FR2732605B1 - Composition destinee a l'induction d'une reponse immunitaire mucosale - Google Patents

Composition destinee a l'induction d'une reponse immunitaire mucosale

Info

Publication number
FR2732605B1
FR2732605B1 FR9504433A FR9504433A FR2732605B1 FR 2732605 B1 FR2732605 B1 FR 2732605B1 FR 9504433 A FR9504433 A FR 9504433A FR 9504433 A FR9504433 A FR 9504433A FR 2732605 B1 FR2732605 B1 FR 2732605B1
Authority
FR
France
Prior art keywords
composition
immune response
mucosal immune
inducing mucosal
inducing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9504433A
Other languages
English (en)
Other versions
FR2732605A1 (fr
Inventor
Bruno Guy
Jean Haensler
Millet Marie Jose Quentin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Pasteur Merieux Serum et Vaccines SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9504433A priority Critical patent/FR2732605B1/fr
Application filed by Pasteur Merieux Serum et Vaccines SA filed Critical Pasteur Merieux Serum et Vaccines SA
Priority to EP96912086A priority patent/EP0765170A1/fr
Priority to HU9700037A priority patent/HUP9700037A3/hu
Priority to JP8530055A priority patent/JPH10501556A/ja
Priority to NZ306483A priority patent/NZ306483A/en
Priority to CA002192473A priority patent/CA2192473A1/fr
Priority to PCT/FR1996/000534 priority patent/WO1996031235A1/fr
Priority to AU55049/96A priority patent/AU5504996A/en
Publication of FR2732605A1 publication Critical patent/FR2732605A1/fr
Priority to NO965207A priority patent/NO965207D0/no
Priority to MXPA/A/1996/006195A priority patent/MXPA96006195A/xx
Application granted granted Critical
Publication of FR2732605B1 publication Critical patent/FR2732605B1/fr
Priority to US09/018,460 priority patent/US6126938A/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/812—Liposome comprising an antibody, antibody fragment, antigen, or other specific or nonspecific immunoeffector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR9504433A 1995-04-07 1995-04-07 Composition destinee a l'induction d'une reponse immunitaire mucosale Expired - Fee Related FR2732605B1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR9504433A FR2732605B1 (fr) 1995-04-07 1995-04-07 Composition destinee a l'induction d'une reponse immunitaire mucosale
AU55049/96A AU5504996A (en) 1995-04-07 1996-04-09 Composition for inducing a mucosal immune response
JP8530055A JPH10501556A (ja) 1995-04-07 1996-04-09 粘膜性免疫応答誘発用組成物
NZ306483A NZ306483A (en) 1995-04-07 1996-04-09 Composition for inducing a mucosal immune response administered by two different routes
CA002192473A CA2192473A1 (fr) 1995-04-07 1996-04-09 Composition destinee a l'induction d'une reponse immunitaire mucosale
PCT/FR1996/000534 WO1996031235A1 (fr) 1995-04-07 1996-04-09 Composition destinee a l'induction d'une reponse immunitaire mucosale
EP96912086A EP0765170A1 (fr) 1995-04-07 1996-04-09 Composition destinee a l'induction d'une reponse immunitaire mucosale
HU9700037A HUP9700037A3 (en) 1995-04-07 1996-04-09 Composition for inducing a mucosal immune response
NO965207A NO965207D0 (no) 1995-04-07 1996-12-05 Sammensetning for indusering av mukosal immunrespons
MXPA/A/1996/006195A MXPA96006195A (en) 1995-04-07 1996-12-06 Composition to induce an immune response mucos
US09/018,460 US6126938A (en) 1995-04-07 1998-02-04 Methods for inducing a mucosal immune response

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9504433A FR2732605B1 (fr) 1995-04-07 1995-04-07 Composition destinee a l'induction d'une reponse immunitaire mucosale

Publications (2)

Publication Number Publication Date
FR2732605A1 FR2732605A1 (fr) 1996-10-11
FR2732605B1 true FR2732605B1 (fr) 1997-05-16

Family

ID=9478070

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9504433A Expired - Fee Related FR2732605B1 (fr) 1995-04-07 1995-04-07 Composition destinee a l'induction d'une reponse immunitaire mucosale

Country Status (10)

Country Link
US (1) US6126938A (fr)
EP (1) EP0765170A1 (fr)
JP (1) JPH10501556A (fr)
AU (1) AU5504996A (fr)
CA (1) CA2192473A1 (fr)
FR (1) FR2732605B1 (fr)
HU (1) HUP9700037A3 (fr)
NO (1) NO965207D0 (fr)
NZ (1) NZ306483A (fr)
WO (1) WO1996031235A1 (fr)

Families Citing this family (46)

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US6485726B1 (en) * 1995-01-17 2002-11-26 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of therapeutics
GB9626864D0 (en) * 1996-12-24 1997-02-12 Smithkline Beecham Biolog Vaccine
ATE433325T1 (de) * 1995-04-28 2009-06-15 Merieux Oravax Snc Multimerer, rekombinanter urease impfstoff
US20020165183A1 (en) * 1999-11-29 2002-11-07 Hans Herweijer Methods for genetic immunization
US6248551B1 (en) 1997-03-28 2001-06-19 Institut Pasteur Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides
AU750379B2 (en) * 1997-04-30 2002-07-18 Merieux Oravax Anti-helicobacter vaccine composition comprising a Th1 adjuvant
FR2762787B1 (fr) * 1997-04-30 2000-10-06 Pasteur Merieux Serums Vacc Composition vaccinale anti-helicobacter comprenant un adjuvant de type th1
FR2762788B1 (fr) * 1997-04-30 2000-10-06 Pasteur Merieux Serums Vacc Composition vaccinale anti-helicobacter pour usage par voie systemique sous-diaphragmatique
US6585975B1 (en) * 1998-04-30 2003-07-01 Acambis, Inc. Use of Salmonella vectors for vaccination against helicobacter infection
JP4346821B2 (ja) * 1998-04-30 2009-10-21 カイロン ソチエタ ア レスポンサビリタ リミタータ Ｈ．Ｐｙｌｏｒｉによる感染に対する免疫化および処置
JP2002518343A (ja) * 1998-06-19 2002-06-25 メリウクス オラバクス ヘリコバクター感染に対する非経口的免疫処置法におけるｌｔおよびｃｔ
CU22871A1 (es) 1998-12-02 2003-10-21 Ct Ingenieria Genetica Biotech Formulaciones conteniendo partículas semejantes a virus como inmunopotenciadores por vía mucosal
US20040157277A1 (en) * 2002-03-08 2004-08-12 Clancy Robert Llewellyn Methods for predicting and/or diagnosing the risk of gastric cancer
AUPQ854100A0 (en) * 2000-07-03 2000-07-27 Helirad Pty Ltd Methods for monitoring treatment of helicobacter infection
US20040033240A1 (en) * 2000-07-05 2004-02-19 Bruno Guy Immunological combinations for prophylaxis and therapy of helicobacter pylori infection
FR2814958B1 (fr) * 2000-10-06 2003-03-07 Aventis Pasteur Composition vaccinale
AU2003250658B2 (en) * 2002-07-18 2009-07-16 Helix Biopharma Corp. Use of urease for inhibiting cancer cell growth
US20040016013A1 (en) * 2002-07-18 2004-01-22 Gonzalo Hortelano Transgenic animals produced using oral administration of a genetic agent coupled to a transporting agent
US20040014698A1 (en) * 2002-07-18 2004-01-22 Gonzalo Hortelano Oral administration of therapeutic agent coupled to transporting agent
US20040014704A1 (en) * 2002-07-18 2004-01-22 Gonzalo Hortelano Oral administration of therapeutic agent coupled to transporting agent induces tolerance
US7264800B2 (en) * 2002-07-18 2007-09-04 Helix Biopharma Corporation Method and composition for inhibiting cancer cell growth
TW200524927A (en) 2003-08-12 2005-08-01 3M Innovative Properties Co Hydroxylamine substituted imidazo-containing compounds
RU2006105101A (ru) 2003-08-27 2007-10-10 3М Инновейтив Пропертиз Компани (US) Арилокси и арилалкиленокси замещенные имидазохинолины
EP1660026A4 (fr) 2003-09-05 2008-07-16 3M Innovative Properties Co Traitement pour le lymphome a cellules b cd5+
CN1897948A (zh) 2003-10-03 2007-01-17 3M创新有限公司 烷氧基取代的咪唑并喹啉
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
US7897767B2 (en) 2003-11-14 2011-03-01 3M Innovative Properties Company Oxime substituted imidazoquinolines
AU2004291122A1 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Hydroxylamine substituted imidazo ring compounds
CA2547020C (fr) 2003-11-25 2014-03-25 3M Innovative Properties Company Derives de 1h-imidazo[4,5-c]pyridine-4-amine en tant que compose modificateur de la reponse immunitaire
US7198785B2 (en) * 2003-12-09 2007-04-03 Brown University Systems and methods related to degradation of uremic toxins
JP2007517035A (ja) 2003-12-29 2007-06-28 スリーエム イノベイティブ プロパティズ カンパニー アリールアルケニルおよびアリールアルキニル置換されたイミダゾキノリン
CA2551399A1 (fr) 2003-12-30 2005-07-21 3M Innovative Properties Company Sulfonamides d'imidazoquinolinyle, d'imidazopyridinyle et d'imidazonaphtyridinyle
US20050208032A1 (en) * 2004-01-16 2005-09-22 Gonzalo Hortelano Oral administration of therapeutic agent coupled to transporting agent
TW200612932A (en) 2004-03-24 2006-05-01 3M Innovative Properties Co Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en) 2004-06-15 2011-09-13 3M Innovative Properties Company Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
US7897609B2 (en) 2004-06-18 2011-03-01 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
US7915281B2 (en) 2004-06-18 2011-03-29 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
WO2006009826A1 (fr) 2004-06-18 2006-01-26 3M Innovative Properties Company Thiazoloquinolines et thiazolonaphtyridines substitues par aryloxy et arylalkyleneoxy
AU2005326708C1 (en) 2004-12-30 2012-08-30 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
ES2392647T3 (es) 2004-12-30 2012-12-12 3M Innovative Properties Company Compuestos tetracíclicos quirales que inducen la biosíntesis de interferón
AU2005322843B2 (en) * 2004-12-30 2012-03-08 3M Innovative Properties Company Immune response modifier formulations and methods
JP2008530022A (ja) 2005-02-04 2008-08-07 コーリー ファーマシューティカル グループ，インコーポレイテッド 免疫反応調節物質を含む水性ゲル処方物
CA2597587A1 (fr) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Composes cycliques imidazo[4,5-c] substitues par oxime et hydroxylamine et procedes associes
US7943636B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company 1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
US7943610B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company Pyrazolopyridine-1,4-diamines and analogs thereof
US7906506B2 (en) 2006-07-12 2011-03-15 3M Innovative Properties Company Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods

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MX9301706A (es) * 1992-04-13 1994-05-31 Oravax Inc Composicion de vacuna para el tratamiento de la infeccion por helicobacter.
US5562909A (en) * 1993-07-12 1996-10-08 Massachusetts Institute Of Technology Phosphazene polyelectrolytes as immunoadjuvants
KR100333113B1 (ko) * 1993-07-27 2002-11-27 시에스엘 리미티드 헬리코박터피롤리관련위십이지장질환의치료방법
US5833993A (en) * 1994-04-29 1998-11-10 Pharmacia & Upjohn Company Feline immunodeficiency virus vaccine
US5681736A (en) * 1994-10-05 1997-10-28 Antex Biologics, Inc. Methods for producing enhanced antigenic shigella bacteria and vaccines comprising same
GB9503824D0 (en) 1995-02-25 1995-04-19 Allen Jones James Oil-slick containment

Also Published As

Publication number Publication date
AU5504996A (en) 1996-10-23
EP0765170A1 (fr) 1997-04-02
NZ306483A (en) 1998-08-26
JPH10501556A (ja) 1998-02-10
CA2192473A1 (fr) 1996-10-10
HUP9700037A3 (en) 2002-04-29
NO965207L (no) 1996-12-05
HUP9700037A2 (hu) 1998-10-28
WO1996031235A1 (fr) 1996-10-10
FR2732605A1 (fr) 1996-10-11
US6126938A (en) 2000-10-03
MX9606195A (es) 1998-06-28
NO965207D0 (no) 1996-12-05

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