US5962490A
(en)
|
1987-09-25 |
1999-10-05 |
Texas Biotechnology Corporation |
Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
|
EP0668076B1
(en)
*
|
1992-08-26 |
2002-09-04 |
Sucampo AG |
Stabilization of a prostanoic acid compound
|
US6342610B2
(en)
|
1993-05-20 |
2002-01-29 |
Texas Biotechnology Corp. |
N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
|
SG100767A1
(en)
|
1997-04-28 |
2003-12-26 |
Texas Biotechnology Corp |
Sulfonamides for treatment of endothelin-mediated disorders
|
US5783705A
(en)
|
1997-04-28 |
1998-07-21 |
Texas Biotechnology Corporation |
Process of preparing alkali metal salys of hydrophobic sulfonamides
|
US6362009B1
(en)
|
1997-11-21 |
2002-03-26 |
Merck & Co., Inc. |
Solid phase synthesis of heterocycles
|
US7169410B1
(en)
|
1998-05-19 |
2007-01-30 |
Sdg, Inc. |
Targeted liposomal drug delivery system
|
WO2001036351A2
(en)
|
1999-11-19 |
2001-05-25 |
Corvas International, Inc. |
Plasminogen activator inhibitor antagonists related applications
|
US6638977B1
(en)
|
1999-11-19 |
2003-10-28 |
Corvas International, Inc. |
Plasminogen activator inhibitor antagonists
|
US7897140B2
(en)
|
1999-12-23 |
2011-03-01 |
Health Research, Inc. |
Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
|
CA2463724A1
(en)
*
|
2001-10-16 |
2003-04-24 |
Structural Bioinformatics Inc. |
Organosulfur inhibitors of tyrosine phosphatases
|
AUPR868201A0
(en)
*
|
2001-11-05 |
2001-11-29 |
Thorlock International Limited |
Q-factor switching method and apparatus for detecting nuclear quadrupole and nuclear magnetic resonance signals
|
US7482366B2
(en)
|
2001-12-21 |
2009-01-27 |
X-Ceptor Therapeutics, Inc. |
Modulators of LXR
|
EP1465869B1
(en)
|
2001-12-21 |
2013-05-15 |
Exelixis Patent Company LLC |
Modulators of lxr
|
WO2003060078A2
(en)
*
|
2001-12-21 |
2003-07-24 |
X-Ceptor Therapeutics, Inc. |
Heterocyclic modulators of nuclear receptors
|
ES2361403T3
(es)
|
2002-03-07 |
2011-06-16 |
X-Ceptor Therapeutics, Inc. |
Moduladores de quinazolinona de receptores nucleares.
|
US20040001801A1
(en)
*
|
2002-05-23 |
2004-01-01 |
Corvas International, Inc. |
Conjugates activated by cell surface proteases and therapeutic uses thereof
|
DE60328496D1
(en)
|
2002-06-27 |
2009-09-03 |
Health Research Inc |
Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie
|
AU2003249742A1
(en)
|
2002-07-02 |
2004-01-23 |
Health Research, Inc. |
Efficient synthesis of pyropheophorbide a and its derivatives
|
US7871607B2
(en)
*
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
SG2012041067A
(en)
|
2003-03-05 |
2014-08-28 |
Halozyme Inc |
Soluble hyaluronidase glycoprotein (shasegp), process for preparing the same, uses and pharmaceutical compositions comprising thereof
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
US7244739B2
(en)
*
|
2003-05-14 |
2007-07-17 |
Torreypines Therapeutics, Inc. |
Compounds and uses thereof in modulating amyloid beta
|
ES2332135T3
(es)
*
|
2003-06-03 |
2010-01-27 |
Novartis Ag |
Inhibidores p-38 basados en heterociclo de 5 miembros.
|
EP1911754B1
(en)
|
2003-08-13 |
2013-10-09 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
US7420000B2
(en)
|
2003-09-10 |
2008-09-02 |
University Of Southern California |
Amino phosphonate and amino bis-phosphonate derivatives
|
US20050203184A1
(en)
*
|
2003-09-10 |
2005-09-15 |
Petasis Nicos A. |
Benzo lipoxin analogues
|
CA2580584C
(en)
|
2003-09-19 |
2015-07-28 |
Galileo Pharmaceuticals, Inc. |
Use of alpha-tocotrienol for treatment of mitochondrial diseases
|
US20050148534A1
(en)
*
|
2003-09-22 |
2005-07-07 |
Castellino Angelo J. |
Small molecule compositions and methods for increasing drug efficiency using compositions thereof
|
WO2005090370A1
(en)
*
|
2004-02-05 |
2005-09-29 |
The Regents Of The University Of California |
Pharmacologically active agents containing esterified phosphonates and methods for use thereof
|
WO2005090282A1
(en)
|
2004-03-12 |
2005-09-29 |
Ligand Pharmaceuticals Incorporated |
Androgen receptor modulator compounds and methods
|
EP1755585A4
(en)
|
2004-05-20 |
2009-04-01 |
Scripps Research Inst |
Transthyretin STABILIZATION
|
EP1765332A2
(en)
*
|
2004-06-17 |
2007-03-28 |
Cengent Therapeutics, Inc. |
Trisubstituted nitrogen modulators of tyrosine phosphatases
|
US20060135483A1
(en)
*
|
2004-07-09 |
2006-06-22 |
Cheruvallath Zacharia S |
Oxygen/nitrogen heterocycle inhibitors of tyrosine phosphatases
|
EP1773348A4
(en)
|
2004-07-12 |
2009-05-20 |
Idun Pharmaceuticals Inc |
TETRA PEPTIDE ANALOGS
|
EP1841749A1
(en)
*
|
2004-09-02 |
2007-10-10 |
Metabasis Therapeutics, Inc. |
Derivatives of thiazole and thiadiazole inhibitors of tyrosine phosphatases
|
WO2006034003A2
(en)
|
2004-09-17 |
2006-03-30 |
Whitehead Institute For Biomedical Research |
Compounds, compositions and methods of inhibiting a-synuclein toxicity
|
EP1828192B1
(en)
|
2004-12-21 |
2014-12-03 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
EP1866319B1
(en)
|
2005-04-01 |
2011-11-23 |
The Regents of The University of California |
Phosphono-pent-2-en-1-yl nucleosides and analogs
|
EP1891067B1
(en)
*
|
2005-06-17 |
2016-01-13 |
Ligand Pharmaceuticals Incorporated |
Androgen receptor modulator compounds and methods
|
WO2007002109A2
(en)
*
|
2005-06-20 |
2007-01-04 |
The Regents Of The University Of California |
Multidentate pyrone-derived chelators for medicinal imaging and chelation
|
US20080058282A1
(en)
|
2005-08-30 |
2008-03-06 |
Fallon Joan M |
Use of lactulose in the treatment of autism
|
WO2008051197A2
(en)
*
|
2005-09-20 |
2008-05-02 |
Mayo Foundation For Medical Education And Research |
Small-molecule botulinum toxin inhibitors
|
US8119655B2
(en)
|
2005-10-07 |
2012-02-21 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
US8138361B2
(en)
*
|
2005-12-28 |
2012-03-20 |
The Trustees Of The University Of Pennsylvania |
C-10 carbamates of taxanes
|
KR101465269B1
(ko)
|
2006-01-24 |
2014-11-26 |
가부시키가이샤 아루떼꾸 우에노 |
바이-사이클릭 화합물을 함유하는 약학적 조성물 및 바이-사이클릭 화합물의 안정화 방법
|
JP2009531443A
(ja)
*
|
2006-03-29 |
2009-09-03 |
フォールドアールエックス ファーマシューティカルズ インコーポレーティッド |
α−シヌクレイン毒性の抑制
|
EP2292663B1
(en)
|
2006-08-28 |
2013-10-02 |
Kyowa Hakko Kirin Co., Ltd. |
Antagonistic human light-specific human monoclonal antibodies
|
EP2223925A1
(en)
|
2006-10-09 |
2010-09-01 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
AU2007313961A1
(en)
|
2006-10-09 |
2008-05-08 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
JP2010508307A
(ja)
|
2006-10-31 |
2010-03-18 |
武田薬品工業株式会社 |
Mapk/erkキナーゼ阻害剤
|
JP5372939B2
(ja)
|
2007-09-25 |
2013-12-18 |
武田薬品工業株式会社 |
ポロ様キナーゼ阻害剤
|
US20090264421A1
(en)
*
|
2007-10-05 |
2009-10-22 |
Bible Keith C |
Methods and Compositions for Treating Cancer
|
CA2706465A1
(en)
*
|
2007-11-21 |
2009-05-28 |
Pharmaxis Ltd. |
Haloallylamine inhibitors of ssao/vap-1 and uses therefor
|
WO2009082437A2
(en)
|
2007-12-21 |
2009-07-02 |
Ligand Pharmaceuticals Incorporated |
Selective androgen receptor modulators (sarms) and uses thereof
|
US8658163B2
(en)
|
2008-03-13 |
2014-02-25 |
Curemark Llc |
Compositions and use thereof for treating symptoms of preeclampsia
|
US8084025B2
(en)
|
2008-04-18 |
2011-12-27 |
Curemark Llc |
Method for the treatment of the symptoms of drug and alcohol addiction
|
US20110178070A1
(en)
|
2008-06-24 |
2011-07-21 |
Takeda Pharmaceutical Company Limited |
PI3K/mTOR INHIBITORS
|
US11016104B2
(en)
|
2008-07-01 |
2021-05-25 |
Curemark, Llc |
Methods and compositions for the treatment of symptoms of neurological and mental health disorders
|
ES2727746T3
(es)
|
2009-01-06 |
2019-10-18 |
Galenagen Llc |
Composiciones orales para el tratamiento o la prevención de infecciones por E. Coli
|
WO2010080830A1
(en)
|
2009-01-06 |
2010-07-15 |
Curemark Llc |
Compositions and methods for the treatment or prevention of staphylococcus aureus infections and for the eradication or reduction of staphylococcus aureus on surfaces
|
EP2415767B1
(en)
|
2009-03-27 |
2014-09-03 |
Takeda Pharmaceutical Company Limited |
Poly (ADP-ribose) Polymerase (PARP) Inhibitors
|
US9056050B2
(en)
|
2009-04-13 |
2015-06-16 |
Curemark Llc |
Enzyme delivery systems and methods of preparation and use
|
WO2011014681A1
(en)
|
2009-07-30 |
2011-02-03 |
Takeda Pharmaceutical Company Limited |
Poly (ADP-Ribose) Polymerase (PARP) INHIBITORS
|
US8404728B2
(en)
|
2009-07-30 |
2013-03-26 |
Mayo Foundation For Medical Education And Research |
Small-molecule botulinum toxin inhibitors
|
WO2011041293A1
(en)
|
2009-09-30 |
2011-04-07 |
Takeda Pharmaceutical Company Limited |
Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
|
WO2011057214A2
(en)
|
2009-11-09 |
2011-05-12 |
Neurogenetic Pharmaceuticals, Inc. |
Gamma-secretase modulatory compounds, methods for identifying same, and uses therefor
|
WO2011069002A1
(en)
|
2009-12-02 |
2011-06-09 |
Alquest Therapeutics, Inc. |
Organoselenium compounds and uses thereof
|
EP2515654A4
(en)
*
|
2009-12-23 |
2013-04-24 |
Map Pharmaceuticals Inc |
NEW ERGOLINANALOGA
|
HRP20140114T1
(hr)
|
2010-02-03 |
2014-03-14 |
Takeda Pharmaceutical Company Limited |
Inhibitori kinaze 1 koji reguliraju signal apoptoze
|
US9403815B2
(en)
|
2010-06-24 |
2016-08-02 |
The Regents Of The University Of California |
Compounds and uses thereof in modulating levels of various amyloid beta peptide alloforms
|
MX362974B
(es)
|
2011-04-21 |
2019-02-28 |
Curemark Llc |
Compuestos para el tratamiento de alteraciones neuropsiquiatricas.
|
CN103827113A
(zh)
|
2011-06-23 |
2014-05-28 |
Map药物公司 |
新型氟麦角碱类似物
|
WO2013037482A1
(en)
|
2011-09-15 |
2013-03-21 |
Phenex Pharmaceuticals Ag |
Farnesoid x receptor agonists for cancer treatment and prevention
|
CA2859173A1
(en)
|
2011-12-19 |
2013-06-27 |
Map Pharmaceuticals, Inc. |
Novel iso-ergoline derivatives
|
CA2859175A1
(en)
|
2011-12-21 |
2013-06-27 |
Map Pharmaceuticals, Inc. |
Novel neuromodulatory compounds
|
IN2012DE00661A
(GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
|
2012-03-07 |
2015-08-21 |
Univ Delhi |
|
RS57086B1
(sr)
|
2012-05-02 |
2018-06-29 |
Boehringer Ingelheim Int |
Supstituisani 3-haloalilamin inhibitori ssao i njihova primena
|
US10350278B2
(en)
|
2012-05-30 |
2019-07-16 |
Curemark, Llc |
Methods of treating Celiac disease
|
EP2861562B1
(en)
|
2012-06-14 |
2018-05-09 |
Mayo Foundation For Medical Education And Research |
Pyrazole derivatives as inhibitors of stat3
|
US9012640B2
(en)
|
2012-06-22 |
2015-04-21 |
Map Pharmaceuticals, Inc. |
Cabergoline derivatives
|
US8551535B1
(en)
|
2012-08-06 |
2013-10-08 |
Sarah McCann |
Homeopathic remedies and methods for enhancing weight loss
|
US9074186B2
(en)
|
2012-08-15 |
2015-07-07 |
Boston Medical Center Corporation |
Production of red blood cells and platelets from stem cells
|
AU2013361340A1
(en)
|
2012-12-21 |
2015-07-09 |
Map Pharmaceuticals, Inc. |
Novel methysergide derivatives
|
US9169214B2
(en)
|
2012-12-21 |
2015-10-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
|
WO2014130908A1
(en)
|
2013-02-22 |
2014-08-28 |
University Of Southern California |
Methods for treatment of ophthalmic diseases and disorders
|
WO2014165263A1
(en)
|
2013-03-12 |
2014-10-09 |
The Regents Of The University Of California, A California Corporation |
Gamma-secretase modulators
|
US9732074B2
(en)
|
2013-03-15 |
2017-08-15 |
University Of Southern California |
Methods, compounds, and compositions for the treatment of angiotensin-related diseases
|
US10100123B2
(en)
|
2013-06-06 |
2018-10-16 |
Pierre Fabre Medicament |
Anti-C10orf54 antibodies and uses thereof
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
JP6543342B2
(ja)
|
2014-08-14 |
2019-07-10 |
アルハマドシャー,マモウン,エム. |
血清半減期を延長するための、調節可能リンカーを介した薬学的活性剤とトランスサイレチンリガンドのコンジュゲーション
|
MX381224B
(es)
|
2014-10-31 |
2025-03-12 |
Massachusetts Gen Hospital |
Potentes moduladores de gamma-secretasa.
|
ES2834739T3
(es)
|
2014-12-11 |
2021-06-18 |
Pf Medicament |
Anticuerpos anti-C10orf54 y utilizaciones de los mismos
|
JP2018502889A
(ja)
|
2015-01-20 |
2018-02-01 |
エックスオーシー ファーマシューティカルズ インコーポレイテッドXoc Pharmaceuticals, Inc |
イソエルゴリン化合物およびその使用
|
CA2974117A1
(en)
|
2015-01-20 |
2016-07-28 |
Xoc Pharmaceuticals, Inc. |
Ergoline compounds and uses thereof
|
CN108064169B
(zh)
|
2015-03-03 |
2022-02-11 |
科马布有限公司 |
抗体、用途和方法
|
US20180156807A1
(en)
|
2015-04-29 |
2018-06-07 |
New York University |
Method for treating high-grade gliomas
|
CN108883103A
(zh)
|
2015-12-02 |
2018-11-23 |
阿斯特来亚治疗有限责任公司 |
哌啶基痛敏肽受体化合物
|
US10112924B2
(en)
|
2015-12-02 |
2018-10-30 |
Astraea Therapeutics, Inc. |
Piperdinyl nociceptin receptor compounds
|
US10717734B2
(en)
|
2016-02-12 |
2020-07-21 |
Pharmaxis Ltd. |
Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof
|
US10960013B2
(en)
|
2016-03-04 |
2021-03-30 |
East Carolina University |
J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders
|
EP3426301A4
(en)
|
2016-03-08 |
2019-11-06 |
Los Gatos Pharmaceuticals, Inc. |
VERBUNDNANOPARTICLES AND USES THEREOF
|
JP2019513151A
(ja)
|
2016-03-08 |
2019-05-23 |
ロス ガトス ファーマスーティカルズ, インク.Los Gatos Pharmaceuticals, Inc. |
カンプトテシン誘導体及びその使用
|
US10047077B2
(en)
|
2016-04-13 |
2018-08-14 |
Skyline Antiinfectives, Inc. |
Deuterated O-sulfated beta-lactam hydroxamic acids and deuterated N-sulfated beta-lactams
|
US20190160052A1
(en)
|
2016-05-13 |
2019-05-30 |
Institut Pasteur |
Inhibition of beta-2 nicotinic acetylcholine receptors to treat alzheimer's disease pathology
|
WO2018035281A1
(en)
|
2016-08-17 |
2018-02-22 |
North Carolina State University |
Northern-southern route to synthesis of bacteriochlorins
|
EP3534947A1
(en)
|
2016-11-03 |
2019-09-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
US10106521B2
(en)
|
2016-11-09 |
2018-10-23 |
Phloronol, Inc. |
Eckol derivatives, methods of synthesis and uses thereof
|
US10836774B2
(en)
|
2016-11-30 |
2020-11-17 |
North Carolina State University |
Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds
|
EA201991921A1
(ru)
|
2017-02-17 |
2020-02-06 |
Эйдос Терапьютикс, Инк. |
Способы получения ag-10, его промежуточных соединений и их солей
|
AU2018250823A1
(en)
|
2017-04-10 |
2019-10-17 |
Curemark, Llc |
Compositions for treating addiction
|
US10085999B1
(en)
|
2017-05-10 |
2018-10-02 |
Arixa Pharmaceuticals, Inc. |
Beta-lactamase inhibitors and uses thereof
|
BR112019025420A2
(pt)
|
2017-06-01 |
2020-06-16 |
Xoc Pharmaceuticals, Inc. |
Compostos policíclicos e usos destes
|
EP4265257A1
(en)
|
2017-09-01 |
2023-10-25 |
East Carolina University |
Combination of a j-series prostaglandin-ethanolamide and a checkpoint inhibitor for use in treating cancer
|
WO2019099353A1
(en)
|
2017-11-15 |
2019-05-23 |
California State University Northridge |
Compositions and methods for the treatment and prevention of cancer
|
SG11202009073WA
(en)
|
2018-03-23 |
2020-10-29 |
Eidos Therapeutics Inc |
Methods of treating ttr amyloidosis using ag10
|
JP2021531007A
(ja)
|
2018-07-20 |
2021-11-18 |
ピエール、ファーブル、メディカマン |
Vistaに対する受容体
|
AU2019315330B2
(en)
|
2018-08-03 |
2024-10-17 |
Syntara Limited |
Haloallylamine sulfone derivative inhibitors of lysyl oxidases and uses thereof
|
WO2020037189A1
(en)
|
2018-08-17 |
2020-02-20 |
Eidos Therapeutics, Inc. |
Formulations of ag10
|
WO2020128033A1
(en)
|
2018-12-20 |
2020-06-25 |
Institut Pasteur |
Cellular metabolism of hiv-1 reservoir seeding in cd4+ t cells
|
US11447468B2
(en)
|
2019-02-06 |
2022-09-20 |
Dice Alpha, Inc. |
IL-17 ligands and uses thereof
|
US12319651B2
(en)
|
2019-04-19 |
2025-06-03 |
Ligand Pharmaceuticals Incorporated |
Crystalline forms and methods of producing crystalline forms of a compound
|
US20220249707A1
(en)
|
2019-05-20 |
2022-08-11 |
Nirvana Sciences Inc. |
Narrow emission dyes, compositions comprising same, and methods for making and using same
|
EP4031534A1
(en)
|
2019-09-16 |
2022-07-27 |
Dice Alpha, Inc. |
Il-17a modulators and uses thereof
|
JP2023532312A
(ja)
|
2020-06-30 |
2023-07-27 |
プロセッタ バイオサイエンシズ, インク. |
イソキノリン誘導体、合成の方法及びそれらの使用
|
US11541009B2
(en)
|
2020-09-10 |
2023-01-03 |
Curemark, Llc |
Methods of prophylaxis of coronavirus infection and treatment of coronaviruses
|
KR20230169979A
(ko)
|
2021-03-10 |
2023-12-18 |
다이스 몰레큘스 에스브이, 인크. |
알파 v 베타 6 및 알파 v 베타 1 인테그린 억제제 및 그의 용도
|
AU2022368836A1
(en)
|
2021-10-22 |
2024-05-02 |
Prosetta Biosciences, Inc. |
Novel host-targeted pan-respiratory antiviral small molecule therapeutics
|
US11932665B2
(en)
|
2022-01-03 |
2024-03-19 |
Lilac Therapeutics, Inc. |
Cyclic thiol prodrugs
|
US11981694B2
(en)
|
2022-01-03 |
2024-05-14 |
Lilac Therapeutics, Inc. |
Acyclic thiol prodrugs
|
CN118922189A
(zh)
|
2022-03-02 |
2024-11-08 |
线粒体能量有限公司 |
衍生自烟酸和核糖的新型前药
|
GB2619907A
(en)
|
2022-04-01 |
2023-12-27 |
Kanna Health Ltd |
Novel crystalline salt forms of mesembrine
|
GB2636969A
(en)
|
2023-11-24 |
2025-07-09 |
Ontrack Therapeutics Ltd |
Novel crystalline salt forms
|