NO984447L - FremgangsmÕte ved fremstilling av optisk aktive 2-amino-w-oksoalkanonsyrederivater - Google Patents

FremgangsmÕte ved fremstilling av optisk aktive 2-amino-w-oksoalkanonsyrederivater

Info

Publication number
NO984447L
NO984447L NO984447A NO984447A NO984447L NO 984447 L NO984447 L NO 984447L NO 984447 A NO984447 A NO 984447A NO 984447 A NO984447 A NO 984447A NO 984447 L NO984447 L NO 984447L
Authority
NO
Norway
Prior art keywords
amino acid
amino
acid amide
preparation
converted
Prior art date
Application number
NO984447A
Other languages
English (en)
Other versions
NO984447D0 (no
Inventor
Wilhelmus Hubertus Jos Boesten
Quirinus Bernardus Broxterman
Marcus Joseph Maria Plaum
Original Assignee
Dsm Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19765731&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO984447(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dsm Nv filed Critical Dsm Nv
Publication of NO984447D0 publication Critical patent/NO984447D0/no
Publication of NO984447L publication Critical patent/NO984447L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/06—Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures

Abstract

Fremgangsmåte ved fremstilling av et (S)-2-amin-co- oksoalkanoinsyrederivat hvori det korresponderende aldehyd omdannes til det korresponderende acetal- beskyttede aldehyd, det acetal-beskyttede aldehyd omdannes til det korresponderende aminonitril, ami- nonitrilet omdannes til det korresponderende amino- syreamid, aminosyreamidet underkastes en enzyma- tisk, enantioselektiv hydrolyse hvori R-enantio- meren av aminosyreamidet gjenblir og S-enantiomeren omdannes til S-aminosyren, og S-aminosyren isole- res. Fortrinnsvis behandles reaksjonsblandingen erholdt etter omdannelse av aminonitrilet til aminosyreamid med et benzaldehyd, hvorved Schiff- basen av aminosyreamidet dannes, Schiff-basen sepa- reres og pmdannes til det frie aminosyreamid.
NO984447A 1997-09-25 1998-09-24 FremgangsmÕte ved fremstilling av optisk aktive 2-amino-w-oksoalkanonsyrederivater NO984447L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL1007113A NL1007113C2 (nl) 1997-09-25 1997-09-25 Werkwijze voor de bereiding van optisch actieve 2-amino-omega- oxoalkaanzuurderivaten.

Publications (2)

Publication Number Publication Date
NO984447D0 NO984447D0 (no) 1998-09-24
NO984447L true NO984447L (no) 1999-03-26

Family

ID=19765731

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984447A NO984447L (no) 1997-09-25 1998-09-24 FremgangsmÕte ved fremstilling av optisk aktive 2-amino-w-oksoalkanonsyrederivater

Country Status (15)

Country Link
EP (1) EP0905257B2 (no)
JP (1) JPH11236361A (no)
KR (1) KR19990030181A (no)
CN (1) CN1218797A (no)
AT (1) ATE267265T1 (no)
CA (1) CA2247952A1 (no)
CZ (1) CZ308698A3 (no)
DE (1) DE69823941T3 (no)
ES (1) ES2221974T5 (no)
HU (1) HU220580B1 (no)
IL (1) IL126313A (no)
NL (1) NL1007113C2 (no)
NO (1) NO984447L (no)
SG (1) SG74077A1 (no)
TW (1) TW430641B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999041249A1 (fr) * 1998-02-17 1999-08-19 Daicel Chemical Industries, Ltd. Procedes de production de monoacetals de dialdehyde
US6174711B1 (en) 1998-07-05 2001-01-16 Mitsubishi Gas Chemical Company Method for producing L-allysine acetal
IL140861A (en) * 1998-07-15 2004-06-01 Bristol Myers Squibb Co Dioxolane pentanoic acid and processes for the preparation thereof
US6620600B2 (en) 2000-09-15 2003-09-16 Bristol-Myers Squibb Co. Enzymatic resolution of aryl and thio-substituted acids
JP4851668B2 (ja) * 2001-09-13 2012-01-11 株式会社日本ファインケム ジアルデヒドモノエチレンアセタールアミノニトリルの製造方法
JP2003081964A (ja) * 2001-09-13 2003-03-19 Japan Hydrazine Co Inc α−アミノ酸アミドの製造方法
DE10155065A1 (de) * 2001-11-09 2003-05-22 Degussa Verfahren zur Kristallisation von Oxonorleucinacetal
JP4412279B2 (ja) * 2003-04-02 2010-02-10 田辺三菱製薬株式会社 光学活性α−アミノニトリル化合物の製法
CN114988989A (zh) * 2021-03-02 2022-09-02 汉淇生医科技有限公司 戊二醛与1,6-己二醇之加成物、包含其之医药组合物及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5142111B2 (no) * 1971-10-02 1976-11-13
DE3043159C2 (de) * 1980-11-15 1982-12-09 Degussa Ag, 6000 Frankfurt Cyclische Acetale des Glutaminsäure-γ-semialdehyds, Verfahren zu deren Herstellung und ihre Verwendung
DE3043252C2 (de) * 1980-11-15 1982-12-02 Degussa Ag, 6000 Frankfurt Cyclische Acetale von N-Acylglutaminsäure -γ- semialdehyden, Verfahren zu deren Herstellung und ihre Verwendung
JPH02501531A (ja) * 1987-08-17 1990-05-31 ノヴオ―ノルデイスク　アー／エス 有機化学品の製法
EP0383403A1 (en) * 1989-02-16 1990-08-22 Stamicarbon B.V. Process for preparation of organic chemicals
US5332826A (en) * 1993-10-13 1994-07-26 Eastman Kodak Company Process for preparing aminoacetonitriles in one vessel
JPH10295392A (ja) † 1997-04-22 1998-11-10 Kanegafuchi Chem Ind Co Ltd Ｌ−アルリジンアセタールの製造方法

Also Published As

Publication number Publication date
IL126313A0 (en) 1999-05-09
EP0905257B1 (en) 2004-05-19
SG74077A1 (en) 2000-07-18
EP0905257A1 (en) 1999-03-31
CN1218797A (zh) 1999-06-09
HU220580B1 (hu) 2002-03-28
ES2221974T5 (es) 2007-10-16
EP0905257B2 (en) 2007-02-21
NL1007113C2 (nl) 1999-03-26
DE69823941T3 (de) 2007-10-18
ES2221974T3 (es) 2005-01-16
HU9802146D0 (en) 1998-12-28
HUP9802146A3 (en) 1999-09-28
DE69823941D1 (de) 2004-06-24
CZ308698A3 (cs) 1999-05-12
CA2247952A1 (en) 1999-03-25
KR19990030181A (ko) 1999-04-26
JPH11236361A (ja) 1999-08-31
NO984447D0 (no) 1998-09-24
HUP9802146A2 (hu) 1999-04-28
TW430641B (en) 2001-04-21
ATE267265T1 (de) 2004-06-15
DE69823941T2 (de) 2005-08-11
IL126313A (en) 2001-04-30

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