NO970903L - Fusjonerte indol- og kinoksalderivater, deres fremstilling og anvendelse - Google Patents
Fusjonerte indol- og kinoksalderivater, deres fremstilling og anvendelseInfo
- Publication number
- NO970903L NO970903L NO970903A NO970903A NO970903L NO 970903 L NO970903 L NO 970903L NO 970903 A NO970903 A NO 970903A NO 970903 A NO970903 A NO 970903A NO 970903 L NO970903 L NO 970903L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- hydrogen
- amino
- alkoxy
- phenyl
- Prior art date
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 2
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- -1 hydroxy, amino Chemical group 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 125000001424 substituent group Chemical group 0.000 abstract 4
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical group O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK105494 | 1994-09-14 | ||
| PCT/EP1995/003594 WO1996008495A1 (en) | 1994-09-14 | 1995-09-12 | Fused indole and quinoxaline derivatives, their preparation and use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO970903D0 NO970903D0 (no) | 1997-02-27 |
| NO970903L true NO970903L (no) | 1997-05-07 |
| NO308851B1 NO308851B1 (no) | 2000-11-06 |
Family
ID=8100467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO970903A NO308851B1 (no) | 1994-09-14 | 1997-02-27 | Fusjonerte indol- og kinoksalderivater, farmasøytisk blanding og anvendelse av forbindelsen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5801174A (no) |
| EP (1) | EP0781285B1 (no) |
| JP (1) | JP3164372B2 (no) |
| AT (1) | ATE188701T1 (no) |
| AU (1) | AU686888B2 (no) |
| CA (1) | CA2199614C (no) |
| DE (1) | DE69514533T2 (no) |
| EE (1) | EE03772B1 (no) |
| FI (1) | FI112486B (no) |
| NO (1) | NO308851B1 (no) |
| NZ (1) | NZ293266A (no) |
| WO (1) | WO1996008495A1 (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
| FR2781482B1 (fr) * | 1998-07-27 | 2001-08-31 | Adir | Nouveaux derives de 8h-thieno-[2,3-b]pyrrolizine-8-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| DE60041399D1 (de) | 1999-05-19 | 2009-03-05 | Painceptor Pharma Corp | Hemmer der protonenabhängigen kationenkanäle und deren verwendung in der behandlung von ischemiebedingten erkrankungen |
| AU781067B2 (en) * | 2000-01-24 | 2005-05-05 | Neurosearch A/S | Isatine derivatives with neurotrophic activity |
| CN101346375B (zh) | 2005-11-23 | 2013-04-10 | 阿罗斯药物有限责任公司 | 调节门离子通道用组合物和方法 |
| WO2007070506A2 (en) | 2005-12-14 | 2007-06-21 | Amgen Inc. | Diaza heterocyclic sulfonamide derivatives and their uses |
| WO2007115409A1 (en) * | 2006-04-10 | 2007-10-18 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| US20090246134A1 (en) * | 2007-05-30 | 2009-10-01 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| CN104271749A (zh) | 2012-04-18 | 2015-01-07 | 雷蒙特亚特特拉维夫大学有限公司 | 用于递送核酸的脂化的糖胺聚糖颗粒 |
| WO2016114655A1 (en) * | 2015-01-12 | 2016-07-21 | Ry Pharma B.V. | Treating neuromuscular or neurologic disease through reducing gabaergic and/or glycinergic inhibitory neurotransmitter overstimulation |
| WO2017065602A1 (en) * | 2015-10-13 | 2017-04-20 | Ry Pharma B.V. | Treating neuromuscular or neurologic disease through reducing gabaergic and/or glycinergic inhibitory neurotransmitter overstimulation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9204914A (es) * | 1991-08-28 | 1993-07-01 | Frank Watjen | Nuevos derivados de isatinoxima, metodo para su preparacion y composicion farmaceutica que los comprende. |
| EP0664807B1 (en) * | 1992-10-13 | 1997-09-10 | Warner-Lambert Company | Quinoxalinedione derivatives as eaa antagonists |
-
1995
- 1995-09-12 JP JP50990896A patent/JP3164372B2/ja not_active Expired - Fee Related
- 1995-09-12 NZ NZ293266A patent/NZ293266A/en unknown
- 1995-09-12 DE DE69514533T patent/DE69514533T2/de not_active Expired - Lifetime
- 1995-09-12 WO PCT/EP1995/003594 patent/WO1996008495A1/en active IP Right Grant
- 1995-09-12 US US08/809,086 patent/US5801174A/en not_active Expired - Lifetime
- 1995-09-12 CA CA002199614A patent/CA2199614C/en not_active Expired - Fee Related
- 1995-09-12 AT AT95932730T patent/ATE188701T1/de not_active IP Right Cessation
- 1995-09-12 AU AU35665/95A patent/AU686888B2/en not_active Ceased
- 1995-09-12 EE EE9700051A patent/EE03772B1/xx not_active IP Right Cessation
- 1995-09-12 EP EP95932730A patent/EP0781285B1/en not_active Expired - Lifetime
-
1997
- 1997-02-25 FI FI970785A patent/FI112486B/fi active
- 1997-02-27 NO NO970903A patent/NO308851B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69514533D1 (de) | 2000-02-17 |
| JP3164372B2 (ja) | 2001-05-08 |
| AU686888B2 (en) | 1998-02-12 |
| CA2199614C (en) | 2000-02-22 |
| ATE188701T1 (de) | 2000-01-15 |
| US5801174A (en) | 1998-09-01 |
| EP0781285A1 (en) | 1997-07-02 |
| FI970785A0 (fi) | 1997-02-25 |
| AU3566595A (en) | 1996-03-29 |
| JPH09511525A (ja) | 1997-11-18 |
| FI970785A (fi) | 1997-03-13 |
| NO308851B1 (no) | 2000-11-06 |
| EP0781285B1 (en) | 2000-01-12 |
| NO970903D0 (no) | 1997-02-27 |
| CA2199614A1 (en) | 1996-03-21 |
| DE69514533T2 (de) | 2000-07-06 |
| FI112486B (fi) | 2003-12-15 |
| EE03772B1 (et) | 2002-06-17 |
| NZ293266A (en) | 1998-01-26 |
| WO1996008495A1 (en) | 1996-03-21 |
| EE9700051A (et) | 1997-08-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO970903D0 (no) | Fusjonerte indol- og kinoksalderivater, deres fremstilling og anvendelse | |
| NO20050666L (no) | 2,7-substituerte indoler og deres anvendelse som 5-HT6 modulatorer | |
| NO981609L (no) | Fusjonerte tropanderivater som inhiberer for neurotransmitteropptak | |
| NZ528997A (en) | Sulfonamides | |
| ATE161259T1 (de) | Ampa antagonisten und behandlungsmethode | |
| HUP9700595A1 (hu) | Fluor-alkil- és fluor-alkoxicsoporttal helyettesített heterociklikus bradikinin-antagonisták, eljárás ezek előállítására, valamint ezek alkalmazása | |
| DK0902684T3 (da) | Hexahydro-pyrido (4,3-B) indolderivater som antipsykotiske lægemidler | |
| NO970904L (no) | Indol-2,3-dion-3-oksim-derivater, deres fremstilling og anvendelse | |
| MXPA04005077A (es) | Derivados de benzotiazol. | |
| DE69510510D1 (de) | N-benzoylmethylsubstituierte paroxetinderivate | |
| DK0699197T3 (da) | 4-p-flourbenzoyl-1-piperidinyl-propoxy-chromen-4-on-derivater, deres fremstilling og deres anvendelse i behandlingen af psy | |
| DK0783504T3 (da) | (1,2,4)triazolo (4,3-a)guinoxalinon-derivater, deres fremstilling og anvendelse som antagonister af ampa-receptorer | |
| ES2161892T3 (es) | Derivados de indol como profarmacos de agonistas de los receptores afines a 5-ht1. |