NO960016L - Nye acylerte pseudopeptider med trifluormetylsubstituert 2-azabicyklo-oktan - Google Patents
Nye acylerte pseudopeptider med trifluormetylsubstituert 2-azabicyklo-oktanInfo
- Publication number
- NO960016L NO960016L NO960016A NO960016A NO960016L NO 960016 L NO960016 L NO 960016L NO 960016 A NO960016 A NO 960016A NO 960016 A NO960016 A NO 960016A NO 960016 L NO960016 L NO 960016L
- Authority
- NO
- Norway
- Prior art keywords
- carbon atoms
- straight chain
- stands
- different
- branched
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Det blir beskrevet nye acylerte pseudopeptider med trifluormetyl-substituerte 2-azabicyklo-oktan med den generelle formel (I) hvor R1 står for en rest med formel eller N. ;x hvor A, D, E, L og T er Ilke eller forskjellige og står for hydrogen, halogen, rettkjedet eller forgrenet alkyl ned opptil 4 karbonatoner, morfollnyl, fenyltlo eller cykloalkyl med 3 til 6 karbonatomer, R2 står for rettkjedet eller forgrenet acyl ned opptil 20 karbonatomer, som eventuelt er substituert med karboksy, med rettkjedet eller forgrenet alkoksykar- bonyl ned opptil 6 karbonatomer eller med en gruppe med formelen -KR3R4, hvor . R3 og 'R4 er like eller forskjellige og «tar for hydrogen, fenyl eller rettkjedet eller forgrenet alkyl ned opptil 6 karbonatomer, står for en rest med formelen -CO-XR5R6 eller P(0)(OR7)(OR8), hvor R8 og R6 har den ovenfor angitte betydning for R3 og R4 og er Ilke eller forskjellige, R7 og R8 er Ilke eller forskjellige og står for hydrogen eller rettkjedet eller forgrenet alkyl med opptil 4 karbonatomer, eller står for rettkjedet eller forgrenet alkoksy med opptil 6 karbonatomer, som eventuelt er substituert med dlfluormetyl, dlfluormetoksy, trlfluonnetoksy eller trlfluormetyl, eller for en rest med formlene HA c", ^° Hf og deres salter.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19500120A DE19500120A1 (de) | 1995-01-04 | 1995-01-04 | Neue acylierte Pseudopeptide mit trifluormethyl-subsstituiertem 2-Azabicyclooctan |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO960016D0 NO960016D0 (no) | 1996-01-03 |
| NO960016L true NO960016L (no) | 1996-07-05 |
Family
ID=7750986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO960016A NO960016L (no) | 1995-01-04 | 1996-01-03 | Nye acylerte pseudopeptider med trifluormetylsubstituert 2-azabicyklo-oktan |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0720987A1 (no) |
| JP (1) | JPH08259594A (no) |
| KR (1) | KR960029345A (no) |
| CN (1) | CN1134940A (no) |
| AU (1) | AU4067895A (no) |
| CA (1) | CA2166374A1 (no) |
| CZ (1) | CZ1296A3 (no) |
| DE (1) | DE19500120A1 (no) |
| FI (1) | FI960015A (no) |
| HU (1) | HUT74805A (no) |
| IL (1) | IL116622A0 (no) |
| NO (1) | NO960016L (no) |
| NZ (1) | NZ280729A (no) |
| PL (1) | PL312146A1 (no) |
| SK (1) | SK1296A3 (no) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20001420A1 (es) * | 1998-12-23 | 2000-12-18 | Pfizer | Moduladores de ccr5 |
| US6448245B1 (en) | 2000-05-04 | 2002-09-10 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of and compounds for inhibiting calpains |
| CA2547518A1 (en) | 2003-12-12 | 2005-06-30 | Wyeth | Quinolines useful in treating cardiovascular disease |
| JP4831410B2 (ja) | 2006-02-28 | 2011-12-07 | 東亞合成株式会社 | 抗ウイルス性ペプチドおよび抗ウイルス剤 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1408675A (en) | 1973-03-16 | 1975-10-01 | Allen & Hanburys Ltd | Amides derived from quinoxaline |
| CA1340588C (en) * | 1988-06-13 | 1999-06-08 | Balraj Krishan Handa | Amino acid derivatives |
| DE4126485A1 (de) | 1991-08-10 | 1993-02-11 | Bayer Ag | Trifluormethyl-haltige pseudopeptide |
| TW372972B (en) | 1992-10-23 | 1999-11-01 | Novartis Ag | Antiretroviral acyl compounds |
-
1995
- 1995-01-04 DE DE19500120A patent/DE19500120A1/de not_active Withdrawn
- 1995-01-04 SK SK12-96A patent/SK1296A3/sk unknown
- 1995-12-21 NZ NZ280729A patent/NZ280729A/en unknown
- 1995-12-22 EP EP95120369A patent/EP0720987A1/de not_active Withdrawn
- 1995-12-27 JP JP7351205A patent/JPH08259594A/ja active Pending
- 1995-12-28 AU AU40678/95A patent/AU4067895A/en not_active Abandoned
- 1995-12-29 CA CA002166374A patent/CA2166374A1/en not_active Abandoned
- 1995-12-29 IL IL11662295A patent/IL116622A0/xx unknown
- 1995-12-29 HU HU9503927A patent/HUT74805A/hu unknown
-
1996
- 1996-01-02 PL PL96312146A patent/PL312146A1/xx unknown
- 1996-01-02 FI FI960015A patent/FI960015A/fi unknown
- 1996-01-03 KR KR1019960000008A patent/KR960029345A/ko not_active Application Discontinuation
- 1996-01-03 CZ CZ9612A patent/CZ1296A3/cs unknown
- 1996-01-03 NO NO960016A patent/NO960016L/no unknown
- 1996-01-04 CN CN96100927A patent/CN1134940A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI960015A (fi) | 1996-07-05 |
| EP0720987A1 (de) | 1996-07-10 |
| PL312146A1 (en) | 1996-07-08 |
| CA2166374A1 (en) | 1996-07-05 |
| NO960016D0 (no) | 1996-01-03 |
| IL116622A0 (en) | 1996-03-31 |
| KR960029345A (ko) | 1996-08-17 |
| HUT74805A (en) | 1997-02-28 |
| HU9503927D0 (en) | 1996-03-28 |
| CN1134940A (zh) | 1996-11-06 |
| AU4067895A (en) | 1996-07-11 |
| CZ1296A3 (en) | 1997-05-14 |
| FI960015A0 (fi) | 1996-01-02 |
| SK1296A3 (en) | 1996-08-07 |
| DE19500120A1 (de) | 1996-07-11 |
| NZ280729A (en) | 1996-08-27 |
| JPH08259594A (ja) | 1996-10-08 |
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