NO982906L - Heterosyklylkondenserte benzoylguanidiner, deres fremstilling og anvendelse som inhibitorer for den cellulµre Na+/H+-antiporter - Google Patents
Heterosyklylkondenserte benzoylguanidiner, deres fremstilling og anvendelse som inhibitorer for den cellulµre Na+/H+-antiporterInfo
- Publication number
- NO982906L NO982906L NO982906A NO982906A NO982906L NO 982906 L NO982906 L NO 982906L NO 982906 A NO982906 A NO 982906A NO 982906 A NO982906 A NO 982906A NO 982906 L NO982906 L NO 982906L
- Authority
- NO
- Norway
- Prior art keywords
- stands
- antiporter
- inhibitors
- cellular
- nha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19548708A DE19548708A1 (de) | 1995-12-23 | 1995-12-23 | Cyclische Sulfone |
| PCT/EP1996/005645 WO1997023476A1 (de) | 1995-12-23 | 1996-12-16 | HETEROCYCLYLKONDENSIERTE BENZOYLGUANIDINE, DEREN HERSTELLUNG UND DEREN VERWENDUNG ALS INHIBITOREN DES ZELLULÄREN Na+/H+-ANTIPORTERS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO982906L true NO982906L (no) | 1998-06-22 |
| NO982906D0 NO982906D0 (no) | 1998-06-22 |
Family
ID=7781400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO982906A NO982906D0 (no) | 1995-12-23 | 1998-06-22 | Heterosyklylkondenserte benzoylguanidiner, deres fremstilling og anvendelse som inhibitorer for den cellulµre Na+/H+-antiporter |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6028069A (xx) |
| EP (1) | EP0873335A1 (xx) |
| JP (1) | JP2000502663A (xx) |
| KR (1) | KR19990076675A (xx) |
| AR (1) | AR004402A1 (xx) |
| AU (1) | AU710048B2 (xx) |
| BR (1) | BR9612200A (xx) |
| CA (1) | CA2241143A1 (xx) |
| CZ (1) | CZ199798A3 (xx) |
| DE (1) | DE19548708A1 (xx) |
| HU (1) | HUP9802920A3 (xx) |
| NO (1) | NO982906D0 (xx) |
| PL (1) | PL327186A1 (xx) |
| RU (1) | RU2161616C2 (xx) |
| SK (1) | SK81598A3 (xx) |
| TW (1) | TW381091B (xx) |
| WO (1) | WO1997023476A1 (xx) |
| ZA (1) | ZA9610724B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4328352A1 (de) * | 1993-08-24 | 1995-03-02 | Hoechst Ag | Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| JP2002502414A (ja) * | 1997-06-02 | 2002-01-22 | 藤沢薬品工業株式会社 | 細胞中のＮａ▲上＋▼／Ｈ▲上＋▼交換の阻害剤としてのグアニジン誘導体 |
| US6730697B2 (en) * | 2002-02-07 | 2004-05-04 | Aventis Pharma Deutschland Gmbh | Dihydrothiaphenanthrenecarbonylguanidines: composition, process of making, and use as medicament or diagnostic aid |
| TW200614995A (en) * | 2004-11-10 | 2006-05-16 | Nicholas Piramal India Ltd | Tricyclic guanidine derivatives as sodium-proton exchange inhibitors |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| DE59305042D1 (de) * | 1992-09-22 | 1997-02-20 | Hoechst Ag | Benzoylguanidine, Verfahren zu ihrer Herstellung, sowie ihre Verwendung als Antiarrhythmika |
| PT590455E (pt) * | 1992-09-28 | 2001-04-30 | Hoechst Ag | 1(2h)-isoquinolinas substituidas anti-arritmicas e cardioprotectoras processo para a sua preparacao medicamento contendo estes compostos e sua utilizacao para a preparacao de um medicamento para o combate de falhas cardiacas |
| US5514801A (en) * | 1992-12-29 | 1996-05-07 | Monsanto Company | Cyclic sulfone containing retroviral protease inhibitors |
| CA2121391A1 (en) * | 1993-04-28 | 1994-10-29 | Atsuyuki Kojima | Indoloylguanidine derivatives |
| DE4317076A1 (de) * | 1993-05-21 | 1994-11-24 | Bayer Ag | Benzthiophencarbonsäureamid-S-oxide |
| US5607898A (en) * | 1993-08-02 | 1997-03-04 | Idemitsu Kosan Company, Ltd. | Pyrazole derivatives |
| EP0639573A1 (de) * | 1993-08-03 | 1995-02-22 | Hoechst Aktiengesellschaft | Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament |
| US5627194A (en) * | 1993-11-17 | 1997-05-06 | Allelix Biopharmaceuticals Inc. | Anti-viral guanidino-substituted compounds |
| DE4344550A1 (de) * | 1993-12-24 | 1995-06-29 | Hoechst Ag | Substituierte 1-Oxo-1,2-dihydro-isochinolinoyl- und 1,1-Dioxo-2H-1,2-benzothiazinoylguanidine, Verfahrenzu ihrer Herstellung, ihre Verwendung als Medikamentt oder Diagnostikum sowie sie enthaltendes Medikamen |
| DE69525763T2 (de) * | 1994-04-11 | 2002-10-02 | Chugai Seiyaku K.K., Tokio/Tokyo | 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENE, DIE LDL OXIDATION HEMMEN |
| DE4412334A1 (de) * | 1994-04-11 | 1995-10-19 | Hoechst Ag | Substituierte N-Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US5863936A (en) * | 1995-04-18 | 1999-01-26 | Geron Corporation | Telomerase inhibitors |
| US5821250A (en) * | 1996-02-01 | 1998-10-13 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| FR2762598A1 (fr) * | 1997-04-25 | 1998-10-30 | Adir | Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennnent |
-
1995
- 1995-12-23 DE DE19548708A patent/DE19548708A1/de not_active Withdrawn
-
1996
- 1996-10-20 AR ARP960105800A patent/AR004402A1/es unknown
- 1996-11-19 TW TW085114208A patent/TW381091B/zh active
- 1996-12-16 US US09/091,652 patent/US6028069A/en not_active Expired - Fee Related
- 1996-12-16 EP EP96943131A patent/EP0873335A1/de not_active Withdrawn
- 1996-12-16 RU RU98114077/04A patent/RU2161616C2/ru active
- 1996-12-16 KR KR1019980704787A patent/KR19990076675A/ko not_active Application Discontinuation
- 1996-12-16 AU AU11960/97A patent/AU710048B2/en not_active Ceased
- 1996-12-16 JP JP9523281A patent/JP2000502663A/ja active Pending
- 1996-12-16 BR BR9612200A patent/BR9612200A/pt not_active Application Discontinuation
- 1996-12-16 PL PL96327186A patent/PL327186A1/xx unknown
- 1996-12-16 SK SK815-98A patent/SK81598A3/sk unknown
- 1996-12-16 CA CA002241143A patent/CA2241143A1/en not_active Abandoned
- 1996-12-16 WO PCT/EP1996/005645 patent/WO1997023476A1/de not_active Application Discontinuation
- 1996-12-16 HU HU9802920A patent/HUP9802920A3/hu unknown
- 1996-12-16 CZ CZ981997A patent/CZ199798A3/cs unknown
- 1996-12-19 ZA ZA9610724A patent/ZA9610724B/xx unknown
-
1998
- 1998-06-22 NO NO982906A patent/NO982906D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MX9804972A (es) | 1998-09-30 |
| HUP9802920A2 (hu) | 2000-05-28 |
| BR9612200A (pt) | 1999-07-13 |
| NO982906D0 (no) | 1998-06-22 |
| PL327186A1 (en) | 1998-11-23 |
| AU1196097A (en) | 1997-07-17 |
| KR19990076675A (ko) | 1999-10-15 |
| AU710048B2 (en) | 1999-09-09 |
| HUP9802920A3 (en) | 2000-12-28 |
| US6028069A (en) | 2000-02-22 |
| AR004402A1 (es) | 1998-11-04 |
| RU2161616C2 (ru) | 2001-01-10 |
| CA2241143A1 (en) | 1997-07-03 |
| SK81598A3 (en) | 1999-01-11 |
| CZ199798A3 (cs) | 1998-10-14 |
| TW381091B (en) | 2000-02-01 |
| JP2000502663A (ja) | 2000-03-07 |
| WO1997023476A1 (de) | 1997-07-03 |
| EP0873335A1 (de) | 1998-10-28 |
| ZA9610724B (en) | 1997-06-26 |
| DE19548708A1 (de) | 1997-06-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69702605D1 (de) | Fotoerzeugung von Aminen aus alpha-Aminoacetophenonen | |
| NO20053246L (no) | Kondensert 1,3-dihydroimidazol-ringforbindelse. | |
| CY1113782T1 (el) | Παραγωγα 11-υδροξυ-5η-πυρρολο[2,1-c][1,4]βενζοδιαζεπιν-5-ονης ως ενδιαμεσα κλειδια για την παρασκευη c2 υποκατεστημενων πυρρολοβενζοδιαζεπινων | |
| NO20055226L (no) | Fremgangsmate for fremstilling av N-substituerte 2-cyanopyrrolidoner | |
| BRPI0211844B8 (pt) | composto de ácido fenóxi-acético ou um de seus sais farmaceuticamente aceitáveis, e, composição farmacêutica | |
| HUP0201646A2 (hu) | Új alfa-aminosav vegyületek, eljárás ezek előállítására, és ezeket tartalmazó gyógyászati készítmények | |
| NO950813L (no) | Acetamider | |
| NO982906L (no) | Heterosyklylkondenserte benzoylguanidiner, deres fremstilling og anvendelse som inhibitorer for den cellulµre Na+/H+-antiporter | |
| HUP0302193A2 (hu) | 1,4-Diazabiciklo[3.2.2]nonán-benzoxazol,-benzotiazol és -benzimidazol-származékok, előállításuk és ezeket tartalmazó gyógyszerkészítmények | |
| DE60200937D1 (de) | 4-aminobenzopyranderivate | |
| NO20073330L (no) | Sulfanylsubstituerte fenylmetanoner som glycintransportor 1 (glyt-1) inhibitorer for behandling av nevrologiske og nevropsykiatriske forstyrrelser | |
| NO20002490L (no) | FremgangsmÕte for fremstilling av 1,4-dihydropyridiner og forbindelser anvendt ved denne fremgangsmÕten | |
| BR0207830A (pt) | Compostos de carbamato para uso em prevenir ou tratar distúrbios de ansiedade | |
| NO20085155L (no) | Substituerte fenylmetanon-derivativer | |
| FI894783A (fi) | Substituerade aromatiska foereningar med verkan pao det centrala nervsystemet. | |
| EA200200807A1 (ru) | Аминокислотные соединения и их применение в качестве ингибиторов nep, ace и ece | |
| NO943961L (no) | Sykliske aminderivater | |
| NO961537D0 (no) | Salpetersyreestere fra derivater av 2-(2,6-dihalofenylamino)-fenylacetoksyeddiksyre, og deres fremstillingsprosedyrer | |
| BR0213176A (pt) | Derivados microbiocidas de n-fenil-n-[4-(4-piridil)-2-pirimidin-2-il]amina | |
| TR200002485T2 (tr) | N-Sülfonil ve N-Sülfinil Fenilglisinamid | |
| KR910006257A (ko) | 안트라닐산 유도체 및 이를 함유하는 구충제 조성물 | |
| ATE371661T1 (de) | Tumorhemmende derivate von et-743 | |
| EA200000116A1 (ru) | Противогрибковые соединения на основе 2,4,4-тризамещенных-1,3-диоксоланов | |
| BR0013947A (pt) | Ciclo-propano-carboxamida, composição, processo para o controle de fungos nocivos, e, uso de uma ciclo-propano-carboxamida de fórmula i | |
| RU98114077A (ru) | Гетероциклические конденсированные бензоилгуанидины, их получение и их применение в качестве ингибиторов клеточного na+/h+-антиносителя |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |