NO970892L - Isoksazolderivater - Google Patents

Isoksazolderivater

Info

Publication number
NO970892L
NO970892L NO970892A NO970892A NO970892L NO 970892 L NO970892 L NO 970892L NO 970892 A NO970892 A NO 970892A NO 970892 A NO970892 A NO 970892A NO 970892 L NO970892 L NO 970892L
Authority
NO
Norway
Prior art keywords
group
ring
integer
alkylthio
amino
Prior art date
Application number
NO970892A
Other languages
English (en)
Other versions
NO970892D0 (no
NO308741B1 (no
Inventor
Koichi Kojima
Junichi Sakai
Yuichi Aizawa
Naozumi Samata
Masao Kozuka
Kenji Yoshimi
Isao Kaneko
Kazuro Koyama
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO970892D0 publication Critical patent/NO970892D0/no
Publication of NO970892L publication Critical patent/NO970892L/no
Publication of NO308741B1 publication Critical patent/NO308741B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO970892A 1994-08-30 1997-02-27 Isoksazolderivater, mellomprodukter, farmasøytiske preparater og anvendelse av derivatene NO308741B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP20536394 1994-08-30
JP15057195 1995-06-16
PCT/JP1995/001714 WO1996006837A1 (fr) 1994-08-30 1995-08-29 Isoxazoles

Publications (3)

Publication Number Publication Date
NO970892D0 NO970892D0 (no) 1997-02-27
NO970892L true NO970892L (no) 1997-04-29
NO308741B1 NO308741B1 (no) 2000-10-23

Family

ID=26480122

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970892A NO308741B1 (no) 1994-08-30 1997-02-27 Isoksazolderivater, mellomprodukter, farmasøytiske preparater og anvendelse av derivatene

Country Status (20)

Country Link
US (2) US5965591A (no)
EP (1) EP0779281B1 (no)
KR (1) KR970705549A (no)
CN (1) CN1098843C (no)
AT (1) ATE253057T1 (no)
AU (1) AU688102B2 (no)
CA (1) CA2198457A1 (no)
CZ (1) CZ290961B6 (no)
DE (1) DE69532039T2 (no)
DK (1) DK0779281T3 (no)
ES (1) ES2208690T3 (no)
FI (1) FI970864A (no)
HK (1) HK1018878A1 (no)
HU (1) HU221138B1 (no)
MX (1) MX9701630A (no)
NO (1) NO308741B1 (no)
NZ (1) NZ291508A (no)
PT (1) PT779281E (no)
RU (1) RU2140414C1 (no)
WO (1) WO1996006837A1 (no)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2198457A1 (en) * 1994-08-30 1996-03-07 Koichi Kojima Isoxazole derivatives
HUP9900400A3 (en) * 1996-02-27 2001-06-28 Sankyo Company Ltd Chuo Ku Isoxazole derivatives
US6339099B1 (en) * 1997-06-20 2002-01-15 Dupont Pharmaceuticals Company Guanidine mimics as factor Xa inhibitors
EP1135023A4 (en) * 1998-11-12 2003-03-05 Lilly Co Eli AMINOBENZISOXAZOLE COMPOUNDS AND LIBRARIES THEREOF
US6497928B1 (en) 1999-05-14 2002-12-24 Canon Kabushiki Kaisha Liquid crystal device, mesomorphic functional material and liquid crystal apparatus
US6638981B2 (en) 2001-08-17 2003-10-28 Epicept Corporation Topical compositions and methods for treating pain
RU2361862C2 (ru) * 2003-12-29 2009-07-20 Сепракор Инк. Пиррольные и пиразольные ингибиторы daao
ZA200605384B (en) * 2003-12-29 2007-10-31 Sepracor Inc Benzo[D]isoxazol-3-OL DAAO inhibitors
US20070197610A1 (en) * 2004-03-16 2007-08-23 Janssen Pharmaceutica N.V. Benzisoxazoles
CA2614282A1 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
US8053603B2 (en) * 2006-01-06 2011-11-08 Sunovion Pharmaceuticals Inc. Tetralone-based monoamine reuptake inhibitors
KR101294014B1 (ko) 2006-01-06 2013-08-09 선오비온 파마슈티컬스 인코포레이티드 모노아민 재흡수 저해제로서의 시클로알킬아민
PT2816024T (pt) 2006-03-31 2017-10-20 Sunovion Pharmaceuticals Inc Aminas quirais
US7884124B2 (en) * 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US7579370B2 (en) * 2006-06-30 2009-08-25 Sepracor Inc. Fused heterocycles
US20080082066A1 (en) * 2006-10-02 2008-04-03 Weyerhaeuser Co. Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks
ES2627221T3 (es) 2006-12-28 2017-07-27 Rigel Pharmaceuticals, Inc. Compuestos de heterocicloalquiloxibenzamida N-sustituidos y métodos de uso
US20090099248A1 (en) * 2007-01-18 2009-04-16 Sepracor Inc. Inhibitors of d-amino acid oxidase
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
RU2470011C2 (ru) 2007-05-31 2012-12-20 Сепракор Инк. Циклоалкиламины, содержащие в качестве заместителя фенил, как ингибиторы обратного захвата моноаминов
EP2254420A4 (en) 2008-02-20 2012-02-15 Targia Pharmaceuticals CNS PHARMACEUTICALS AND METHOD FOR THEIR USE
US20100120740A1 (en) * 2008-08-07 2010-05-13 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
US20110034434A1 (en) * 2009-08-07 2011-02-10 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
EP2533642A4 (en) 2010-02-11 2013-08-07 Univ Vanderbilt BENZISOXAZOLES AND AZABENZISOXAZOLES AS ALLOSTERIC POTENTIALIZERS OF METABOTROPIC GLUTAMATE RECEPTOR SUBType 4 (MGLUR4), COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTIONS
US9481677B2 (en) 2011-10-31 2016-11-01 Xenon Pharmaceuticals Inc. Biaryl ether sulfonamides and their use as therapeutic agents
CA2853439A1 (en) 2011-10-31 2013-05-10 Xenon Pharmaceuticals Inc. Benzenesulfonamide compounds and their use as therapeutic agents
SG11201408284VA (en) 2012-05-22 2015-02-27 Xenon Pharmaceuticals Inc N-substituted benzamides and their use in the treatment of pain
WO2014008458A2 (en) 2012-07-06 2014-01-09 Genentech, Inc. N-substituted benzamides and methods of use thereof
US9550775B2 (en) 2013-03-14 2017-01-24 Genentech, Inc. Substituted triazolopyridines and methods of use thereof
CN105492430B (zh) * 2013-03-15 2017-10-10 基因泰克公司 取代的苯并噁唑及其使用方法
BR112015023397A2 (pt) 2013-03-15 2017-07-18 Genentech Inc benzoxazois substituídos e métodos de uso dos mesmos
MX2016006936A (es) 2013-11-27 2016-10-05 Genentech Inc Benzamidas sustituidas y metodos para usarlas.
CN106715418A (zh) 2014-07-07 2017-05-24 基因泰克公司 治疗化合物及其使用方法
BR112017024853A2 (pt) 2015-05-22 2018-08-07 Genentech Inc composto, composição farmacêutica, método para tratar uma doença ou condição em um mamífero, para tratamento de prurido em um mamífero, para tratamento ou profilaxia e uso de um composto
JP2018526371A (ja) 2015-08-27 2018-09-13 ジェネンテック， インコーポレイテッド 治療化合物及びその使用方法
EP3380466A1 (en) 2015-11-25 2018-10-03 Genentech, Inc. Substituted benzamides useful as sodium channel blockers
JP2019513714A (ja) 2016-03-30 2019-05-30 ジェネンテック， インコーポレイテッド 置換ベンズアミド及びその使用方法
CN105801510A (zh) * 2016-04-08 2016-07-27 李勇 一种治疗抑郁症的药物组合物
AU2017347549A1 (en) 2016-10-17 2019-05-02 Genentech, Inc. Therapeutic compounds and methods of use thereof
CN110546148A (zh) 2017-03-24 2019-12-06 基因泰克公司 作为钠通道抑制剂的4-哌啶-n-(嘧啶-4-基)色满-7-磺酰胺衍生物
TW202000651A (zh) 2018-02-26 2020-01-01 美商建南德克公司 治療性組成物及其使用方法
US10947251B2 (en) 2018-03-30 2021-03-16 Genentech, Inc. Therapeutic compounds and methods of use thereof
CN114349690B (zh) * 2022-02-15 2023-04-25 甘肃皓天医药科技有限责任公司 一种多拉韦林中间体合成方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1265824A (no) * 1968-03-28 1972-03-08
US3812187A (en) * 1970-02-05 1974-05-21 Merck & Co Inc Hydrazides
SU539522A3 (ru) * 1970-02-05 1976-12-15 Мерк Энд Ко. Инк. (Фирма) Способ получени гидразин- -фенилпропионовой кислоты
JPS476302Y1 (no) * 1970-06-08 1972-03-04
US5321037A (en) * 1986-12-26 1994-06-14 Sankyo Company, Limited Isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants
IE62276B1 (en) * 1988-03-30 1995-01-25 Sankyo Co "New isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants"
US5116839A (en) * 1989-06-26 1992-05-26 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
US5352688A (en) * 1991-02-14 1994-10-04 The Mount Sinai School Of Medicine Of The City University Of New York Methods for the treatment of bradyphrenia in parkinson's disease
US5750542A (en) * 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
JPH0588630A (ja) * 1991-09-30 1993-04-09 Toshiba Lighting & Technol Corp 表示装置
EP0665226A1 (en) * 1992-10-28 1995-08-02 Toyama Chemical Co., Ltd. Novel 1,2-benzisoxazole derivative or salt thereof, and brain protective agent comprising the same
US5494908A (en) * 1992-11-23 1996-02-27 Hoechst-Roussel Pharmaceutical Incorporated Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds
CA2198457A1 (en) * 1994-08-30 1996-03-07 Koichi Kojima Isoxazole derivatives
CA2190708A1 (en) * 1995-12-08 1997-06-09 Johannes Aebi Aminoalkyl substituted benzo-heterocyclic compounds
JP5229734B2 (ja) * 2008-11-26 2013-07-03 住化エンビロサイエンス株式会社 木材保存組成物

Also Published As

Publication number Publication date
RU2140414C1 (ru) 1999-10-27
PT779281E (pt) 2004-02-27
CA2198457A1 (en) 1996-03-07
DE69532039T2 (de) 2004-07-08
ES2208690T3 (es) 2004-06-16
CZ59897A3 (en) 1997-07-16
DE69532039D1 (de) 2003-12-04
DK0779281T3 (da) 2004-03-08
NZ291508A (en) 1999-07-29
EP0779281A4 (en) 2000-07-26
ATE253057T1 (de) 2003-11-15
CN1162957A (zh) 1997-10-22
AU688102B2 (en) 1998-03-05
US6096771A (en) 2000-08-01
HU221138B1 (en) 2002-08-28
FI970864A0 (fi) 1997-02-28
NO970892D0 (no) 1997-02-27
CZ290961B6 (cs) 2002-11-13
HK1018878A1 (en) 2000-01-07
HUT77225A (hu) 1998-03-02
AU3266095A (en) 1996-03-22
FI970864A (fi) 1997-04-24
NO308741B1 (no) 2000-10-23
WO1996006837A1 (fr) 1996-03-07
US5965591A (en) 1999-10-12
EP0779281B1 (en) 2003-10-29
EP0779281A1 (en) 1997-06-18
KR970705549A (ko) 1997-10-09
CN1098843C (zh) 2003-01-15
MX9701630A (es) 1997-06-28

Similar Documents

Publication Publication Date Title
NO970892L (no) Isoksazolderivater
ATE180468T1 (de) Anthranilsäure derivate
ATE286026T1 (de) Amid-derivate und deren medizinische verwendung
NZ330973A (en) Azolobenzazepine derivatives as neurologically active agents
NO20020968L (no) Glukopyranosyloksypyrazolderivater, medisinske sammensetninger inneholdende det samme og intermediater forfremstillingen derav
AU7517400A (en) N-substituted 4-aminopteridines, synthesis and use thereof as pharmaceutical agent
PT918776E (pt) Sintese total de acilfulvenos antitumorais
AU5162396A (en) Protective agent for organ or tissue
EP0885891A4 (en) ISOXAZOLE DERIVATIVES
DE69828197D1 (de) Amidderivate zur behandlung neurodegenerativer erkrankungen der netzhaut
EP0889033A4 (no)
NO20012443L (no) Benzoksazolderivater og legemidler inneholdende disse som aktiv bestanddel
ES2168119T3 (es) Derivados de quinoxalina para el tratamiento de tinnitus.
AU6118798A (en) Remedies for peripheral circulation disturbances