NO980145D0 - Polyucykliske alkaloid-derivater som NMDA-reseptor-antagonister - Google Patents

Polyucykliske alkaloid-derivater som NMDA-reseptor-antagonister

Info

Publication number
NO980145D0
NO980145D0 NO980145A NO980145A NO980145D0 NO 980145 D0 NO980145 D0 NO 980145D0 NO 980145 A NO980145 A NO 980145A NO 980145 A NO980145 A NO 980145A NO 980145 D0 NO980145 D0 NO 980145D0
Authority
NO
Norway
Prior art keywords
alkyl
pct
independently
polyucyclic
receptor antagonists
Prior art date
Application number
NO980145A
Other languages
English (en)
Other versions
NO980145L (no
Inventor
John Dimaio
Dilip M Dixit
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of NO980145L publication Critical patent/NO980145L/no
Publication of NO980145D0 publication Critical patent/NO980145D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/44Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D225/00Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/08Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/16Eight-membered rings
    • C07D313/20Eight-membered rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D337/00Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/16Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO980145A 1995-07-14 1998-01-13 Polyucykliske alkaloid-derivater som NMDA-reseptor-antagonister NO980145D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514448.1A GB9514448D0 (en) 1995-07-14 1995-07-14 Novel heterocyclic NMDA-receptor antagonists
PCT/CA1996/000468 WO1997003979A1 (en) 1995-07-14 1996-07-12 Polycyclic alcaloid-derivatives as nmda-receptor antagonists

Publications (2)

Publication Number Publication Date
NO980145L NO980145L (no) 1998-01-13
NO980145D0 true NO980145D0 (no) 1998-01-13

Family

ID=10777682

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980145A NO980145D0 (no) 1995-07-14 1998-01-13 Polyucykliske alkaloid-derivater som NMDA-reseptor-antagonister

Country Status (12)

Country Link
US (1) US5990104A (no)
EP (1) EP0840731B1 (no)
JP (1) JPH11509533A (no)
CN (1) CN1195344A (no)
AT (1) ATE206616T1 (no)
AU (1) AU696502B2 (no)
CA (1) CA2223644A1 (no)
DE (1) DE69615845T2 (no)
ES (1) ES2164901T3 (no)
GB (1) GB9514448D0 (no)
NO (1) NO980145D0 (no)
WO (1) WO1997003979A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003528148A (ja) * 2000-03-28 2003-09-24 デロレンゾ、ロバート・ジェイ 損傷に際して神経細胞中に形成される新規カルシウム損傷電流の阻害は神経細胞死を抑制する
AUPR215700A0 (en) * 2000-12-19 2001-01-25 Fujisawa Pharmaceutical Co., Ltd. Carboxylic acid compound having cyclopropane ring
US20060142186A1 (en) * 2004-12-23 2006-06-29 Voyager Pharmaceutical Corporation Leuprolide acetate and acetylcholinesterase inhibitors or NMDA receptor antagonists for the treatment of alzheimer's disease
US20220117913A1 (en) * 2019-02-02 2022-04-21 Yangtze River Pharmaceutical Group Co., Ltd. Dezocine derivative and medical use thereof
CN112137996B (zh) * 2020-10-23 2023-08-25 湖南农业大学 一种预防钩吻中毒的药物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3836670A (en) * 1971-11-19 1974-09-17 American Home Prod Benzobicycloalkane amines for inducing analgesia
US4957909A (en) * 1989-05-04 1990-09-18 American Home Products Corporation Benzobicycloalkane derivatives as anticonvulsant neuroprotective agents

Also Published As

Publication number Publication date
NO980145L (no) 1998-01-13
EP0840731B1 (en) 2001-10-10
AU696502B2 (en) 1998-09-10
CN1195344A (zh) 1998-10-07
ES2164901T3 (es) 2002-03-01
ATE206616T1 (de) 2001-10-15
DE69615845D1 (de) 2001-11-15
EP0840731A1 (en) 1998-05-13
US5990104A (en) 1999-11-23
WO1997003979A1 (en) 1997-02-06
DE69615845T2 (de) 2002-06-20
AU6350296A (en) 1997-02-18
GB9514448D0 (en) 1995-09-13
CA2223644A1 (en) 1997-02-06
JPH11509533A (ja) 1999-08-24

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Legal Events

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