NO981799L - Farmas÷ytiske blandinger av levo-enantiomere av medetomidinderivater og deres anvendelse - Google Patents
Farmas÷ytiske blandinger av levo-enantiomere av medetomidinderivater og deres anvendelseInfo
- Publication number
- NO981799L NO981799L NO981799A NO981799A NO981799L NO 981799 L NO981799 L NO 981799L NO 981799 A NO981799 A NO 981799A NO 981799 A NO981799 A NO 981799A NO 981799 L NO981799 L NO 981799L
- Authority
- NO
- Norway
- Prior art keywords
- pct
- receptors
- adrenergic alpha
- medetomidine
- levo
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Resins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9521680.0A GB9521680D0 (en) | 1995-10-23 | 1995-10-23 | New use of imidazole derivatives |
PCT/FI1996/000560 WO1997015302A1 (en) | 1995-10-23 | 1996-10-23 | Pharmaceutical compositions of levo-enantiomers of medetomidine derivatives and their use |
Publications (2)
Publication Number | Publication Date |
---|---|
NO981799L true NO981799L (no) | 1998-04-22 |
NO981799D0 NO981799D0 (no) | 1998-04-22 |
Family
ID=10782758
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO981799A NO981799D0 (no) | 1995-10-23 | 1998-04-22 | Farmas÷ytiske blandinger av levo-enantiomere av medetomidinderivater og deres anvendelse |
Country Status (22)
Country | Link |
---|---|
US (1) | US5994384A (no) |
EP (1) | EP0858338B1 (no) |
JP (1) | JP2000503298A (no) |
KR (1) | KR19990067008A (no) |
CN (1) | CN1200035A (no) |
AT (1) | ATE218340T1 (no) |
AU (1) | AU707728B2 (no) |
BG (1) | BG102396A (no) |
CA (1) | CA2232336A1 (no) |
CZ (1) | CZ120498A3 (no) |
DE (1) | DE69621633T2 (no) |
EE (1) | EE9800131A (no) |
ES (1) | ES2178717T3 (no) |
GB (1) | GB9521680D0 (no) |
HU (1) | HUP9900027A3 (no) |
IL (1) | IL123999A (no) |
NO (1) | NO981799D0 (no) |
NZ (1) | NZ320289A (no) |
PL (1) | PL326562A1 (no) |
RU (1) | RU2193404C2 (no) |
SK (1) | SK48698A3 (no) |
WO (1) | WO1997015302A1 (no) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6329369B1 (en) | 1997-12-04 | 2001-12-11 | Allergan Sales, Inc. | Methods of treating pain and other conditions |
US6841684B2 (en) | 1997-12-04 | 2005-01-11 | Allergan, Inc. | Imidiazoles having reduced side effects |
AU5331200A (en) * | 1999-06-11 | 2001-01-02 | Ohio State University Research Foundation, The | Methods and compositions for treating raynaud's phenomenon and scleroderma |
US6444681B1 (en) | 2000-06-09 | 2002-09-03 | The Ohio State University Research Foundation | Methods and compositions for treating Raynaud's Phenomenon and scleroderma |
NZ527142A (en) * | 2003-07-23 | 2006-03-31 | Douglas Pharmaceuticals Ltd | A stable suspension formulation |
JP2009524616A (ja) | 2006-01-27 | 2009-07-02 | エフ.ホフマン−ラ ロシュ アーゲー | Cns疾患のための4−イミダゾール誘導体の使用 |
CN101671305A (zh) * | 2009-09-29 | 2010-03-17 | 北京华禧联合科技发展有限公司 | 一种拆分美托咪定的左旋及右旋对映体的方法 |
EP2782569A1 (en) * | 2011-11-21 | 2014-10-01 | Allergan, Inc. | Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3h-imidazole derivatives for treating retinal diseases |
KR101831536B1 (ko) | 2013-07-24 | 2018-04-04 | 아이-테크 에이비 | 표면의 해양 바이오파울링 억제제로서 거울상 이성질체 레보메데토미딘의 용도 |
CN105764496B (zh) | 2013-10-07 | 2020-09-25 | 帝国制药美国公司 | 用于经皮递送非镇静量的右旋美托咪啶的方法和组合物 |
EP3054935B1 (en) | 2013-10-07 | 2020-12-09 | Teikoku Pharma USA, Inc. | Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions |
CA2924231C (en) | 2013-10-07 | 2018-04-03 | Teikoku Pharma Usa, Inc. | Dexmedetomidine transdermal delivery devices and methods for using the same |
US20150098983A1 (en) * | 2013-10-07 | 2015-04-09 | Teikoku Pharma Usa, Inc. | Methods and Compositions for Treating Withdrawal Syndromes Using Non-Sedative Dexmedetomidine Transdermal Compositions |
CN106442765A (zh) * | 2016-08-31 | 2017-02-22 | 辰欣药业股份有限公司 | 一种盐酸右美托咪定粗品中异构体的检测方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2101114B (en) * | 1981-07-10 | 1985-05-22 | Farmos Group Ltd | Substituted imidazole derivatives and their preparation and use |
GB8626287D0 (en) * | 1986-11-04 | 1986-12-03 | Ucb Sa | Substituted 1h-imidazoles |
GB2206880B (en) * | 1987-07-16 | 1991-04-24 | Farmos Oy | Optical isomers of an imidazole derivative |
GB8810067D0 (en) * | 1988-04-28 | 1988-06-02 | Ucb Sa | Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides |
US5124157A (en) * | 1989-08-18 | 1992-06-23 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
CA2089261A1 (en) * | 1990-08-30 | 1992-03-01 | John F.W. Keana | Substituted amidines having high binding to the sigma receptor and the use thereof |
GB9111732D0 (en) * | 1991-05-31 | 1991-07-24 | Orion Yhtymae Oy | The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs |
GB9310965D0 (en) * | 1993-05-27 | 1993-07-14 | Ucb Sa | 2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides |
-
1995
- 1995-10-23 GB GBGB9521680.0A patent/GB9521680D0/en active Pending
-
1996
- 1996-10-23 HU HU9900027A patent/HUP9900027A3/hu unknown
- 1996-10-23 ES ES96934847T patent/ES2178717T3/es not_active Expired - Lifetime
- 1996-10-23 RU RU98109949/14A patent/RU2193404C2/ru not_active IP Right Cessation
- 1996-10-23 AT AT96934847T patent/ATE218340T1/de not_active IP Right Cessation
- 1996-10-23 DE DE69621633T patent/DE69621633T2/de not_active Expired - Fee Related
- 1996-10-23 CN CN96197793A patent/CN1200035A/zh active Pending
- 1996-10-23 SK SK486-98A patent/SK48698A3/sk unknown
- 1996-10-23 US US09/043,107 patent/US5994384A/en not_active Expired - Fee Related
- 1996-10-23 AU AU73019/96A patent/AU707728B2/en not_active Ceased
- 1996-10-23 PL PL96326562A patent/PL326562A1/xx unknown
- 1996-10-23 CA CA002232336A patent/CA2232336A1/en not_active Abandoned
- 1996-10-23 NZ NZ320289A patent/NZ320289A/xx unknown
- 1996-10-23 CZ CZ981204A patent/CZ120498A3/cs unknown
- 1996-10-23 JP JP9516319A patent/JP2000503298A/ja active Pending
- 1996-10-23 WO PCT/FI1996/000560 patent/WO1997015302A1/en not_active Application Discontinuation
- 1996-10-23 EE EE9800131A patent/EE9800131A/xx unknown
- 1996-10-23 EP EP96934847A patent/EP0858338B1/en not_active Expired - Lifetime
- 1996-10-23 IL IL12399996A patent/IL123999A/en not_active IP Right Cessation
- 1996-10-23 KR KR1019980702944A patent/KR19990067008A/ko not_active Application Discontinuation
-
1998
- 1998-04-21 BG BG102396A patent/BG102396A/xx unknown
- 1998-04-22 NO NO981799A patent/NO981799D0/no unknown
Also Published As
Publication number | Publication date |
---|---|
NZ320289A (en) | 1999-08-30 |
IL123999A (en) | 2002-09-12 |
BG102396A (en) | 1999-01-29 |
ES2178717T3 (es) | 2003-01-01 |
CA2232336A1 (en) | 1997-05-01 |
HUP9900027A3 (en) | 1999-11-29 |
JP2000503298A (ja) | 2000-03-21 |
EE9800131A (et) | 1998-10-15 |
GB9521680D0 (en) | 1996-01-03 |
DE69621633T2 (de) | 2003-02-06 |
DE69621633D1 (de) | 2002-07-11 |
EP0858338B1 (en) | 2002-06-05 |
AU707728B2 (en) | 1999-07-15 |
CZ120498A3 (cs) | 1998-09-16 |
SK48698A3 (en) | 1999-03-12 |
RU2193404C2 (ru) | 2002-11-27 |
KR19990067008A (ko) | 1999-08-16 |
AU7301996A (en) | 1997-05-15 |
ATE218340T1 (de) | 2002-06-15 |
CN1200035A (zh) | 1998-11-25 |
NO981799D0 (no) | 1998-04-22 |
EP0858338A1 (en) | 1998-08-19 |
WO1997015302A1 (en) | 1997-05-01 |
US5994384A (en) | 1999-11-30 |
PL326562A1 (en) | 1998-09-28 |
HUP9900027A2 (hu) | 1999-04-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO981799L (no) | Farmas÷ytiske blandinger av levo-enantiomere av medetomidinderivater og deres anvendelse | |
AU2002234134A1 (en) | 3-substituted oxindole beta 3 agonists | |
IL109337A0 (en) | Indole derivatives for use in migraine | |
AU2506197A (en) | Use of agonists of the peroxisome proliferator activated receptor alpha for treating obesity | |
NO952229L (no) | Anvendelse av karbamazepin og okskarbazepin ved behandling av neurologiske lesjoner relatert til traumatiske skader | |
FI935960A (fi) | Foerfarande foer framstaellning av papper | |
ES2121193T3 (es) | Derivados de bencimidazoles. | |
AU2002347982A1 (en) | 3-SUBSTITUTED OXINDOLE Beta3 AGONISTS | |
ES2110225T3 (es) | Derivados antisicoticos de indazol. | |
NO982778D0 (no) | Morfinderivater med smertestillende virkning | |
ATE197453T1 (de) | Imidazol-, triazol- und tetrazolderivate | |
Drobnik et al. | The opposite effect of morning or afternoon application of melatonin on collagen accumulation in the sponge-induced granuloma | |
Trapp et al. | Direct interaction of Na‐azide with the KATP channel | |
Altenburg et al. | Tizanidine Protects Mice against Convulsions Induced by Lidocaine: Involvement of α2‐Adrenoceptors | |
AU3267097A (en) | Methanesulphonate salt of an arylpiperazine derived from tryptamine and its solvates for pharmaceutical use | |
Kitamura et al. | Effects of nifedipine and Bay K 8644 on contractile activities in single skeletal muscle fibers of the frog | |
NO981222L (no) | Ny kombinasjon av en <beta>-reseptorblokker og et opioid | |
Goldfine et al. | S-4: Insulin receptor inhibitors as a cause of insulin resistance | |
DE69400908D1 (de) | Verwendung von riluzol zum schutz gegen strahlenschäden |