NO980594D0 - Fremgangsmåte for rensingen av et intermediat i fremstillingen av iopamidol - Google Patents

Fremgangsmåte for rensingen av et intermediat i fremstillingen av iopamidol

Info

Publication number
NO980594D0
NO980594D0 NO980594A NO980594A NO980594D0 NO 980594 D0 NO980594 D0 NO 980594D0 NO 980594 A NO980594 A NO 980594A NO 980594 A NO980594 A NO 980594A NO 980594 D0 NO980594 D0 NO 980594D0
Authority
NO
Norway
Prior art keywords
purification
iopamidol
preparation
triiodo
oxopropyl
Prior art date
Application number
NO980594A
Other languages
English (en)
Other versions
NO980594L (no
NO324342B1 (no
Inventor
Nicola Desantis
Original Assignee
Fructamine Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fructamine Spa filed Critical Fructamine Spa
Publication of NO980594D0 publication Critical patent/NO980594D0/no
Publication of NO980594L publication Critical patent/NO980594L/no
Publication of NO324342B1 publication Critical patent/NO324342B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Removal Of Specific Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Carbon And Carbon Compounds (AREA)
NO19980594A 1996-06-13 1998-02-11 Fremgangsmate ved fremstilling av (S)-N, N'-bis((2-hydroksy-1-(hydroksymetyl)etyl)-5-((2-hydroksy-1-oksopropyl)amino)-2,4,6-trijod-1,3-benzendikarboksamid NO324342B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI001204A IT1288114B1 (it) 1996-06-13 1996-06-13 Processo per la purificazione di un intermedio
PCT/EP1997/003021 WO1997047590A2 (en) 1996-06-13 1997-06-11 Process for the purification of an intermediate in the preparation of iopamidol

Publications (3)

Publication Number Publication Date
NO980594D0 true NO980594D0 (no) 1998-02-11
NO980594L NO980594L (no) 1998-04-07
NO324342B1 NO324342B1 (no) 2007-09-24

Family

ID=11374420

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19980594A NO324342B1 (no) 1996-06-13 1998-02-11 Fremgangsmate ved fremstilling av (S)-N, N'-bis((2-hydroksy-1-(hydroksymetyl)etyl)-5-((2-hydroksy-1-oksopropyl)amino)-2,4,6-trijod-1,3-benzendikarboksamid

Country Status (17)

Country Link
US (1) US5849953A (no)
EP (1) EP0851854B1 (no)
JP (1) JP4018751B2 (no)
CN (1) CN1089335C (no)
AT (1) ATE210630T1 (no)
AU (1) AU3094597A (no)
CZ (1) CZ293956B6 (no)
DE (1) DE69709044T2 (no)
ES (1) ES2165610T3 (no)
HU (1) HU227980B1 (no)
IL (1) IL123259A (no)
IN (1) IN182809B (no)
IT (1) IT1288114B1 (no)
NO (1) NO324342B1 (no)
PT (1) PT851854E (no)
WO (1) WO1997047590A2 (no)
ZA (1) ZA975203B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1299202B1 (it) * 1998-05-08 2000-02-29 Dibra Spa Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo
IT1302200B1 (it) 1998-09-11 2000-07-31 Dibra Spa PROCESSO PER LA PREPARAZIONE DELLA S-N,N'-BIS°2-IDROSSI-1-(IDROSSIMETIL)ETILé-5-°(2-IDROSSI-1-
DE102007053531B4 (de) * 2007-11-09 2010-10-21 Hs Genion Gmbh Rolloeinrichtung
EP2230227A1 (en) 2009-03-20 2010-09-22 Bracco Imaging S.p.A Process for the preparation of triiodinated carboxylic aromatic derivatives
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
IT1403988B1 (it) * 2010-07-15 2013-11-08 Bracco Imaging Spa Processo per la preparazione di agenti di contrasto.
AU2013357598B2 (en) 2012-12-11 2017-12-21 Bracco Imaging Spa Continuous process for the preparation of (S)-2-acetyloxypropionic acid chloride
EP3369724B1 (en) 2013-11-05 2021-01-06 Bracco Imaging SPA Process for the preparation of iopamidol
KR102358241B1 (ko) 2014-06-10 2022-02-04 브라코 이미징 에스.피.에이. (s)-2-아세틸옥시프로피온산 및 그것의 유도체의 제조 방법
PT108524B (pt) * 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
EP3548461B1 (en) 2016-12-05 2021-02-03 Bracco Imaging SpA Mechanochemical synthesis of radiographic agents intermediates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3324107A (en) * 1964-03-27 1967-06-06 Du Pont Dialkylamide purification
US3576870A (en) * 1967-07-05 1971-04-27 Du Pont Process for purifying n,n-dimethylacetamide
CH608189A5 (no) * 1974-12-13 1978-12-29 Savac Ag
CH616403A5 (en) * 1975-10-29 1980-03-31 Bracco Ind Chimica Spa Process for the preparation of 2,4,6-triodoisophthalamides which are readily soluble in water.
IT1193211B (it) * 1979-08-09 1988-06-15 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
GB2088850B (en) * 1980-12-09 1983-09-28 Coal Industry Patents Ltd Treatment of n-methyl pyrrolidone
IT1256162B (it) * 1992-10-27 1995-11-29 Zambon Spa Processo per la preparazione di un intermedio della sintesi organica

Also Published As

Publication number Publication date
CZ293956B6 (cs) 2004-08-18
HUP9901631A2 (hu) 1999-08-30
HU227980B1 (en) 2012-07-30
ITMI961204A0 (no) 1996-06-13
ES2165610T3 (es) 2002-03-16
IT1288114B1 (it) 1998-09-10
IL123259A (en) 2000-07-16
JPH11510827A (ja) 1999-09-21
JP4018751B2 (ja) 2007-12-05
DE69709044D1 (de) 2002-01-24
IL123259A0 (en) 1998-09-24
HUP9901631A3 (en) 2001-02-28
ITMI961204A1 (it) 1997-12-13
CN1195338A (zh) 1998-10-07
EP0851854B1 (en) 2001-12-12
NO980594L (no) 1998-04-07
IN182809B (no) 1999-07-24
CN1089335C (zh) 2002-08-21
PT851854E (pt) 2002-06-28
DE69709044T2 (de) 2002-08-22
WO1997047590A3 (en) 1998-04-02
ATE210630T1 (de) 2001-12-15
WO1997047590A2 (en) 1997-12-18
US5849953A (en) 1998-12-15
AU3094597A (en) 1998-01-07
NO324342B1 (no) 2007-09-24
EP0851854A2 (en) 1998-07-08
CZ39998A3 (cs) 1998-07-15
ZA975203B (en) 1998-01-20

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