NO954389L - Fosfonosulfonat-squalensyntetase-inhibitor-salter og fremgangsmåte - Google Patents
Fosfonosulfonat-squalensyntetase-inhibitor-salter og fremgangsmåteInfo
- Publication number
- NO954389L NO954389L NO954389A NO954389A NO954389L NO 954389 L NO954389 L NO 954389L NO 954389 A NO954389 A NO 954389A NO 954389 A NO954389 A NO 954389A NO 954389 L NO954389 L NO 954389L
- Authority
- NO
- Norway
- Prior art keywords
- salt
- squalene synthetase
- synthetase inhibitor
- phosphonosulfonate
- inhibitor salts
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- LQHYUUBBIJGBNR-UHFFFAOYSA-N OP(O)(=O)S(O)(=O)=O Chemical compound OP(O)(=O)S(O)(=O)=O LQHYUUBBIJGBNR-UHFFFAOYSA-N 0.000 title abstract 2
- 229940123495 Squalene synthetase inhibitor Drugs 0.000 title abstract 2
- 239000004059 squalene synthase inhibitor Substances 0.000 title abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 3
- QIJIUJYANDSEKG-UHFFFAOYSA-N 2,4,4-trimethylpentan-2-amine Chemical class CC(C)(C)CC(C)(C)N QIJIUJYANDSEKG-UHFFFAOYSA-N 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- JVVXZOOGOGPDRZ-SLFFLAALSA-N [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine Chemical class NC[C@]1(C)CCC[C@]2(C)C3=CC=C(C(C)C)C=C3CC[C@H]21 JVVXZOOGOGPDRZ-SLFFLAALSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- YBRBMKDOPFTVDT-UHFFFAOYSA-N tert-butylamine Chemical class CC(C)(C)N YBRBMKDOPFTVDT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4075—Esters with hydroxyalkyl compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33366194A | 1994-11-03 | 1994-11-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO954389D0 NO954389D0 (no) | 1995-11-02 |
NO954389L true NO954389L (no) | 1996-05-06 |
Family
ID=23303735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO954389A NO954389L (no) | 1994-11-03 | 1995-11-02 | Fosfonosulfonat-squalensyntetase-inhibitor-salter og fremgangsmåte |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0710665A1 (de) |
JP (1) | JPH08208672A (de) |
KR (1) | KR960017680A (de) |
CN (1) | CN1130188A (de) |
AU (1) | AU3458795A (de) |
CA (1) | CA2159850A1 (de) |
CZ (1) | CZ279595A3 (de) |
FI (1) | FI955256A (de) |
HU (1) | HUT73140A (de) |
IL (1) | IL115537A0 (de) |
NO (1) | NO954389L (de) |
PL (1) | PL311218A1 (de) |
TW (1) | TW318852B (de) |
ZA (1) | ZA959326B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2780974B1 (fr) * | 1998-07-08 | 2001-09-28 | Sod Conseils Rech Applic | Utilisation de derives d'imidazopyrazines pour preparer un medicament destine a traiter les pathologies qui resultent de la formation de la proteine g heterotrimetrique |
WO2002038180A1 (fr) * | 2000-11-09 | 2002-05-16 | Takeda Chemical Industries, Ltd. | Agent haute densite faisant monter le taux de lipoproteine-cholesterol |
CN101198252A (zh) | 2005-04-18 | 2008-06-11 | 加利福尼亚大学董事会 | 用于细菌感染的抗微生物疗法 |
JP5161872B2 (ja) | 2006-05-12 | 2013-03-13 | ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア | 細菌感染に対する抗微生物療法 |
CN101580472B (zh) * | 2009-06-24 | 2013-07-10 | 广西壮族自治区化工研究院 | 1,1'-联-2-萘酚的拆分剂以及拆分方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ248852A (en) * | 1992-10-28 | 1997-06-24 | Squibb & Sons Inc | Alpha-phosphono and phosphinosulphonates and medicaments thereof |
US5312814A (en) * | 1992-12-09 | 1994-05-17 | Bristol-Myers Squibb Co. | α-phosphonocarboxylate squalene synthetase inhibitors |
-
1995
- 1995-10-04 CA CA002159850A patent/CA2159850A1/en not_active Abandoned
- 1995-10-06 IL IL11553795A patent/IL115537A0/xx unknown
- 1995-10-25 CZ CZ952795A patent/CZ279595A3/cs unknown
- 1995-10-26 EP EP95307618A patent/EP0710665A1/de not_active Withdrawn
- 1995-10-27 JP JP7280397A patent/JPH08208672A/ja active Pending
- 1995-11-02 TW TW084111593A patent/TW318852B/zh active
- 1995-11-02 NO NO954389A patent/NO954389L/no unknown
- 1995-11-02 AU AU34587/95A patent/AU3458795A/en not_active Abandoned
- 1995-11-02 PL PL95311218A patent/PL311218A1/xx unknown
- 1995-11-02 FI FI955256A patent/FI955256A/fi not_active Application Discontinuation
- 1995-11-02 HU HU9503136A patent/HUT73140A/hu unknown
- 1995-11-03 KR KR1019950039576A patent/KR960017680A/ko not_active Application Discontinuation
- 1995-11-03 CN CN95119023A patent/CN1130188A/zh active Pending
- 1995-11-03 ZA ZA959326A patent/ZA959326B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
FI955256A (fi) | 1996-05-04 |
HUT73140A (en) | 1996-06-28 |
NO954389D0 (no) | 1995-11-02 |
TW318852B (de) | 1997-11-01 |
CA2159850A1 (en) | 1996-05-04 |
EP0710665A1 (de) | 1996-05-08 |
CN1130188A (zh) | 1996-09-04 |
AU3458795A (en) | 1996-05-09 |
PL311218A1 (en) | 1996-05-13 |
KR960017680A (ko) | 1996-06-17 |
CZ279595A3 (en) | 1996-08-14 |
HU9503136D0 (en) | 1995-12-28 |
FI955256A0 (fi) | 1995-11-02 |
JPH08208672A (ja) | 1996-08-13 |
ZA959326B (en) | 1997-05-05 |
IL115537A0 (en) | 1996-01-19 |
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