NO982755L - Kovalente lipid-fosfonokarboksylsyrederivater og deres anvendelse som antivirusmedikamenter - Google Patents

Kovalente lipid-fosfonokarboksylsyrederivater og deres anvendelse som antivirusmedikamenter

Info

Publication number
NO982755L
NO982755L NO982755A NO982755A NO982755L NO 982755 L NO982755 L NO 982755L NO 982755 A NO982755 A NO 982755A NO 982755 A NO982755 A NO 982755A NO 982755 L NO982755 L NO 982755L
Authority
NO
Norway
Prior art keywords
acid derivatives
antiviral drugs
phosphonocarboxylic acid
covalent lipid
covalent
Prior art date
Application number
NO982755A
Other languages
English (en)
Other versions
NO982755D0 (no
Inventor
Harald Zilch
Dieter Herrmann
Hans-Georg Opitz
Gerd Zimmermann
Edgar Voss
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NO982755D0 publication Critical patent/NO982755D0/no
Publication of NO982755L publication Critical patent/NO982755L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4062Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
    • C07F9/4065Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/12Mucolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO982755A 1995-12-15 1998-06-15 Kovalente lipid-fosfonokarboksylsyrederivater og deres anvendelse som antivirusmedikamenter NO982755L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19547022A DE19547022A1 (de) 1995-12-15 1995-12-15 Kovalente Lipid-Phosphonocarbonsäure-Konjugate, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
PCT/EP1996/005648 WO1997022368A2 (de) 1995-12-15 1996-12-16 Kovalente lipid-phosphonocarbonsäure-konjugate und ihre anwendung wie antivirale arzneimittel

Publications (2)

Publication Number Publication Date
NO982755D0 NO982755D0 (no) 1998-06-15
NO982755L true NO982755L (no) 1998-08-14

Family

ID=7780310

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982755A NO982755L (no) 1995-12-15 1998-06-15 Kovalente lipid-fosfonokarboksylsyrederivater og deres anvendelse som antivirusmedikamenter

Country Status (25)

Country Link
US (1) US5955452A (no)
EP (1) EP0869817B1 (no)
JP (1) JP2000505784A (no)
KR (1) KR20000064375A (no)
CN (1) CN1209069A (no)
AR (1) AR005065A1 (no)
AT (1) ATE219379T1 (no)
AU (1) AU714922B2 (no)
BR (1) BR9612137A (no)
CA (1) CA2240365A1 (no)
CZ (1) CZ292531B6 (no)
DE (2) DE19547022A1 (no)
ES (1) ES2179222T3 (no)
HU (1) HUP0001524A3 (no)
IL (1) IL124789A (no)
MX (1) MX9804752A (no)
NO (1) NO982755L (no)
NZ (1) NZ325260A (no)
PL (1) PL185115B1 (no)
RU (1) RU2178418C2 (no)
SK (1) SK282035B6 (no)
TR (1) TR199801083T2 (no)
TW (1) TW409128B (no)
WO (1) WO1997022368A2 (no)
ZA (1) ZA9610511B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW343975B (en) * 1995-12-15 1998-11-01 Boehringer Mannheim Gmbh New phospholipid derivatives of phosphonocarboxylic acids, the production thereof as well as their use as antiviral pharmaceutical agents
US6818057B2 (en) 1999-03-02 2004-11-16 Construction Research & Technology Gmbh Retarder for calcium sulfoaluminate cements
US20040172288A1 (en) * 2003-02-27 2004-09-02 Korn Lawrence D. Method for disseminating medical alert information
JP5752599B2 (ja) * 2008-11-06 2015-07-22 ヴァスキュラー バイオジェニックス リミテッド 酸化脂質化合物およびその使用
EP2876094A1 (en) 2014-04-03 2015-05-27 Basf Se Cement and calcium sulphate based binder composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150125A (en) * 1977-09-30 1979-04-17 Abbott Laboratories Triglyceride ester of phosphonoacetic acid having antiviral activity
US5194654A (en) * 1989-11-22 1993-03-16 Vical, Inc. Lipid derivatives of phosphonoacids for liposomal incorporation and method of use
DE4026265A1 (de) * 1990-08-20 1992-02-27 Boehringer Mannheim Gmbh Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
TW343975B (en) * 1995-12-15 1998-11-01 Boehringer Mannheim Gmbh New phospholipid derivatives of phosphonocarboxylic acids, the production thereof as well as their use as antiviral pharmaceutical agents

Also Published As

Publication number Publication date
ATE219379T1 (de) 2002-07-15
PL185115B1 (pl) 2003-02-28
ES2179222T3 (es) 2003-01-16
HUP0001524A2 (hu) 2001-05-28
CA2240365A1 (en) 1997-06-26
CZ292531B6 (cs) 2003-10-15
MX9804752A (es) 1998-10-31
CZ180998A3 (cs) 1998-09-16
AR005065A1 (es) 1999-04-07
EP0869817B1 (de) 2002-06-19
AU714922B2 (en) 2000-01-13
WO1997022368A2 (de) 1997-06-26
CN1209069A (zh) 1999-02-24
PL327138A1 (en) 1998-11-23
NZ325260A (en) 1999-11-29
TW409128B (en) 2000-10-21
SK75598A3 (en) 1999-04-13
ZA9610511B (en) 1998-06-15
DE19547022A1 (de) 1997-06-19
WO1997022368A3 (de) 1997-10-23
TR199801083T2 (xx) 1998-10-21
BR9612137A (pt) 1999-07-13
US5955452A (en) 1999-09-21
IL124789A (en) 2002-03-10
NO982755D0 (no) 1998-06-15
DE59609377D1 (de) 2002-07-25
SK282035B6 (sk) 2001-10-08
RU2178418C2 (ru) 2002-01-20
HUP0001524A3 (en) 2001-05-28
EP0869817A2 (de) 1998-10-14
AU1373197A (en) 1997-07-14
IL124789A0 (en) 1999-01-26
JP2000505784A (ja) 2000-05-16
KR20000064375A (ko) 2000-11-06

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