FR2756736B1 - PHARMACEUTICAL COMPOSITIONS CONTAINING N-SULFONYL INDOLINE DERIVATIVES - Google Patents

PHARMACEUTICAL COMPOSITIONS CONTAINING N-SULFONYL INDOLINE DERIVATIVES

Info

Publication number
FR2756736B1
FR2756736B1 FR9614957A FR9614957A FR2756736B1 FR 2756736 B1 FR2756736 B1 FR 2756736B1 FR 9614957 A FR9614957 A FR 9614957A FR 9614957 A FR9614957 A FR 9614957A FR 2756736 B1 FR2756736 B1 FR 2756736B1
Authority
FR
France
Prior art keywords
pharmaceutical compositions
compositions containing
indoline derivatives
sulfonyl
sulfonyl indoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9614957A
Other languages
French (fr)
Other versions
FR2756736A1 (en
Inventor
Jean Claude Gautier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR9614957A priority Critical patent/FR2756736B1/en
Priority to DZ970212A priority patent/DZ2362A1/en
Priority to IDW990445D priority patent/ID23373A/en
Priority to CN97180304A priority patent/CN1239887A/en
Priority to ZA9710919A priority patent/ZA9710919B/en
Priority to RU99114019/14A priority patent/RU2174394C2/en
Priority to PCT/FR1997/002210 priority patent/WO1998024430A1/en
Priority to TR1999/01702T priority patent/TR199901702T2/en
Priority to CO97071118A priority patent/CO4910129A1/en
Priority to EEP199900206A priority patent/EE9900206A/en
Priority to SK755-99A priority patent/SK75599A3/en
Priority to KR1019997004983A priority patent/KR20000069308A/en
Priority to BR9712406-0A priority patent/BR9712406A/en
Priority to CA002273990A priority patent/CA2273990A1/en
Priority to ARP970105696A priority patent/AR009651A1/en
Priority to IL12993697A priority patent/IL129936A0/en
Priority to EP97950228A priority patent/EP0941090A1/en
Priority to AU53262/98A priority patent/AU716575B2/en
Priority to JP10525294A priority patent/JP2000507618A/en
Priority to HU0001386A priority patent/HUP0001386A3/en
Priority to MYPI97005848A priority patent/MY132819A/en
Priority to NZ335750A priority patent/NZ335750A/en
Publication of FR2756736A1 publication Critical patent/FR2756736A1/en
Application granted granted Critical
Publication of FR2756736B1 publication Critical patent/FR2756736B1/en
Priority to YU23099A priority patent/YU23099A/en
Priority to IS5062A priority patent/IS5062A/en
Priority to NO992724A priority patent/NO992724L/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
FR9614957A 1996-12-05 1996-12-05 PHARMACEUTICAL COMPOSITIONS CONTAINING N-SULFONYL INDOLINE DERIVATIVES Expired - Fee Related FR2756736B1 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR9614957A FR2756736B1 (en) 1996-12-05 1996-12-05 PHARMACEUTICAL COMPOSITIONS CONTAINING N-SULFONYL INDOLINE DERIVATIVES
DZ970212A DZ2362A1 (en) 1996-12-05 1997-12-03 Pharmaceutical compositions containing n-sulfonyl indoline derivatives
IL12993697A IL129936A0 (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing n-sulphonyl indolin derivatives
ZA9710919A ZA9710919B (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing N-sulphony-lindole derivatives
RU99114019/14A RU2174394C2 (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing derivatives of n-sulfonylindoline
PCT/FR1997/002210 WO1998024430A1 (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing n-sulphonyl indolin derivatives
TR1999/01702T TR199901702T2 (en) 1996-12-05 1997-12-04 N-Sulfonilindolin t�revleri i�eren farmas�tik bile�imler.
CO97071118A CO4910129A1 (en) 1996-12-05 1997-12-04 PHARMACEUTICAL COMPOSITIONS CONTAINING DERIVATIVES OF N-SULFONIL INDOLINA
EEP199900206A EE9900206A (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing N-sulfonylindoline derivatives
SK755-99A SK75599A3 (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing n-sulphonyl indolin derivatives
KR1019997004983A KR20000069308A (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing n-sulphonyl indolin derivatives
BR9712406-0A BR9712406A (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing n-sufonil indoline derivatives
IDW990445D ID23373A (en) 1996-12-05 1997-12-04 PHARMACEUTICAL COMPOSITIONS THAT CONTAIN N-SULFONYLINDOLIN DEPOSITS
ARP970105696A AR009651A1 (en) 1996-12-05 1997-12-04 SOLUBILIZING / STABILIZING COMPOSITION ANHYDRABLE, EMULSIONABLE OR MICROEMULSIONABLE IN WATER, FOR THE SOLUBILIZATION OF N-SULFONIL INDOLINE HYDROPHOBIC DERIVATIVES, MICROEMULSULABLE, CAUSABLE, AND EMULSIBLE PHARMACEUTICAL COMPOSITION
CN97180304A CN1239887A (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing N-sulphonyl indolin derivatives
EP97950228A EP0941090A1 (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing n-sulphonyl indolin derivatives
AU53262/98A AU716575B2 (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing N-sulphonylindoline derivatives
JP10525294A JP2000507618A (en) 1996-12-05 1997-12-04 Pharmaceutical composition containing N-sulfonylindoline derivative
HU0001386A HUP0001386A3 (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing n-sulphonyl indolin derivatives
MYPI97005848A MY132819A (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing n-sulphonylindoline derivatives
NZ335750A NZ335750A (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing N-sulphonyl indoline derivatives and a solubilizing/stabilizing system having either a nonionic hydrophilic compound having amphiphilic and surfactant properties or a mixture of an amphiphilic compound and a nonionic hydrophilic surfactant
CA002273990A CA2273990A1 (en) 1996-12-05 1997-12-04 Pharmaceutical compositions containing n-sulphonyl indolin derivatives
YU23099A YU23099A (en) 1996-12-05 1999-05-26 Pharmaceutical compositions containing n-sulphonyl indolin derivatives
IS5062A IS5062A (en) 1996-12-05 1999-06-01 Medicinal preparations containing N-sulfonylindoline derivatives
NO992724A NO992724L (en) 1996-12-05 1999-06-04 Pharmaceutical mixtures containing N-sulfonyl-indoline derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9614957A FR2756736B1 (en) 1996-12-05 1996-12-05 PHARMACEUTICAL COMPOSITIONS CONTAINING N-SULFONYL INDOLINE DERIVATIVES

Publications (2)

Publication Number Publication Date
FR2756736A1 FR2756736A1 (en) 1998-06-12
FR2756736B1 true FR2756736B1 (en) 1999-03-05

Family

ID=9498376

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9614957A Expired - Fee Related FR2756736B1 (en) 1996-12-05 1996-12-05 PHARMACEUTICAL COMPOSITIONS CONTAINING N-SULFONYL INDOLINE DERIVATIVES

Country Status (25)

Country Link
EP (1) EP0941090A1 (en)
JP (1) JP2000507618A (en)
KR (1) KR20000069308A (en)
CN (1) CN1239887A (en)
AR (1) AR009651A1 (en)
AU (1) AU716575B2 (en)
BR (1) BR9712406A (en)
CA (1) CA2273990A1 (en)
CO (1) CO4910129A1 (en)
DZ (1) DZ2362A1 (en)
EE (1) EE9900206A (en)
FR (1) FR2756736B1 (en)
HU (1) HUP0001386A3 (en)
ID (1) ID23373A (en)
IL (1) IL129936A0 (en)
IS (1) IS5062A (en)
MY (1) MY132819A (en)
NO (1) NO992724L (en)
NZ (1) NZ335750A (en)
RU (1) RU2174394C2 (en)
SK (1) SK75599A3 (en)
TR (1) TR199901702T2 (en)
WO (1) WO1998024430A1 (en)
YU (1) YU23099A (en)
ZA (1) ZA9710919B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2786486B3 (en) * 1998-11-16 2000-12-08 Sanofi Sa PROCESS FOR THE PREPARATION OF (2S) -1 - [(2R, 3S) -5-CHLORO-3- (2- CHLOROPHENYL) -1- (3,4-DIMETHOXY BENZENESULFONYL) -3-HYDROXY- 2,3-DIHYDRO- 1H-INDOLE-2-CARBONYL] PYRROLIDINE-2-CARBOXAMIDE, ITS SOLVATES AND / OR HYDRATES
DE19913692A1 (en) * 1999-03-25 2000-09-28 Basf Ag Mechanically stable pharmaceutical dosage forms containing liquid or semi-solid surface-active substances
US6437006B1 (en) 1999-09-27 2002-08-20 American Cyanamid Company Pharmaceutical carrier formulation
WO2001034119A2 (en) 1999-11-12 2001-05-17 Abbott Laboratories Inhibitors of crystallization in a solid dispersion
FR2805992A1 (en) * 2000-03-08 2001-09-14 Sanofi Synthelabo Oral administration of N-sulfonyl-indoline derivative to treat central nervous system, cardiovascular or gastric disorders, using polyethylene glycol, polysorbate and poloxamer as solubilizers for high bioavailability
DE10026698A1 (en) 2000-05-30 2001-12-06 Basf Ag Self-emulsifying active ingredient formulation and use of this formulation
ITMI20011338A1 (en) * 2001-06-26 2002-12-26 Farmatron Ltd ORAL PHARMACEUTICAL COMPOSITIONS WITH IMMEDIATE RELEASE OF THE ACTIVE INGREDIENT
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
UA119324C2 (en) * 2013-04-02 2019-06-10 Теміс Медікер Лімітед Compositions of pharmaceutical actives containing diethylene glycol monoethyl ether or other alkyl derivatives
KR102139339B1 (en) * 2013-06-24 2020-07-29 주식회사 엘지생활건강 Cosmetic composition which has improved solubility comprising indole compound
KR102139338B1 (en) * 2013-06-24 2020-07-29 주식회사 엘지생활건강 Cosmetic composition which has improved solubility comprising indole compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3237814A1 (en) * 1982-10-12 1984-04-12 Warner-Lambert Co., 07950 Morris Plains, N.J. WATER-FREE EMULSIONS AND USE THEREOF
FR2679903B1 (en) * 1991-08-02 1993-12-03 Elf Sanofi DERIVATIVES OF N-SULFONYL INDOLINE CARRYING AN AMIDIC FUNCTION, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME.

Also Published As

Publication number Publication date
IS5062A (en) 1999-06-01
KR20000069308A (en) 2000-11-25
NO992724D0 (en) 1999-06-04
ZA9710919B (en) 1999-06-04
CN1239887A (en) 1999-12-29
HUP0001386A2 (en) 2001-04-28
ID23373A (en) 2000-04-20
CA2273990A1 (en) 1998-06-11
RU2174394C2 (en) 2001-10-10
CO4910129A1 (en) 2000-04-24
FR2756736A1 (en) 1998-06-12
WO1998024430A1 (en) 1998-06-11
DZ2362A1 (en) 2002-12-28
EP0941090A1 (en) 1999-09-15
SK75599A3 (en) 2000-08-14
BR9712406A (en) 1999-08-31
EE9900206A (en) 1999-12-15
MY132819A (en) 2007-10-31
JP2000507618A (en) 2000-06-20
AU716575B2 (en) 2000-03-02
IL129936A0 (en) 2000-02-29
YU23099A (en) 1999-11-22
TR199901702T2 (en) 1999-09-21
AR009651A1 (en) 2000-04-26
NZ335750A (en) 2001-06-29
AU5326298A (en) 1998-06-29
HUP0001386A3 (en) 2002-03-28
NO992724L (en) 1999-06-04

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse