NO965207L - Sammensetning for indusering av mukosal immunrespons - Google Patents
Sammensetning for indusering av mukosal immunresponsInfo
- Publication number
- NO965207L NO965207L NO965207A NO965207A NO965207L NO 965207 L NO965207 L NO 965207L NO 965207 A NO965207 A NO 965207A NO 965207 A NO965207 A NO 965207A NO 965207 L NO965207 L NO 965207L
- Authority
- NO
- Norway
- Prior art keywords
- immune response
- antigen
- inducing
- composition
- site
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/812—Liposome comprising an antibody, antibody fragment, antigen, or other specific or nonspecific immunoeffector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Farmasøytisk sammensetning er beskrevet for indusering av en beskyttende immunrespons overfor et antigen i et mukosal effektor sete i et vertspattedyr. Sammensetningen innbefatter minst to identiske eller forskjellige komponenter som hver inneholder et immunrespons induserende middel valgt fra antigen, forutsatt at antigenet er et proteinantigen, og en ekspresjonskassett som har evne til å uttrykke antigenet, for samtidig eller påfølgende administrering. En av komponentene er formulert for nasal/oral levering slik at induseringsmiddelet blir målsøkt til immunrespons induserende sete (er) i nese/oral hulrom/pharynx eller spyttkjertler, mens den andre komponenten er formulert for egnet mukosal levering forskjellig fra nasal levering slik at induseringsmiddelet blir målsøkt til immunresponsinduserende sete(er) ved effektorsetet, hvor en immunrespons er ønsket. Nevnte sammensetning kan eventuelt også innbefatte en tredje komponent som er identisk med eller forskjellig fra de første to komponentene og formulert for systemisk administrering.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9504433A FR2732605B1 (fr) | 1995-04-07 | 1995-04-07 | Composition destinee a l'induction d'une reponse immunitaire mucosale |
PCT/FR1996/000534 WO1996031235A1 (fr) | 1995-04-07 | 1996-04-09 | Composition destinee a l'induction d'une reponse immunitaire mucosale |
Publications (2)
Publication Number | Publication Date |
---|---|
NO965207D0 NO965207D0 (no) | 1996-12-05 |
NO965207L true NO965207L (no) | 1996-12-05 |
Family
ID=9478070
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO965207A NO965207L (no) | 1995-04-07 | 1996-12-05 | Sammensetning for indusering av mukosal immunrespons |
Country Status (10)
Country | Link |
---|---|
US (1) | US6126938A (no) |
EP (1) | EP0765170A1 (no) |
JP (1) | JPH10501556A (no) |
AU (1) | AU5504996A (no) |
CA (1) | CA2192473A1 (no) |
FR (1) | FR2732605B1 (no) |
HU (1) | HUP9700037A3 (no) |
NO (1) | NO965207L (no) |
NZ (1) | NZ306483A (no) |
WO (1) | WO1996031235A1 (no) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6485726B1 (en) * | 1995-01-17 | 2002-11-26 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
GB9626864D0 (en) * | 1996-12-24 | 1997-02-12 | Smithkline Beecham Biolog | Vaccine |
NZ307017A (en) * | 1995-04-28 | 1999-07-29 | Oravax Inc | Vaccine containing multimeric complexes of helicobacter urease, composition of antigen (from gastroduodenal pathogen) and antibiotic, antisecretory agent, and/or bismuth salt |
US20020165183A1 (en) * | 1999-11-29 | 2002-11-07 | Hans Herweijer | Methods for genetic immunization |
US6248551B1 (en) | 1997-03-28 | 2001-06-19 | Institut Pasteur | Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides |
FR2762787B1 (fr) * | 1997-04-30 | 2000-10-06 | Pasteur Merieux Serums Vacc | Composition vaccinale anti-helicobacter comprenant un adjuvant de type th1 |
KR20010020418A (ko) * | 1997-04-30 | 2001-03-15 | 마리에 폴린 에이로레 | Th1-형 면역 보강제를 포함하는 항헬리코박터 백신 조성물 |
FR2762788B1 (fr) * | 1997-04-30 | 2000-10-06 | Pasteur Merieux Serums Vacc | Composition vaccinale anti-helicobacter pour usage par voie systemique sous-diaphragmatique |
EP1073745B1 (en) * | 1998-04-30 | 2004-12-01 | Chiron S.r.l. | Immunization against and treatment for infection by h. pylori |
US6585975B1 (en) * | 1998-04-30 | 2003-07-01 | Acambis, Inc. | Use of Salmonella vectors for vaccination against helicobacter infection |
US6576244B1 (en) * | 1998-06-19 | 2003-06-10 | Acambis, Inc. | LT and CT in parenteral immunization methods against helicobacter infection |
CU22871A1 (es) | 1998-12-02 | 2003-10-21 | Ct Ingenieria Genetica Biotech | Formulaciones conteniendo partículas semejantes a virus como inmunopotenciadores por vía mucosal |
US20040157277A1 (en) * | 2002-03-08 | 2004-08-12 | Clancy Robert Llewellyn | Methods for predicting and/or diagnosing the risk of gastric cancer |
AUPQ854100A0 (en) * | 2000-07-03 | 2000-07-27 | Helirad Pty Ltd | Methods for monitoring treatment of helicobacter infection |
US20040033240A1 (en) * | 2000-07-05 | 2004-02-19 | Bruno Guy | Immunological combinations for prophylaxis and therapy of helicobacter pylori infection |
FR2814958B1 (fr) * | 2000-10-06 | 2003-03-07 | Aventis Pasteur | Composition vaccinale |
US20040016013A1 (en) * | 2002-07-18 | 2004-01-22 | Gonzalo Hortelano | Transgenic animals produced using oral administration of a genetic agent coupled to a transporting agent |
US20040014704A1 (en) * | 2002-07-18 | 2004-01-22 | Gonzalo Hortelano | Oral administration of therapeutic agent coupled to transporting agent induces tolerance |
US7264800B2 (en) * | 2002-07-18 | 2007-09-04 | Helix Biopharma Corporation | Method and composition for inhibiting cancer cell growth |
SI1530482T1 (sl) * | 2002-07-18 | 2014-03-31 | Helix Biopharma Corp. | Uporaba ureaze za inhibiranje rasti rakavih celic |
US20040014698A1 (en) * | 2002-07-18 | 2004-01-22 | Gonzalo Hortelano | Oral administration of therapeutic agent coupled to transporting agent |
MXPA06001674A (es) | 2003-08-12 | 2006-05-12 | 3M Innovative Properties Co | Compuestos que contienen imidazo hidroxilamina-sustituidos. |
EP1658076B1 (en) | 2003-08-27 | 2013-03-06 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted imidazoquinolines |
EP1660026A4 (en) | 2003-09-05 | 2008-07-16 | 3M Innovative Properties Co | TREATMENT FOR CD5 + B CELL LYMPHOMA |
AU2004278014B2 (en) | 2003-10-03 | 2011-04-28 | 3M Innovative Properties Company | Alkoxy substituted imidazoquinolines |
US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
EP1685129A4 (en) | 2003-11-14 | 2008-10-22 | 3M Innovative Properties Co | OXIMSUBSTITUTED IMIDAZORING CONNECTIONS |
CN1906192A (zh) | 2003-11-14 | 2007-01-31 | 3M创新有限公司 | 羟胺取代的咪唑环化合物 |
AR046781A1 (es) | 2003-11-25 | 2005-12-21 | 3M Innovative Properties Co | Derivados de imidazoquinolinas. composiciones farmaceuticas. |
US7198785B2 (en) * | 2003-12-09 | 2007-04-03 | Brown University | Systems and methods related to degradation of uremic toxins |
WO2005066170A1 (en) | 2003-12-29 | 2005-07-21 | 3M Innovative Properties Company | Arylalkenyl and arylalkynyl substituted imidazoquinolines |
CA2551399A1 (en) | 2003-12-30 | 2005-07-21 | 3M Innovative Properties Company | Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides |
US20050208032A1 (en) * | 2004-01-16 | 2005-09-22 | Gonzalo Hortelano | Oral administration of therapeutic agent coupled to transporting agent |
WO2005094531A2 (en) | 2004-03-24 | 2005-10-13 | 3M Innovative Properties Company | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
WO2005123080A2 (en) | 2004-06-15 | 2005-12-29 | 3M Innovative Properties Company | Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines |
WO2006065280A2 (en) | 2004-06-18 | 2006-06-22 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods |
WO2006009826A1 (en) | 2004-06-18 | 2006-01-26 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines |
WO2006038923A2 (en) | 2004-06-18 | 2006-04-13 | 3M Innovative Properties Company | Aryl substituted imidazonaphthyridines |
AU2005322898B2 (en) | 2004-12-30 | 2011-11-24 | 3M Innovative Properties Company | Chiral fused (1,2)imidazo(4,5-c) ring compounds |
EP1831221B1 (en) | 2004-12-30 | 2012-08-08 | 3M Innovative Properties Company | Substituted chiral fused 1,2 imidazo 4,5-c ring compounds |
US20080119508A1 (en) * | 2004-12-30 | 2008-05-22 | 3M Innovative Properties Company | Multi-Route Administration Of Immune Response Modifier Compounds |
JP2008530022A (ja) | 2005-02-04 | 2008-08-07 | コーリー ファーマシューティカル グループ,インコーポレイテッド | 免疫反応調節物質を含む水性ゲル処方物 |
AU2006213746A1 (en) | 2005-02-11 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted imidazo(4,5-c) ring compounds and methods |
JP2008535832A (ja) | 2005-04-01 | 2008-09-04 | コーリー ファーマシューティカル グループ,インコーポレイテッド | ピラゾロピリジン−1,4−ジアミン、およびそのアナログ |
US7943636B2 (en) | 2005-04-01 | 2011-05-17 | 3M Innovative Properties Company | 1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases |
WO2008008432A2 (en) | 2006-07-12 | 2008-01-17 | Coley Pharmaceutical Group, Inc. | Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6024983A (en) * | 1986-10-24 | 2000-02-15 | Southern Research Institute | Composition for delivering bioactive agents for immune response and its preparation |
US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
GB2237510B (en) * | 1989-11-04 | 1993-09-15 | Danbiosyst Uk | Small particle drug compositions for nasal administration |
MX9301706A (es) * | 1992-04-13 | 1994-05-31 | Oravax Inc | Composicion de vacuna para el tratamiento de la infeccion por helicobacter. |
US5562909A (en) * | 1993-07-12 | 1996-10-08 | Massachusetts Institute Of Technology | Phosphazene polyelectrolytes as immunoadjuvants |
KR100333113B1 (ko) * | 1993-07-27 | 2002-11-27 | 시에스엘 리미티드 | 헬리코박터피롤리관련위십이지장질환의치료방법 |
JPH09512177A (ja) * | 1994-04-29 | 1997-12-09 | ファルマシア・アンド・アップジョン・カンパニー | ネコ免疫不全ウイルスワクチン |
US5897475A (en) * | 1994-10-05 | 1999-04-27 | Antex Biologics, Inc. | Vaccines comprising enhanced antigenic helicobacter spp. |
GB9503824D0 (en) | 1995-02-25 | 1995-04-19 | Allen Jones James | Oil-slick containment |
-
1995
- 1995-04-07 FR FR9504433A patent/FR2732605B1/fr not_active Expired - Fee Related
-
1996
- 1996-04-09 AU AU55049/96A patent/AU5504996A/en not_active Abandoned
- 1996-04-09 HU HU9700037A patent/HUP9700037A3/hu unknown
- 1996-04-09 CA CA002192473A patent/CA2192473A1/en not_active Abandoned
- 1996-04-09 WO PCT/FR1996/000534 patent/WO1996031235A1/fr not_active Application Discontinuation
- 1996-04-09 NZ NZ306483A patent/NZ306483A/en unknown
- 1996-04-09 JP JP8530055A patent/JPH10501556A/ja active Pending
- 1996-04-09 EP EP96912086A patent/EP0765170A1/fr not_active Ceased
- 1996-12-05 NO NO965207A patent/NO965207L/no not_active Application Discontinuation
-
1998
- 1998-02-04 US US09/018,460 patent/US6126938A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1996031235A1 (fr) | 1996-10-10 |
JPH10501556A (ja) | 1998-02-10 |
AU5504996A (en) | 1996-10-23 |
NZ306483A (en) | 1998-08-26 |
FR2732605A1 (fr) | 1996-10-11 |
EP0765170A1 (fr) | 1997-04-02 |
MX9606195A (es) | 1998-06-28 |
HUP9700037A3 (en) | 2002-04-29 |
FR2732605B1 (fr) | 1997-05-16 |
CA2192473A1 (en) | 1996-10-10 |
US6126938A (en) | 2000-10-03 |
HUP9700037A2 (hu) | 1998-10-28 |
NO965207D0 (no) | 1996-12-05 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |