NO964434L - Bicykliske tiofenderivater og anvendelse som gonadotropinfrigivende hormonantagonister - Google Patents

Bicykliske tiofenderivater og anvendelse som gonadotropinfrigivende hormonantagonister

Info

Publication number
NO964434L
NO964434L NO964434A NO964434A NO964434L NO 964434 L NO964434 L NO 964434L NO 964434 A NO964434 A NO 964434A NO 964434 A NO964434 A NO 964434A NO 964434 L NO964434 L NO 964434L
Authority
NO
Norway
Prior art keywords
agent
cancer
hormone
homo
hetero
Prior art date
Application number
NO964434A
Other languages
English (en)
Norwegian (no)
Other versions
NO964434D0 (no
Inventor
Shuichi Furuya
Nobuo Choh
Koichi Kato
Shuj Hinuma
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO964434L publication Critical patent/NO964434L/no
Publication of NO964434D0 publication Critical patent/NO964434D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO964434A 1994-04-19 1996-10-18 Bicykliske tiofenderivater og anvendelse som gonadotropinfrigivende hormonantagonister NO964434D0 (no)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP8073294 1994-04-19
JP19554194 1994-08-19
JP27101094 1994-11-04
JP2071795 1995-02-08
JP4015195 1995-02-28
PCT/JP1995/000728 WO1995028405A1 (en) 1994-04-19 1995-04-14 Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists

Publications (2)

Publication Number Publication Date
NO964434L true NO964434L (no) 1996-10-18
NO964434D0 NO964434D0 (no) 1996-10-18

Family

ID=27520246

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964434A NO964434D0 (no) 1994-04-19 1996-10-18 Bicykliske tiofenderivater og anvendelse som gonadotropinfrigivende hormonantagonister

Country Status (17)

Country Link
US (3) US5817819A (cs)
EP (1) EP0756599B1 (cs)
KR (1) KR970702282A (cs)
CN (1) CN1092197C (cs)
AT (1) ATE255113T1 (cs)
AU (2) AU697472B2 (cs)
CA (1) CA2186124A1 (cs)
CZ (1) CZ290713B6 (cs)
DE (1) DE69532194T2 (cs)
FI (2) FI964195A7 (cs)
HU (1) HUT76320A (cs)
NO (1) NO964434D0 (cs)
NZ (1) NZ283813A (cs)
OA (1) OA10331A (cs)
PL (1) PL316796A1 (cs)
TW (1) TW449600B (cs)
WO (1) WO1995028405A1 (cs)

Families Citing this family (70)

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US5849764A (en) * 1995-12-14 1998-12-15 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
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US6015789A (en) * 1996-04-30 2000-01-18 Takeda Chemical Industries, Ltd. Combined use of GnRH agonist and antagonist
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US6297255B1 (en) 1998-06-26 2001-10-02 Takeda Chemical Industries, Ltd. Thienopyridine compounds, their production and use
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US6239142B1 (en) 1999-03-09 2001-05-29 Pharmacia & Upjohn Company 4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5carboxamides as antiviral agents
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WO2003020728A1 (en) 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
AR038117A1 (es) 2002-01-14 2004-12-29 Upjohn Co Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
AR038118A1 (es) 2002-01-14 2004-12-29 Upjohn Co Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
AR038294A1 (es) 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
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CA2481391A1 (en) * 2002-04-12 2003-10-23 Takeda Pharmaceutical Company Limited Preventives/remedies for hotflash
BR0312744A (pt) * 2002-07-17 2005-04-26 Warner Lambert Co Associação de um inibidor carboxìlico alostérico da metaloproteinase-13 de matriz com um inibidor selectivo da ciclooxigenase-2, à excepção do celecoxib ou valdecoxib
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US7612078B2 (en) * 2003-03-31 2009-11-03 Epix Delaware, Inc. Piperidinylamino-thieno[2,3-D] pyrimidine compounds
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DE102004033902A1 (de) 2004-07-14 2006-02-16 Zentaris Gmbh Neue Tetrahydrocarbazolderivate mit verbesserter biologischer Wirkung und verbesserter Löslichkeit als Liganden für G-Protein gekoppelte Rezeptoren (GPCR's)
US7576211B2 (en) * 2004-09-30 2009-08-18 Epix Delaware, Inc. Synthesis of thienopyridinone compounds and related intermediates
US7598265B2 (en) * 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
US7407966B2 (en) * 2004-10-07 2008-08-05 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
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EP2147922B1 (en) 2007-04-18 2017-08-02 Kissei Pharmaceutical Co., Ltd. Fused heterocyclic derivative, pharmaceutical composition comprising the derivative, and use of the composition for medical purposes
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EP2445877B1 (en) * 2008-12-03 2014-07-23 Nanotherapeutics, Inc. Bicyclic compounds and methods of making and using same
CN102746319B (zh) * 2012-07-25 2015-08-05 中国科学院长春应用化学研究所 一种噻吩并吡啶酮类化合物的制备方法
FI3263110T3 (fi) 2015-02-26 2023-07-25 Takeda Pharmaceuticals Co Tabletti, joka käsittää metoksiureajohdannaista ja mannitolipartikkeleita
WO2019072478A1 (en) * 2017-10-10 2019-04-18 Galderma Research & Development SPECIFIC ACETYL-COA CARBOXYLASE INHIBITORS FOR USE IN THE TREATMENT AND / OR PREVENTION OF ACNE
WO2021018105A1 (en) * 2019-07-29 2021-02-04 Sunshine Lake Pharma Co., Ltd. Substituted pyrimidinedione compounds and uses thereof
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CN113754679B (zh) * 2020-09-09 2023-04-07 广东东阳光药业有限公司 取代的嘧啶二酮类化合物及其用途
WO2022067566A1 (zh) * 2020-09-29 2022-04-07 广东东阳光药业有限公司 含有饱和含氧杂环基的嘧啶二酮类化合物及其用途
CN114369704B (zh) * 2021-12-20 2023-12-26 无锡鹰贝精密液压有限公司 一种减小内球面变形的低碳合金钢球窝柱塞热处理方法
TW202408511A (zh) 2022-08-05 2024-03-01 美商基利科學股份有限公司 Ｓａｒｓ－ｃｏｖ２主蛋白酶抑制劑

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Also Published As

Publication number Publication date
CA2186124A1 (en) 1995-10-26
PL316796A1 (en) 1997-02-17
TW449600B (en) 2001-08-11
EP0756599B1 (en) 2003-11-26
FI964195A0 (fi) 1996-10-18
ATE255113T1 (de) 2003-12-15
CZ302896A3 (en) 1997-05-14
HUT76320A (en) 1997-08-28
OA10331A (en) 1997-10-07
AU713116B2 (en) 1999-11-25
AU697472B2 (en) 1998-10-08
AU8316998A (en) 1998-11-05
KR970702282A (ko) 1997-05-13
HU9602884D0 (en) 1996-12-30
DE69532194D1 (de) 2004-01-08
AU2223995A (en) 1995-11-10
US6187788B1 (en) 2001-02-13
FI20012326A7 (fi) 2001-11-28
WO1995028405A1 (en) 1995-10-26
CZ290713B6 (cs) 2002-09-11
EP0756599A1 (en) 1997-02-05
FI20012326L (fi) 2001-11-28
US5817819A (en) 1998-10-06
NO964434D0 (no) 1996-10-18
CN1092197C (zh) 2002-10-09
FI964195A7 (fi) 1996-12-17
CN1146206A (zh) 1997-03-26
DE69532194T2 (de) 2004-09-09
US6514988B1 (en) 2003-02-04
NZ283813A (en) 1998-11-25

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