétérocycliques à 2 atomes d'oxygène dans le cycle et leur préparation |
| CH469736A (de) * | 1966-06-28 | 1969-03-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Heterospiroalkanen |
| US3679666A (en) * | 1969-04-03 | 1972-07-25 | Hoffmann La Roche | 4-(4-hydroxypiperidino)-4'-fluorobutyrophenones |
-
1982
- 1982-08-20 US US06/410,155 patent/US4405631A/en not_active Expired - Fee Related
-
1983
- 1983-08-17 GR GR72231A patent/GR78667B/el unknown
- 1983-08-18 ES ES525013A patent/ES525013A0/es active Granted
- 1983-08-18 EP EP83108156A patent/EP0102034B1/en not_active Expired
- 1983-08-18 AT AT83108156T patent/ATE33656T1/de not_active IP Right Cessation
- 1983-08-18 DE DE8383108156T patent/DE3376327D1/de not_active Expired
- 1983-08-18 KR KR1019830003853A patent/KR840005729A/ko not_active Ceased
- 1983-08-18 PH PH29413A patent/PH18839A/en unknown
- 1983-08-18 FI FI832959A patent/FI832959A7/fi not_active Application Discontinuation
- 1983-08-18 NZ NZ205320A patent/NZ205320A/en unknown
- 1983-08-19 CA CA000434928A patent/CA1210764A/en not_active Expired
- 1983-08-19 JP JP58150473A patent/JPS5953489A/ja active Pending
- 1983-08-19 IL IL69525A patent/IL69525A0/xx unknown
- 1983-08-19 ZA ZA836127A patent/ZA836127B/xx unknown
- 1983-08-19 NO NO833001A patent/NO833001L/no unknown
- 1983-08-19 AU AU18169/83A patent/AU576473B2/en not_active Ceased
- 1983-08-19 HU HU832920A patent/HU191874B/hu unknown
- 1983-08-19 PT PT77223A patent/PT77223B/pt unknown
- 1983-08-19 DK DK381983A patent/DK381983A/da not_active Application Discontinuation
- 1983-08-20 MA MA20103A patent/MA19881A1/fr unknown
-
1985
- 1985-03-01 ES ES540841A patent/ES8602800A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| PT77223A (en) | 1983-09-01 |
| GR78667B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-09-27 |
| KR840005729A (ko) | 1984-11-16 |
| MA19881A1 (fr) | 1984-04-01 |
| JPS5953489A (ja) | 1984-03-28 |
| ZA836127B (en) | 1984-04-25 |
| ES8505685A1 (es) | 1985-06-01 |
| FI832959A7 (fi) | 1984-02-21 |
| DK381983A (da) | 1984-02-21 |
| ATE33656T1 (de) | 1988-05-15 |
| DE3376327D1 (en) | 1988-05-26 |
| EP0102034A1 (en) | 1984-03-07 |
| FI832959A0 (fi) | 1983-08-18 |
| DK381983D0 (da) | 1983-08-19 |
| ES540841A0 (es) | 1985-12-01 |
| AU576473B2 (en) | 1988-09-01 |
| NO833001L (no) | 1984-02-21 |
| HU191874B (en) | 1987-04-28 |
| ES8602800A1 (es) | 1985-12-01 |
| EP0102034B1 (en) | 1988-04-20 |
| IL69525A0 (en) | 1983-11-30 |
| US4405631A (en) | 1983-09-20 |
| PH18839A (en) | 1985-10-10 |
| AU1816983A (en) | 1984-02-23 |
| CA1210764A (en) | 1986-09-02 |
| ES525013A0 (es) | 1985-06-01 |
| PT77223B (en) | 1986-03-18 |
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