NO973017L - Nye trienoiske retinoid forbindelser og fremgangsmåter - Google Patents
Nye trienoiske retinoid forbindelser og fremgangsmåterInfo
- Publication number
- NO973017L NO973017L NO973017A NO973017A NO973017L NO 973017 L NO973017 L NO 973017L NO 973017 A NO973017 A NO 973017A NO 973017 A NO973017 A NO 973017A NO 973017 L NO973017 L NO 973017L
- Authority
- NO
- Norway
- Prior art keywords
- methods
- trienoic
- new
- retinoid compounds
- retinoid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
- C07C311/49—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/42—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/48—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C07C69/618—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36661394A | 1994-12-30 | 1994-12-30 | |
US08/480,127 US5721103A (en) | 1994-12-30 | 1995-06-07 | Trienoic retinoid compounds and methods |
US08/481,877 US6083977A (en) | 1994-12-30 | 1995-06-07 | Trienoic retinoid compounds and methods |
PCT/US1995/016695 WO1996020913A1 (en) | 1994-12-30 | 1995-12-21 | Novel trienoic retinoid compounds and methods |
Publications (3)
Publication Number | Publication Date |
---|---|
NO973017D0 NO973017D0 (no) | 1997-06-27 |
NO973017L true NO973017L (no) | 1997-08-28 |
NO310408B1 NO310408B1 (no) | 2001-07-02 |
Family
ID=27408763
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19973017A NO310408B1 (no) | 1994-12-30 | 1997-06-27 | Nye trienoiske retinoidforbindelser, fremgangsmåter og anvendelse |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0800503B1 (no) |
JP (1) | JP4001913B2 (no) |
CN (1) | CN1121374C (no) |
AT (1) | ATE192731T1 (no) |
AU (1) | AU712187B2 (no) |
CA (1) | CA2208981C (no) |
DE (1) | DE69516903T2 (no) |
DK (1) | DK0800503T3 (no) |
ES (1) | ES2148593T3 (no) |
GR (1) | GR3033676T3 (no) |
MX (1) | MX9704878A (no) |
NO (1) | NO310408B1 (no) |
PT (1) | PT800503E (no) |
WO (1) | WO1996020913A1 (no) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7115728B1 (en) | 1995-01-30 | 2006-10-03 | Ligand Pharmaceutical Incorporated | Human peroxisome proliferator activated receptor γ |
AU7074496A (en) | 1995-09-18 | 1997-04-09 | Ligand Pharmaceuticals Incorporated | Ppar gamma antagonists for treating obesity |
JPH10158192A (ja) * | 1996-10-03 | 1998-06-16 | Eisai Co Ltd | 移植片対宿主疾患(gvhd)の治療および臓器移植時の移植片拒絶反応抑制のための医薬組成物 |
EP1093362A1 (en) | 1998-06-12 | 2001-04-25 | Ligand Pharmaceuticals Incorporated | Treatment of anti-estrogen resistant breast cancer using rxr modulators |
AU9556298A (en) * | 1998-11-03 | 2000-05-22 | Ligand Pharmaceuticals Incorporated | Trienoic retinoid compounds as retinoic acid receptor antagonists |
US6326397B1 (en) | 1998-11-10 | 2001-12-04 | Hoffman-La Roche Inc. | Retinoid antagonists and use thereof |
ATE260242T1 (de) | 1998-12-17 | 2004-03-15 | Hoffmann La Roche | 7-aryl-6(z)heptatriensäure retinamide als apoptose induzierende verbindungen und deren verwendung als antikrebsmittel |
FR2787789B1 (fr) | 1998-12-29 | 2002-06-14 | Lipha | Benzopyranes et benzoxepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparations |
EP1161410B1 (en) * | 1999-03-08 | 2004-05-12 | Basilea Pharmaceutica AG | Retinoid antagonists and use thereof |
KR100588284B1 (ko) | 1999-04-07 | 2006-06-09 | 상꾜 가부시키가이샤 | 아민 유도체 화합물 |
TR200200507T2 (tr) | 1999-08-27 | 2002-10-21 | Ligand Pharmaceuticals Inc | Androjen reseptörü modülatör bileşikleri ve metotları |
US6566372B1 (en) | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
WO2001016133A2 (en) | 1999-08-27 | 2001-03-08 | Ligand Pharmaceuticals Incorporated | 8-substituted-6-trifluoromethyl-9-pyrido[3,2-g]quinoline compounds as androgen receptor modulators |
WO2001019770A2 (en) * | 1999-09-14 | 2001-03-22 | Ligand Pharmaceuticals Incorporated | Rxr modulators with improved pharmacologic profile |
DE122008000018I1 (de) | 2000-01-21 | 2008-08-14 | Novartis Pharma Ag | Zusammensetzungen bestehend aus Dipeptidylpeptidase-IV Inhibitoren und Antidiabetica |
WO2003051382A1 (fr) * | 2001-12-14 | 2003-06-26 | Sundory Co., Ltd. | Procédé d'induction d'apoptose et compositions pour cette dernière |
JP5877466B2 (ja) * | 2012-02-29 | 2016-03-08 | 国立大学法人 岡山大学 | テルペノイド由来レチノイド化合物 |
KR101556439B1 (ko) | 2013-07-01 | 2015-10-15 | 서울대학교산학협력단 | 미토콘드리아 역행성 신호 경로와 관련된 RXRα의 기능 및 용도 |
US20160263189A1 (en) | 2013-10-23 | 2016-09-15 | Acadia Pharmaceuticals Inc. | Treatment of a neurodegenerative disease or disorder |
CN103759895B (zh) * | 2013-11-26 | 2016-03-23 | 四川蓝讯宝迩电子科技有限公司 | 气体减压阀进气端的装配测试基台 |
JP2022513114A (ja) | 2018-11-26 | 2022-02-07 | デナリ セラピューティクス インコーポレイテッド | 脂質代謝調節不全の治療方法 |
CN118005594A (zh) * | 2023-05-24 | 2024-05-10 | 内蒙古大学 | 3-羟基苯并二氢吡喃衍生物的合成及其抗肿瘤活性 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3882157A (en) * | 1972-07-27 | 1975-05-06 | Zoecon Corp | Thiolesters of phenylheptadienoic acids |
US3845089A (en) * | 1972-07-27 | 1974-10-29 | Zoecon Corp | Phenylheptadienoates |
LU77254A1 (no) * | 1977-05-04 | 1979-01-18 | ||
FR2719041B1 (fr) * | 1994-04-26 | 1996-05-31 | Cird Galderma | Nouveaux composés polyéniques, compositions pharmaceutiques et cosmétiques les contenant et utilisations. |
-
1995
- 1995-12-21 AT AT95944360T patent/ATE192731T1/de not_active IP Right Cessation
- 1995-12-21 EP EP95944360A patent/EP0800503B1/en not_active Expired - Lifetime
- 1995-12-21 DE DE69516903T patent/DE69516903T2/de not_active Expired - Fee Related
- 1995-12-21 MX MX9704878A patent/MX9704878A/es not_active IP Right Cessation
- 1995-12-21 WO PCT/US1995/016695 patent/WO1996020913A1/en active IP Right Grant
- 1995-12-21 JP JP52108896A patent/JP4001913B2/ja not_active Expired - Fee Related
- 1995-12-21 DK DK95944360T patent/DK0800503T3/da active
- 1995-12-21 CA CA002208981A patent/CA2208981C/en not_active Expired - Fee Related
- 1995-12-21 CN CN95197736A patent/CN1121374C/zh not_active Expired - Fee Related
- 1995-12-21 PT PT95944360T patent/PT800503E/pt unknown
- 1995-12-21 ES ES95944360T patent/ES2148593T3/es not_active Expired - Lifetime
- 1995-12-21 AU AU46430/96A patent/AU712187B2/en not_active Ceased
-
1997
- 1997-06-27 NO NO19973017A patent/NO310408B1/no not_active IP Right Cessation
-
2000
- 2000-06-14 GR GR20000401363T patent/GR3033676T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2208981A1 (en) | 1996-07-11 |
CN1121374C (zh) | 2003-09-17 |
EP0800503B1 (en) | 2000-05-10 |
DE69516903D1 (de) | 2000-06-15 |
DK0800503T3 (da) | 2000-08-07 |
AU712187B2 (en) | 1999-10-28 |
EP0800503A1 (en) | 1997-10-15 |
CN1220656A (zh) | 1999-06-23 |
NO973017D0 (no) | 1997-06-27 |
PT800503E (pt) | 2000-11-30 |
CA2208981C (en) | 2008-08-26 |
ES2148593T3 (es) | 2000-10-16 |
JPH10511948A (ja) | 1998-11-17 |
DE69516903T2 (de) | 2000-10-26 |
GR3033676T3 (en) | 2000-10-31 |
NO310408B1 (no) | 2001-07-02 |
WO1996020913A1 (en) | 1996-07-11 |
JP4001913B2 (ja) | 2007-10-31 |
MX9704878A (es) | 1997-11-29 |
AU4643096A (en) | 1996-07-24 |
ATE192731T1 (de) | 2000-05-15 |
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Legal Events
Date | Code | Title | Description |
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MM1K | Lapsed by not paying the annual fees |