NO995127D0 - Stabiliserte tibolonblandinger - Google Patents
Stabiliserte tibolonblandingerInfo
- Publication number
- NO995127D0 NO995127D0 NO995127A NO995127A NO995127D0 NO 995127 D0 NO995127 D0 NO 995127D0 NO 995127 A NO995127 A NO 995127A NO 995127 A NO995127 A NO 995127A NO 995127 D0 NO995127 D0 NO 995127D0
- Authority
- NO
- Norway
- Prior art keywords
- mixtures
- tibolone
- dosage unit
- stabilized
- stabilized tibolone
- Prior art date
Links
- WZDGZWOAQTVYBX-XOINTXKNSA-N tibolone Chemical compound C([C@@H]12)C[C@]3(C)[C@@](C#C)(O)CC[C@H]3[C@@H]1[C@H](C)CC1=C2CCC(=O)C1 WZDGZWOAQTVYBX-XOINTXKNSA-N 0.000 title abstract 2
- 229960001023 tibolone Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 239000003937 drug carrier Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97201180 | 1997-04-22 | ||
| PCT/EP1998/002361 WO1998047517A1 (en) | 1997-04-22 | 1998-04-20 | Stabilized tibolone compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO995127D0 true NO995127D0 (no) | 1999-10-21 |
| NO995127L NO995127L (no) | 1999-10-21 |
Family
ID=8228228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO995127A NO995127L (no) | 1997-04-22 | 1999-10-21 | Stabiliserte tibolonblandinger |
Country Status (25)
| Country | Link |
|---|---|
| US (6) | US6399594B2 (enExample) |
| EP (1) | EP0975348B1 (enExample) |
| JP (1) | JPH10316573A (enExample) |
| KR (1) | KR100580855B1 (enExample) |
| CN (2) | CN1146424C (enExample) |
| AR (1) | AR012480A1 (enExample) |
| AT (1) | ATE281836T1 (enExample) |
| AU (1) | AU742037B2 (enExample) |
| BR (1) | BR9809268A (enExample) |
| CA (1) | CA2288070A1 (enExample) |
| DE (1) | DE69827484T2 (enExample) |
| DK (1) | DK0975348T3 (enExample) |
| ES (1) | ES2232949T3 (enExample) |
| HU (1) | HUP0001780A3 (enExample) |
| ID (1) | ID22763A (enExample) |
| IL (1) | IL123984A (enExample) |
| NO (1) | NO995127L (enExample) |
| NZ (1) | NZ338028A (enExample) |
| PL (1) | PL190227B1 (enExample) |
| PT (1) | PT975348E (enExample) |
| RU (1) | RU2207133C2 (enExample) |
| TR (1) | TR199902530T2 (enExample) |
| TW (1) | TW570798B (enExample) |
| WO (1) | WO1998047517A1 (enExample) |
| ZA (1) | ZA983169B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ510501A (en) * | 1998-10-16 | 2003-10-31 | Akzo Nobel Nv | High purity composition comprising (7alpha,17beta)- 17- hydroxy- 7-methyl- 19-nor-17-pregn- 5(10)-en-20-yn-3-one |
| AU754712B2 (en) * | 1999-02-26 | 2002-11-21 | Shionogi & Co., Ltd. | Chewable soft capsules having improved administration properties and process for producing the same |
| US20040229854A1 (en) * | 2000-11-28 | 2004-11-18 | Pieter Haan De | Immediate release dosage form for HRT |
| US20070098784A1 (en) * | 2001-09-28 | 2007-05-03 | Nutraceutix, Inc. | Delivery system for biological component |
| PT1429802E (pt) * | 2001-09-28 | 2013-01-24 | Tntgamble Inc | Sistema de entrega para componente biológico |
| GB0125061D0 (en) * | 2001-10-18 | 2001-12-12 | Norton Healthcare Ltd | Pharmaceutical composition |
| TW200418525A (en) * | 2002-11-20 | 2004-10-01 | Akzo Nobel Nv | Coated pharmaceutical tablets containing Tibolone |
| CN1324041C (zh) * | 2003-04-01 | 2007-07-04 | 上海迪赛诺医药科技开发有限公司 | 替勃龙晶型i的制备方法 |
| MXPA05011626A (es) * | 2003-04-29 | 2006-01-23 | Akzo Nobel Nv | Procedimiento de soldificacion con antisolvente. |
| AU2004203420B8 (en) * | 2003-05-23 | 2008-02-21 | N.V. Organon | Immediate-release pharmaceutical dosage form comprising polymorphous tibolone |
| EP1742615A2 (en) * | 2004-05-05 | 2007-01-17 | Akzo Nobel N.V. | Antisolvent emulsion solidification process |
| WO2005117899A1 (en) * | 2004-06-02 | 2005-12-15 | Cipla Limited | Pharmaceutical composition comprising tibolone and process for procuding the same |
| WO2005120517A1 (en) * | 2004-06-07 | 2005-12-22 | Strides Arcolab Limited | Stable liquid suspension formulation comprising synthetic steroids and process for producing the same |
| CZ300465B6 (cs) * | 2007-07-25 | 2009-05-27 | Zentiva, A. S. | Zpusob výroby komprimované farmaceutické formulace s obsahem tibolonu |
| CN102085193B (zh) * | 2009-12-08 | 2013-11-06 | 北京以岭生物工程技术有限公司 | 一种替勃龙口腔崩解片及其制备方法 |
| CN104345098B (zh) * | 2013-08-05 | 2016-04-13 | 华润紫竹药业有限公司 | 一种测定替勃龙片剂中抗氧剂含量的方法 |
| AU2017260799B2 (en) | 2016-05-04 | 2022-11-24 | Novalon S.A. | Use of sugar-alcohols in tibolone compositions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4701450A (en) * | 1984-03-21 | 1987-10-20 | Akzo N.V. | Steroids for use as immunomodulators |
| CH676470A5 (enExample) * | 1988-02-03 | 1991-01-31 | Nestle Sa | |
| IE63051B1 (en) | 1989-03-18 | 1995-03-22 | Akzo Nv | Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn- 3-one |
| DE69418744T2 (de) | 1993-03-05 | 1999-11-11 | Akzo Nobel N.V., Arnheim/Arnhem | Verwendung von Pregnanderivaten zur Behandlung von Tumoren |
| ES2185666T3 (es) | 1993-09-03 | 2003-05-01 | Smithkline Beecham Corp | Formulacion estabilizada para comprimidos. |
| CA2159419C (en) * | 1994-10-17 | 2006-07-04 | Pieter De Haan | Solid pharmaceutical composition comprising an excipient capable of binding water |
-
1998
- 1998-04-07 IL IL12398498A patent/IL123984A/en active IP Right Grant
- 1998-04-15 ZA ZA983169A patent/ZA983169B/xx unknown
- 1998-04-20 CA CA002288070A patent/CA2288070A1/en not_active Abandoned
- 1998-04-20 CN CNB988044579A patent/CN1146424C/zh not_active Expired - Fee Related
- 1998-04-20 WO PCT/EP1998/002361 patent/WO1998047517A1/en not_active Ceased
- 1998-04-20 PL PL98336658A patent/PL190227B1/pl not_active IP Right Cessation
- 1998-04-20 PT PT98928214T patent/PT975348E/pt unknown
- 1998-04-20 DK DK98928214T patent/DK0975348T3/da active
- 1998-04-20 AU AU80146/98A patent/AU742037B2/en not_active Ceased
- 1998-04-20 KR KR1019997009726A patent/KR100580855B1/ko not_active Expired - Fee Related
- 1998-04-20 AT AT98928214T patent/ATE281836T1/de not_active IP Right Cessation
- 1998-04-20 RU RU99121407/14A patent/RU2207133C2/ru not_active IP Right Cessation
- 1998-04-20 HU HU0001780A patent/HUP0001780A3/hu unknown
- 1998-04-20 US US09/403,139 patent/US6399594B2/en not_active Expired - Fee Related
- 1998-04-20 TR TR1999/02530T patent/TR199902530T2/xx unknown
- 1998-04-20 DE DE69827484T patent/DE69827484T2/de not_active Expired - Fee Related
- 1998-04-20 NZ NZ338028A patent/NZ338028A/en unknown
- 1998-04-20 BR BR9809268-5A patent/BR9809268A/pt not_active Application Discontinuation
- 1998-04-20 ID IDW991204A patent/ID22763A/id unknown
- 1998-04-20 ES ES98928214T patent/ES2232949T3/es not_active Expired - Lifetime
- 1998-04-20 EP EP98928214A patent/EP0975348B1/en not_active Expired - Lifetime
- 1998-04-20 CN CNA2003101026335A patent/CN1494908A/zh active Pending
- 1998-04-21 AR ARP980101819A patent/AR012480A1/es not_active Application Discontinuation
- 1998-04-22 JP JP10112312A patent/JPH10316573A/ja active Pending
- 1998-05-11 TW TW087107211A patent/TW570798B/zh not_active IP Right Cessation
-
1999
- 1999-10-21 NO NO995127A patent/NO995127L/no unknown
-
2002
- 2002-04-08 US US10/117,899 patent/US6514958B1/en not_active Expired - Fee Related
- 2002-11-25 US US10/303,494 patent/US20030119801A1/en not_active Abandoned
-
2004
- 2004-01-08 US US10/754,733 patent/US20040142031A1/en not_active Abandoned
- 2004-01-08 US US10/754,685 patent/US20040142030A1/en not_active Abandoned
- 2004-01-08 US US10/754,732 patent/US20040142028A1/en not_active Abandoned
Also Published As
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