NO961796L - Rekombinante fedme (ob) proteiner - Google Patents

Rekombinante fedme (ob) proteiner

Info

Publication number
NO961796L
NO961796L NO961796A NO961796A NO961796L NO 961796 L NO961796 L NO 961796L NO 961796 A NO961796 A NO 961796A NO 961796 A NO961796 A NO 961796A NO 961796 L NO961796 L NO 961796L
Authority
NO
Norway
Prior art keywords
proteins
obesity
recombinant
recombinant obesity
Prior art date
Application number
NO961796A
Other languages
English (en)
Other versions
NO961796D0 (no
Inventor
Arthur Campfield
Rene Devos
Yves Guisez
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO961796D0 publication Critical patent/NO961796D0/no
Publication of NO961796L publication Critical patent/NO961796L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO961796A 1995-05-05 1996-05-03 Rekombinante fedme (ob) proteiner NO961796L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43577795A 1995-05-05 1995-05-05
US48462995A 1995-06-07 1995-06-07

Publications (2)

Publication Number Publication Date
NO961796D0 NO961796D0 (no) 1996-05-03
NO961796L true NO961796L (no) 1996-11-06

Family

ID=27030682

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961796A NO961796L (no) 1995-05-05 1996-05-03 Rekombinante fedme (ob) proteiner

Country Status (35)

Country Link
US (1) US6025325A (no)
EP (1) EP0741187A2 (no)
JP (1) JP3244627B2 (no)
KR (1) KR100219970B1 (no)
CN (1) CN1157290A (no)
AR (1) AR003087A1 (no)
AU (1) AU688210B2 (no)
BG (1) BG62975B1 (no)
BR (1) BR9602166A (no)
CA (1) CA2175298A1 (no)
CZ (1) CZ129796A3 (no)
DE (1) DE741187T1 (no)
ES (1) ES2093593T1 (no)
GR (1) GR960300075T1 (no)
HR (1) HRP960213A2 (no)
HU (1) HU220093B (no)
IL (1) IL118059A0 (no)
IS (1) IS4343A (no)
MA (1) MA23856A1 (no)
MY (1) MY132189A (no)
NO (1) NO961796L (no)
NZ (1) NZ286466A (no)
OA (1) OA10362A (no)
PE (1) PE50897A1 (no)
PL (1) PL186568B1 (no)
RO (1) RO117177B1 (no)
RU (1) RU96109211A (no)
SG (1) SG49337A1 (no)
SK (1) SK56996A3 (no)
SV (1) SV1996000030A (no)
TN (1) TNSN96066A1 (no)
TR (1) TR199600357A2 (no)
TW (1) TW464655B (no)
UY (1) UY24219A1 (no)
YU (1) YU26596A (no)

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US6309853B1 (en) 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
US6124448A (en) * 1994-08-17 2000-09-26 The Rockfeller University Nucleic acid primers and probes for the mammalian OB gene
US6048837A (en) * 1994-08-17 2000-04-11 The Rockefeller University OB polypeptides as modulators of body weight
US20030040467A1 (en) * 1998-06-15 2003-02-27 Mary Ann Pelleymounter Ig/ob fusions and uses thereof.
US6936439B2 (en) * 1995-11-22 2005-08-30 Amgen Inc. OB fusion protein compositions and methods
US6620413B1 (en) 1995-12-27 2003-09-16 Genentech, Inc. OB protein-polymer chimeras
AU769250B2 (en) * 1995-12-27 2004-01-22 Genentech Inc. OB protein derivatives having prolonged half-life
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US7074397B1 (en) 1996-01-08 2006-07-11 Genentech, Inc. Method for enhancing proliferation or differentiation of a cell using ob protein
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US6867183B2 (en) * 2001-02-15 2005-03-15 Nobex Corporation Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7060675B2 (en) * 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
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Also Published As

Publication number Publication date
PL314051A1 (en) 1996-11-12
MY132189A (en) 2007-09-28
HRP960213A2 (en) 1997-10-31
NZ286466A (en) 1998-03-25
CN1157290A (zh) 1997-08-20
HU9601120D0 (en) 1996-06-28
SG49337A1 (en) 1998-05-18
MA23856A1 (fr) 1996-12-31
HU220093B (hu) 2001-10-28
UY24219A1 (es) 2001-03-16
JPH093098A (ja) 1997-01-07
YU26596A (sh) 1999-03-04
PL186568B1 (pl) 2004-01-30
JP3244627B2 (ja) 2002-01-07
TNSN96066A1 (fr) 2005-03-15
MX9601655A (es) 1997-07-31
BG62975B1 (bg) 2000-12-29
SK56996A3 (en) 1997-04-09
CA2175298A1 (en) 1996-11-06
KR960041194A (ko) 1996-12-19
RU96109211A (ru) 1998-10-27
EP0741187A3 (no) 1996-12-11
HUP9601120A2 (en) 1996-11-28
CZ129796A3 (en) 1997-01-15
HUP9601120A3 (en) 1999-07-28
SV1996000030A (es) 1999-01-14
US6025325A (en) 2000-02-15
DE741187T1 (de) 1997-04-30
TR199600357A2 (tr) 1996-11-21
BR9602166A (pt) 1998-01-13
BG100558A (bg) 1997-03-31
EP0741187A2 (en) 1996-11-06
AU688210B2 (en) 1998-03-05
TW464655B (en) 2001-11-21
PE50897A1 (es) 1997-12-19
NO961796D0 (no) 1996-05-03
AR003087A1 (es) 1998-07-08
KR100219970B1 (ko) 1999-10-01
OA10362A (fr) 2001-11-15
GR960300075T1 (en) 1996-12-31
IS4343A (is) 1996-12-09
AU5197896A (en) 1996-11-14
IL118059A0 (en) 1996-08-04
ES2093593T1 (es) 1997-01-01
RO117177B1 (ro) 2001-11-30

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