NO984204L - Nye brodannete cykliske aminosyrer som farmas°ytiske midler - Google Patents

Nye brodannete cykliske aminosyrer som farmas°ytiske midler

Info

Publication number
NO984204L
NO984204L NO984204A NO984204A NO984204L NO 984204 L NO984204 L NO 984204L NO 984204 A NO984204 A NO 984204A NO 984204 A NO984204 A NO 984204A NO 984204 L NO984204 L NO 984204L
Authority
NO
Norway
Prior art keywords
amino acids
pct
cyclic amino
pharmaceutical agents
bridged cyclic
Prior art date
Application number
NO984204A
Other languages
English (en)
Norwegian (no)
Other versions
NO984204D0 (no
Inventor
Justin Stephen Bryans
David Christopher Horwell
Clare Octavia Kneen
Andrew Ian Morrell
Giles Stuart Ratcliffe
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO984204D0 publication Critical patent/NO984204D0/no
Publication of NO984204L publication Critical patent/NO984204L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/46—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing nine carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO984204A 1996-03-14 1998-09-11 Nye brodannete cykliske aminosyrer som farmas°ytiske midler NO984204L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1343396P 1996-03-14 1996-03-14
PCT/US1997/002401 WO1997033859A1 (en) 1996-03-14 1997-02-18 Novel bridged cyclic amino acids as pharmaceutical agents

Publications (2)

Publication Number Publication Date
NO984204D0 NO984204D0 (no) 1998-09-11
NO984204L true NO984204L (no) 1998-09-11

Family

ID=21759944

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984204A NO984204L (no) 1996-03-14 1998-09-11 Nye brodannete cykliske aminosyrer som farmas°ytiske midler

Country Status (18)

Country Link
US (1) US6020370A (de)
EP (1) EP0888285B1 (de)
JP (1) JP2000506862A (de)
KR (1) KR100487032B1 (de)
AT (1) ATE210629T1 (de)
AU (1) AU731279B2 (de)
BR (1) BR9708180A (de)
CZ (1) CZ287598A3 (de)
DE (1) DE69709070T2 (de)
EA (1) EA001214B1 (de)
ES (1) ES2169848T3 (de)
IL (1) IL125364A0 (de)
NO (1) NO984204L (de)
NZ (1) NZ331142A (de)
PL (1) PL185990B1 (de)
SK (1) SK282848B6 (de)
WO (1) WO1997033859A1 (de)
ZA (1) ZA972199B (de)

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US6465689B1 (en) 1997-09-18 2002-10-15 Warner-Lambert Company Stereoselective processes for the preparation of gabapentin analogues
US6984659B2 (en) 1997-11-18 2006-01-10 Klinikum Der Albert-Ludwigs Universitaet 2-pyrrolidinone derivatives substituted at position 4 for reducing the extracellular glutamate level
DE19751062A1 (de) * 1997-11-18 1999-07-08 Univ Ludwigs Albert An 4-Stellung substituierte 2-Pyrrolidinon-Derivate zur Verringerung des extrazellulären Glutamat-Spiegels
CN1495160A (zh) * 1997-12-16 2004-05-12 ��ʲ 1-取代-1-氨基甲基-环烷衍生物（＝加巴喷丁类似物）、其制备及其在治疗神经病方面的用途
BR9910697A (pt) 1998-05-26 2001-01-30 Warner Lambert Co Compostos aminoácidos comprimidos estruturalmente tendo afinidade à subunidade alfa2delta de um canal de cálcio
WO2000002592A1 (en) * 1998-07-09 2000-01-20 Warner-Lambert Company Pharmaceutical composition containinig gaba analogs and an antiviral agent to treat shingles
DE60034344T2 (de) 1999-07-22 2008-01-10 University Of Rochester Methode zur behandlung der symptome hormoneller veränderungen, einschliesslich hitzewallungen
JP2003528148A (ja) * 2000-03-28 2003-09-24 デロレンゾ、ロバート・ジェイ 損傷に際して神経細胞中に形成される新規カルシウム損傷電流の阻害は神経細胞死を抑制する
KR100785182B1 (ko) * 2000-06-26 2007-12-11 워너-램버트 캄파니 엘엘씨 수면 장애를 위한 가바펜틴 유사체
EP1343805A4 (de) 2000-10-06 2005-07-20 Xenoport Inc Von gallensäuren abgeleitete verbindungen für die bereitstellung anhaltender systemischer konzentrationen von arzneimitteln nach oraler verabreichung
EP1361847A2 (de) * 2000-10-06 2003-11-19 Xenoport, Inc. Gallensäurekonjugate zur bereitstellung anhaltender systemischer arneimittelkonzentrationen
GB2374595A (en) * 2001-04-19 2002-10-23 Warner Lambert Co Fused bicyclic or tricyclic amino acids
PL366406A1 (en) 2001-04-19 2005-01-24 Warner-Lambert Company Llc Fused bicyclic or tricyclic amino acids
US7232924B2 (en) * 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US6818787B2 (en) * 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
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EP1412324A4 (de) 2001-06-11 2004-09-29 Xenoport Inc Aminosäurekonjugate, die anhaltende systemische konzentrationen von gaba-analoga ergeben
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
AU2002316231A1 (en) * 2002-02-19 2003-09-29 Xenoport, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
WO2003080588A1 (en) 2002-03-20 2003-10-02 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
EP1549323A2 (de) * 2002-05-07 2005-07-06 A & D Bioscience, Inc. Konjugate mit einem wirkstoff für das zentrale nervensystem
WO2003099338A2 (en) * 2002-05-17 2003-12-04 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
AU2003297909A1 (en) * 2002-12-11 2004-06-30 Xenoport, Inc. Orally administered dosage forms of fused gaba analog prodrugs having reduced toxicity
US7060727B2 (en) 2002-12-11 2006-06-13 Xenoport, Inc. Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
DE60332387D1 (de) 2002-12-13 2010-06-10 Warner Lambert Co Alpha-2-delta-ligand zur behandlung vonsymptomen der unteren harnwege
EP1608357A4 (de) * 2003-03-31 2008-03-26 Xenoport Inc Behandlung oder prävention von hitzewallungen unter verwendung von prodrugs von gaba-analoga
KR20060119971A (ko) * 2003-09-11 2006-11-24 제노포트 인코포레이티드 Ｇａｂａ 유사체의 전구약물을 이용한 요실금의 치료및/또는 예방
CN1849153A (zh) 2003-09-12 2006-10-18 辉瑞大药厂 含有α－2－δ配体和5－羟色胺/去甲肾上腺素重摄取抑制剂的组合物
CN1871021B (zh) 2003-09-17 2010-07-28 什诺波特有限公司 用gaba类似物的前药治疗或预防多动腿综合征
SI1677767T1 (sl) 2003-10-14 2011-11-30 Xenoport Inc Kristalinična oblika analoga gama-aminomaslene kisline
DK1691811T3 (da) 2003-12-11 2014-10-20 Sunovion Pharmaceuticals Inc Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression
BRPI0517227B8 (pt) * 2004-11-04 2021-05-25 Xenoport Inc comprimido oral de liberação prolongada do ácido 1-{[alfa-isobutanoiloxietoxi)carbonil]amino metil}-1-cicloexano acético, e, uso do comprimido
WO2007070801A2 (en) * 2005-12-12 2007-06-21 Allaccem, Inc. Methods and systems for preparing antimicrobial films and coatings
US7727978B2 (en) 2006-08-24 2010-06-01 Bristol-Myers Squibb Company Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
MX2009006080A (es) * 2006-12-08 2009-07-14 Xenoport Inc Uso de profarmacos de analogos de gaba para el tratamiento de enfermedades.
RS51940B (en) 2006-12-22 2012-02-29 Recordati Ireland Limited Combined TH2δ LIGANAD THERAPY AND NSAID FOR LOWER URINARY TRACT DISORDERS
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Also Published As

Publication number Publication date
AU2127197A (en) 1997-10-01
ES2169848T3 (es) 2002-07-16
NZ331142A (en) 2001-04-27
NO984204D0 (no) 1998-09-11
BR9708180A (pt) 1999-07-27
EP0888285B1 (de) 2001-12-12
PL328800A1 (en) 1999-02-15
EA199800797A1 (ru) 1999-04-29
ATE210629T1 (de) 2001-12-15
IL125364A0 (en) 1999-03-12
DE69709070D1 (de) 2002-01-24
DE69709070T2 (de) 2002-06-20
KR19990087755A (ko) 1999-12-27
PL185990B1 (pl) 2003-09-30
SK124898A3 (en) 1999-02-11
US6020370A (en) 2000-02-01
ZA972199B (en) 1997-09-17
AU731279B2 (en) 2001-03-29
EP0888285A1 (de) 1999-01-07
WO1997033859A1 (en) 1997-09-18
EA001214B1 (ru) 2000-12-25
KR100487032B1 (ko) 2005-12-21
JP2000506862A (ja) 2000-06-06
CZ287598A3 (cs) 1999-02-17
SK282848B6 (sk) 2002-12-03

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