NO992724L - Pharmaceutical mixtures containing N-sulfonyl-indoline derivatives - Google Patents
Pharmaceutical mixtures containing N-sulfonyl-indoline derivativesInfo
- Publication number
- NO992724L NO992724L NO992724A NO992724A NO992724L NO 992724 L NO992724 L NO 992724L NO 992724 A NO992724 A NO 992724A NO 992724 A NO992724 A NO 992724A NO 992724 L NO992724 L NO 992724L
- Authority
- NO
- Norway
- Prior art keywords
- amphiphilic
- sulfonyl
- mixtures containing
- surfactant
- indoline derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Foreliggende oppfinnelse angår et vannfritt solubiliserings/stabiliserings- system som er emulgerbart eller mikroemulgerbart i vann, for solubiliseringen av hydrofobe derivater av N-sulfonylindolin med formel: OCH kjennetegnet ved at det omfatter en eller flere bestanddeler valgt fra amfifile for- bindelser, ikke-ioniske, hydrofile, overflateaktive midler og ikke-ioniske, hydrofile forbindelser utstyrt med både amfifile og overflateaktive egenskaper, idet det skal forstås at det nevnte system omfatter enten minst en blanding av en amfifil forbin- delse og av et ikke-ionisk, hydrofilt, overflateaktivt middel eller minst en ikke- ionisk, hydrofil forbindelse utstyrt med både overflateaktive og amfifile egenskaper.The present invention relates to an anhydrous solubilization / stabilization system which is emulsifiable or microemulsifiable in water, for the solubilization of hydrophobic derivatives of N-sulfonylindoline of formula: AND characterized by comprising one or more constituents selected from amphiphilic compounds, nonionic hydrophilic surfactants and nonionic hydrophilic compounds having both amphiphilic and surfactant properties, it being understood that said system comprises either at least one mixture of an amphiphilic compound and of a nonionic hydrophilic surfactant. or at least a nonionic, hydrophilic compound equipped with both surfactant and amphiphilic properties.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9614957A FR2756736B1 (en) | 1996-12-05 | 1996-12-05 | PHARMACEUTICAL COMPOSITIONS CONTAINING N-SULFONYL INDOLINE DERIVATIVES |
| PCT/FR1997/002210 WO1998024430A1 (en) | 1996-12-05 | 1997-12-04 | Pharmaceutical compositions containing n-sulphonyl indolin derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO992724L true NO992724L (en) | 1999-06-04 |
| NO992724D0 NO992724D0 (en) | 1999-06-04 |
Family
ID=9498376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO992724A NO992724D0 (en) | 1996-12-05 | 1999-06-04 | Pharmaceutical mixtures containing N-sulfonyl-indoline derivatives |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0941090A1 (en) |
| JP (1) | JP2000507618A (en) |
| KR (1) | KR20000069308A (en) |
| CN (1) | CN1239887A (en) |
| AR (1) | AR009651A1 (en) |
| AU (1) | AU716575B2 (en) |
| BR (1) | BR9712406A (en) |
| CA (1) | CA2273990A1 (en) |
| CO (1) | CO4910129A1 (en) |
| DZ (1) | DZ2362A1 (en) |
| EE (1) | EE9900206A (en) |
| FR (1) | FR2756736B1 (en) |
| HU (1) | HUP0001386A3 (en) |
| ID (1) | ID23373A (en) |
| IL (1) | IL129936A0 (en) |
| IS (1) | IS5062A (en) |
| MY (1) | MY132819A (en) |
| NO (1) | NO992724D0 (en) |
| NZ (1) | NZ335750A (en) |
| RU (1) | RU2174394C2 (en) |
| SK (1) | SK75599A3 (en) |
| TR (1) | TR199901702T2 (en) |
| WO (1) | WO1998024430A1 (en) |
| YU (1) | YU23099A (en) |
| ZA (1) | ZA9710919B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2786486B3 (en) * | 1998-11-16 | 2000-12-08 | Sanofi Sa | PROCESS FOR THE PREPARATION OF (2S) -1 - [(2R, 3S) -5-CHLORO-3- (2- CHLOROPHENYL) -1- (3,4-DIMETHOXY BENZENESULFONYL) -3-HYDROXY- 2,3-DIHYDRO- 1H-INDOLE-2-CARBONYL] PYRROLIDINE-2-CARBOXAMIDE, ITS SOLVATES AND / OR HYDRATES |
| DE19913692A1 (en) * | 1999-03-25 | 2000-09-28 | Basf Ag | Mechanically stable pharmaceutical dosage forms containing liquid or semi-solid surface-active substances |
| US6437006B1 (en) | 1999-09-27 | 2002-08-20 | American Cyanamid Company | Pharmaceutical carrier formulation |
| JP5767429B2 (en) | 1999-11-12 | 2015-08-19 | アッヴィ・インコーポレイテッド | Crystallization inhibitors in solid dispersants |
| FR2805992A1 (en) * | 2000-03-08 | 2001-09-14 | Sanofi Synthelabo | Oral administration of N-sulfonyl-indoline derivative to treat central nervous system, cardiovascular or gastric disorders, using polyethylene glycol, polysorbate and poloxamer as solubilizers for high bioavailability |
| DE10026698A1 (en) | 2000-05-30 | 2001-12-06 | Basf Ag | Self-emulsifying active ingredient formulation and use of this formulation |
| ITMI20011338A1 (en) | 2001-06-26 | 2002-12-26 | Farmatron Ltd | ORAL PHARMACEUTICAL COMPOSITIONS WITH IMMEDIATE RELEASE OF THE ACTIVE INGREDIENT |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| UA119324C2 (en) * | 2013-04-02 | 2019-06-10 | Теміс Медікер Лімітед | Compositions of pharmaceutical actives containing diethylene glycol monoethyl ether or other alkyl derivatives |
| KR102139339B1 (en) * | 2013-06-24 | 2020-07-29 | 주식회사 엘지생활건강 | Cosmetic composition which has improved solubility comprising indole compound |
| KR102139338B1 (en) * | 2013-06-24 | 2020-07-29 | 주식회사 엘지생활건강 | Cosmetic composition which has improved solubility comprising indole compound |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3237814A1 (en) * | 1982-10-12 | 1984-04-12 | Warner-Lambert Co., 07950 Morris Plains, N.J. | WATER-FREE EMULSIONS AND USE THEREOF |
| FR2679903B1 (en) * | 1991-08-02 | 1993-12-03 | Elf Sanofi | DERIVATIVES OF N-SULFONYL INDOLINE CARRYING AN AMIDIC FUNCTION, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME. |
-
1996
- 1996-12-05 FR FR9614957A patent/FR2756736B1/en not_active Expired - Fee Related
-
1997
- 1997-12-03 DZ DZ970212A patent/DZ2362A1/en active
- 1997-12-04 KR KR1019997004983A patent/KR20000069308A/en not_active Application Discontinuation
- 1997-12-04 AR ARP970105696A patent/AR009651A1/en unknown
- 1997-12-04 WO PCT/FR1997/002210 patent/WO1998024430A1/en not_active Application Discontinuation
- 1997-12-04 ID IDW990445D patent/ID23373A/en unknown
- 1997-12-04 JP JP10525294A patent/JP2000507618A/en active Pending
- 1997-12-04 CO CO97071118A patent/CO4910129A1/en unknown
- 1997-12-04 AU AU53262/98A patent/AU716575B2/en not_active Ceased
- 1997-12-04 SK SK755-99A patent/SK75599A3/en unknown
- 1997-12-04 NZ NZ335750A patent/NZ335750A/en unknown
- 1997-12-04 IL IL12993697A patent/IL129936A0/en unknown
- 1997-12-04 TR TR1999/01702T patent/TR199901702T2/en unknown
- 1997-12-04 ZA ZA9710919A patent/ZA9710919B/en unknown
- 1997-12-04 BR BR9712406-0A patent/BR9712406A/en unknown
- 1997-12-04 RU RU99114019/14A patent/RU2174394C2/en active
- 1997-12-04 CA CA002273990A patent/CA2273990A1/en not_active Abandoned
- 1997-12-04 EE EEP199900206A patent/EE9900206A/en unknown
- 1997-12-04 MY MYPI97005848A patent/MY132819A/en unknown
- 1997-12-04 HU HU0001386A patent/HUP0001386A3/en unknown
- 1997-12-04 EP EP97950228A patent/EP0941090A1/en not_active Withdrawn
- 1997-12-04 CN CN97180304A patent/CN1239887A/en active Pending
-
1999
- 1999-05-26 YU YU23099A patent/YU23099A/en unknown
- 1999-06-01 IS IS5062A patent/IS5062A/en unknown
- 1999-06-04 NO NO992724A patent/NO992724D0/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BR9712406A (en) | 1999-08-31 |
| WO1998024430A1 (en) | 1998-06-11 |
| EE9900206A (en) | 1999-12-15 |
| FR2756736B1 (en) | 1999-03-05 |
| YU23099A (en) | 1999-11-22 |
| SK75599A3 (en) | 2000-08-14 |
| TR199901702T2 (en) | 1999-09-21 |
| RU2174394C2 (en) | 2001-10-10 |
| NO992724D0 (en) | 1999-06-04 |
| HUP0001386A2 (en) | 2001-04-28 |
| CO4910129A1 (en) | 2000-04-24 |
| EP0941090A1 (en) | 1999-09-15 |
| AU5326298A (en) | 1998-06-29 |
| ZA9710919B (en) | 1999-06-04 |
| ID23373A (en) | 2000-04-20 |
| FR2756736A1 (en) | 1998-06-12 |
| DZ2362A1 (en) | 2002-12-28 |
| AR009651A1 (en) | 2000-04-26 |
| CA2273990A1 (en) | 1998-06-11 |
| CN1239887A (en) | 1999-12-29 |
| IL129936A0 (en) | 2000-02-29 |
| JP2000507618A (en) | 2000-06-20 |
| HUP0001386A3 (en) | 2002-03-28 |
| MY132819A (en) | 2007-10-31 |
| IS5062A (en) | 1999-06-01 |
| AU716575B2 (en) | 2000-03-02 |
| NZ335750A (en) | 2001-06-29 |
| KR20000069308A (en) | 2000-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |