NO985667L - FremgangsmÕte for fremstilling av medikamentkompleks - Google Patents
FremgangsmÕte for fremstilling av medikamentkompleksInfo
- Publication number
- NO985667L NO985667L NO985667A NO985667A NO985667L NO 985667 L NO985667 L NO 985667L NO 985667 A NO985667 A NO 985667A NO 985667 A NO985667 A NO 985667A NO 985667 L NO985667 L NO 985667L
- Authority
- NO
- Norway
- Prior art keywords
- spacer
- drug compound
- bound
- carboxyl groups
- polysaccharide derivative
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14452296 | 1996-06-06 | ||
| PCT/JP1997/001915 WO1997046261A1 (en) | 1996-06-06 | 1997-06-05 | Process for producing drug complexes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO985667D0 NO985667D0 (no) | 1998-12-04 |
| NO985667L true NO985667L (no) | 1999-02-04 |
| NO323626B1 NO323626B1 (no) | 2007-06-18 |
Family
ID=15364300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19985667A NO323626B1 (no) | 1996-06-06 | 1998-12-04 | Fremgangsmate for fremstilling av et medikamentkompleks |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6291671B1 (no) |
| EP (1) | EP0955064B1 (no) |
| JP (1) | JP4137184B2 (no) |
| CN (1) | CN1227034C (no) |
| AT (1) | ATE273716T1 (no) |
| AU (1) | AU723442B2 (no) |
| CA (1) | CA2257233A1 (no) |
| DE (1) | DE69730352T2 (no) |
| DK (1) | DK0955064T3 (no) |
| EA (1) | EA001897B1 (no) |
| ES (1) | ES2229355T3 (no) |
| ID (1) | ID17243A (no) |
| NO (1) | NO323626B1 (no) |
| PT (1) | PT955064E (no) |
| TW (1) | TW409058B (no) |
| WO (1) | WO1997046261A1 (no) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW527183B (en) | 1996-06-06 | 2003-04-11 | Daiichi Seiyaku Co | Drug complex |
| CA2333321A1 (en) * | 1998-05-22 | 1999-12-02 | Daiichi Pharmaceutical Co., Ltd. | Drug complex |
| MXPA02012791A (es) * | 2000-06-29 | 2003-12-11 | Daiichi Seiyaku Co | Compuestos dds y metodo para prepararlo. |
| US20040234497A1 (en) * | 2001-05-04 | 2004-11-25 | Yi Luo | Hyaluronic acid containing bioconjugates:targeted delivery of anti-cancer drugs to cancer cells |
| US20030049253A1 (en) * | 2001-08-08 | 2003-03-13 | Li Frank Q. | Polymeric conjugates for delivery of MHC-recognized epitopes via peptide vaccines |
| US20050169883A1 (en) * | 2002-05-06 | 2005-08-04 | Prestwich Glenn D. | Preblocking with non-ha gags increases effectiveness of ha conjugated anticancer agents |
| US7691830B2 (en) * | 2005-02-17 | 2010-04-06 | Clive Elson | Method and composition for treatment of a mucosal tissue disorder |
| CA2912012C (en) | 2005-05-05 | 2018-05-29 | Sensient Flavors Inc. | Production of beta-glucans and mannans |
| WO2007004675A1 (ja) * | 2005-07-06 | 2007-01-11 | Seikagaku Corporation | 薬剤導入光架橋ヒアルロン酸誘導体ゲル |
| ITPD20050242A1 (it) | 2005-08-03 | 2007-02-04 | Fidia Farmaceutici | Bioconiugati antitumorali dell'acido ialuronico o dei suoi derivati, ottenibili per coniugazione chimica diretta o indiretta, e loro impiego in campo farmaceutico |
| CN1973902B (zh) * | 2006-12-12 | 2010-11-10 | 东北师范大学 | 以人参多糖为载体的抗肿瘤药物阿霉素复合物及制备方法 |
| US9895449B2 (en) | 2010-05-25 | 2018-02-20 | Syndevrx, Inc. | Polymer-conjugated MetAP2 inhibitors, and therapeutic methods of use thereof |
| WO2011150022A2 (en) | 2010-05-25 | 2011-12-01 | Syndevrx, Inc. | Polymer-conjugated metap2 inhibitors, and therapeutic methods of use thereof |
| SI3342785T1 (sl) | 2012-10-11 | 2020-02-28 | Daiichi Sankyo Company, Limited | Povezovalci za konjugate protitelesa in zdravila |
| WO2014061277A1 (ja) | 2012-10-19 | 2014-04-24 | 第一三共株式会社 | 親水性構造を含むリンカーで結合させた抗体－薬物コンジュゲート |
| ES2749746T3 (es) | 2013-04-10 | 2020-03-23 | Syndevrx Inc | Inhibidores de fumagilol metap2 modificados o conjugados con polímeros para uso en el tratamiento de la obesidad |
| WO2015071841A1 (en) | 2013-11-12 | 2015-05-21 | Druggability Technologies Holdings Limited | Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
| WO2015098099A1 (ja) | 2013-12-25 | 2015-07-02 | 第一三共株式会社 | 抗ｔｒｏｐ２抗体－薬物コンジュゲート |
| RS62618B1 (sr) | 2014-01-31 | 2021-12-31 | Daiichi Sankyo Co Ltd | Anti-her2 antitelo-lek konjugat |
| EP3129063B1 (en) | 2014-04-10 | 2021-01-27 | Daiichi Sankyo Company, Limited | Anti-her3 antibody-drug conjugate |
| WO2015155976A1 (ja) | 2014-04-10 | 2015-10-15 | 第一三共株式会社 | 抗ｈｅｒ２抗体－薬物コンジュゲート |
| BR112017027690A2 (pt) | 2015-06-29 | 2018-10-09 | Daiichi Sankyo Co Ltd | método para produção de uma composição de conjugado anticorpo-fármaco, e, composição de conjugado anticorpo-fármaco |
| MX2018006904A (es) | 2015-12-10 | 2018-08-24 | Syndevrx Inc | Derivados de fumagilol y polimorfos de los mismos. |
| CN114225045A (zh) | 2016-01-11 | 2022-03-25 | 辛德弗雷克斯公司 | 代谢功能障碍引起的肿瘤的治疗 |
| US11273155B2 (en) | 2016-12-12 | 2022-03-15 | Daiichi Sankyo Company, Limited | Combination of antibody-drug conjugate and immune checkpoint inhibitor |
| IL268102B1 (en) | 2017-01-17 | 2024-08-01 | Daiichi Sankyo Co Ltd | Anti-GPR 20 antibody and anti-GPR 20 antibody-drug conjugate |
| TWI794230B (zh) | 2017-05-15 | 2023-03-01 | 日商第一三共股份有限公司 | 抗ｃｄｈ６抗體及抗ｃｄｈ６抗體-藥物結合物、以及其製造方法 |
| BR112020003646A2 (pt) | 2017-08-31 | 2020-09-01 | Daiichi Sankyo Company, Limited | cristais, métodos para produção de cristais e de um conjugado anticorpo-fármaco, e, sal. |
| SG11202001514XA (en) | 2017-08-31 | 2020-03-30 | Daiichi Sankyo Co Ltd | Novel method for producing antibody-drug conjugate |
| SI3794042T1 (sl) | 2018-05-18 | 2024-07-31 | Daiichi Sankyo Co., Ltd. | Konjugat protitelesa anti-MUC1-exatecan in citotoksično sredstvo |
| EP3870231A1 (en) | 2018-10-26 | 2021-09-01 | Syndevrx, Inc. | Biomarkers of metap2 inhibitors and applications thereof |
| US11634508B2 (en) | 2019-07-10 | 2023-04-25 | Cybrexa 2, Inc. | Peptide conjugates of cytotoxins as therapeutics |
| EP3996749A1 (en) | 2019-07-10 | 2022-05-18 | Cybrexa 3, Inc. | Peptide conjugates of microtubule-targeting agents as therapeutics |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2093697A (en) * | 1980-09-03 | 1982-09-08 | Kyosei Pharmaceutical Co Ltd | Agent for alimentary canal |
| JPS5746920A (en) * | 1980-09-03 | 1982-03-17 | Kyosei Seiyaku Kk | Drug for digestive tract |
| JPS59220197A (ja) * | 1983-05-30 | 1984-12-11 | Snow Brand Milk Prod Co Ltd | 新規な含窒素多糖体およびその製造方法 |
| JP2604930B2 (ja) * | 1990-12-14 | 1997-04-30 | 株式会社ディ・ディ・エス研究所 | ヒアルロン酸およびコンドロイチン誘導体 |
| CA2059693C (en) * | 1991-01-28 | 2003-08-19 | Peter J. Kniskern | Polysaccharide antigens from streptococcus pneumoniae |
| DE69225542T2 (de) | 1991-02-21 | 1998-09-10 | Drug Delivery System Inst Ltd | Carboxymethylmannoglukan und derivate davon |
| JP3359955B2 (ja) | 1992-07-16 | 2002-12-24 | 第一製薬株式会社 | 抗腫瘍剤 |
| ES2149867T3 (es) | 1993-02-26 | 2000-11-16 | Drug Delivery System Inst Ltd | Derivados de polisacaridos y soportes para farmacos. |
| JPH0784481A (ja) | 1993-06-26 | 1995-03-31 | Ricoh Co Ltd | 画像形成装置 |
| SG50747A1 (en) | 1995-08-02 | 1998-07-20 | Tanabe Seiyaku Co | Comptothecin derivatives |
| TW527183B (en) | 1996-06-06 | 2003-04-11 | Daiichi Seiyaku Co | Drug complex |
| US6299881B1 (en) * | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
-
1997
- 1997-05-31 TW TW086107456A patent/TW409058B/zh not_active IP Right Cessation
- 1997-06-05 AT AT97924326T patent/ATE273716T1/de not_active IP Right Cessation
- 1997-06-05 CN CNB971971153A patent/CN1227034C/zh not_active Expired - Fee Related
- 1997-06-05 EP EP97924326A patent/EP0955064B1/en not_active Expired - Lifetime
- 1997-06-05 US US09/147,341 patent/US6291671B1/en not_active Expired - Fee Related
- 1997-06-05 EA EA199900002A patent/EA001897B1/ru not_active IP Right Cessation
- 1997-06-05 CA CA002257233A patent/CA2257233A1/en not_active Abandoned
- 1997-06-05 DK DK97924326T patent/DK0955064T3/da active
- 1997-06-05 WO PCT/JP1997/001915 patent/WO1997046261A1/ja active IP Right Grant
- 1997-06-05 ID IDP971929A patent/ID17243A/id unknown
- 1997-06-05 DE DE69730352T patent/DE69730352T2/de not_active Expired - Lifetime
- 1997-06-05 PT PT97924326T patent/PT955064E/pt unknown
- 1997-06-05 AU AU29788/97A patent/AU723442B2/en not_active Ceased
- 1997-06-05 ES ES97924326T patent/ES2229355T3/es not_active Expired - Lifetime
- 1997-06-05 JP JP50042298A patent/JP4137184B2/ja not_active Expired - Fee Related
-
1998
- 1998-12-04 NO NO19985667A patent/NO323626B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1227500A (zh) | 1999-09-01 |
| CN1227034C (zh) | 2005-11-16 |
| DE69730352D1 (de) | 2004-09-23 |
| ATE273716T1 (de) | 2004-09-15 |
| NO323626B1 (no) | 2007-06-18 |
| ID17243A (id) | 1997-12-11 |
| EP0955064A1 (en) | 1999-11-10 |
| NO985667D0 (no) | 1998-12-04 |
| TW409058B (en) | 2000-10-21 |
| AU723442B2 (en) | 2000-08-24 |
| DE69730352T2 (de) | 2005-09-08 |
| EP0955064B1 (en) | 2004-08-18 |
| ES2229355T3 (es) | 2005-04-16 |
| JP4137184B2 (ja) | 2008-08-20 |
| AU2978897A (en) | 1998-01-05 |
| US6291671B1 (en) | 2001-09-18 |
| DK0955064T3 (da) | 2004-12-06 |
| CA2257233A1 (en) | 1997-12-11 |
| EA001897B1 (ru) | 2001-10-22 |
| EA199900002A1 (ru) | 1999-08-26 |
| EP0955064A4 (en) | 2000-12-06 |
| PT955064E (pt) | 2004-10-29 |
| WO1997046261A1 (en) | 1997-12-11 |
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